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FIGURE LEGENDS FIGURE 20.1 Time
FIGURE LEGENDS FIGURE 20.1 Time

... case between 12.5 h and 18.5 h). Source: From Bestman, Santos da Silva, and Cline (2008). FIGURE 20.2 Transcription factors regulate the diversity and complexity of dendrites. (A) Dendrite morphologies of representative class I, II, III, and IV dendritic arborization (da) sensory neurons in the Dros ...
12-4 Membrane Potential
12-4 Membrane Potential

...  The properties and distribution of the membrane channels involved determine the nature of the change o For example, in a resting membrane, the opening of sodium channels causes depolarization, whereas the opening of potassium channels causes hyperpolarization  The change in membrane potential ref ...
03/05 PPT
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... Principles of Axon Guidance • Chemoaffinity Hypothesis – the specificity of wiring is based on recognition of chemical cues • Axons reach their targets in a series of discrete steps • Different cells respond to the same guidance cues in different ways • Chemical cues exist at many points along the a ...
0pt20pt [1.44]Spike Train Correlations Induced [1ex] [1.44]by
0pt20pt [1.44]Spike Train Correlations Induced [1ex] [1.44]by

... The in-degree of a vertex is the number of its incoming edges, the number of its outgoing edges is called out-degree. In the adjacency matrix, the in-degree is the sum of all entries in the corresponding row. The out-degree is the sum of all entries in the corresponding column. ...
sion to superior salivatory neurons in rats
sion to superior salivatory neurons in rats

... GABA and glycine during the early postnatal period might serve as trophic factors [2, 3] to influence synapse maturation in developing SS neurons. The GABAergic excitatory action induced Ca2+ entry into neurons via NMDA receptors and voltagedependent Ca2+ channels. This Ca2+ influx is thought to be ...
rEvIEW - McLoon Lab
rEvIEW - McLoon Lab

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Supplementary Figure Legends - Word file

... Supplementary Figure 1: Example responses to pure tones and harmonic complex tones from a pitchselective neuron (a, d) (Unit M36n-514) and a non-pitch-selective neuron (b, e) (Unit M2p-140). a. Pure tone frequency response from a pitch-selective neuron. b. Pure tone frequency response from a non-pit ...
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Department of Electrical and Computer Engineering University of

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Human Physiology - Orange Coast College
Human Physiology - Orange Coast College

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Changes in muscle coordination with training

... freedom that characterize the output of the human motor system, their implementation necessarily requires that the motor centers in the brain instantiate highly organized patterns of facilitation and inhibition that are spatially, temporally, and functionally discrete and are tailored to the specifi ...
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Sympathetic and Parasympathetic

... Sympathetic mydriatics  Directly act on dilation pupillae to produce mydriatics (eg. Adrenaline as is tra-cameral injection, Phenylpherine drops 2.5-10%) and locaine ...
Introduction to Psychology
Introduction to Psychology

... often, but it does not affect the action potentials strength or speed. Intensity of an action potential remains the same throughout the length of the axon. ...
P312Ch02_Nervous System, Neurons Lecture
P312Ch02_Nervous System, Neurons Lecture

... interior voltage reaches +.040, another change occurs that causes K+ ions to rush out of the neuron, resulting in the interior voltage going from +.040 back toward 0. This whole process – change in the membrane, movement of ions, and change in voltage - is called an action potential. Think of the ru ...
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LESSON 2.4 WORKBOOK What do our neurons need to work

... their plus-end which, again, is oriented microscope photograph of towards the presynaptic terminal. So, the kinesin carrying a vesicle. motors use the polarity of the microtutransport moves materibules as a cellular GPS. These plus-end als from the axon terminal towards the cell body. directed motor ...
Nervous System
Nervous System

nervous system
nervous system

... which is considered the functional or (plysiological) unit of the nervous system. The reflex arc consists of: • A receptor organ: it is a sensory cell where stimulus is received. • A sensory (afferent) neuron: Its function is to conduct impulse from the receptor neuron to CNS. • An interneuron: The ...
Reading Part 5: The Nervous System
Reading Part 5: The Nervous System

... another thru the synapse (the gap between neurons). The axon terminal contains many membraneenclosed sacs called synaptic vesicles. They store many types of neurotransmitters which are chemicals that help the electrical impulse cross the synaptic gap btwn neurons. ...
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Structure and Function of Neurons - Assets
Structure and Function of Neurons - Assets

... on/within the ribosomes. Peripheral proteins, which are soluble and live in the cytoplasm, are synthesized on free polysomes and transported directly into the dendrites and axons. ...
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6 - smw15.org

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Slide 1

... FIGURE 1-18: Transport mechanisms at the blood–brain barrier. (a) BECs contain a number of transport mechanisms to allow homeostatic control of nutrients, ions and signaling molecules. (1) Na+ dependent symporters (A, ASC, LNAA, EAAT) eliminate amino acids from the brain, thus preventing excess acc ...
Orthopedic and Physical Therapy Objectives in
Orthopedic and Physical Therapy Objectives in

... r ~ 2muscles and muscle imbalance. Mechanical strain must be avoided during the This categorv has been left until last because period of early weakness to allow time for treat" treatment of weak muscles overlaps the treatment ment directed toward hypertrophy of remaining of esseitially normal (Categ ...
Chapter 3 Editable Lecture Notecards
Chapter 3 Editable Lecture Notecards

... a weaker stimulus does not produce a weaker action potential. If the neuron receives a stimulus of sufficient strength, it fires, but if it receives a weaker stimulus, it doesn’t. This is referred to as the “all-or-none law.” ...
Print this article - University of Toronto Journal of Undergraduate Life
Print this article - University of Toronto Journal of Undergraduate Life

... memories at the cellular level occurs when the strength of the corticostriatal synapse is modified, a phenomenon termed synaptic plasticity. In intact animal systems, this effect is reversed physiologically by low frequency stimulation of cortical afferents to the striatum. However, recent investiga ...
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Neuromuscular junction



A neuromuscular junction (sometimes called a myoneural junction) is a junction between nerve and muscle; it is a chemical synapse formed by the contact between the presynaptic terminal of a motor neuron and the postsynaptic membrane of a muscle fiber. It is at the neuromuscular junction that a motor neuron is able to transmit a signal to the muscle fiber, causing muscle contraction.Muscles require innervation to function—and even just to maintain muscle tone, avoiding atrophy. Synaptic transmission at the neuromuscular junction begins when an action potential reaches the presynaptic terminal of a motor neuron, which activates voltage-dependent calcium channels to allow calcium ions to enter the neuron. Calcium ions bind to sensor proteins (synaptotagmin) on synaptic vesicles, triggering vesicle fusion with the cell membrane and subsequent neurotransmitter release from the motor neuron into the synaptic cleft. In vertebrates, motor neurons release acetylcholine (ACh), a small molecule neurotransmitter, which diffuses across the synaptic cleft and binds to nicotinic acetylcholine receptors (nAChRs) on the cell membrane of the muscle fiber, also known as the sarcolemma. nAChRs are ionotropic receptors, meaning they serve as ligand-gated ion channels. The binding of ACh to the receptor can depolarize the muscle fiber, causing a cascade that eventually results in muscle contraction.Neuromuscular junction diseases can be of genetic and autoimmune origin. Genetic disorders, such as Duchenne muscular dystrophy, can arise from mutated structural proteins that comprise the neuromuscular junction, whereas autoimmune diseases, such as myasthenia gravis, occur when antibodies are produced against nicotinic acetylcholine receptors on the sarcolemma.
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