melatonin in the thyroid gland - Journal of Physiology and
... hypothalamic-pituitary-thyroid axis, some effects of melatonin have been reported. Thus, it has been described the decrease of thyroid hormone circulating levels after melatonin administration (34, 35), and the central role played by melatonin on the control of iodothyronine-deiodinases and their in ...
... hypothalamic-pituitary-thyroid axis, some effects of melatonin have been reported. Thus, it has been described the decrease of thyroid hormone circulating levels after melatonin administration (34, 35), and the central role played by melatonin on the control of iodothyronine-deiodinases and their in ...
Alterations in Pituitary, Thyroid, Parathyroid, and Adrenal Function
... function usually returns to normal after the child is removed from the constraining environment. The prognosis depends on improvement in behavior and catch-up growth. Family therapy usually is indicated, and foster care may be necessary. Growth Hormone Deficiency in Children. There are seseveral form ...
... function usually returns to normal after the child is removed from the constraining environment. The prognosis depends on improvement in behavior and catch-up growth. Family therapy usually is indicated, and foster care may be necessary. Growth Hormone Deficiency in Children. There are seseveral form ...
2608. BW Mod.Medicine 02/1¥1.6
... revealed a 14 x 20 x 12 mm pituitary macroadenoma extending to the suprasellar cisterna without compression of the chiasma (figure 1). With this information the patient was sent to the department of endocrinology. Typical clinical signs suggesting hypothyroidism were noticed on physical examination. ...
... revealed a 14 x 20 x 12 mm pituitary macroadenoma extending to the suprasellar cisterna without compression of the chiasma (figure 1). With this information the patient was sent to the department of endocrinology. Typical clinical signs suggesting hypothyroidism were noticed on physical examination. ...
Hyperthyroidism and cation pumps in human skeletal muscle
... 0°C in a HEPES-sucrose buffer (pH 7.4) with an Ultra-Turrax homogenizer. To obtain a smaller particle size, the suspension was further homogenized at 0°C using a glass homogenizer with a tightfitting Teflon pestle rotating at 1,000 rpm. Aliquots (0.2 ml) of the homogenate were reacted for 30 s at 0° ...
... 0°C in a HEPES-sucrose buffer (pH 7.4) with an Ultra-Turrax homogenizer. To obtain a smaller particle size, the suspension was further homogenized at 0°C using a glass homogenizer with a tightfitting Teflon pestle rotating at 1,000 rpm. Aliquots (0.2 ml) of the homogenate were reacted for 30 s at 0° ...
Thyroid function in Exhaustion Disorder: Higher prevalence
... geographic narrowed area of the diagnosis the research concerning ED is limited. In order to reduce the individual suffering and society costs, including for sick leave, by prevention and effective treatment, research is needed to investigate the pathophysiology of ED. Important targets for research ...
... geographic narrowed area of the diagnosis the research concerning ED is limited. In order to reduce the individual suffering and society costs, including for sick leave, by prevention and effective treatment, research is needed to investigate the pathophysiology of ED. Important targets for research ...
Adrenal and thyroid function in the fetus and preterm infant Hye Rim
... capacity can be detected in the thyroid of the 10 to 11 week fetus, the capacity of the fetal thyroid gland to reduce iodide trapping in response to excess iodide does not appear until 36 to 40 weeks gestation23). The fetus has a detectable level of thyroid-stimulating hormone (TSH) at gestational a ...
... capacity can be detected in the thyroid of the 10 to 11 week fetus, the capacity of the fetal thyroid gland to reduce iodide trapping in response to excess iodide does not appear until 36 to 40 weeks gestation23). The fetus has a detectable level of thyroid-stimulating hormone (TSH) at gestational a ...
M15_WING3901_02_IRM_C15
... 1. The failure of an endocrine gland to produce sufficient levels of a hormone, or hyposecretion, can have a serious impact on health. 2. The term endocrine literally means “to secrete within.” 3. In the condition known as myxedema, the skin becomes loose and thin. 4. Hyper- means excessive. 5. Hypo ...
... 1. The failure of an endocrine gland to produce sufficient levels of a hormone, or hyposecretion, can have a serious impact on health. 2. The term endocrine literally means “to secrete within.” 3. In the condition known as myxedema, the skin becomes loose and thin. 4. Hyper- means excessive. 5. Hypo ...
