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DNA Replication Paper Clip Activity
DNA Replication Paper Clip Activity

... STEP SEVEN: To demonstrate a gene mutation, place one of your paper clip hGH DNA strands in front of you. Identify the second nucleotide base called Adenine (A), which is blue. To cause a mutation, remove this 2nd blue clip and replace it with a red Cytosine (C) clip. You have just demonstrated how ...
Ch 16 DNA structure and replication powerpoint
Ch 16 DNA structure and replication powerpoint

... mechanisms, and external factors, including radiation and reactive chemicals, can cause random changes B. The environmental (various selection pressures) determine whether or not a mutation is detrimental, beneficial or neutral. C. Mutations are the primary source of genetic variation. ...
Nucleotide
Nucleotide

Building DNA -Hemoglobin Gene
Building DNA -Hemoglobin Gene

... http://www.msu.edu/course/isb/202/ebertmay/drivers/nucleotide.jpg ...
1. Explain why researchers originally thought
1. Explain why researchers originally thought

... 2. Okazaki fragments make up which replicating strand? lagging Telomeres are special nucleotide sequences 3. _____ found at the ends of eukaryotic chromosomal DNA molecules. 4. Which proteins make up almost half of chromatin? histones 5. The less compacted, more dispersed, euchromatin “true chromati ...
PCR - churchillcollegebiblio
PCR - churchillcollegebiblio

... forward primer and one is a reverse primer. When they have bound to the complementary sequences on the genomic DNA template strand, they show the Taq polymerase where to start DNA synthesis. The primers are responsible for making sure that only the region of interest is copied. • This is double-stra ...
Investigation 3: DNA - connorericksonbiology
Investigation 3: DNA - connorericksonbiology

... error in every 10,000 paired nucleotides. • A change in the nucleotide sequence at even one location is called a mutation and can have serious effects in new cells. • A repair process helps to keep the error rate to one in 1 billion nucleotides. • DNA can also be damaged by a variety of things such ...
Assessment Schedule
Assessment Schedule

... DNA before cell division / new cells formed (from mitosis) have an exact copy, with same instructions (information) / structure / function. ...
Level 3 Biology (90715) 2011 Assessment Schedule
Level 3 Biology (90715) 2011 Assessment Schedule

... DNA before cell division / new cells formed (from mitosis) have an exact copy, with same instructions (information) / structure / function. ...
DNA
DNA

... replication stops. Thus, the "C" reaction produces new strands that terminate at positions corresponding to the G's in the strand being sequenced. (Note that when long strands are being sequenced the concentration of the reaction-terminating nucleotide must be carefully chosen, so that a "normal" C ...
File
File

DNA - The Double Helix
DNA - The Double Helix

... molecule or repeating nucleotides. Examine the nucleotides closer. Two of the bases are purines - adenine and guanine. The pyrimidines are thymine and cytosine. Note that the pyrimidines are single ringed and the purines are double ringed. Color the nucleotides using the same colors as you colored t ...
Chapter 8 How Genes Work
Chapter 8 How Genes Work

... B. The change alters the amino acid sequence of the protein. C. The change causes the blood cells to divide in an uncontrolled way. D. The change creates a second strand of mRNA for each RNA molecule. ...
Chapter 13: The Molecular Basis of Inheritance
Chapter 13: The Molecular Basis of Inheritance

... ◉ Naturally occurring DNA molecules are very long, and a single molecule usually carries many genes. ◉ To work directly with specific genes, scientists have developed methods for preparing well-defined segments of DNA in multiple identical copies, a process called DNA cloning. ○ One common approach ...
3 Intro to Restriction Enzymes
3 Intro to Restriction Enzymes

... replicated in another species. ...
Plasmid
Plasmid

...  Plasmids are extremely valuable tools in the fields of molecular biology ...
File - Ms. Wilson`s Biology Class
File - Ms. Wilson`s Biology Class

... Read the text below and answer the following questions: 1. In order to speed up the copying process (replication), DNA replication begins at ___________ locations along each chromosome. 2. The two DNA strands are pulled apart and copied in both directions at the rate of about _________ nucleotides p ...
Section 12–1 DNA (pages 287–294)
Section 12–1 DNA (pages 287–294)

Ch. 13 - Genetic Engineering
Ch. 13 - Genetic Engineering

... the cell, the external DNA gets incorporated into the bacterium’s own DNA. Recombinant DNA has been made.  The cell has been transformed. It will make a new protein(s). ...
Ataxia- telangiectasia Mutated (ATM)
Ataxia- telangiectasia Mutated (ATM)

... DNA can be damaged from two sources: ...
Molecular Genetics 2- Central Dogma PDQ
Molecular Genetics 2- Central Dogma PDQ

... can’t both strands of DNA be replicated in the same fashion? 7. Diagram the replication fork. Include: a. the leading strand b. the lagging strand c. prime orientation of both parent strand and both daughter strands. d. Replisome e. Okazaki fragments 8. Why is telomerase necessary during the replica ...
DNA RNA and Proteins
DNA RNA and Proteins

... • 1953: Watson and Crick get credit for discovery of the structure of DNA • 1962: Crick, Watson, and Wilkins were all awarded Nobel Prize for the discovery of the structure of DNA, but Franklin did not due to her death prior to the award. ...
chapter 14 15 16 study guide
chapter 14 15 16 study guide

... one origin of replication; smaller genome; faster replication; doesn’t have a telomere because it is circular Eukaryotic: linear dna, double helix, multiple origins of replication, more complicated lots of enzymes, have telomeres, histones RNA primase: synthesizes RNA primer (using A, U, C, G) about ...
DNA - hedrickbiology
DNA - hedrickbiology

... was DNA or protein ► Avery already concluded that genes are found on DNA. Why are Hershey and Chase ...
Tandem repeats - Trimble County Schools
Tandem repeats - Trimble County Schools

... Short Tandem Repeats (STR) • Latest method of DNA analysis • Locations on the chromosome that contain short sequence elements that repeat • Less than 400 base pairs • Shorter than RFLP • Less susceptible to degradation • Can be recovered from bodies or stains that have been subject to decomposition ...
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DNA repair



DNA repair is a collection of processes by which a cell identifies and corrects damage to the DNA molecules that encode its genome. In human cells, both normal metabolic activities and environmental factors such as UV light and radiation can cause DNA damage, resulting in as many as 1 million individual molecular lesions per cell per day. Many of these lesions cause structural damage to the DNA molecule and can alter or eliminate the cell's ability to transcribe the gene that the affected DNA encodes. Other lesions induce potentially harmful mutations in the cell's genome, which affect the survival of its daughter cells after it undergoes mitosis. As a consequence, the DNA repair process is constantly active as it responds to damage in the DNA structure. When normal repair processes fail, and when cellular apoptosis does not occur, irreparable DNA damage may occur, including double-strand breaks and DNA crosslinkages (interstrand crosslinks or ICLs).The rate of DNA repair is dependent on many factors, including the cell type, the age of the cell, and the extracellular environment. A cell that has accumulated a large amount of DNA damage, or one that no longer effectively repairs damage incurred to its DNA, can enter one of three possible states: an irreversible state of dormancy, known as senescence cell suicide, also known as apoptosis or programmed cell death unregulated cell division, which can lead to the formation of a tumor that is cancerousThe DNA repair ability of a cell is vital to the integrity of its genome and thus to the normal functionality of that organism. Many genes that were initially shown to influence life span have turned out to be involved in DNA damage repair and protection.
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