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DNA
DNA

... DNA double helix •Two separate strands •Antiparellel (5’3’ direction) •Base pairing: hydrogen bonding that holds two strands together •Complementary (sequence) • Sugar-phosphate backbones (negatively charged): outside • Base pairs (stack one above the other): inside ...
Nucleic Acids & Protein Synthesis
Nucleic Acids & Protein Synthesis

... A. The genetic code is the same for nearly all organisms. B. The genetic code does not dictate the amino acid sequence of proteins. C. A mutation in one base will always have a physical effect on the resulting protein. D. A mutation in one base could have absolutely no physical effect on the resulti ...
Teacher Notes - 3D Molecular Designs
Teacher Notes - 3D Molecular Designs

... Note: You may elect to include the following interesting note: If one tRNA anticodon variety existed for each mRNA codon specifying an amino acid, there would be 61 tRNAs. In fact, there are only about 45, implying rules for base pairing between the third nucleotide base of the mRNA codon and the co ...
Genetic Code
Genetic Code

... (pg. 175, Figure 17) The mice ran away. ...
Document
Document

... The Race to Replicate DNA • Two teams: A and B • Individually, each team member will run to the board to add a nucleotide to the “unzipped” strand of DNA. • The first team to finish base-pairing their DNA correctly will win the game. ...
Quick Guide for Forensic DNA Fingerprinting Kit BioRad Student
Quick Guide for Forensic DNA Fingerprinting Kit BioRad Student

... II. Gel Electrophoresis 1. Prepare 50 ml of an 0.8% agarose gel in 1XTBE. The instructor may add DNA stain at this point. Let solidify. 2. Remove digested DNA samples from the freezer. Pulse spin to bring all of liquid into bottom of tube. 3. Place gel in the electrophoresis apparatus. Fill the elec ...
History of DNA - WordPress.com
History of DNA - WordPress.com

... The “parent” molecule has two complementary strands of DNA. Each is base paired by hydrogen bonding with its specific partner: A with T G with C ...
Chapter 12: Nucleotides and Nucleic Acids
Chapter 12: Nucleotides and Nucleic Acids

... determined that all the basic rules of protein and nucleic acid structure and synthesis are the same in Oz as they are on earth, with only two apparent exceptions. First, in Oz, only 12 different amino acids could be detected in protein samples (Gly, Pro, Leu, Lys, Arg, Phe, Tyr, Glu, Ser, Cys, Gln, ...
TABLE OF CONTENTS - Yale School of Medicine
TABLE OF CONTENTS - Yale School of Medicine

... and then have children say this). DNA is referred to as the blueprint for life. Show model of DNA and ask what kind of structure is this? Helix. The building blocks of DNA are deoxyribonucleotides. Deoxyribonucleotides are sugar molecules (deoxyribose) connected to a phosphate group and a base. Thou ...
DNA, RNA and Protein Synthesis
DNA, RNA and Protein Synthesis

...  In 1950s a James Watson teamed up with Francis Crick to try and determine the structure of DNA.  By 1953 they had put together a model for the structure of DNA.  They proposed that DNA is made up of 2 chains that wrap around each other in the shape of a double helix, similar to that of a winding ...
DNA, RNA & PROTEIN SYNTHESIS
DNA, RNA & PROTEIN SYNTHESIS

... Nucleotides found in the surrounding nucleoplasm join to their base pair by enzymes known as POLYMERASES. Hydrogen bonds form between the bases. When each of the strands is remade, two IDENTICAL strands are made with ONE OLD strand and ONE NEW strand = SEMICONSERVATIVE REPLICATION ...
Structure, replication and repair of DNA
Structure, replication and repair of DNA

... Rosalind Franklin (she would have won if she had not been socially isolated)  Chemical make up had been known for 30 years, but not the three-dimensional structure, which would give a clue as to how it worked.  Nucleotides - sugar-phosphate backbone and nitrogenous bases. ...
inv3DNA - Empidonax-hommondii10-11
inv3DNA - Empidonax-hommondii10-11

... beaker. He was then able to separate the nuclei from the cytoplasm. Once that happened, Miescher applied an alkaline extraction then acidified the nuclei which allowed him to see clearly the DNA. He did not know exactly what its function was, but his discovery has inspired many scientists and the na ...
REVIEW SHEET Name - Van Leer Science!
REVIEW SHEET Name - Van Leer Science!

... 26. DNA replication results in two new -?- strands of DNA. ...
Test REVIEW!
Test REVIEW!