Thierry Hertoghe - Terzo Congresso ImeB
... Take 1 to 2 capsules/day of 550 mg red clover capsules 44mg isoflavones: ...
... Take 1 to 2 capsules/day of 550 mg red clover capsules 44mg isoflavones: ...
Ipotiroidismo Non Responsivo Alla Terapia Come Inquadrarlo
... Several interactions between glucocorticoid and pituitary-thyroid axis have been reported It is suggested that the physiological concentration of glucocorticoid has a suppressive effect on TSH secretion Glucocorticoid deficiency may be one of the causes of the increase in TSH ...
... Several interactions between glucocorticoid and pituitary-thyroid axis have been reported It is suggested that the physiological concentration of glucocorticoid has a suppressive effect on TSH secretion Glucocorticoid deficiency may be one of the causes of the increase in TSH ...
Actions of thyroid hormones in bone
... receptor a (TRa). T3 exerts anabolic actions during growth to stimulate peak bone mass acrrual, but has catabolic effects on the adult skeleton that increase bone turnover. Recent studies have also suggested that TSH may have direct actions in bone cells, but such effects are difficult to resolve in ...
... receptor a (TRa). T3 exerts anabolic actions during growth to stimulate peak bone mass acrrual, but has catabolic effects on the adult skeleton that increase bone turnover. Recent studies have also suggested that TSH may have direct actions in bone cells, but such effects are difficult to resolve in ...
description and initial evaluation of a xenopus metamorphosis assay
... metamorphosis assay (XEMA) was developed specifically to address ED effects on the thyroid system. During test development, special emphasis was placed on the ability of the test protocol to detect sensitively both antithyroidal and thyromimetic activities of test compounds. Furthermore, attention w ...
... metamorphosis assay (XEMA) was developed specifically to address ED effects on the thyroid system. During test development, special emphasis was placed on the ability of the test protocol to detect sensitively both antithyroidal and thyromimetic activities of test compounds. Furthermore, attention w ...
An Endoplasmic Reticulum Storage Disease Causing Congenital
... For each tissue preparation, samples were incubated for 30 min at 37°C in DME lacking methionine and cysteine. The tissue was then labeled for up to 30 min with [35S]amino acids (Expre35S35S, New England Nuclear, Boston, MA) for the times stated, and chased in the presence of excess unlabeled methio ...
... For each tissue preparation, samples were incubated for 30 min at 37°C in DME lacking methionine and cysteine. The tissue was then labeled for up to 30 min with [35S]amino acids (Expre35S35S, New England Nuclear, Boston, MA) for the times stated, and chased in the presence of excess unlabeled methio ...
Pregnant rat uterus expresses high levels of the type 3
... any measurable extent suggests that the uterus may also play an important role in regulating thyroid hormone access to the developing fetus either before placental function, which begins in the rat on gestational day 11 (E11) (14), or during the later stages of pregnancy. The present study was carri ...
... any measurable extent suggests that the uterus may also play an important role in regulating thyroid hormone access to the developing fetus either before placental function, which begins in the rat on gestational day 11 (E11) (14), or during the later stages of pregnancy. The present study was carri ...
‘ii?
... metabolic processesare affected, causing numerous clinical manifestations such as fatigue, lethargy, cold intolerance, dry skin, bradycardia, and hoarseness.3Low levels of thyroxine also causean increase in the serum levels of thyroid stimulating hormone (TSH) (also called thyrotropin). Measurement ...
... metabolic processesare affected, causing numerous clinical manifestations such as fatigue, lethargy, cold intolerance, dry skin, bradycardia, and hoarseness.3Low levels of thyroxine also causean increase in the serum levels of thyroid stimulating hormone (TSH) (also called thyrotropin). Measurement ...
Article PDF
... environmental poisons, but one whose properties make it a valuable industrial metal. Lead has long been known to affect the neurological, renal, and reproductive systems.1 Scientific understanding of lead toxicity in other organ systems and at low levels of exposure continues to evolve.2 The two pri ...
... environmental poisons, but one whose properties make it a valuable industrial metal. Lead has long been known to affect the neurological, renal, and reproductive systems.1 Scientific understanding of lead toxicity in other organ systems and at low levels of exposure continues to evolve.2 The two pri ...
