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Ch 28 CNS Money [5-11
Ch 28 CNS Money [5-11

... - Lafora bodies in cytoplasm of neurons in myoclonic epilepsy Reactions of other glial cells to injury - oligodendrocytes & ependymal cells not in active response to CNS injury - oligodendroglial cells o injury/apoptosis is feature of acquired demyelinating disorders & leukodystrophies o glial cytop ...
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...  The two hemispheres are connected by a band of neural fibers called the corpus callosum, which allows each side to communicate with the other.  The occipital lobe is located in the rear base and processes information from the eyes.  The parietal lobe is located at the top and back and processes ...
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Substrate Micropatterning as a New in Vitro Cell Culture System to

... Considering this promising data, we then investigated if DRG-derived neurites growing on highly restrictive substrates could reproduce the two myelination paradigms that comprise myelin research: CNS myelination by oligodendrocytes and PNS myelination by Schwann cells. To model CNS myelination in vi ...
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... Abstract. Cryotherapy (ice application) and deep cryosurgery are commonly employed for neurological, surgical, and physical therapy. Prolonged and repetitive cryotherapy can result in permanent damage to myelinated nerves which are susceptible to myelin coagulation, axonal destruction, and focal som ...
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The mechanical control of nervous system development

... have seen only little progress in this field when compared to other (e.g. electrophysiology, molecular biology, or genetics-based) areas of neuroscience. Progress often depends on the availability of appropriate methodology. Only recently has the increasing involvement of physical and engineering ap ...
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Neuroregeneration

Neuroregeneration refers to the regrowth or repair of nervous tissues, cells or cell products. Such mechanisms may include generation of new neurons, glia, axons, myelin, or synapses. Neuroregeneration differs between the peripheral nervous system (PNS) and the central nervous system (CNS) by the functional mechanisms and especially the extent and speed. When an axon is damaged, the distal segment undergoes Wallerian degeneration, losing its myelin sheath. The proximal segment can either die by apoptosis or undergo the chromatolytic reaction, which is an attempt at repair. In the CNS, synaptic stripping occurs as glial foot processes invade the dead synapse.Nervous system injuries affect over 90,000 people every year. It is estimated that spinal cord injuries alone affect 10,000 each year. As a result of this high incidence of neurological injuries, nerve regeneration and repair, a subfield of neural tissue engineering, is becoming a rapidly growing field dedicated to the discovery of new ways to recover nerve functionality after injury. The nervous system is divided into two parts: the central nervous system, which consists of the brain and spinal cord, and the peripheral nervous system, which consists of cranial and spinal nerves along with their associated ganglia. While the peripheral nervous system has an intrinsic ability for repair and regeneration, the central nervous system is, for the most part, incapable of self-repair and regeneration. There is currently no treatment for recovering human nerve function after injury to the central nervous system. In addition, multiple attempts at nerve re-growth across the PNS-CNS transition have not been successful. There is simply not enough knowledge about regeneration in the central nervous system. In addition, although the peripheral nervous system has the capability for regeneration, much research still needs to be done to optimize the environment for maximum regrowth potential. Neuroregeneration is important clinically, as it is part of the pathogenesis of many diseases, including multiple sclerosis.
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