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DNA Typing
DNA Typing

Heredity test
Heredity test

... ______ 28. A disorder, such as cystic fibrosis, is known as __________ if the child must receive an allele for the disease from each parent in order to have the disease. A. dominant B. recessive C. big D. small ______ 29. A _____________ is a physical or chemical agent that causes damage to DNA. A. ...
Structure of DNA
Structure of DNA

... when he repeated Griffith’s work? Molecule-destroying enzyme he used ...
DNA: The Molecule of Heredity
DNA: The Molecule of Heredity

... 14. Number the steps of DNA replication in the correct order (1, 2, 3) _______Polymerase travels down the DNA parent strand from the 3’ to 5’ direction. ______ DNA unwinds ______ Ligase binds okazaki fragments together 15. Why is DNA replication called “semi-conservative”? _________________________ ...
Chapter 13 Review answers
Chapter 13 Review answers

... 15. What are the different lengths of noncoding DNA called? 16. What is a genome? 17. Why don’t vaccines make you sick? ...
Site Directed Nucleases (SDN) for targeted
Site Directed Nucleases (SDN) for targeted

... outcome of the DNA double strand break repair. SDN-1: When the SDN is used in the absence of a DNA repair template (see SDN-2/-3), the outcome is a targeted, non-specific genetic deletion mutation. In this case, the position of the DNA DSB is precisely selected, but the DNA repair by the host cell i ...
Topic 4.4 - Genetic Engineering and Biotechnology
Topic 4.4 - Genetic Engineering and Biotechnology

... onto the recombinant strand some gene sequence that will cause the host to display an easily observable characteristic. Such a sequence that is often used codes for phosphorescence, causing the host cell to glow if the transfer has been completed successfully. ...
DNA Structure and Replication
DNA Structure and Replication

... 14. A(n) ____________________ is a harmless version of a disease-causing microbe that can stimulate a person’s immune system to ward off infection by the infectious form of the microbe. 15. Griffith’s experiment showed that live bacteria without capsules acquired the ability to make capsules from de ...
Chapter 16 notes
Chapter 16 notes

... phage from cells, centrifuged & measured radioactivity in supernatant Results: radioactivity in supernatant, therefore, protein did not enter the bacteria ...
1 - contentextra
1 - contentextra

... DNA includes covalent and hydrogen bonds. The hydrogen bonds allow linkage of the two chains of DNA between a purine and a pyrimidine nitrogenous base. Covalent bonds occur everywhere else within the DNA molecule. The covalent bonds are much stronger than the hydrogen bonds. Because of the weak hydr ...
Basic principles of DT40
Basic principles of DT40

... • Good model for genome stability in mammals • Complementation by human genes • Good database ...
Biotech Overview
Biotech Overview

... copies of a gene is PCR PCR requires short pieces of single-stranded DNA which match up to a regions at the beginning & end of the gene to be amplified, called primers Primers are required as a starting point for the DNA polymerase, the same enzyme used in DNA replication DNA polymerase then makes c ...
DNA Technology
DNA Technology

... What are the implications of cloning? How will cloning affect the medical field? What will be the effect on the gene pool? Is there potential for abuse? How should it be regulated? Would you consider cloning yourself? ...
Suggested answers to Exercise - Bio-662
Suggested answers to Exercise - Bio-662

Methyl methanesulphonate (MMS, Fig
Methyl methanesulphonate (MMS, Fig

... The vital function of DNA as the principal carrier of genetic information is constantly threatened by various attacks against its integrity. In general, the causative factor can be physical (such as radiation – ultraviolet, ionizing) or chemical. In the aqueous environment inside the cell, hydrolyti ...
What do Genes Look Like - Effingham County Schools
What do Genes Look Like - Effingham County Schools

... A. _____________________________ (#1) - changes in a single gene. 2 types of gene mutations1. _______________________________- affect only one nucleotide *Can be caused by substitutions 2. _____________________________- type of point mutation where nucleotide is inserted or deleted; affects every am ...
DNA Structure and Replication Integrated Science 4
DNA Structure and Replication Integrated Science 4

... The percentages of corresponding bases was equal in almost any sample of DNA regardless of the organism from which it came. 9. Describe the basic structure of a DNA molecule (pg. 357-358) double helix – a pair of twisted strands bonded together by nitrogenous bases ...
Vocabulary:
Vocabulary:

... DNA  bases:  When  you  read  a  book,  the  order  of  the  26  letters  of  our  alphabet   forms  words  and  sentences  that  help  you  understand  the  author’s  meaning.   The  alphabet  of  your  DNA  only  has  4  letters ...
Why the scientists want to extract the DNA from the cells? With the
Why the scientists want to extract the DNA from the cells? With the

... Thirdly, the DNA samples can help with the extinction of different kinds of organisms, to maintain the biodiversity. Lots of organisms face extinction, but once their DNA samples store in the database, they still have chances to rebirth again, in another way to keep the world’s biodiveristy. Finally ...
No Slide Title
No Slide Title

biotechnology
biotechnology

... (2) Polymerase chain reaction (4) Transcription ...
DNA repair - Journal of Cell Science
DNA repair - Journal of Cell Science

... Double-strand breaks (DSBs) can be repaired by either HR or NHEJ. HR uses a homologous DNA template and is ...
DNA - The Double Helix
DNA - The Double Helix

... Recall that the nucleus is a small spherical, dense body in a cell. It is often called the "control center" because it controls all the activities of the cell including cell reproduction, and heredity. How does it do this? The nucleus controls these activities by the chromosomes. Chromosomes are mic ...
building linear and plasmid dna models
building linear and plasmid dna models

Chapter 13
Chapter 13

... DNA Libraries - II The probabilities are staggering! • Consider the formula on page 406 for probability of finding a particular fragment in N clones • Suppose you seek a 99% probability of finding a given fragment in N clones of 10 kbp fragments • If your library is from the human genome, you would ...
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DNA repair



DNA repair is a collection of processes by which a cell identifies and corrects damage to the DNA molecules that encode its genome. In human cells, both normal metabolic activities and environmental factors such as UV light and radiation can cause DNA damage, resulting in as many as 1 million individual molecular lesions per cell per day. Many of these lesions cause structural damage to the DNA molecule and can alter or eliminate the cell's ability to transcribe the gene that the affected DNA encodes. Other lesions induce potentially harmful mutations in the cell's genome, which affect the survival of its daughter cells after it undergoes mitosis. As a consequence, the DNA repair process is constantly active as it responds to damage in the DNA structure. When normal repair processes fail, and when cellular apoptosis does not occur, irreparable DNA damage may occur, including double-strand breaks and DNA crosslinkages (interstrand crosslinks or ICLs).The rate of DNA repair is dependent on many factors, including the cell type, the age of the cell, and the extracellular environment. A cell that has accumulated a large amount of DNA damage, or one that no longer effectively repairs damage incurred to its DNA, can enter one of three possible states: an irreversible state of dormancy, known as senescence cell suicide, also known as apoptosis or programmed cell death unregulated cell division, which can lead to the formation of a tumor that is cancerousThe DNA repair ability of a cell is vital to the integrity of its genome and thus to the normal functionality of that organism. Many genes that were initially shown to influence life span have turned out to be involved in DNA damage repair and protection.
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