Subclinical Hypothyroidism: When to Treat, When to
... of thyroxine treatment, which resulted in mean serum TSH concentrations of 2.8, 1.0, and 0.3 mIU/L, respectively. There were no differences in hypothyroid symptoms among the groups, and patients could not distinguish among the 3 levels of thyroid hormone replacement.50 Placebos have a significant ef ...
... of thyroxine treatment, which resulted in mean serum TSH concentrations of 2.8, 1.0, and 0.3 mIU/L, respectively. There were no differences in hypothyroid symptoms among the groups, and patients could not distinguish among the 3 levels of thyroid hormone replacement.50 Placebos have a significant ef ...
Recurring Acute Abdomen, Ovarian Cyst
... removed. At that time thyroid dysfunction was neither suspected nor investigated. Five years later patient again developed acute abdomen with a large cyst in the remaining left ovary. Thyroid evaluation at this point of time indicated profound hypothyroidism. Treatment with thyroxin resulted in mark ...
... removed. At that time thyroid dysfunction was neither suspected nor investigated. Five years later patient again developed acute abdomen with a large cyst in the remaining left ovary. Thyroid evaluation at this point of time indicated profound hypothyroidism. Treatment with thyroxin resulted in mark ...
An Oculist Looks at Endocrine Exophthalmos
... you take the average ages you are not getting much help, for the average ages of the women with toxic eye signs is fifty and of those with pituitary eye signs forty-five years; though you do not need me to remind you of the dangers attached to the taking of averages when there are only small numbers ...
... you take the average ages you are not getting much help, for the average ages of the women with toxic eye signs is fifty and of those with pituitary eye signs forty-five years; though you do not need me to remind you of the dangers attached to the taking of averages when there are only small numbers ...
O A
... group B (32-36 weeks) and group C; control( ≥ 37) weeks. The mean gestational age, birth weight and other clinical data were determined for each group. Results:In test (1), our results showed significantly lower plasma concentrations of T4 and TSH in premature than in term babies while in test (2), ...
... group B (32-36 weeks) and group C; control( ≥ 37) weeks. The mean gestational age, birth weight and other clinical data were determined for each group. Results:In test (1), our results showed significantly lower plasma concentrations of T4 and TSH in premature than in term babies while in test (2), ...
379 - FTP
... gases. It is a by-product of many industrial processes. Trace amounts of dissolved H2S are found in wastewaters in equilibrium with dissolved sulfides and hydrosulfides. It also is found in volcanic eruptions, hot springs and in troposphere. The average concentration of H2S in the air is about 0.05 ...
... gases. It is a by-product of many industrial processes. Trace amounts of dissolved H2S are found in wastewaters in equilibrium with dissolved sulfides and hydrosulfides. It also is found in volcanic eruptions, hot springs and in troposphere. The average concentration of H2S in the air is about 0.05 ...
Maquetación 1 - Histology and Histopathology
... growth processes of the thyroid gland (Lewinski and Karbownik, 2002). Melatonin production is catalyzed by two well-characterized enzymatic reactions from tryptophan. First, serotonin is converted to Nacetylserotonin (NAS) by the enzyme arylalkylamine Nacetyltransferase (AANAT) (Voisin et al., 1984) ...
... growth processes of the thyroid gland (Lewinski and Karbownik, 2002). Melatonin production is catalyzed by two well-characterized enzymatic reactions from tryptophan. First, serotonin is converted to Nacetylserotonin (NAS) by the enzyme arylalkylamine Nacetyltransferase (AANAT) (Voisin et al., 1984) ...
A Case of Thyrotropin-Secreting Pituitary Adenoma (TSH-oma)
... for the next 3h. After 24-h sc injection of octerotide three times daily (300 µ/day), serum TSH concentration decreased dramatically (65%). The octreotide test is useful before surgery to predict whether the drug could be used as therapy if surgery alone was not curative. The different response is d ...
... for the next 3h. After 24-h sc injection of octerotide three times daily (300 µ/day), serum TSH concentration decreased dramatically (65%). The octreotide test is useful before surgery to predict whether the drug could be used as therapy if surgery alone was not curative. The different response is d ...
