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Neurotransmitters
Neurotransmitters

... repackaged for future release, or else it is broken down metabolically. Neurotransmitter release The release of a neurotransmitter is triggered by the arrival of a nerve impulse (or action potential) and occurs through an unusually rapid process of cellular secretion, also known as exocytosis: Withi ...
Unit III Modules 9 to 13 Test Review
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... • Thus, a victim of curare poisoning may be aware of what is happening until the very end. • The victim can feel the paralysis progressing but is quickly unable to move, call out or gesture. • If artificial respiration is performed throughout, the victim usually recovers without ill effects. ...
SV3 Neuroscience n Behavior Oct 5 09
SV3 Neuroscience n Behavior Oct 5 09

... Action potentials travel along the axon, and arrive at the terminal buttons Chemical Messengers (neurotransmitters) are stored in synaptic vesicles When the action potential reaches the terminal button, vesicles fuse with the presynaptic membrane Neurotransmitters are released into the synaptic clef ...
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8Neurotrophins PCD

... Synthesis by Physiological Activity • The transcription of genes for CNS neurotrophins is regulated by various forms of neuronal activity. • It has been observed that levels of BDNF mRNA in hippocampus, cortex, and cerebellum can be changed by: - depolarization and Ca2+ influx - excitatory neurotran ...
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... Schwann cells - supporting cells of the PNS that myelinate axons. • Myelin sheath – whitish lipoprotein that surrounds and insulates the axon (nerve fiber) • Neurilemma - external layer containing bulk of cytoplasm with nucleus and organelles Schwann cell ...
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NEUROSCIENCE Review Questions CHOOSE THE LETTER THAT

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Neurology, Neurons, and EEG

... or charges is the reason there is a voltage associated with living cells. The membrane of a cell is what separates the charges leading to a voltage. Biologists call this a membrane voltage potential or simply…membrane potential. All living cells have some separation of ions (charges) on either side ...
MCB105 Motor Learning Lecture by Bence Olveczky 2015 Apr 8
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... Put the neurons in a chain (one neuron excites the next and so on) – synfire chain Chain propogates as a function of time. Record from neurons in RA – each neuron drives one muscle/muscle group. RA represents muscle (motor activity). How do you test that HVC represents time? Try to slow down signal ...
Membrane Transport
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Human Anatomy, First Edition McKinley&O'Loughlin

...  the vestibule and semicircular canals = the vestibular complex  contains two saclike, membranous labyrinth parts—the utricle and the saccule - interconnected through a ...
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action potential

Chapter 10 Somatic and Special Senses
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... Inner layer: The inner tunic consists of the _________________, which contains photoreceptors; The inner tunic covers the back side of the eye to the ciliary body. In the center is the yellow area, the _______________ _______________ with the _____________ _________ in its center, the point of sharp ...
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...  The All-or-None principle states that a neuron will fire with its maximum strength or not at all  neurons do not directly connect at a synapse; there is a slight gap (Synaptic Gap) across which the signal must be transmitted. Generally, neurotransmitters are responsible for transmitting the signa ...
gustatory and olfactory senses
gustatory and olfactory senses

... How does the ear then change vibration waves to mechanical sound? The ear converts energy of sound into nerve impulses. This process begins at the tympanic membrane. The vibrations that move the eardrum, and then consequently the three additional bones of the middle ear, are transmitted to the oval ...
Nervous System
Nervous System

... moves out of cell, making cell become more negative, returns cell to resting • Na+/K+ pump is also activated, moving 3 Na+ out for every 2 K+ in, makes cell more negative • Returns cell to rest (~-70mV) ...
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Neuromuscular junction



A neuromuscular junction (sometimes called a myoneural junction) is a junction between nerve and muscle; it is a chemical synapse formed by the contact between the presynaptic terminal of a motor neuron and the postsynaptic membrane of a muscle fiber. It is at the neuromuscular junction that a motor neuron is able to transmit a signal to the muscle fiber, causing muscle contraction.Muscles require innervation to function—and even just to maintain muscle tone, avoiding atrophy. Synaptic transmission at the neuromuscular junction begins when an action potential reaches the presynaptic terminal of a motor neuron, which activates voltage-dependent calcium channels to allow calcium ions to enter the neuron. Calcium ions bind to sensor proteins (synaptotagmin) on synaptic vesicles, triggering vesicle fusion with the cell membrane and subsequent neurotransmitter release from the motor neuron into the synaptic cleft. In vertebrates, motor neurons release acetylcholine (ACh), a small molecule neurotransmitter, which diffuses across the synaptic cleft and binds to nicotinic acetylcholine receptors (nAChRs) on the cell membrane of the muscle fiber, also known as the sarcolemma. nAChRs are ionotropic receptors, meaning they serve as ligand-gated ion channels. The binding of ACh to the receptor can depolarize the muscle fiber, causing a cascade that eventually results in muscle contraction.Neuromuscular junction diseases can be of genetic and autoimmune origin. Genetic disorders, such as Duchenne muscular dystrophy, can arise from mutated structural proteins that comprise the neuromuscular junction, whereas autoimmune diseases, such as myasthenia gravis, occur when antibodies are produced against nicotinic acetylcholine receptors on the sarcolemma.
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