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02/03
02/03

... RNA polymerase recognizes signals for chain termination. (1) Intrinsic: Termination site on template DNA consists of GC-rich sequences followed by A’s. Intramolecular hydrogen bonding causes formation of hairpin loop. ...
Chapter 12 Study Guide
Chapter 12 Study Guide

... 12 rules stating that in DNA a purine on one strand always pairs with a pyrimidine on the opposite strand 13 describes a microorganism or virus that causes disease and that is highly infectious 14 a Y-shaped point that results when the two strands of a DNA double helix separate so that the DNA molec ...
protein synthesis study guide
protein synthesis study guide

... 2. Describe the Beadle and Tatum experiment with mold in detail – use the diagram below to help. The logic behind both the experiment and the results are critical. 3. What was Beadle and Tatum’s final hypothesis? 4. Look at the two diagrams below. Label the structures in each and explain what is hap ...
DNA (Deoxyribonucleic Acid)
DNA (Deoxyribonucleic Acid)

... Purpose: DNA copies itself to ensure that each new cell that is produced in gets the correct number of chromosomes and receives an EXACT copy of the DNA molecule. ...
AP Biology Discussion Notes
AP Biology Discussion Notes

... –E.coli has about 4.6 Million nucleotide/base pairs and replicates DNA, then divides into 2 new cells in less than an hour! –Humans have ~6 Billion nucleotide/base pairs and replicate their DNA in a few hours ...
A closer look at Transcription and Translation
A closer look at Transcription and Translation

...  The DNA is unwound and the double helix is separated ...
DNA Replication
DNA Replication

...  Early scientists thought protein was the cell’s ...
Document
Document

... A research technique developed to move rapidly up or down a chromosome in search of a particular gene. It enables researchers to make large jumps over uninformative regions of DNA. Chromosome jumping is used to bypass regions difficult to clone, such as those containing repetitive DNA, that cannot b ...
DNA to Protein
DNA to Protein

... • A gene should carry all the information for a full polypeptide including information for defining initiation and termination • Just one DNA strand (the template strand) is used to make the RNA. • For different genes in the same DNA molecule, the roles of these strands may be reversed. ...
DNA and RNA Review Sheet Answers
DNA and RNA Review Sheet Answers

... 25. What two other enzymes (that we learned about) are involved in the process of DNA replication Primase – adds RNA primers on both leading and lagging Ligase – glues the backbones of sugars and phosphates together after the RNA primers are removed 26. If the sequence of nucleotides on the original ...
APDNA 2015 16
APDNA 2015 16

... Hershey and Chase (1952): DNA is the genetic material Erwin Chargaff (1947): The amount of thymine = adenine Watson and Crick (1953): Structure of DNA Rosalind Franklin (1951): X-Ray Structure of DNA Meselson and Stahl (1958): DNA Replication ...
Chapter 7: Nucleic Acids and Protein Synthesis
Chapter 7: Nucleic Acids and Protein Synthesis

... • Because each of the two strands of DNA double helix has all the information, by the mechanism of base pairing, to reconstruct the other half, the strands are said to be complementary • Even in a long and complicated DNA molecule, each half can specifically direct the sequence of the other half by ...
DNA replication
DNA replication

... The “parent” molecule has two complementary strands of DNA. Each is base paired by hydrogen bonding with its specific partner: A with T G with C ...
DNA is
DNA is

... http://www.biology-online.org/2/8_mutations.htm ...
Griffith`s Transformation Experiment
Griffith`s Transformation Experiment

... This bond is very strong, and for this reason DNA is remarkably stable. DNA can be boiled and even autoclaved without degrading! 5’ and 3’ The ends of the DNA or RNA chain are not the same. One end of the chain has a 5’ carbon and the other end has a 3’ carbon. ...
Discovery of nucleic acid • DNA is made up of:
Discovery of nucleic acid • DNA is made up of:

... • Overall mistake rate = 1 bp / 1,000,000,000 bps Mutations • Other hazards damage DNA • Body temperature = 98.6 °F = 10,000 bp lost / day • Ultraviolet light ...
Replication - University of Idaho
Replication - University of Idaho

... Topoisomerase - allows DNA to move from a supercoiled state to a relaxed state. Enzyme also called DNA gyrase. Helicase - unwinds the DNA double helix. Destabilizing enzymes (SSBPs) DNA single strand binding proteins to keep the strands separated. Initiator protein - Binds to the DNA at the origin o ...
chapter 12 - cloudfront.net
chapter 12 - cloudfront.net

... brought into the ribosome and attached to the growing polypeptide chain • That job is done by transfer RNA • The codon matches up with complementary bases on the tRNA to tell it which amino acid to bring in • The three bases on the tRNA molecule, called the anticodon, are complementary to one of the ...
Unit 3: CHEMICAL PRINCIPLES:
Unit 3: CHEMICAL PRINCIPLES:

... terminator region in the DNA. (UAA, UAG, UGA) ...
8.2 Structure of DNA - Perry Local Schools
8.2 Structure of DNA - Perry Local Schools

... • binds to specific amino acids Ribosomal RNA (rRNA) – makes up the ribosomes where proteins are made ...
File
File

... Purpose: To explore the structure of a DNA molecule. Background Information: DNA stands for deoxyribonucleic acid. DNA is the genetic material found in the nucleus of most cells, and can referred to as the blueprint of life, it controls the production of proteins within the cell, that make-up who yo ...
Chapter 4 - Version A
Chapter 4 - Version A

... 1. Franklin's X-ray diffraction images revealed that the structure of DNA involved a complete helical turn every 3.4 nanometers. _________________________ ...
DNA
DNA

... 2. DNA polymerase brings in nucleotides to the existing DNA strands (using complimentary base pairing) and replication proceeds in both directions from the origin - one chain is continuous - one chain is brought in pieces 3. DNA ligase joins pieces on non-continuous strand 4. Replication ends when p ...
Chapter 4 - Version B
Chapter 4 - Version B

... 26. The percentage composition of a nucleic acid molecule found in bacterial cells is 32.3% adenine 30.7% thymine 19.1% cytosine 17.9% guanine The molecule is most likely to be a. double-stranded DNA. b. mitochondrial DNA. c. messenger RNA. ...
RNA and Protein Synthesis
RNA and Protein Synthesis

... Types of Mutations Mutations are heritable changes in genetic information. There are two categories of mutations: gene mutations and chromosomal mutations. ▶ Gene mutations produce changes in a single gene. Point mutations involve only one or a few nucleotides. Substitutions, insertions, and deletio ...
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Helicase



Helicases are a class of enzymes vital to all living organisms. Their main function is to unpackage an organism's genes. They are motor proteins that move directionally along a nucleic acid phosphodiester backbone, separating two annealed nucleic acid strands (i.e., DNA, RNA, or RNA-DNA hybrid) using energy derived from ATP hydrolysis. There are many helicases resulting from the great variety of processes in which strand separation must be catalyzed. Approximately 1% of eukaryotic genes code for helicases. The human genome codes for 95 non-redundant helicases: 64 RNA helicases and 31 DNA helicases. Many cellular processes, such as DNA replication, transcription, translation, recombination, DNA repair, and ribosome biogenesis involve the separation of nucleic acid strands that necessitates the use of helicases.
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