Thyroid hormones as molecular determinants of thermogenesis
... 1999). These short- and long-term effects have often been taken to reflect the extranuclear- and nuclearmediated actions of T3, respectively. However, simply looking at the latency of a response to T3 may not necessarily allow us to discriminate nuclear-mediated effects from extranuclear-mediated on ...
... 1999). These short- and long-term effects have often been taken to reflect the extranuclear- and nuclearmediated actions of T3, respectively. However, simply looking at the latency of a response to T3 may not necessarily allow us to discriminate nuclear-mediated effects from extranuclear-mediated on ...
Primary Paraganglioma of the Parathyroid: A Case Report and
... area was not attached to the thyroid gland. The left superior parathyroid gland was visualized and was interpreted to be normal. The lobe of the thyroid was removed without incident. The superior mediastinal mass was removed intact by blunt dissection. The specimen had two parts. The 3 9 2.1 9 0.8 c ...
... area was not attached to the thyroid gland. The left superior parathyroid gland was visualized and was interpreted to be normal. The lobe of the thyroid was removed without incident. The superior mediastinal mass was removed intact by blunt dissection. The specimen had two parts. The 3 9 2.1 9 0.8 c ...
Iodine-131
Iodine-131 (131I), also loosely and nonspecifically called radioiodine, is an important radioisotope of iodine discovered by Glenn Seaborg and John Livingood in 1938 at the University of California, Berkeley. It has a radioactive decay half-life of about eight days. It is associated with nuclear energy, medical diagnostic and treatment procedures, and natural gas production. It also plays a major role as a radioactive isotope present in nuclear fission products, and was a significant contributor to the health hazards from open-air atomic bomb testing in the 1950s, and from the Chernobyl disaster, as well as being a large fraction of the contamination hazard in the first weeks in the Fukushima nuclear crisis. This is because I-131 is a major uranium, plutonium fission product, comprising nearly 3% of the total products of fission (by weight). See fission product yield for a comparison with other radioactive fission products. I-131 is also a major fission product of uranium-233, produced from thorium.Due to its mode of beta decay, iodine-131 is notable for causing mutation and death in cells that it penetrates, and other cells up to several millimeters away. For this reason, high doses of the isotope are sometimes less dangerous than low doses, since they tend to kill thyroid tissues that would otherwise become cancerous as a result of the radiation. For example, children treated with moderate dose of I-131 for thyroid adenomas had a detectable increase in thyroid cancer, but children treated with a much higher dose did not. Likewise, most studies of very-high-dose I-131 for treatment of Graves disease have failed to find any increase in thyroid cancer, even though there is linear increase in thyroid cancer risk with I-131 absorption at moderate doses. Thus, iodine-131 is increasingly less employed in small doses in medical use (especially in children), but increasingly is used only in large and maximal treatment doses, as a way of killing targeted tissues. This is known as ""therapeutic use.""Iodine-131 can be ""seen"" by nuclear medicine imaging techniques (i.e., gamma cameras) whenever it is given for therapeutic use, since about 10% of its energy and radiation dose is via gamma radiation. However, since the other 90% of radiation (beta radiation) causes tissue damage without contributing to any ability to see or ""image"" the isotope, other less-damaging radioisotopes of iodine such as iodine-123 (see isotopes of iodine) are preferred in situations when only nuclear imaging is required. The isotope I-131 is still occasionally used for purely diagnostic (i.e., imaging) work, due to its low expense compared to other iodine radioisotopes. Very small medical imaging doses of I-131 have not shown any increase in thyroid cancer. The low-cost availability of I-131, in turn, is due to the relative ease of creating I-131 by neutron bombardment of natural tellurium in a nuclear reactor, then separating I-131 out by various simple methods (i.e., heating to drive off the volatile iodine). By contrast, other iodine radioisotopes are usually created by far more expensive techniques, starting with reactor radiation of expensive capsules of pressurized xenon gas.Iodine-131 is also one of the most commonly used gamma-emitting radioactive industrial tracer. Radioactive tracer isotopes are injected with hydraulic fracturing fluid to determine the injection profile and location of fractures created by hydraulic fracturing.Much smaller incidental doses of iodine-131 than those used in medical therapeutic procedures, are thought to be the major cause of increased thyroid cancers after accidental nuclear contamination. These cancers happen from residual tissue radiation damage caused by the I-131, and usually appear years after exposure, long after the I-131 has decayed.