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DNA history and structure KS
DNA history and structure KS

... • Pyrimidines (T and C) have a single ring structure. • Purines (A and G) have a double ring structure. ...
CH 16 Vocab
CH 16 Vocab

... A dense region of DNA in a prokaryotic cell. Nucleosome The basic, bead-like unit of DNA packing in eukaryotes, consisting of a segment of DNA wound around a protein core composed of two copies of each of four types of histone. Nucleotide excision repair ...
DNA History, Structure, and Replication – Part 2
DNA History, Structure, and Replication – Part 2

... 3. The radioactive viruses where then exposed to bacteria. The viruses infected the bacteria. In the radioactive Sulfur container, the radioactive sulfur did NOT enter the bacteria. It remained outside the bacteria. When the viruses reproduced inside the bacteria, the reproduced viruses that came ou ...
DNA & DNA Replication
DNA & DNA Replication

... Other enzymes needed to excise (remove) the primers Nuclease – removes the RNA primer nucleotide by nucleotide  Repair polymerase – replaces RNA with DNA  DNA ligase – seals the sugar-phosphate backbone by creating phosphodiester bond ...
I. DNA - Humble ISD
I. DNA - Humble ISD

... bacteria with living bacteria that did not cause disease. Discovered ability of bacteria to cause disease could be passed from one bacteria to another. Griffith called this _transformation___________. _Avery_____ later identified this “transforming substance” as _DNA______. 2. Hershey and Chase - 19 ...
Discovering DNA: Structure and Replication
Discovering DNA: Structure and Replication

... DNA Replication • DNA Replication occurs in four basic steps: – Step 1 – Helicase unzips the strand of DNA by breaking the weak hydrogen bonds between base pairs. – Step 2 – DNA polymerase inserts the appropriate bases. – Step 3 – A new sugar-phosphate backbone is built. – Step 4 – The sequence is ...
DNA - California State University Channel Islands
DNA - California State University Channel Islands

... Introduction.-Studies of bacterial transformation and bacteriaphage infection'-‘ strongly indicate that deoxyribonucleic acid (DNA) can carry and transmit hereditary information and can direct its own replication. Hypotheses for the mechanism of DNA replication differ in the predictions they make co ...
DNA Replication
DNA Replication

... The process of making a copy of DNA is called DNA replication. The process can be broken down into three steps. Step 1: Before replication can begin, the double helix must unwind. This is accomplished by enzymes called DNA helicases, which open up the double helix by breaking the hydrogen bonds that ...
DNA: The Genetic Material
DNA: The Genetic Material

... DNA repair mechanisms can be: • specific – targeting a particular type of DNA damage • photorepair of thymine dimers • non-specific – able to repair many different kinds of DNA damage • excision repair to correct damaged or mismatched nitrogenous bases ...
SBI4U-Molecular Genetics Molecular Genetics Unit Test –Multiple
SBI4U-Molecular Genetics Molecular Genetics Unit Test –Multiple

... 11) The number of nitrogenous bases codes by 9 amino acids would be a) 27 b) 9 c) 3 d) 18 e) Too little information provided 12) In Huntington’s disease, CAG repeats occur more frequently than in people without the disease. The results in many more additional amino acids of the same type added in th ...
Ch 16 DNA structure and replication powerpoint
Ch 16 DNA structure and replication powerpoint

... B. DNA strands are antiparallel, continuous synthesis of both DNA strands is not possible 1. chains have direction - one end (5') has a free phosphate, the other (3') a free hydroxyl (-OH) 2. double stranded molecule, the two strands are opposite, one is 3' to 5' and the other is 5' to 3' antipara ...
No Slide Title
No Slide Title

... RF-C is a five-subunit complex All subunits are related in sequence and have ATP binding motifs ATP hydrolysis by RF-C is associated with the loading of PCNA RF-C is the functional homolog of the clamp-loader  complex ...
History of DNA
History of DNA

... Why is deoxyribose called a pentose sugar? ...
DNA Replication
DNA Replication

... base pairs (A-T & C-G) -- Applied Chargaff’s rules c. Base pairs (steps) are held together by weak hydrogen bonds d. Sequence (order) of nitrogen bases determines the genetic instructions / “genetic code” of organism. ...
DNA (Deoxyribonucleic Acid)
DNA (Deoxyribonucleic Acid)

... • DNA is copied (replicated) during the_________ stage of the cell cycle. S nucleus of the cell. • This occurs in the __________ • This process is called- ...
DNA, RNA, and Protein Synthesis: Information to
DNA, RNA, and Protein Synthesis: Information to

