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CURRICULUM VITAE - Boston Retinal Implant Project
CURRICULUM VITAE - Boston Retinal Implant Project

... differentiation, growth, and regeneration in the mammalian central nervous system (CNS). Elucidating the mechanisms regulating these processes is not only fundamental for our understanding of neural development, but also it may provide crucial information for the development of therapeutic strategie ...
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Chapter 14 The Autonomic Nervous System Chapter - CM
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... neurons. Postganglionic axons then transmit action potentials to the target cell. ACh is one of three neurotransmitters that can be released in the synapse with target cells. b. Norepinephrine (noradrenalin) is the most frequently utilized neurotransmitter released into the synapses between axons an ...
Neural Development - inst.eecs.berkeley.edu
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... After the ectodermal tissue has acquired its neural fate, another series of signaling interactions determine the type of neural cell to which it gives rise. The mature nervous system contains a vast array of cell types, which can be divided into two main categories:  the neurons, primarily responsi ...
PowerLecture: Chapter 13
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ANPS 019 Black 12-05
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... - In some parts of the spinal cord the gray matter has another horn called lateral horn or intermediolateral horn where the mother cells of sympathetic nerves are found. - In the ventral horn of gray matter there are the cell bodies of motor neurons .Aα nerve fibers of these motor nerves supplies th ...
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The Nervous System

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Chapter 1 A Perspective on Human Genetics

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Central Auditory Pathways

... Communication between neurons is achieved by the release of small packets of neurotransmitters into the synapse If the release of neurotransmitters reaches a critical level to the receiving neuron, it will cause an action potential to be generated in the cell body “All-or-none” behavior ...
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Neuroregeneration

Neuroregeneration refers to the regrowth or repair of nervous tissues, cells or cell products. Such mechanisms may include generation of new neurons, glia, axons, myelin, or synapses. Neuroregeneration differs between the peripheral nervous system (PNS) and the central nervous system (CNS) by the functional mechanisms and especially the extent and speed. When an axon is damaged, the distal segment undergoes Wallerian degeneration, losing its myelin sheath. The proximal segment can either die by apoptosis or undergo the chromatolytic reaction, which is an attempt at repair. In the CNS, synaptic stripping occurs as glial foot processes invade the dead synapse.Nervous system injuries affect over 90,000 people every year. It is estimated that spinal cord injuries alone affect 10,000 each year. As a result of this high incidence of neurological injuries, nerve regeneration and repair, a subfield of neural tissue engineering, is becoming a rapidly growing field dedicated to the discovery of new ways to recover nerve functionality after injury. The nervous system is divided into two parts: the central nervous system, which consists of the brain and spinal cord, and the peripheral nervous system, which consists of cranial and spinal nerves along with their associated ganglia. While the peripheral nervous system has an intrinsic ability for repair and regeneration, the central nervous system is, for the most part, incapable of self-repair and regeneration. There is currently no treatment for recovering human nerve function after injury to the central nervous system. In addition, multiple attempts at nerve re-growth across the PNS-CNS transition have not been successful. There is simply not enough knowledge about regeneration in the central nervous system. In addition, although the peripheral nervous system has the capability for regeneration, much research still needs to be done to optimize the environment for maximum regrowth potential. Neuroregeneration is important clinically, as it is part of the pathogenesis of many diseases, including multiple sclerosis.
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