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Chapter 11 Fundamentals of Nervous System
Chapter 11 Fundamentals of Nervous System

... Repolarization – the membrane returns to its resting membrane potential Hyperpolarization – the inside of the membrane becomes more negative than the resting potential ...
Endocrinology – general, hypothalamus, pituitary
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PDF

... the amount of silver impregnation and staining intensity for cresyl violet. The central portions of our tissue blocks, which were exposed to the least mordant and silver nitrate demonstrated the most robust Nissl staining. The superficial areas, with good silver stain, had faint cresyl violet staini ...
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No Slide Title

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Neurobiology of injury to the developing brain.

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... Simula et al. (2001) have revealed that the number of neurons associated with the possum SO is significantly higher within the distal region (duodenal end) of the sphincter than in the more proximal part. Furthermore, they found that approximately (approx.) 50% of all SO associated nerve cells were ...
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... plaques. The demonstration of herpes viruses, in particular herpes I, II, and VI, in a significant proportion of MS plaques over the past decade (12,13), evidence that the anti-herpes drug acyclovir will reduce the number of attacks of MS (14), and, more recently, evidence for chlamydial infection ( ...
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... each of the brain's two hemispheres the overlying cortex is divided into four anatomically distinct lobes: frontal, parietal, temporal, and occipital (see Figure 12B), originally named for the skull bones that encase them. These lobes have specialized functions. The frontal lobe is largely concerned ...
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What Are the Units of Brain Function?

... the cell body is increased immensely by extensions of the cell membrane into dendrites. The dendritic area is further increased by many small protrusions called dendritic spines. A neuron may have from 1 to 20 dendrites, each of which may have from one to many branches, and the spines on the branche ...
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Neuroregeneration

Neuroregeneration refers to the regrowth or repair of nervous tissues, cells or cell products. Such mechanisms may include generation of new neurons, glia, axons, myelin, or synapses. Neuroregeneration differs between the peripheral nervous system (PNS) and the central nervous system (CNS) by the functional mechanisms and especially the extent and speed. When an axon is damaged, the distal segment undergoes Wallerian degeneration, losing its myelin sheath. The proximal segment can either die by apoptosis or undergo the chromatolytic reaction, which is an attempt at repair. In the CNS, synaptic stripping occurs as glial foot processes invade the dead synapse.Nervous system injuries affect over 90,000 people every year. It is estimated that spinal cord injuries alone affect 10,000 each year. As a result of this high incidence of neurological injuries, nerve regeneration and repair, a subfield of neural tissue engineering, is becoming a rapidly growing field dedicated to the discovery of new ways to recover nerve functionality after injury. The nervous system is divided into two parts: the central nervous system, which consists of the brain and spinal cord, and the peripheral nervous system, which consists of cranial and spinal nerves along with their associated ganglia. While the peripheral nervous system has an intrinsic ability for repair and regeneration, the central nervous system is, for the most part, incapable of self-repair and regeneration. There is currently no treatment for recovering human nerve function after injury to the central nervous system. In addition, multiple attempts at nerve re-growth across the PNS-CNS transition have not been successful. There is simply not enough knowledge about regeneration in the central nervous system. In addition, although the peripheral nervous system has the capability for regeneration, much research still needs to be done to optimize the environment for maximum regrowth potential. Neuroregeneration is important clinically, as it is part of the pathogenesis of many diseases, including multiple sclerosis.
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