D. melanogaster - GEP Community Server
... Based on RNA-Seq data from either the same or closely-related species D. simulans, D. yakuba, D. erecta, D. ananassae, D. pseudoobscura, D. willistoni, D. virilis, and D. mojavensis Predictions include untranslated regions and multiple isoforms Records not yet available through the NCBI RefSeq datab ...
... Based on RNA-Seq data from either the same or closely-related species D. simulans, D. yakuba, D. erecta, D. ananassae, D. pseudoobscura, D. willistoni, D. virilis, and D. mojavensis Predictions include untranslated regions and multiple isoforms Records not yet available through the NCBI RefSeq datab ...
Nucleic Acids Research, 32: D489-D492 (2004).
... that Alu subfamilies have originated through successive waves of ®xation from sequential small subsets of active Alu sequences. The oldest Alu-related elements are the monomeric FAM, FRAM and FLAM sequences. The oldest Alu dimeric subfamilies are Alu-Jo and Alu-Jb, estimated to be ~80 million years ...
... that Alu subfamilies have originated through successive waves of ®xation from sequential small subsets of active Alu sequences. The oldest Alu-related elements are the monomeric FAM, FRAM and FLAM sequences. The oldest Alu dimeric subfamilies are Alu-Jo and Alu-Jb, estimated to be ~80 million years ...
Genome-wide characteristics of sequence coverage by next
... “The most likely explanation for why genes for common diseases have not been found is that, with few exceptions, they do not exist. …., if inherited genes are not to blame for our commonest illnesses, can we find out what is? “ ...
... “The most likely explanation for why genes for common diseases have not been found is that, with few exceptions, they do not exist. …., if inherited genes are not to blame for our commonest illnesses, can we find out what is? “ ...
1 THE EVOLUTION OF LINE-1 IN VERTEBRATES Stéphane
... probably one of the genomic features that show the most variation in this group. At one end of the spectrum, mammalian genomes host an extremely large number of L1 insertions that have accumulated since the origin of mammals and account for close to 20% of their mass (Lander et al. 2001; Mouse Genom ...
... probably one of the genomic features that show the most variation in this group. At one end of the spectrum, mammalian genomes host an extremely large number of L1 insertions that have accumulated since the origin of mammals and account for close to 20% of their mass (Lander et al. 2001; Mouse Genom ...
An accessible database for mouse and human whole transcriptome
... Its main advantage is that it has a large dynamic range and requires only basic sample preparation steps (reverse transcription of RNA). Double-stranded DNA dye (such as SYBR) based qPCR quantifies the amount of double-stranded DNA in a sample. A pair of specific primers amplifies a short (usually 6 ...
... Its main advantage is that it has a large dynamic range and requires only basic sample preparation steps (reverse transcription of RNA). Double-stranded DNA dye (such as SYBR) based qPCR quantifies the amount of double-stranded DNA in a sample. A pair of specific primers amplifies a short (usually 6 ...
PDF
... in iron cycling [7, 13, 17]. Apparently, “Ferrovum”-related iron oxidisers prefer higher pH values and ferrous iron concentrations than the well-studied A. ferrooxidans [15]. The comparison of the microbial composition of the AMD springs Lower and Upper Red Eyes in the Appalachian Mountains (Pennsyl ...
... in iron cycling [7, 13, 17]. Apparently, “Ferrovum”-related iron oxidisers prefer higher pH values and ferrous iron concentrations than the well-studied A. ferrooxidans [15]. The comparison of the microbial composition of the AMD springs Lower and Upper Red Eyes in the Appalachian Mountains (Pennsyl ...
- LSHTM Research Online
... vaccine. B. pseudomallei is listed as a tier 1 select agent, and as current therapeutic options are limited due to its natural resistance to most antibiotics, the development of new antimicrobial therapies is imperative. To identify drug targets and better understand the complex B. pseudomallei geno ...
... vaccine. B. pseudomallei is listed as a tier 1 select agent, and as current therapeutic options are limited due to its natural resistance to most antibiotics, the development of new antimicrobial therapies is imperative. To identify drug targets and better understand the complex B. pseudomallei geno ...
A viability-linked metagenomic analysis of
... Background: Recent studies posit a reciprocal dependency between the microbiomes associated with humans and indoor environments. However, none of these metagenome surveys has considered the viability of constituent microorganisms when inferring impact on human health. Results: Reported here are the ...
... Background: Recent studies posit a reciprocal dependency between the microbiomes associated with humans and indoor environments. However, none of these metagenome surveys has considered the viability of constituent microorganisms when inferring impact on human health. Results: Reported here are the ...
