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molecular biology review sheet
molecular biology review sheet

... Section 2 – Nucleic acids store information in their sequences of chemical units. Section 3 – DNA replication is the molecular mechanism of inheritance. Section 4 – A gene provides the information for making a specific protein. Section 5 – There are two main steps from gene to protein. Section 6 – M ...
DNA Model and Replication Name: Objective: The students will
DNA Model and Replication Name: Objective: The students will

... 1. Which two molecules make up the “side” of the DNA molecule? 2. Which molecules make up the “rungs” of the molecule? 3. How does the model you constructed differ from an actual DNA molecule, besides being made of candy? 4. Describe how the replication process creates two exact copies. ...
Chapter 19 – Molecular Genetic Analysis and Biotechnology
Chapter 19 – Molecular Genetic Analysis and Biotechnology

... – Yeast artificial chromosomes – Yeast origin of replication, centromere, telomeres – ~600kb – 1,000kb ...
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... backbone at 180o • Actually a distorted ladder with poles closer to each other, on one side • Major/minor groove recognition ...
DNA Damage and Apoptosis in Cerebral White Matter Lesions
DNA Damage and Apoptosis in Cerebral White Matter Lesions

... hypoperfusion1. However, other factors, such as blood brain barrier breakdown and immunological mechanisms may play a role. Microglial activity is up-regulated in WML, but is also widespread in non-lesional white matter from cases with WML, suggesting that there is a field-effect of abnormal white m ...
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... known that the virus injects its genetic material into the bacterium which had to DNA or proteins. ...
DNA Notes Organizer
DNA Notes Organizer

... e. Which enzyme is responsible for linking together together the many Okazaki fragments? ...
Mark scheme - biologypost
Mark scheme - biologypost

... By hydrolysis; Same restriction enzyme used (to cut each type of DNA); Acts on specific base sequence; Staggered cut / leaving sticky ends / OR add sticky ends to the cut DNA shown on annotated diagram; Complementary base pairing between 2 DNA molecules (at sticky ends); Ligase: Splices/joins DNA pi ...
DNA
DNA

... B. TRANSLATION: Interpreting the code from the mRNA - on the ribosomes. tRNA (transfer) carries amino acids and bring them to ribosomes to be assembled into proteins The order of amino acids determines the type of polypeptide assembled. (protein) ...
Unit 4 Review: Molecular Genetics
Unit 4 Review: Molecular Genetics

... a) silent mutation: base-pair substitution with no effect (ex: the amino acid is the same due to redundancy of the code or the amino acid is really similar in chemical properties) b) missense mutation: substitute base-pair with some effects (new amino acid but some differences in folding; ex: hemogl ...
Restriction Enzymes - Seattle Central College
Restriction Enzymes - Seattle Central College

... • Restriction enzymes are bacterial enzymes that cleave the sugar-phosphate backbone of the DNA at specific nucleotide. • They are member of the class of nucleases. Endonucleases cleave nucleic acid at internal positions, while exonucleases progressively digest from the ends of the nucleic acid mole ...
Ribosome and Introduction to DNA Forensics
Ribosome and Introduction to DNA Forensics

Sect 12.2
Sect 12.2

... Summarize the role of the enzymes involved in the replication of DNA. Explain how leading and lagging strand are synthesized differently. ...
SB2a Build DNA using the Nucleotides Then Print
SB2a Build DNA using the Nucleotides Then Print

... when you made RNA? Where does DNA Replication take place? Where does transcription take place in a cell? ...
Chapter Review
Chapter Review

... _____ 5. In a DNA molecule, which of the following bases pair together? a. adenine and cytosine b. thymine and adenine c. thymine and guanine d. cytosine and thymine _____ 6. A gene can be all of the following EXCEPT a. a set of instructions for a trait. b. a complete chromosome. c. instructions for ...
A8xb1e3x8x1 (2)
A8xb1e3x8x1 (2)

