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Hallucinogens - People Server at UNCW
Hallucinogens - People Server at UNCW

... Are doses used in preclinical research too high? • neurotoxic doses in non-humans (5-20 mg/kg twice or more/day for several days) are generally higher than would be typical of human use. • However, people often take several tablets at a time or throughout a night’s binge and a tablet may contain up ...
Glossary key terms Ch09
Glossary key terms Ch09

... A syndrome in which those who take up regular cannabis use are more likely to be those who exhibit apathy, loss of ambition and difficulty concentrating. Amphetamines A group of synthetic drugs used primarily as a central nervous system stimulant. Common forms are amphetamine itself Benzedrine), dex ...
Central nervous system (CNS) research is highly dependent
Central nervous system (CNS) research is highly dependent

... live animal is subjected to a sequence of tests to determine the behavioral effect of a drug. Currently, behavioral testing on model animals is a very time-consuming, costly, and subjective process requiring a significant amount of behavioral research expertise. The approach to model the phenotypica ...
Motility
Motility

... medicine. Intestinal motility is already impaired in many animals with diarrhea, and these drugs may actually worsen the diarrhea. The anticholinergic drugs also have profound systemic pharmacologic effects. If they are administered in sufficient doses to affect intestinal motility, possible side ef ...
Psychopharmacology
Psychopharmacology

... reward system of the abstinent rat (‘the first one is free’), causing craving and relapse ...
Street Drugs - Centegra Health System
Street Drugs - Centegra Health System

... the mucous membranes. Users state they get the same rush as the IV use. Oral is a less common form than any other route and there tends to be little to no rush. Short term effects of heroin are euphoria, dry mouth, warm skin and shallow respirations. Additional effects can be dry itchy skin, constri ...
Chemical Dependency
Chemical Dependency

...  IV or intranasal route; Crack (dilute) form is smoked  Rapid Effects and Rapidly metabolized:  Intense euphoria  Increased mental alertness  Increased motor and cardiac activity ...
CHEMICAL MESSENGERS
CHEMICAL MESSENGERS

... alertness and arousal; implicated in depression / mood regulation ...
教案- Pharmacologic Management of Parkinsonism
教案- Pharmacologic Management of Parkinsonism

... Several noncatecholamine dopamine receptor agonists have also been developed and may lead 10min to clinical benefit, as discussed in the text that follows. Dopamine receptors of the D1 type are located in the pars compacta of the substantia nigra and presynaptically on striatal axons coming from cor ...
New Trends in Street Drugs Rochester Trends
New Trends in Street Drugs Rochester Trends

... Like Amphetamines, they stimulate the CNS and have ...
About ATODA
About ATODA

... • Naloxone (Narcan ®) is a schedule 4 opioid antagonist used to reverse the effects of opioid overdose. Naloxone is widely used in Australia and internationally by paramedics and emergency room staff in cases of suspected opioid overdose. It has no psychoactive effect, is not a drug of dependence, a ...
Magic mushrooms (L)
Magic mushrooms (L)

... Limited dopamine release ...
drugs and their effects 15
drugs and their effects 15

... 6. Brief description & effects of all the specific drugs we talked about (see back of Drug Practice Quiz 1) 7. Explain how drugs change the brain in 2 ways (neurotransmitters and receptors, leading to tolerance) 8. Drug delivery methods (fastest to slowest) 9. 2 reasons why GHB/Rohypnol is used as d ...
Chapter 15
Chapter 15

... – Slows down body processes ...
CHEMICAL MESSENGERS
CHEMICAL MESSENGERS

... 1. __________ - common and pervasive chemical important in regulation of motor movements, emotional and cognitive processes, and reinforcement - schizophrenia (increased dopamine activity) - Parkinson’s Disease (decreased activity) • Different drugs affect dopamine levels in different ways:  stimul ...
File
File

...  Depression often results as the drug wears off.  Stimulants are highly addictive.  Overdose can result in irregular heart beat, heart attack, stroke, seizures, coma, and death.  Amphetamines, also called “speed.”  Cocaine, including crack cocaine  Derived from the South American coca plant  ...
Neurotransmitters
Neurotransmitters

... A scientist develops a drug that blocks the actions of cocaine by locking into the same receptor sites as cocaine. So long as a person is taking the drug, cocaine will no longer produce a high. Would this drug be an antagonist or an agonist to cocaine? Why? ...
SUBSTANCE ABUSE AND ADDICTION BASIC INFORMATION
SUBSTANCE ABUSE AND ADDICTION BASIC INFORMATION

... • Altered activity levels—either stupor and sleeplike states or frenzies. • Unpleasant or painful symptoms when the abused substance is withdrawn. CAUSES Substances of abuse may produce addiction or dependence. The most common substances of abuse include: • Nicotine. • Alcohol. • Marijuana. • Amphet ...
Rickett Benkiser - American Osteopathic Association
Rickett Benkiser - American Osteopathic Association

... Each synthetic cannabinoid is between 5-200 X more potent than THC What is the plant material? ...
NIDA Commonly Abused Prescription Drug Chart
NIDA Commonly Abused Prescription Drug Chart

... Medications can be effective when they are used properly, but some can be addictive and dangerous when abused. This chart provides a brief look at some prescribed medications that—when used in ways or by people other than prescribed—have the potential for adverse medical consequences, including addi ...
DRUG RECOGNITION AND TRENDS
DRUG RECOGNITION AND TRENDS

... • MDMA is a synthetic, psychoactive drug with both stimulant and hallucinogen properties. • MDMA was synthesized in 1914 • First produced for the black market in 1970s • It was placed on Schedule I by the Drug Enforcement Administration in 1985 • Has been made in UK but, more commonly manufactured i ...
the lowdown painkillers drug facts
the lowdown painkillers drug facts

... Prescription painkillers often contain opioids that are either naturally derived from poppy flowers, or a lab-made, semi-synthetic substitute. These drugs attach to particular sites in the brain called opioid receptors, which carry messages to the brain. When you take prescription painkillers, the m ...
A1987L059000002
A1987L059000002

... clonidine represents a novel class of drugs that appear with a typical cardiovascular pattern, triggered by a specific action upon medullary central nervous system sites. The molecular basis of these actions was attributed to a stimulation of medullary cs-adrenoceptors. Pharmacological evidence indi ...
Anti-depressants
Anti-depressants

... diet is needed. ? Obsolete. Moclobemide.  Only MAOI-A.  ? Role.  ? Special place in anxiety disorder.  300-600mg / day. ...
Problem amphetamine and methamphetamine use
Problem amphetamine and methamphetamine use

... this is that, in the present day, problem amphetamines use across Europe is marked by strong national characteristics, possibly more so than any other of the major illicit drugs. Amphetamine and methamphetamine ...
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Stimulant



Stimulants (also referred to as psychostimulants) are psychoactive drugs that induce temporary improvements in either mental or physical functions or both. Examples of these kinds of effects may include enhanced alertness, wakefulness, and locomotion, among others. Due to their rendering a characteristic ""up"" feeling, stimulants are also occasionally referred to as ""uppers"". Depressants or ""downers"", which decrease mental and/or physical function, are in stark contrast to stimulants and are considered to be their functional opposites. Stimulants are widely used throughout the world as prescription medicines and without prescription both as legal substances and illicit substances of recreational use or abuse.
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