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13-Biotechbasics-website - kyoussef-mci
13-Biotechbasics-website - kyoussef-mci

... a colony. Colonies with nonrecombinant plasmids will be blue, because they can hydrolyze X-gal. Colonies with recombinant plasmids, in which lacZ is disrupted, will be white, because they cannot hydrolyze X-gal. By screening the white colonies with a nucleic acid probe (see Figure 20.5), researchers ...
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DNA Sample Collection from Animal Companions General Shipping

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Notes - marric.us

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Notes - The University of Sydney
Notes - The University of Sydney

... produced by certain species of bacteria to restrict bacteriophage DNA. Bacteriophage are viruses that infect bacteria. The bacteria produce the enzymes to prevent the infection. They protect their own DNA by methylation. The most relevant restriction enzymes for molecular biology are type II, which ...
DNA Profiling - Miss Jan`s Science Wikispace
DNA Profiling - Miss Jan`s Science Wikispace

... same restriction enzyme must be used to cut both the gene and the plasmid as this will produce the same sticky ends that can then be joined together by DNA ligase.. HOW – Use of specific restriction enzymes has enabled the cutting of DNA at a recognition site specific to that enzyme. For example the ...
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Name: Date: Genetic Engineering Notes Selective Breeding: People

...  Transformation – when a cell takes DNA from outside the cell and integrates it into the cell’s own DNA  This can be done three ways • Natural uptake of DNA from surroundings • Injection with a needle • Using a virus to inject the DNA Bacteria:  Some bacteria are able to naturally able to pick up ...
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theme one - Essentials Education
theme one - Essentials Education

... in the nucleus of eukaryotic cells and are visible as the cells start to divide. The chromosome number is constant for each species, e.g. 46 in humans, 48 in a chimpanzee, 40 in a mouse and 38 in cabbage. Chromosomes in nondividing cells are single stranded and the DNA is not condensed, that is, the ...
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Molecular cloning



Molecular cloning is a set of experimental methods in molecular biology that are used to assemble recombinant DNA molecules and to direct their replication within host organisms. The use of the word cloning refers to the fact that the method involves the replication of one molecule to produce a population of cells with identical DNA molecules. Molecular cloning generally uses DNA sequences from two different organisms: the species that is the source of the DNA to be cloned, and the species that will serve as the living host for replication of the recombinant DNA. Molecular cloning methods are central to many contemporary areas of modern biology and medicine.In a conventional molecular cloning experiment, the DNA to be cloned is obtained from an organism of interest, then treated with enzymes in the test tube to generate smaller DNA fragments. Subsequently, these fragments are then combined with vector DNA to generate recombinant DNA molecules. The recombinant DNA is then introduced into a host organism (typically an easy-to-grow, benign, laboratory strain of E. coli bacteria). This will generate a population of organisms in which recombinant DNA molecules are replicated along with the host DNA. Because they contain foreign DNA fragments, these are transgenic or genetically modified microorganisms (GMO). This process takes advantage of the fact that a single bacterial cell can be induced to take up and replicate a single recombinant DNA molecule. This single cell can then be expanded exponentially to generate a large amount of bacteria, each of which contain copies of the original recombinant molecule. Thus, both the resulting bacterial population, and the recombinant DNA molecule, are commonly referred to as ""clones"". Strictly speaking, recombinant DNA refers to DNA molecules, while molecular cloning refers to the experimental methods used to assemble them.
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