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Monarch® DNA Wash Buffer | NEB
Monarch® DNA Wash Buffer | NEB

... The following is a list of Safety Data Sheet (SDS) that apply to this product to help you use it safely. Monarch® DNA Wash Buffer ...
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DNA Replication
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GENETICS: BIOLOGY HSA REVIEW

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... Each cell continually monitors and repairs its genetic material, with over 130 repair enzymes identified in humans. The final error rate is only one per billion nucleotides, so, about 6 mutations per cell division! Replication of Chromosome Ends Limitations in the DNA polymerase problems for the lin ...
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... Background Information: DNA is the basic material that contains the information that is responsible for the way all living organisms physically look and instruction on how to carry out the activities of the cell. We are going to explore the different parts of DNA. READ THIS BEFORE MOVING ON: Before ...
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... Both processes involve making a copy of the DNA code in the nucleus. Transcription makes a copy of the code by producing mRNA with RNA nucleotides. Whereas DNA replication uses DNA nucleotides to produce an identical copy. DNA replication uses both sides of the DNA, whereas transcription only uses t ...
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DNA repair



DNA repair is a collection of processes by which a cell identifies and corrects damage to the DNA molecules that encode its genome. In human cells, both normal metabolic activities and environmental factors such as UV light and radiation can cause DNA damage, resulting in as many as 1 million individual molecular lesions per cell per day. Many of these lesions cause structural damage to the DNA molecule and can alter or eliminate the cell's ability to transcribe the gene that the affected DNA encodes. Other lesions induce potentially harmful mutations in the cell's genome, which affect the survival of its daughter cells after it undergoes mitosis. As a consequence, the DNA repair process is constantly active as it responds to damage in the DNA structure. When normal repair processes fail, and when cellular apoptosis does not occur, irreparable DNA damage may occur, including double-strand breaks and DNA crosslinkages (interstrand crosslinks or ICLs).The rate of DNA repair is dependent on many factors, including the cell type, the age of the cell, and the extracellular environment. A cell that has accumulated a large amount of DNA damage, or one that no longer effectively repairs damage incurred to its DNA, can enter one of three possible states: an irreversible state of dormancy, known as senescence cell suicide, also known as apoptosis or programmed cell death unregulated cell division, which can lead to the formation of a tumor that is cancerousThe DNA repair ability of a cell is vital to the integrity of its genome and thus to the normal functionality of that organism. Many genes that were initially shown to influence life span have turned out to be involved in DNA damage repair and protection.
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