... d. DNA aminopeptidase 8. What is the name of the enzyme binds sections of DNA together after replication? a. DNA polymerase b. DNA helicase c. DNA ligase d. DNA aminopeptidase 9. When an error in replication occurs, it is called a __________. a. mutation b. duplication c. natural selection d. adapt ...
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DNA Structure

... Think – Pair - Share  Look at the picture and try to figure out what ...
Chapter 12 Practice Test
Chapter 12 Practice Test

... 17. _________________________ are weak bonds that hold the two strands of DNA together, but also allow the DNA to separate and replicate. 18. Chromatin contains proteins called ______________________. 19. DNA replication is carried out by a series of _____________________. 20. The tips of chromosome ...
HRW BIO CRF Ch 09_p01-58
HRW BIO CRF Ch 09_p01-58

... sequence of nitrogen bases on one strand determines the sequence of nitrogen bases on the other strand. This means that DNA is made of two complementary strands of DNA. 18. Each nucleotide is made up of three parts: a phosphate group, a fivecarbon sugar (deoxyribose), and a nitrogen base. 19. The ha ...
DNA Replication Complex
DNA Replication Complex

... In linear DNA, replication cannot occur on the 5’ ends of daughter DNA strands. This is because DNA polymerase can only add nucleotides to the 3’ end. Because of this, DNA strands would be made unevenly with progressively shorter ends. To combat this, organisms with linear DNA (Eukaryotes), have str ...
Reading GuideDNAto protein(CH7)
Reading GuideDNAto protein(CH7)

... So what exactly is the chemical composition of DNA? It is composed of a phosphate-sugar backbone, the sugar and phosphate are covalently bonded in alternating subunits. The sugar found in the structure of DNA is deoxyribose and it is here that the nitrogenous bases bind. In DNA, these nitrogenous ba ...
14. Central Dogma practice
14. Central Dogma practice

... To understand the Central Dogma and be able to use this knowledge in biology requires that you first learn to manipulate the DNA and RNA bases through the processes of replication, transcription and translation “on paper”. After you have a thorough understanding you can proceed to more challenging a ...
DNA the Genetic Material
DNA the Genetic Material

... • DNA primase -creates a short RNA primer complementary to a DNA template; • DNA helicase, which unwinds the helix DNA polymerase, which then synthesizes new DNA by adding nucleotides to the growing strands; and DNA ligase, which creates phosphodiester bonds between adjacent Okazaki fragments. (pp. ...
Ch.22Pt.2_000
Ch.22Pt.2_000

... function of different types of nucleic acids •Draw the basic structure of nucleosides and nucleotides •Explain the primary structure of nucleic acids and compare it to protein structure •Describe the structural properties of the DNA double helix •Draw the steps involved in DNA replication •Compare & ...
DNA structure
DNA structure

... What types of bases are found in DNA and RNA? • Purines (found in RNA & DNA) – Adenine – Guanine ...
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Eukaryotic DNA replication



Eukaryotic DNA replication is a conserved mechanism that restricts DNA replication to only once per cell cycle. Eukaryotic DNA replication of chromosomal DNA is central for the duplication of a cell and is necessary for the maintenance of the eukaryotic genome.DNA replication is the action of DNA polymerases synthesizing a DNA strand complementary to the original template strand. To synthesize DNA, the double-stranded DNA is unwound by DNA helicases ahead of polymerases, forming a replication fork containing two single-stranded templates. Replication processes permit the copying of a single DNA double helix into two DNA helices, which are divided into the daughter cells at mitosis. The major enzymatic functions carried out at the replication fork are well conserved from prokaryotes to eukaryotes, but the replication machinery in eukaryotic DNA replication is a much larger complex, coordinating many proteins at the site of replication, forming the replisome.The replisome is responsible for copying the entirety of genomic DNA in each proliferative cell. This process allows for the high-fidelity passage of hereditary/genetic information from parental cell to daughter cell and is thus essential to all organisms. Much of the cell cycle is built around ensuring that DNA replication occurs without errors.In G1 phase of the cell cycle, many of the DNA replication regulatory processes are initiated. In eukaryotes, the vast majority of DNA synthesis occurs during S phase of the cell cycle, and the entire genome must be unwound and duplicated to form two daughter copies. During G2, any damaged DNA or replication errors are corrected. Finally, one copy of the genomes is segregated to each daughter cell at mitosis or M phase. These daughter copies each contain one strand from the parental duplex DNA and one nascent antiparallel strand.This mechanism is conserved from prokaryotes to eukaryotes and is known as semiconservative DNA replication. The process of semiconservative replication for the site of DNA replication is a fork-like DNA structure, the replication fork, where the DNA helix is open, or unwound, exposing unpaired DNA nucleotides for recognition and base pairing for the incorporationof free nucleotides into double-stranded DNA.
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