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Genetics of Stroke
Genetics of Stroke

... several tens of thousands of years more generations of shuffling than whites ...
DNA Sequencing and Gene Analysis
DNA Sequencing and Gene Analysis

... Recently a number of faster and cheaper sequencing methods have been developed. – The Archon X prize (2006): "the first Team that can build a device and use it to sequence 100 human genomes within 10 days or less, with an accuracy of no more than one error in every 100,000 bases sequenced, with sequ ...
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... best‐hit (%BBH) genes at its core. We have developed a JavaScript‐based tool  (http://lycofs01.lycoming.edu/~newman/rosa/) that calculates AAI, %BBH, and ROSA using the  output from the “Sequence‐based comparison” tool on the Rapid Annotation with Subsystems  Technology (RAST) service (rast.nmpdr.or ...
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Site Directed Nucleases (SDN) for targeted

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Whole genome sequencing



Whole genome sequencing (also known as full genome sequencing, complete genome sequencing, or entire genome sequencing) is a laboratory process that determines the complete DNA sequence of an organism's genome at a single time. This entails sequencing all of an organism's chromosomal DNA as well as DNA contained in the mitochondria and, for plants, in the chloroplast.Whole genome sequencing should not be confused with DNA profiling, which only determines the likelihood that genetic material came from a particular individual or group, and does not contain additional information on genetic relationships, origin or susceptibility to specific diseases. Also unlike full genome sequencing, SNP genotyping covers less than 0.1% of the genome. Almost all truly complete genomes are of microbes; the term ""full genome"" is thus sometimes used loosely to mean ""greater than 95%"". The remainder of this article focuses on nearly complete human genomes.High-throughput genome sequencing technologies have largely been used as a research tool and are currently being introduced in the clinics. In the future of personalized medicine, whole genome sequence data will be an important tool to guide therapeutic intervention. The tool of gene sequencing at SNP level is also used to pinpoint functional variants from association studies and improve the knowledge available to researchers interested in evolutionary biology, and hence may lay the foundation for predicting disease susceptibility and drug response.
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