mbglecture7dnarepair
... 5’-cleavage site cut by ERCC1-XPF nuclease and 3’-cleavage site cut by XPG nuclease (similar to UvrC in E. coli) 24-32 nucleotide long DNA strand is released that is filled in by a polymerase and sealed by DNA ligase. Xeroderma pigmentosum disease caused by mutations in XP_ (NER) genes. Patients are ...
... 5’-cleavage site cut by ERCC1-XPF nuclease and 3’-cleavage site cut by XPG nuclease (similar to UvrC in E. coli) 24-32 nucleotide long DNA strand is released that is filled in by a polymerase and sealed by DNA ligase. Xeroderma pigmentosum disease caused by mutations in XP_ (NER) genes. Patients are ...
Lesson 3
... DNA to form a base pair. Adenine and thymine bind together to form the A-T base pair. Likewise, guanine and cytosine come together to form the G-C base pair. The bases are joined together by weak hydrogen bonds, and it is this hydrogen bonding that produces DNA's familiar double helix shape. Whatev ...
... DNA to form a base pair. Adenine and thymine bind together to form the A-T base pair. Likewise, guanine and cytosine come together to form the G-C base pair. The bases are joined together by weak hydrogen bonds, and it is this hydrogen bonding that produces DNA's familiar double helix shape. Whatev ...
Nucleic acids
... Recall that the nucleus is a small spherical, dense body in a cell. It is often called the "control center" because it controls all the activities of the cell including cell reproduction, and heredity. Chromosomes are microscopic, threadlike strands composed of the chemical DNA (short for deoxyribon ...
... Recall that the nucleus is a small spherical, dense body in a cell. It is often called the "control center" because it controls all the activities of the cell including cell reproduction, and heredity. Chromosomes are microscopic, threadlike strands composed of the chemical DNA (short for deoxyribon ...
Chapter 9
... This proved that the capsule did not cause the disease, but what did? Griffith then mixed the R strain bacteria with the heat-killed S strain. What do you ...
... This proved that the capsule did not cause the disease, but what did? Griffith then mixed the R strain bacteria with the heat-killed S strain. What do you ...
Get it now - Wichita State University
... As you know, the DNA molecule can be compared with a zipper which can be opened up to allow replication and transcription. Scientist have found that there are several bacterial proteins called enzymes, or, more specifically, restriction enzymes, that have the ability to cut both strands of the DNA m ...
... As you know, the DNA molecule can be compared with a zipper which can be opened up to allow replication and transcription. Scientist have found that there are several bacterial proteins called enzymes, or, more specifically, restriction enzymes, that have the ability to cut both strands of the DNA m ...
DNA - The Double Helix
... Recall that the nucleus is a small spherical, dense body in a cell. It is often called the "control center" because it controls all the activities of the cell including cell reproduction, and heredity. Chromosomes are microscopic, threadlike strands composed of the chemical DNA (short for deoxyribon ...
... Recall that the nucleus is a small spherical, dense body in a cell. It is often called the "control center" because it controls all the activities of the cell including cell reproduction, and heredity. Chromosomes are microscopic, threadlike strands composed of the chemical DNA (short for deoxyribon ...
Matching (2 pts ea)
... 24. What acts as the template in DNA replication? 25. What is a replication fork? 26. Know the function of the following enzymes: topoisomerase, helicase, polymerase, nuclease, primase 28. What is Okazaki fragment? 29. ____________________ are joined to replicating strands of DNA by ________________ ...
... 24. What acts as the template in DNA replication? 25. What is a replication fork? 26. Know the function of the following enzymes: topoisomerase, helicase, polymerase, nuclease, primase 28. What is Okazaki fragment? 29. ____________________ are joined to replicating strands of DNA by ________________ ...
DNA PROFILING
... A technique used by scientists to distinguish between individuals of the same species using only samples of their DNA ...
... A technique used by scientists to distinguish between individuals of the same species using only samples of their DNA ...
DNA Extraction from …
... • The process of extracting DNA from a cell is the first step for many laboratory procedures in biotechnology. • The scientist must be able to separate DNA from the unwanted substances of the cell gently enough so that the DNA ...
