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lecture notes
lecture notes

... homeologous sequences. (=similar but not identical sequences) interferes with formation of Holiday intermediate Oxidative damage oxidants from normal metabolism- usually fairly efficient conversion of O2 to H20, but some of the reactive intermediates are inevitable byproducts (all organisms). OH-red ...
PROVING THAT DNA REPLICATION IS SEMICONSERVATIVE
PROVING THAT DNA REPLICATION IS SEMICONSERVATIVE

... based on their double-helical model of DNA, that replication occurs in a semiconservative fashion. That is, the double helix unwinds, the original parental DNA stands serve as templates to direct the synthesis of the progeny strand, and each of the replicated DNA duplexes contains one old (parental) ...
Large molecules: Carbohydrates,DNA to Protein
Large molecules: Carbohydrates,DNA to Protein

... • Sequences of nucleotides can form hydrogen bonding between their nitrogenous bases. • The base pairing is complementary: At each position where a purine is found on one strand, a pyrimidine is found on the other. • Purines have a double-ring structure. Pyrimidines have one ring. ...
Chapter 12
Chapter 12

... 3. Loose nitrogen bases are present in the nucleus of the cell. The free nitrogen bases join with their complimentary nitrogen bases that are exposed on the open strand of DNA. ...
The Structure of DNA
The Structure of DNA

... •Adenine & Guanine are called purines because they have a double ring structure. • Thymine & Cytosine are called pyrimidines because they have a single ring structure. ...
Central Dogma Lecture Central_Dogma_Notes
Central Dogma Lecture Central_Dogma_Notes

... A new strand of DNA is formed along each of the open strands. Two complete and identical DNA helices are created. Cell division can now occur with the newly created DNA strand. ...
PowerPoint Notes on Chapter 9 - DNA: The Genetic Material (Video
PowerPoint Notes on Chapter 9 - DNA: The Genetic Material (Video

... role. This proofreading reduces errors in DNA replication to about one error per 1 billion nucleotides. The Rate of Replication Replication does not begin at one end of the DNA molecule and end at the other. The circular DNA molecules found in prokaryotes usually have two replication forks that begi ...
DNA str, Replication, Damage & Repair
DNA str, Replication, Damage & Repair

... Cytosine The bases form weak hydrogen bonds ...
DNA - The Double Helix
DNA - The Double Helix

... Every cell in your body has the same "blueprint" or the same DNA. . Like the blueprints of a house tell the builders how to construct a house, the DNA "blueprint" tells the cell how to build the organism. But how can a heart be so different from a brain if all the cells contain the same instructions ...
Chapter 16: DNA: The Genetic Material
Chapter 16: DNA: The Genetic Material

... one strand being synthesized, the leading strand, has its 3’ end at the fork; thus, its synthesis can proceed continuously, in the direction that the fork moves ...
DNA WebQuest
DNA WebQuest

... come to the game.; Click on organism #1 and match the base pairs as fast as you can! It is hard. Click Next and then click on each organism until you identify the one that belongs to chromosome #1; continue playing the game with the other two chromosomes, filling in the chart below. ...
12.1 and 12.2 Fill
12.1 and 12.2 Fill

...  During most of the cell cycle, DNA is unwound, so that the chromosomes are ______ visible.  During mitosis, the tightly packed chromosomes form in order to move more efficiently.  Before cell division, DNA must make a copy of itself during S phase of __________________.  This process is called ...
DNA to Protein - Louisiana Believes
DNA to Protein - Louisiana Believes

... two intertwined strands have to be separated. The strands can’t be separated simply by pulling them apart; they must be broken to relieve the double helix thermodynamic strain. This allows a point of rotation as the two halves of the DNA are separated by weakening the hydrogen bonds. The double stra ...
Question_Bank_5th_Sem
Question_Bank_5th_Sem

... make copies for daughter cells. Which statement describes the DNA in daughter cells? A. The double helix in one daughter cell consists of two strands that were originally in the parent cell, while the double helix in the other daughter cell consists of two newly made strands. B. The two strands of t ...
DNA Replication - inetTeacher.com
DNA Replication - inetTeacher.com

... big to leave through the nuclear pores. If DNA was not copied the code could not be transferred to the place it can be created. ...
DNA replication
DNA replication

... • Each human cell contains 46 chromosomes (6 to 9 feet of DNA) • Your body contains 75-100 trillion of cells. • All of your DNA (when uncoiled and tied ...
DNA replication
DNA replication

