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DNA
DNA

... than the complimentary strand will be: ________________ Human DNA has 3 billion base pairs.. Less than 1% of our DNA makes us different from one another! ...
DNA
DNA

... 8) The primary DNA repair enzyme is DNA polymerase I but DNA polymersae II can serve as an alternate repair polymerase and can replicate DNA under circumstances in which the template is damaged. 9) DNA topoisomerases relax the supercoils formed beyond the replication fork by introducing a cut in the ...
Chapter 16: The Molecular Basis of Inheritance
Chapter 16: The Molecular Basis of Inheritance

... 1. Summarize the evidence and techniques Watson and Crick used to deduce the doublehelix structure of DNA. Watson and Crick used the X-ray diffraction photo of Franklin to deduce that DNA was a helix 2 nm wide, with nitrogenous bases stacked 0.34 nm apart, and making a full turn every 3.4 nm. Frankl ...
History and Shape of DNA
History and Shape of DNA

... Inside- nitrogen containing bases ...
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GLOSSARY:

... process, cellular material (including DNA) is released. Micropipette - A pipette that measures and injects very small volumes of liquid. Micropipette tip - A disposable funnel fitting to the end of a micropipette. The sterile tips help prevent contamination of DNA and other sensitive reactants. Micr ...
4.1 DNA History - Lincoln County Schools
4.1 DNA History - Lincoln County Schools

... Rosalind Franklin (in the 1950’s) A. She performed X-ray Crystallography on DNA. This picture was extremely important in helping James Watson and Francis Crick develop their model of DNA. (See below) 1. The picture indicates the Double Helix (The picture would be from the view of looking down a stra ...
DNA Replication
DNA Replication

... – DNA polymerase I was discovered in the mid 1950s by Arthur Kornberg (it was originally simply called “DNA polymerase” – DNA polymerase I has three different ...
Answers - MrsPalffysAPBio2013
Answers - MrsPalffysAPBio2013

... •DNA polymerase only adds new nucleotides to the 3’ end of an existing nucleic acid. •First, an RNA primer of ~10 nucleotides is made by primase so that DNA polymerase has something to attach to & can begin constructing a new DNA strand •Therefore, at a replication fork, the complementary strands of ...
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01 - Denton ISD

... __________ brings amino acids from the cytoplasm to a ribosome to help make the growing protein. __________ forms part of ribosomes. __________ is an intermediate message that is translated to form a protein. MAIN IDEA: The transcription process is similar to replication. ...
The structure of nucleotides Section 11.1 Summary – pages 281
The structure of nucleotides Section 11.1 Summary – pages 281

... The structure of DNA • In 1953, Watson and Crick proposed that DNA is made of two chains of nucleotides held together by nitrogenous bases. • Watson and Crick also proposed that DNA is shaped like a long zipper that is twisted into a coil like a spring. • Because DNA is composed of two strands twis ...
DNA: Hereditary Molecules of Life
DNA: Hereditary Molecules of Life

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DNA Overview PowerPoint
DNA Overview PowerPoint

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Class Presentation Questions for CH 12 Part 1(Sections 1-2-3).
Class Presentation Questions for CH 12 Part 1(Sections 1-2-3).

... 1. The double helix structure explains how DNA can be copied but does not explain _____________________________. 2. ____________ are coded DNA instructions that control the production of proteins within the cell. 3. The process of decoding DNA involves a second nucleic acid known as ________________ ...
ch. 16 Molecular Basis of Inheritance
ch. 16 Molecular Basis of Inheritance

... • Griffith-Avery Experiment—DNA can ...
Molecular Genetics
Molecular Genetics

... • DNA consists of two antiparallel strands of nucleotides • Bases of one strand are paired with bases in the other strand • Nitrogenous base pairs are arranged above each other, perpendicular to the axis of the molecule • A Purine always bonded to a Pyrimidine ▫ Adenine with Thymine ▫ Guanine with C ...
Chapter 16
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... 7. Briefly diagram the double helix structure of DNA. Include: a. At least one A,T,C,G per strand. b. Labeled phosphates, deoxyribose, phosphodiester bonds, and the correct number of hydrogen bonds per base pair. c. Make sure to show the anti-parallel orientation of both strands. DNA Replication and ...
DNA From the Beginning WEBQUEST
DNA From the Beginning WEBQUEST