... • The process of extracting DNA from a cell is the first step for many laboratory procedures in biotechnology. • The scientist must be able to separate DNA from the unwanted substances of the cell gently enough so that the DNA ...
DNA the Genetic Material
... • DNA primase -creates a short RNA primer complementary to a DNA template; • DNA helicase, which unwinds the helix DNA polymerase, which then synthesizes new DNA by adding nucleotides to the growing strands; and DNA ligase, which creates phosphodiester bonds between adjacent Okazaki fragments. (pp. ...
... • DNA primase -creates a short RNA primer complementary to a DNA template; • DNA helicase, which unwinds the helix DNA polymerase, which then synthesizes new DNA by adding nucleotides to the growing strands; and DNA ligase, which creates phosphodiester bonds between adjacent Okazaki fragments. (pp. ...
unit 4 study guide
... Know the differences between DNA and RNA Know the structure of DNA and RNA Know Protein Synthesis 1. Transcription 2. M-RNA Processing 3. Translation Know DNA Replication Know all about DNA, mRNA, and tRNA; Know diagrams of such molecules and be able to match parts to them. Know the monomers (buildi ...
... Know the differences between DNA and RNA Know the structure of DNA and RNA Know Protein Synthesis 1. Transcription 2. M-RNA Processing 3. Translation Know DNA Replication Know all about DNA, mRNA, and tRNA; Know diagrams of such molecules and be able to match parts to them. Know the monomers (buildi ...
DNA - The Double Helix, Coloring Worksheet
... The image showing replication is similar to the DNA and mRNA coloring. Note the nucleotides are shown as their 3 parts – sugar (blue), phosphate (pink) and one of the four bases (color codes are above). Color the replication model on the second page. Notice that several nucleotides are floating arou ...
... The image showing replication is similar to the DNA and mRNA coloring. Note the nucleotides are shown as their 3 parts – sugar (blue), phosphate (pink) and one of the four bases (color codes are above). Color the replication model on the second page. Notice that several nucleotides are floating arou ...
Gene Technology Study Guide KEY
... DNA ligase: Joins pieces of DNA together (glue) What are sticky ends and what is their importance? Sticky ends are the overhang of nucleotides that result when a restriction enzyme cuts DNA. Their importance is that this allows for DNA from other organisms to join this genome in order to make ...
... DNA ligase: Joins pieces of DNA together (glue) What are sticky ends and what is their importance? Sticky ends are the overhang of nucleotides that result when a restriction enzyme cuts DNA. Their importance is that this allows for DNA from other organisms to join this genome in order to make ...
Chapter 4 • Lesson 20
... A molecule of DNA can be quite long. The nucleus of a single human cell contains more than 1 meter of DNA. To fit inside the nucleus, long sections of DNA are tightly coiled into chromosomes. Chromosomes are structures that contain the genetic information that is passed down from one generation to t ...
... A molecule of DNA can be quite long. The nucleus of a single human cell contains more than 1 meter of DNA. To fit inside the nucleus, long sections of DNA are tightly coiled into chromosomes. Chromosomes are structures that contain the genetic information that is passed down from one generation to t ...
BIOLOGY Wednesday Sub Work
... this strand with no problem, super fast! c. The “Lagging Strand”: i. This is the strand on the original molecule which goes 5’ 3’. ii. This is called the lagging strand because remember DNA polymerase can only lay down nucleotides starting at the 5’ end. That means the Lagging Strand is going in ...
... this strand with no problem, super fast! c. The “Lagging Strand”: i. This is the strand on the original molecule which goes 5’ 3’. ii. This is called the lagging strand because remember DNA polymerase can only lay down nucleotides starting at the 5’ end. That means the Lagging Strand is going in ...
DNA
... double helix, which is like a twisted ladder. The sides of the ladder are made of alternating sugar and phosphate molecules. The sugar is deoxyribose. Color all the phosphates pink (one is labeled with a "p"). Color all the deoxyriboses light blue (one is labeled for you with a "D") . The rungs of t ...