Evolutionary origin and consequences of uniparental mitochondrial
... form extremely ancient asexual lineages (the animal mitochondrial lineage must be > 1 billion years old). An intriguing question is how non-recombining mitochondria have survived for so long and apparently managed to escape too severe an accumulation of mutations. Asexual reproduction is basically a ...
... form extremely ancient asexual lineages (the animal mitochondrial lineage must be > 1 billion years old). An intriguing question is how non-recombining mitochondria have survived for so long and apparently managed to escape too severe an accumulation of mutations. Asexual reproduction is basically a ...
The genomic landscape of meiotic crossovers and gene
... Sequencing and genotyping of meiotic tetrads We constructed F1 hybrids of the A. thaliana accessions Columbia (Col) and Landsberg erecta (Ler) in the quartet1 (qrt1) −/− background (Preuss et al., 1994) and crossed individual pollen tetrads to a male sterile EMS mutant of the Cape Verde Island (Cvi) ...
... Sequencing and genotyping of meiotic tetrads We constructed F1 hybrids of the A. thaliana accessions Columbia (Col) and Landsberg erecta (Ler) in the quartet1 (qrt1) −/− background (Preuss et al., 1994) and crossed individual pollen tetrads to a male sterile EMS mutant of the Cape Verde Island (Cvi) ...
- Wiley Online Library
... (Fig. 1c) and six contained one or more large (> 50 amino acid) insertions; these same features were also observed in the corresponding P. capuana genomic sequences. One of the most extreme examples of genetic degeneration within the P. capuana carotenoid pathway is the transcript representing LCYB: ...
... (Fig. 1c) and six contained one or more large (> 50 amino acid) insertions; these same features were also observed in the corresponding P. capuana genomic sequences. One of the most extreme examples of genetic degeneration within the P. capuana carotenoid pathway is the transcript representing LCYB: ...
Diversity of Lactase Persistence Alleles in Ethiopia
... expression of the lactase gene LCT is responsible for lactase persistence and appears to have been under strong directional selection in the last 5,000 years, evidenced by the widespread occurrence of this allele on an extended haplotype. In Africa and the Middle East, the situation is more complica ...
... expression of the lactase gene LCT is responsible for lactase persistence and appears to have been under strong directional selection in the last 5,000 years, evidenced by the widespread occurrence of this allele on an extended haplotype. In Africa and the Middle East, the situation is more complica ...
Pourcel et al., Microbiology 2005
... elements present in the CO92 Y. pestis genome are shown in Fig. 2(a). The same 28 bp repeated sequence is found interspaced with spacers, 32 or 33 bp in length, in all three elements. They start with a truncated (19 bp for YP1 but 22 bp for YP2) repeat and end with a perfect 28 bp repeat, followed b ...
... elements present in the CO92 Y. pestis genome are shown in Fig. 2(a). The same 28 bp repeated sequence is found interspaced with spacers, 32 or 33 bp in length, in all three elements. They start with a truncated (19 bp for YP1 but 22 bp for YP2) repeat and end with a perfect 28 bp repeat, followed b ...
Query Results
... Currently, only the pair NlaIII-BsmFI is available. In the near future, other enzyme pairs such as the one used in Long-SAGE will be added. ...
... Currently, only the pair NlaIII-BsmFI is available. In the near future, other enzyme pairs such as the one used in Long-SAGE will be added. ...
The biased nucleotide composition of the HIV genome: a constant
... O (35%, Table 1). Group N and P viruses appear to contain slightly higher (group N) or lower (group P) levels of A-nucleotides, but only one (group P) or no (group N) full-length genomes with long terminal repeats (LTRs) are available for these groups (Table 1). As the LTR is relatively A-poor [5], ...
... O (35%, Table 1). Group N and P viruses appear to contain slightly higher (group N) or lower (group P) levels of A-nucleotides, but only one (group P) or no (group N) full-length genomes with long terminal repeats (LTRs) are available for these groups (Table 1). As the LTR is relatively A-poor [5], ...
PPTX - Tandy Warnow
... • MetaPhyler, MetaPhlAn, and mOTU are marker-based techniques (but use different marker genes). ...
... • MetaPhyler, MetaPhlAn, and mOTU are marker-based techniques (but use different marker genes). ...
(base) sequence of the genome might reflect biological information
... (ProQuest: ... denotes formulae omitted.) 1. INTRODUCTION It was well known that there were structural hierarchies in the genome, such as the chromosome, nucleosome, ORF (open reading frame) and so on [1]. Among them, much attention have been paid to the ORF, and many research projects were being pe ...
... (ProQuest: ... denotes formulae omitted.) 1. INTRODUCTION It was well known that there were structural hierarchies in the genome, such as the chromosome, nucleosome, ORF (open reading frame) and so on [1]. Among them, much attention have been paid to the ORF, and many research projects were being pe ...