... Go to www.dnaftb.org and then complete the following web quest: Answer your questions on that document. Print when finished or email to Mrs. Berthelot: [email protected] Click on the link “Molecules of Genetics”, then click on Lesson 15 (DNA and proteins are key molecules of the cell nucleus) and ...
DNA - Canyon ISD
DNA - Canyon ISD

... • Hydrogen bonds are ______ but there are millions and millions of them in a ...
DNA Flipbook Objective: You will create an informational Flipbook
DNA Flipbook Objective: You will create an informational Flipbook

... _____ Show complimentary base pairing _____ Draw and label one nucleotide. (See picture to right) _____ Show which bases are purine and which are pyrimidine? _____ Identify the molecules that makeup the backbone of DNA. _____ What is the shape of DNA called? _____ Draw a double helix DNA molecule ...
DNA Review Packet
DNA Review Packet

... DNA Replication (Review your notes on “replication” to help you answer these questions.) 7. Put the pictures of DNA replication in order by placing a 1, 2, or 3 on the line above the picture. 8. Describe what is happening on the lines below the picture. Be sure to include the names of any enzyme inv ...
12 Week CCA Test Review
12 Week CCA Test Review

... E. What effect do you think this would have on the production of the protein? ...
DNA Structure and Replication Integrated Science 4
DNA Structure and Replication Integrated Science 4

... The X pattern produced suggested DNA was composed of two strands twisted around each other with nitrogenous bases oriented toward the center of the molecule. 7. Following Rosalind Franklin’s work, James Watson and Francis Crick established the structure of DNA. Describe their work, including the rel ...
DNA Replication
DNA Replication

... C) The replisome needs to have primase activity to make RNA primers for the  lagging strand D) Proofreading activity is required for the leading strand, but not the lagging  strand. 5. Which of these activit(ies) is the last one in the process of lagging strand  synthesis? A) Ligase B) Polymerase C) ...
DNA Replication
DNA Replication

... C) The replisome needs to have primase activity to make RNA primers for the lagging strand D) Proofreading activity is required for the leading strand, but not the lagging strand. 5. Which of these activit(ies) is the last one in the process of lagging strand synthesis? A) Ligase B) Polymerase C) 5’ ...
DNArepl2
DNArepl2

... RF-C is a five-subunit complex All subunits are related in sequence and have ATP binding motifs ATP hydrolysis by RF-C is associated with the loading of PCNA RF-C is the functional homolog of the clamp-loader  complex ...
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Eukaryotic DNA replication



Eukaryotic DNA replication is a conserved mechanism that restricts DNA replication to only once per cell cycle. Eukaryotic DNA replication of chromosomal DNA is central for the duplication of a cell and is necessary for the maintenance of the eukaryotic genome.DNA replication is the action of DNA polymerases synthesizing a DNA strand complementary to the original template strand. To synthesize DNA, the double-stranded DNA is unwound by DNA helicases ahead of polymerases, forming a replication fork containing two single-stranded templates. Replication processes permit the copying of a single DNA double helix into two DNA helices, which are divided into the daughter cells at mitosis. The major enzymatic functions carried out at the replication fork are well conserved from prokaryotes to eukaryotes, but the replication machinery in eukaryotic DNA replication is a much larger complex, coordinating many proteins at the site of replication, forming the replisome.The replisome is responsible for copying the entirety of genomic DNA in each proliferative cell. This process allows for the high-fidelity passage of hereditary/genetic information from parental cell to daughter cell and is thus essential to all organisms. Much of the cell cycle is built around ensuring that DNA replication occurs without errors.In G1 phase of the cell cycle, many of the DNA replication regulatory processes are initiated. In eukaryotes, the vast majority of DNA synthesis occurs during S phase of the cell cycle, and the entire genome must be unwound and duplicated to form two daughter copies. During G2, any damaged DNA or replication errors are corrected. Finally, one copy of the genomes is segregated to each daughter cell at mitosis or M phase. These daughter copies each contain one strand from the parental duplex DNA and one nascent antiparallel strand.This mechanism is conserved from prokaryotes to eukaryotes and is known as semiconservative DNA replication. The process of semiconservative replication for the site of DNA replication is a fork-like DNA structure, the replication fork, where the DNA helix is open, or unwound, exposing unpaired DNA nucleotides for recognition and base pairing for the incorporationof free nucleotides into double-stranded DNA.
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