... • Each human cell contains 46 chromosomes (6 to 9 feet of DNA) • Your body contains 75-100 trillion of cells. • All of your DNA (when uncoiled and tied ...
View PDF - Mvla.net
View PDF - Mvla.net

... DNA replicates during mitosis so that C---G both new cells will have the correct DNA. T---A 2. When does replication occur? A---T Replication happens during the S phase G---C of the cell cycle (during interphase). A---T 3. Describe how replication works. Enzymes unzip DNA and complementary G---C C-- ...
Biology: DNA Unit Review
Biology: DNA Unit Review

... d. Name the enzyme that will reconnect the DNA bases in area B. e. After filling in the correct DNA bases in area B, are the two strands of DNA identical? ...
DNA Replication
DNA Replication

... In prokaryotes there are ONLY TWO replication forks and they move in opposite directions until they meet Prokaryotic vs Eukaryotic Replication In eukaryotes DNA polymerase adds new nucleotides at 50/second ...
Questions 4
Questions 4

... Identify the choice that best completes the statement or answers the question. ____ 1. Bacteria are capable of __________ transmission—the transfer of genetic information from one cell to another. a. vertical d. transformation b. horizontal e. pseudogene c. recombination ____ 2. The smallest cellula ...
Molecular Bio Questions1
Molecular Bio Questions1

... Identify the choice that best completes the statement or answers the question. ____ 1. Bacteria are capable of __________ transmission—the transfer of genetic information from one cell to another. a. vertical d. transformation b. horizontal e. pseudogene c. recombination ____ 2. The smallest cellula ...
DNA Replication Computer Gizmo
DNA Replication Computer Gizmo

... 11. What 2 molecules make up the backbone (or sides) of the DNA molecule? _____________________________ and _______________________________ 12. What molecules make up the rungs (or middle) of the DNA molecule? ...
DNA Structure DNA Structure
DNA Structure DNA Structure

... DNA polymerase III can only add new nucleotides to the 3’ end of an existing strand, there is no way to complete the final segment of the lagging strand located at each end of a linear DNA molecule.  As a result, linear DNA molecules gets shorter and shorter with each round of replication: ...
No Slide Title - Cloudfront.net
No Slide Title - Cloudfront.net

... 1) DNA = two strands of nucleotides twisted into a double helix 2) Helixes run antiparallel to each other (in opposite directions) – Watson’s discovery ...
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Eukaryotic DNA replication



Eukaryotic DNA replication is a conserved mechanism that restricts DNA replication to only once per cell cycle. Eukaryotic DNA replication of chromosomal DNA is central for the duplication of a cell and is necessary for the maintenance of the eukaryotic genome.DNA replication is the action of DNA polymerases synthesizing a DNA strand complementary to the original template strand. To synthesize DNA, the double-stranded DNA is unwound by DNA helicases ahead of polymerases, forming a replication fork containing two single-stranded templates. Replication processes permit the copying of a single DNA double helix into two DNA helices, which are divided into the daughter cells at mitosis. The major enzymatic functions carried out at the replication fork are well conserved from prokaryotes to eukaryotes, but the replication machinery in eukaryotic DNA replication is a much larger complex, coordinating many proteins at the site of replication, forming the replisome.The replisome is responsible for copying the entirety of genomic DNA in each proliferative cell. This process allows for the high-fidelity passage of hereditary/genetic information from parental cell to daughter cell and is thus essential to all organisms. Much of the cell cycle is built around ensuring that DNA replication occurs without errors.In G1 phase of the cell cycle, many of the DNA replication regulatory processes are initiated. In eukaryotes, the vast majority of DNA synthesis occurs during S phase of the cell cycle, and the entire genome must be unwound and duplicated to form two daughter copies. During G2, any damaged DNA or replication errors are corrected. Finally, one copy of the genomes is segregated to each daughter cell at mitosis or M phase. These daughter copies each contain one strand from the parental duplex DNA and one nascent antiparallel strand.This mechanism is conserved from prokaryotes to eukaryotes and is known as semiconservative DNA replication. The process of semiconservative replication for the site of DNA replication is a fork-like DNA structure, the replication fork, where the DNA helix is open, or unwound, exposing unpaired DNA nucleotides for recognition and base pairing for the incorporationof free nucleotides into double-stranded DNA.
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