... Cytosine (C), thymine (T), adenine (A), and guanine (G) Phosphate, deoxyribose sugar, and nitrogenous bases Nucleotides-building blocks for nucleic acids; held together by hydrogen bonds ...
Transcription Worksheet
Transcription Worksheet

... Use the diagram to answer the questions. 1. Which two mRNA codes correspond to histidine? 2. How many different mRNA codes correspond to arginine? © Pearson Education, Inc., publishing as Pearson Prentice Hall. ...
DNA Replication
DNA Replication

... Chargaff (1940s) – determined that in any species the amount of adenine and thymine were virtually the same, as was the amount of guanine and cytosine. Franklin (1951)– used X-ray crytallography to photograph the DNA molecule; showed that DNA was coiled in a helix. ...
Genetics 1 Notes
Genetics 1 Notes

... Structure of DNA The bases are connected to a complimentary strand by hydrogen bonding between paired bases, adenine (A) with thymine (T) and guanine (G) with cytosine (C) A and T are connected by two hydrogen bonds while G and C are connected by three The hydrogen bonds are very, very, very weak. T ...
Chapter 20: Carboxylic Acids and Nitriles
Chapter 20: Carboxylic Acids and Nitriles

... Copies DNA molecules by unwinding the double helix and copying each strand using enzymes  The new double helices are unwound and copied again  The enzyme is selected to be fast, accurate and heatstable (to survive the unwinding)  Each cycle doubles the amount of material  This is exponential tem ...
RhODIS - Rhino Resource Center
RhODIS - Rhino Resource Center

... • DNA to ensure hunt permit compliance ...
emery Leesburg High School Science Lesson Plan Monday7
emery Leesburg High School Science Lesson Plan Monday7

... guanine, cytosine, thymine, genetic, conservation, synthesis, diversity, traits, helicase, DNA polymerase ...
Schedule
Schedule

... is where a single base changes in the DNA sequence. It can have little or no effect on the amino acid produced, because amino acids have more than one possible codon sequence for them. This means that if there was a point mutation, then the same amino acid could still be coded for. This would then r ...
Tail DNA-Rapid Method - UMass Medical School
Tail DNA-Rapid Method - UMass Medical School

... solutions reserved for genomic use. These include Eppendorf tubes, proteinase K, dH2O, ethanol, and TE. When pipetting genomic DNA samples, only use pipette tips from which the tips have been snipped off (or purchased large-bore tips). This prevents shearing of the DNA, maintaining an average molecu ...
Chemical Basis of Life
Chemical Basis of Life

... DNA is typically a double-stranded helix: A pairs with T, C pairs with G Function: Encoding the Amino Acid sequence of proteins: The sequence of nucleotides in the nucleic acid of a gene determines the sequence of amino acids in the protein that the gene encodes. ...
Wear a chimp on your wrist
Wear a chimp on your wrist

... from it to do the same job. However, more closely related animals do tend to have a more similar DNA sequence for the same gene. (You can see that there are very few differences between the chimp and the human DNA sequence.) ...
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DNA nanotechnology



DNA nanotechnology is the design and manufacture of artificial nucleic acid structures for technological uses. In this field, nucleic acids are used as non-biological engineering materials for nanotechnology rather than as the carriers of genetic information in living cells. Researchers in the field have created static structures such as two- and three-dimensional crystal lattices, nanotubes, polyhedra, and arbitrary shapes, as well as functional devices such as molecular machines and DNA computers. The field is beginning to be used as a tool to solve basic science problems in structural biology and biophysics, including applications in crystallography and spectroscopy for protein structure determination. Potential applications in molecular scale electronics and nanomedicine are also being investigated.The conceptual foundation for DNA nanotechnology was first laid out by Nadrian Seeman in the early 1980s, and the field began to attract widespread interest in the mid-2000s. This use of nucleic acids is enabled by their strict base pairing rules, which cause only portions of strands with complementary base sequences to bind together to form strong, rigid double helix structures. This allows for the rational design of base sequences that will selectively assemble to form complex target structures with precisely controlled nanoscale features. A number of assembly methods are used to make these structures, including tile-based structures that assemble from smaller structures, folding structures using the DNA origami method, and dynamically reconfigurable structures using strand displacement techniques. While the field's name specifically references DNA, the same principles have been used with other types of nucleic acids as well, leading to the occasional use of the alternative name nucleic acid nanotechnology.
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