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Cloning - UNM Biology
Cloning - UNM Biology

Day 58 - upwardsapbio
Day 58 - upwardsapbio

... Finish DNA replication and do a quick overview of Excision Repair. Don’t get too bogged down with Telomeres, non-coding regions of DNA that play a role in cell death. When telomeres get short enough…the cell has divided enough, it’s time for the cell to die. DNA replication is the process by which D ...
DNA Structure and Function Video
DNA Structure and Function Video

... ● ______________________ (A)  ● ______________________ (T)  ● ______________________ (G)  ● ______________________ (C)  ...
DNA-The Alphabet of Life
DNA-The Alphabet of Life

PCR-Presentation
PCR-Presentation

... Introduction • PCR, polymerase chain reaction, is an invitro technique for amplification of a region of DNA whose sequence is known or which lies between two regions of known sequence • Before PCR, DNA of interest could only be amplified by over-expression in cells and this with limited yield ...
Slide 1
Slide 1

... • This “error prone” repair represents a last chance for survival. Another name for this is “SOS repair”. ...
Recombinant DNA technology
Recombinant DNA technology

... 1) develop a basic understanding of the function and regulation of known gene products. 2) identify new genes whose protein products have not been isolated . 3) correct endogenous genetic defects ...
DNA TAKS QUESTIONS SPRING 2003 – 11: (38) In DNA, which of
DNA TAKS QUESTIONS SPRING 2003 – 11: (38) In DNA, which of

... 40 In all plant and animal cells, the nucleus contains long molecules of DNA. Which of the following best describes the function of DNA? F DNA provides the shape and structure of the nucleus. G DNA packages materials for transport through the nucleus. H DNA carries materials into and out of the nucl ...
File - High School Biology
File - High School Biology

... Mutations happen when the sequence of bases in the DNA gets changed. Mutations can be caused by mistakes in reading the DNA and can also be caused by environmental factors such as radiation, UV rays from the sun, or smoking. Original A T C C G T G ...
Document
Document

... upcoming scene, investigators will compare the DNA profiles of a known suspect and an unknown biological sample collected from the victim. You are asked to write up a brief explanation of the primary technique required for discussion in the scene. Which technique should you write about? A. DNA finge ...
DNA structure and replication Three key features needed for any
DNA structure and replication Three key features needed for any

... What was known? 1) Hereditary factors were associated with specific traits 2) One-gene-one-protein model - from mapping genes for biosynthetic pathways 3) Genes are on chromosomes 4) Chromosomes are made up of DNA and protein ...
Document
Document

... encoded protein. Nonsense mutations are changes that cause the substitution of a stop codon for an amino acid in the encoded protein. Synonymous mutations are changes in the nucleic acid sequence in the coding region of a gene that do not cause a change in the encoded protein. Nonsense mutations are ...
DNA and RNA
DNA and RNA

... WHY DOES DNA HAVE TO BE REPLICATED? DNA must be replicated as a cell undergoes cell division (mitosis or meiosis) to produce new cells. This ensures that the newly produced cells also have the same copy of DNA that was in the original cell before it underwent cell division. During DNA replication, ...
Biology 303 EXAM II 3/14/00 NAME
Biology 303 EXAM II 3/14/00 NAME

Xeroderma Pigmentosum (XP)
Xeroderma Pigmentosum (XP)

... Mutation in one of the proteins involved in NER Inability to repair UV damaged DNA Buildup of mutations in skin cells Increased incidence of skin cancers ...
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Slide ()

... PJ, Weil some P. Harper's Illustrated Biochemistry, 30e;transfer, 2015 Available similar. RNA Citation: is subjected to electrophoresis before blot transfer. This requires different steps from those of DNA primarilyat: to ensure that the http://mhmedical.com/ Accessed: August ...
Slide 1 - New Century Academy
Slide 1 - New Century Academy

... -6 billion base pairs -Genome will fill 1,200 AP bio books -Replicated in just a few hours -Errors occur in 1/10 billion base pairs -Most of Replication is known about prokaryotic cells – Eukaryotic is similar to ...
Basic DNA
Basic DNA

... The ladder model • The structure of DNA can be understood more easily by untwisting the double helix and displaying the molecule as if it were a ladder. • The side rails of the ladder (the “backbone”) are alternating phosphate and sugar molecules. The rungs are paired nitrogen base molecules held t ...
Protein Synthesis Review
Protein Synthesis Review

... 3. Compare and contrast DNA replication and transcription. 4. Name three types of RNA (one is from DNA replication, two from protein synthesis) described and explain the function of each. 5. How many different DNA triplets are possible? 6. The DNA triplet “CGA” is transcribed into which RNA codon? a ...
mutation - ahsbognasbi4u
mutation - ahsbognasbi4u

Name Date ______ Period
Name Date ______ Period

... What does our DNA determine about us? ...
DNA and RNA Notes
DNA and RNA Notes

... Complete the missing DNA strand by adding the complementary bases. ...
Chapter 9, part A
Chapter 9, part A

... • In wild cells they at as a type of disease defense by destroying bacteriophage DNA in bacterial cells • Cannot digest (host) DNA with methylated cytosines • May cut DNA blunt or with “sticky ends” ...
1 Genetics (BIL-250) Review Questions #1 (2
1 Genetics (BIL-250) Review Questions #1 (2

... (3-1) Draw a DNA replication fork and identify and label the locations of the following major components: (1) 5’ and 3’ ends of each strand, (2) leading strand, (3) lagging strand, (4) single-stranded binding proteins, (5) DNA polymerase, (6)Okazaki fragments, (7) RNA primer, (8) DNA helicase, (9) D ...
Green Genes: DNA Curriculum
Green Genes: DNA Curriculum

< 1 ... 292 293 294 295 296 297 298 299 300 ... 331 >

DNA repair



DNA repair is a collection of processes by which a cell identifies and corrects damage to the DNA molecules that encode its genome. In human cells, both normal metabolic activities and environmental factors such as UV light and radiation can cause DNA damage, resulting in as many as 1 million individual molecular lesions per cell per day. Many of these lesions cause structural damage to the DNA molecule and can alter or eliminate the cell's ability to transcribe the gene that the affected DNA encodes. Other lesions induce potentially harmful mutations in the cell's genome, which affect the survival of its daughter cells after it undergoes mitosis. As a consequence, the DNA repair process is constantly active as it responds to damage in the DNA structure. When normal repair processes fail, and when cellular apoptosis does not occur, irreparable DNA damage may occur, including double-strand breaks and DNA crosslinkages (interstrand crosslinks or ICLs).The rate of DNA repair is dependent on many factors, including the cell type, the age of the cell, and the extracellular environment. A cell that has accumulated a large amount of DNA damage, or one that no longer effectively repairs damage incurred to its DNA, can enter one of three possible states: an irreversible state of dormancy, known as senescence cell suicide, also known as apoptosis or programmed cell death unregulated cell division, which can lead to the formation of a tumor that is cancerousThe DNA repair ability of a cell is vital to the integrity of its genome and thus to the normal functionality of that organism. Many genes that were initially shown to influence life span have turned out to be involved in DNA damage repair and protection.
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