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Recombinant DNA (DNA Cloning)
Recombinant DNA (DNA Cloning)

... such as a bacterial virus or plasmid into which foreign DNA can be inserted • Recombinant DNA: joining together of two fragments of DNA that are not normally joined together (e.g. joining together of eukaryotic DNA and prokaryotic DNA - usually in a cloning vector) ...
New Molecular Based Methods of Diagnosis
New Molecular Based Methods of Diagnosis

... which binds to the other strand of the DNA molecule, all four nucleotides and a thermostable DNA polymerase. The primers must be unique to the DNA being amplified and they flank the region of the DNA to be amplified. ...
TACCCAAAATCC
TACCCAAAATCC

... The first step in protein synthesis is transcription. In this process, RNA is synthesized using DNA as a template. The enzyme RNA polymerase binds to one strand (the sense strand) of the DNA molecule. While causing the DNA to unwind, the RNA polymerase moves along the sense strand, making an RNA cha ...
DNA Structure
DNA Structure

... • Two polynucleotides (strands) base-paired together GC, AT (complementary base-pairing) • Double helix • Two sugar-phosphate backbones run in opposite 5´ to 3´ directions - antiparallel • One DNA molecule includes many genes ...
Extracting DNA Lab – S
Extracting DNA Lab – S

... DNA is found in every living organism. It is among the largest molecules known today. To obtain DNA from any organism, it must first be released from a cell. Once in solution, scientists use specific techniques to spool the DNA fragments together, as observed by Oswald Avery, who once wrote in his s ...
Life Goes On Molecular Genetics Components of DNA
Life Goes On Molecular Genetics Components of DNA

... works in the opposite  direction  ­ away  from  the replication  fork  •  creates a short  segment  of DNA and  as the replication  bubble  grows  another  short strand can be  made ­ Okazaki  fragments  •  Require RNA primer  be made  by a primase  •  DNA ligase  “ligates”  the sugar­phosphate  bac ...
PROTEIN SYNTHESIS CIRCLE REVIEW
PROTEIN SYNTHESIS CIRCLE REVIEW

... The genetic material that leaves the nucleus is the The actual production of proteins occurs in the The process of turning the mRNA code into proteins is called The production of mRNA in eukaryotes occurs in the The production of mRNA in prokaryotes occurs in the New proteins are synthesized on a A ...
DNA: The stuff of Inheritance
DNA: The stuff of Inheritance

...  The two side chains of DNA are built of  Adenine and Guanine are purines, alternating molecules of the sugar consisting of two carbon-nitrogen rings. deoxyribose and phosphate groups.  Thymine and Cytosine are pyrimidines, They run in opposite directions. made of only one carbon-nitrogen ring.  ...
Ch 16 MolecularBasisofInheritance - APBIO-CON
Ch 16 MolecularBasisofInheritance - APBIO-CON

... It takes E. coli less than an hour to copy each of the 5 million base pairs in its single chromosome and divide to form two identical daughter cells. ...
Molecular Genetics Quiz
Molecular Genetics Quiz

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Lecture #7 Date

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Sample Exam 3 Questions
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... one from each parent. About a decade ago, a child was born in Germany who inherited a point mutation in his myostatin gene from both parents. This particular point mutation results in short, inactive myostatin proteins. At 7 months, the boy already had well-developed calf, thigh, and buttock muscles ...
Investigation of the structure of DNA
Investigation of the structure of DNA

... Results showed that power 40x is more textured and detailed than the other powers. However the power 4x showed more variety of sizes and shapes of substances, strands, bubble and shadings of different colours. (blue and green) ...
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Section E
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... 3. DNA polymerase I: Once the lagging strand primers have been elongated by DNA polymerase III, they are removed and the gaps filled by DNA polymerase I, which has: – 5'3' exonuclease: removes the primers (Fig. 3); – 5'3' polymerase: fills the gaps with DNA by elongating the 3'-end of the adjacent ...
dna condensation and how it relates to phase
dna condensation and how it relates to phase

... High molecular weight DNA is a randomly coiled polymer usually found to be highly expanded in solution due to its low degree of flexibility. It has been shown, however, that DNA is able to undergo a sudden conformational transition into a highly compacted conformation. The collapse transition or con ...
DNA - The Double Helix
DNA - The Double Helix

... controls the production of proteins within the cell. These proteins in turn, form the structural units of cells and control all chemical processes within the cell. Think of proteins as the building blocks for an organism, proteins make up your skin, your hair, parts of individual cells. How you look ...
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...  Elements of complementary nature spontaneously “stick” together.  This “complementary-attraction-principle” seems to pervade many aspects of life (both molecular and higher levels). ...
Genes- PRACTICE PROBLEMS- ANSWERS
Genes- PRACTICE PROBLEMS- ANSWERS

... transcribing it into mRNA, and then into the amino acids or proteins. b. Changes in RNA and protein do not affect DNA because the process of gene expression is not circular and is unidirectional. c. A change in DNA would result in a changed code for protein, so that the codons in mRNA would be alter ...
DNA and RNA
DNA and RNA

... This helped to determine that DNA stores and transmits genetic information. ...
DNA - OCW UI
DNA - OCW UI

... capable of folding back on itself like a hairpin and thus acquiring doublestranded characteristics. ...
DNA Barcoding
DNA Barcoding

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X – Ray Diffraction
X – Ray Diffraction

... • Features of Model 1. Outside strands consist of alternating deoxyribose and phosphate 2. C = G pair to each other with 3 hydrogen bonds 3. T = A pair to each other with 2 hydrogen bonds ...
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DNA replication



DNA replication is the process of producing two identical replicas from one original DNA molecule. This biological process occurs in all living organisms and is the basis for biological inheritance. DNA is made up of two strands and each strand of the original DNA molecule serves as a template for the production of the complementary strand, a process referred to as semiconservative replication. Cellular proofreading and error-checking mechanisms ensure near perfect fidelity for DNA replication.In a cell, DNA replication begins at specific locations, or origins of replication, in the genome. Unwinding of DNA at the origin and synthesis of new strands results in replication forks growing bidirectional from the origin. A number of proteins are associated with the replication fork which helps in terms of the initiation and continuation of DNA synthesis. Most prominently, DNA polymerase synthesizes the new DNA by adding complementary nucleotides to the template strand.DNA replication can also be performed in vitro (artificially, outside a cell). DNA polymerases isolated from cells and artificial DNA primers can be used to initiate DNA synthesis at known sequences in a template DNA molecule. The polymerase chain reaction (PCR), a common laboratory technique, cyclically applies such artificial synthesis to amplify a specific target DNA fragment from a pool of DNA.
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