... paper to represent an organism’s genome Have your partner write a short DNA sequence on a short strip of paper to represent a marker gene Using the chart provided, work with your partner to figure out how to insert the marker gene into the genome ...
15.2_Recombinant_DNA
15.2_Recombinant_DNA

Chapter 5: DNA
Chapter 5: DNA

...  DNA provides the code, or set of rules, for making proteins. ...
DNA Notes Part 1
DNA Notes Part 1

... - Hold all genetic information. - Chromosomes are passed on to an offspring by its parents. Examples: Humans = 46 Shrimp = 254 Chimps = 48 Chicken = 78 Gorilla = 48 Wolf ...
7th Grade Science Name: ______ DNA Study Guide Per: _____
7th Grade Science Name: ______ DNA Study Guide Per: _____

... 28. Another type of molecule that helps make proteins is called ____________. 29. RNA stands for ___________________________. One difference between DNA and RNA is that RNA has the base __________________ or U instead of thymine. Please read Figure 2 1-7 to see how RNA helps make protein. 30. The fi ...
DNA Worksheet - Answers 1. Deoxyribonucleic acid 2. Variable
DNA Worksheet - Answers 1. Deoxyribonucleic acid 2. Variable

NAME: MAKING A DNA MODEL PERIOD:______ DATE:______
NAME: MAKING A DNA MODEL PERIOD:______ DATE:______

... A molecule of DNA is composed of two backbones and four types of chemical bases. The backbone is formed by a chain of alternating phosphates and sugars. Each sugar molecule provides the location for the nitrogen bases to attach. The four types of bases are adenine, thymine, guanine, and cytosine. Ty ...
L05v04.stamped_doc
L05v04.stamped_doc

... polymerase will come along and insert the correct base-- a C, to base pair with the G. And then the enzyme DNA ligase will seal the nick. [00:01:21.18] There's a very similar type of DNA damage called depurination, which happens to purines, which are Gs or As. This class of mutations cleave the bond ...
18 - cloudfront.net
18 - cloudfront.net

... the plasmid ( and the foreign DNA) from those that don’t. Genes for resistance to antibiotics, compounds that kill bacteria, are commonly used as markers. A marker makes it possible for researchers to mix recombinant plasmids with a culture of bacteria, adds enough DNA to transform one cell in a mil ...
Unit 4 Genetics
Unit 4 Genetics

... DNA from the outside (DNA from another organism) • That external DNA combines with the cell’s DNA • As the cell copies its own DNA, it also copies the external DNA, since the 2 were combined during transformation ...
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DNA repair



DNA repair is a collection of processes by which a cell identifies and corrects damage to the DNA molecules that encode its genome. In human cells, both normal metabolic activities and environmental factors such as UV light and radiation can cause DNA damage, resulting in as many as 1 million individual molecular lesions per cell per day. Many of these lesions cause structural damage to the DNA molecule and can alter or eliminate the cell's ability to transcribe the gene that the affected DNA encodes. Other lesions induce potentially harmful mutations in the cell's genome, which affect the survival of its daughter cells after it undergoes mitosis. As a consequence, the DNA repair process is constantly active as it responds to damage in the DNA structure. When normal repair processes fail, and when cellular apoptosis does not occur, irreparable DNA damage may occur, including double-strand breaks and DNA crosslinkages (interstrand crosslinks or ICLs).The rate of DNA repair is dependent on many factors, including the cell type, the age of the cell, and the extracellular environment. A cell that has accumulated a large amount of DNA damage, or one that no longer effectively repairs damage incurred to its DNA, can enter one of three possible states: an irreversible state of dormancy, known as senescence cell suicide, also known as apoptosis or programmed cell death unregulated cell division, which can lead to the formation of a tumor that is cancerousThe DNA repair ability of a cell is vital to the integrity of its genome and thus to the normal functionality of that organism. Many genes that were initially shown to influence life span have turned out to be involved in DNA damage repair and protection.
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