... double helix, which is like a twisted ladder. The sides of the ladder are made of alternating sugar and phosphate molecules. The sugar is deoxyribose. Color all the phosphates pink (one is labeled with a "p"). Color all the deoxyriboses light blue (one is labeled for you with a "D") . The rungs of t ...
DNA - The Double Helix
... how? It is the sequence of bases that determine which protein is to be made. The sequence is like a code that we can now interpret. The sequence determines which proteins are made and the proteins determine which activities will be performed. That is how the nucleus is the control center of the cell ...
... how? It is the sequence of bases that determine which protein is to be made. The sequence is like a code that we can now interpret. The sequence determines which proteins are made and the proteins determine which activities will be performed. That is how the nucleus is the control center of the cell ...
DNA Structure and Replication Notes
... • On the ends of the chromosomes in eukaryotes are structures called telomeres that are repeating bases that protect the DNA ...
... • On the ends of the chromosomes in eukaryotes are structures called telomeres that are repeating bases that protect the DNA ...
notes File - selu moodle
... Primase uses RNA and DNA polymerases Telomeres are replicated using telomerase. Uses an internal RNA as a template and NOT the DNA Activity decreases as we age Link between aging and telomerase activity (or telomere length) Is telomerase the fountain of youth or a highway to cancer!?! 14.6 DNA Repai ...
... Primase uses RNA and DNA polymerases Telomeres are replicated using telomerase. Uses an internal RNA as a template and NOT the DNA Activity decreases as we age Link between aging and telomerase activity (or telomere length) Is telomerase the fountain of youth or a highway to cancer!?! 14.6 DNA Repai ...
Chromosome Contact Matrices
... cell types This is very frequent at the subtad level as opposed to the rather infrequent neighboring „super-TAD” rearrangements One needs to define a distance metric on the domain hierarchies to be able to measure the amount of change between conditions ...
... cell types This is very frequent at the subtad level as opposed to the rather infrequent neighboring „super-TAD” rearrangements One needs to define a distance metric on the domain hierarchies to be able to measure the amount of change between conditions ...
Scientist Guide DNA Bracelet Workshop
... Deoxyribonucleic acid (DNA) is a molecule that encodes genetic instructions. These instructions guide the development and functioning of all known living organisms. Similar to the way a builder uses a blueprint to construct a house, cells use DNA to construct an organism. DNA is therefore often cons ...
... Deoxyribonucleic acid (DNA) is a molecule that encodes genetic instructions. These instructions guide the development and functioning of all known living organisms. Similar to the way a builder uses a blueprint to construct a house, cells use DNA to construct an organism. DNA is therefore often cons ...
Genetic Engineering
... A technique used by scientists to distinguish between individuals of the same species using only samples of their _____________ ...
... A technique used by scientists to distinguish between individuals of the same species using only samples of their _____________ ...
DNA repair
DNA repair is a collection of processes by which a cell identifies and corrects damage to the DNA molecules that encode its genome. In human cells, both normal metabolic activities and environmental factors such as UV light and radiation can cause DNA damage, resulting in as many as 1 million individual molecular lesions per cell per day. Many of these lesions cause structural damage to the DNA molecule and can alter or eliminate the cell's ability to transcribe the gene that the affected DNA encodes. Other lesions induce potentially harmful mutations in the cell's genome, which affect the survival of its daughter cells after it undergoes mitosis. As a consequence, the DNA repair process is constantly active as it responds to damage in the DNA structure. When normal repair processes fail, and when cellular apoptosis does not occur, irreparable DNA damage may occur, including double-strand breaks and DNA crosslinkages (interstrand crosslinks or ICLs).The rate of DNA repair is dependent on many factors, including the cell type, the age of the cell, and the extracellular environment. A cell that has accumulated a large amount of DNA damage, or one that no longer effectively repairs damage incurred to its DNA, can enter one of three possible states: an irreversible state of dormancy, known as senescence cell suicide, also known as apoptosis or programmed cell death unregulated cell division, which can lead to the formation of a tumor that is cancerousThe DNA repair ability of a cell is vital to the integrity of its genome and thus to the normal functionality of that organism. Many genes that were initially shown to influence life span have turned out to be involved in DNA damage repair and protection.