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12–1 DNA - Biology Junction
12–1 DNA - Biology Junction

... Transformation Griffith called this process transformation because one strain of bacteria (the harmless strain) had changed permanently into another (the disease-causing strain). ...
Single cell genome analysis of an uncultured heterotrophic
Single cell genome analysis of an uncultured heterotrophic

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RegulomeDB - Ritchie Lab
RegulomeDB - Ritchie Lab

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... nonexpected point-mutations are present. A pointmutation at the site of hybridization with the probes will give rise to unstable binding of both probes, and a point-mutation at the hybridization site of one of the primers might make the amplification of this allele inefficient. In both cases only th ...
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... All rights reserved ...
GCAT-SEEK Workshop - Prokaryotic Genomics Module – Jeff
GCAT-SEEK Workshop - Prokaryotic Genomics Module – Jeff

... DNA sample, and ideally to sequence the PCR product via the Sanger method to confirm that the DNA is from the expected organism. We don’t need to spend $200 to sequence E.coli again! Design of oligonucleotide primers to amplify and sequence ribosomal RNA genes. The 16S rRNA gene is present in all Ba ...
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Slide 1
Slide 1

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... paternal X, the paternal Y, and a maternal X chromosome). Those pseudoautosomal loci distal to U7 would be present in only two copies (one from the paternal Y chromosome and one from a maternal X chromosome). We therefore determined the copy number of several pseudoautosomal loci in CONlOl. To obtai ...
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... Nucleic acids mass fraction of common mass in human body is small, remarkably smaller as 1%, because in each cell nucleus present just one DNA copy of molecule. For other molecules of cells copy numbers are millions and billions identical copies. Each cell can have just one active encoded gene set a ...
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LECTURE 10.1 DNA

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DNA and Gene Expression (chaps 12-15)
DNA and Gene Expression (chaps 12-15)

... 63 To avoid the introduction of introns into the vector, a __________ copy of mature mRNA is made, using the enzyme __________. A. cDNA; DNA ligase B. cDNA; reverse transcriptase C. sDNA; reverse transcriptase D. sDNA; RNA polymerase E. cDNA; DNA polymerase ...
myDNA
myDNA

... •these patterns can specifically identify individual people DNA Fingerprinting is a method where: •a person’s genetic traits, genes, are used to •make specific strings of DNA letters that •are cut into patterns of shorter strings separated by length •these banding patterns can identify a unique huma ...
SCI 30 UA CH 2.3 DNA - Fort Saskatchewan High
SCI 30 UA CH 2.3 DNA - Fort Saskatchewan High

... vice versa (C-G or G-C). As a result of the specific bonding between bases, the DNA molecule is comprised of two long chains of nucleotides with bases of one chain paired up with another chain containing complementary bases. For example, if the base pairs on one side of the molecule are ACTGTTA, the ...
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Microsatellite



A microsatellite is a tract of repetitive DNA in which certain DNA motifs (ranging in length from 2–5 base pairs) are repeated, typically 5-50 times. Microsatellites occur at thousands of locations in the human genome and they are notable for their high mutation rate and high diversity in the population. Microsatellites and their longer cousins, the minisatellites, together are classified as VNTR (variable number of tandem repeats) DNA. The name ""satellite"" refers to the early observation that centrifugation of genomic DNA in a test tube separates a prominent layer of bulk DNA from accompanying ""satellite"" layers of repetitive DNA. Microsatellites are often referred to as short tandem repeats (STRs) by forensic geneticists, or as simple sequence repeats (SSRs) by plant geneticists.They are widely used for DNA profiling in kinship analysis and in forensic identification. They are also used in genetic linkage analysis/marker assisted selection to locate a gene or a mutation responsible for a given trait or disease.
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