Bioethics Thesaurus for Genetics
... A proposed technological approach to obtain human pluripotent stem cells, which are the functional equivalent of human embryonic stem cells, without creating or destroying human embryos (ANT website, accessed 1/26/10). The process was originally proposed by William B. Hurlbut BT Nuclear transfer tec ...
... A proposed technological approach to obtain human pluripotent stem cells, which are the functional equivalent of human embryonic stem cells, without creating or destroying human embryos (ANT website, accessed 1/26/10). The process was originally proposed by William B. Hurlbut BT Nuclear transfer tec ...
ppt - Chair of Computational Biology
... conserved, reciprocally unique landmarks were detected within the mouse and human genomes, which can be joined into conserved syntenic segments and blocks. A typical 510-kb segment of mouse chromosome 12 that shares common ancestry with a 600-kb section of human chromosome 14 is shown. Blue lines co ...
... conserved, reciprocally unique landmarks were detected within the mouse and human genomes, which can be joined into conserved syntenic segments and blocks. A typical 510-kb segment of mouse chromosome 12 that shares common ancestry with a 600-kb section of human chromosome 14 is shown. Blue lines co ...
induction of instability at selected loci in maize
... 1:1 ratio will occur if the plant is homozygous for the mutation 1/2 of the gametes possess Ac and 1/2 will possess the mutation. The Ds in the cells possessing Ac can subsequently "jump out" creating variegation in the plants arising from this cross. The other half will posses the mutated a1m‐4 loc ...
... 1:1 ratio will occur if the plant is homozygous for the mutation 1/2 of the gametes possess Ac and 1/2 will possess the mutation. The Ds in the cells possessing Ac can subsequently "jump out" creating variegation in the plants arising from this cross. The other half will posses the mutated a1m‐4 loc ...
Patterns of Segmental Duplication in the Human Genome
... and 10.7% for Ensembl genes. Both values are significantly higher than expected under the neutral-duplication model (for known genes: P value ¼ 0.02; for Ensembl genes: P value 2.2e216. [see, e.g., figure 3]). Second, the two types of duplications show a striking difference in size distribution (f ...
... and 10.7% for Ensembl genes. Both values are significantly higher than expected under the neutral-duplication model (for known genes: P value ¼ 0.02; for Ensembl genes: P value 2.2e216. [see, e.g., figure 3]). Second, the two types of duplications show a striking difference in size distribution (f ...
Complete genome sequence of the thermophilic Thermus sp
... scotoductus SA-01) were selected for the comparison. The genome of strain HB27 consists of a chromosome (1.89 Mb) and a megaplasmid (0.23 Mb). On the other hand, strain HB8 has a chromosome of 1.85 Mb, a megaplasmid (0.26 Mb) and a plasmid (9.3 kb) [5]. The genome of T. scotoductus includes a 2.3 Mb ...
... scotoductus SA-01) were selected for the comparison. The genome of strain HB27 consists of a chromosome (1.89 Mb) and a megaplasmid (0.23 Mb). On the other hand, strain HB8 has a chromosome of 1.85 Mb, a megaplasmid (0.26 Mb) and a plasmid (9.3 kb) [5]. The genome of T. scotoductus includes a 2.3 Mb ...
2 - cellbiochem.ca
... • Antibiotic resistance gene: allow for selection for bacterial cells that have taken up the vector ...
... • Antibiotic resistance gene: allow for selection for bacterial cells that have taken up the vector ...
Whole genome sequencing
Whole genome sequencing (also known as full genome sequencing, complete genome sequencing, or entire genome sequencing) is a laboratory process that determines the complete DNA sequence of an organism's genome at a single time. This entails sequencing all of an organism's chromosomal DNA as well as DNA contained in the mitochondria and, for plants, in the chloroplast.Whole genome sequencing should not be confused with DNA profiling, which only determines the likelihood that genetic material came from a particular individual or group, and does not contain additional information on genetic relationships, origin or susceptibility to specific diseases. Also unlike full genome sequencing, SNP genotyping covers less than 0.1% of the genome. Almost all truly complete genomes are of microbes; the term ""full genome"" is thus sometimes used loosely to mean ""greater than 95%"". The remainder of this article focuses on nearly complete human genomes.High-throughput genome sequencing technologies have largely been used as a research tool and are currently being introduced in the clinics. In the future of personalized medicine, whole genome sequence data will be an important tool to guide therapeutic intervention. The tool of gene sequencing at SNP level is also used to pinpoint functional variants from association studies and improve the knowledge available to researchers interested in evolutionary biology, and hence may lay the foundation for predicting disease susceptibility and drug response.