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Slide 1
Slide 1

... The drug metabolite may be: Inactive: metabolism results in termination of drug action e.g. most drugs. Active like the parent drug: e.g. diazepam (sedative and hypnotic). Active and the parent drug is inactive: (prodrug) e.g. methotrexate ...
Injectable Anesthetics - Dr. Roberta Dev Anand
Injectable Anesthetics - Dr. Roberta Dev Anand

...  Not a sedative or analgesic  Must pre-medicate  Alpha-2’s or acepromazine  May cause excitement if not  Increased risk of side effects if not ...
pre-anesthetic agents - Dr. Roberta Dev Anand
pre-anesthetic agents - Dr. Roberta Dev Anand

...  _______________________________: some preanesthetic agents last long enough to be effective postoperatively ...
Effects and Risks Associated with Novel Psychoactive Substances
Effects and Risks Associated with Novel Psychoactive Substances

... the Internet and elsewhere. Such substances are widely taken by young people as “club drugs.” Their consumption must be considered in the differential diagnosis of psychiatric, neurological, cardiovascular, or metabolic disturbances of unclear origin in a young patient. Methods: Selective review of ...
Anesthesia for Geriatric Patients
Anesthesia for Geriatric Patients

... – The hemodynamic effects of RA may reduce blood loss in pelvic and lower extremity operations. – More important, the patient maintains his airway and pulmonary function. ...
THC - Department of Psychology
THC - Department of Psychology

... useful for treating mild to moderate depression. However, recent studies suggest that St. John's Wort is of no benefit in treating major depression of moderate severity. ...
1 Top Pediatric Medications Common Pediatric
1 Top Pediatric Medications Common Pediatric

... Ń Is generally faster than normal adult levels until age 2, then slowly declines until puberty, and finally drops to normal adult levels. Ń This may mean increased dosage or dosing frequency for drugs eliminated by hepatic metabolism. ...
Substance Abuse - Mother Baby University
Substance Abuse - Mother Baby University

...  Sensory organs: increased auditory startle response; abnormal ABR  Cardiac: arrhythmias; hypertension; decreased cardiac output ...
Take Meds Faithfully - Consumer Reports Health
Take Meds Faithfully - Consumer Reports Health

... patients think they know better than I do what’s good for them.” Non-compliance is also substantially due to the fact that many chronic conditions have no or few symptoms. In such cases, taking a pill everyday that may have side effects can actually seem like an irrational thing to do. The two most ...
Benzodiazepine Pharmacology and Central Nervous System
Benzodiazepine Pharmacology and Central Nervous System

... pharmacology and physiology, the mechanisms of action of many BZDs are now largely understood, and BZDs of varying potency and duration of action have been developed and marketed. Although BZDs have many therapeutic roles and BZD-mediated effects are typically well tolerated in the general populatio ...
America`s State of Mind Report
America`s State of Mind Report

... According to Medco’s data, use of antidepressants among children rose significantly at  the beginning of the decade, reaching its peak in 2004 and then falling back down in  2010 to levels similar to what was seen in 2001.  The drop in use of these drugs can be  correlated to the Food and Drug Admin ...
Regional Chapter Presidents` Meeting
Regional Chapter Presidents` Meeting

... Low or no level of primary or secondary pharmacology concern Target expression, activity or exposure not in lung, nerves, muscle When Cmax at steady state are very different then acute dosing Cumulative effects expected based on primary or secondary pharmacology of therapeutic/chemical class Delayed ...
15-pharmacology(dr Amani badawi) -
15-pharmacology(dr Amani badawi) -

... conjunctivitis, vernal keratoconjunctivitis, prevention and suppression of corneal graft rejection, episcleritis, scleritis • Side effects: susceptibility to infections, glaucoma, cataract, ...
Quick Reference for Antidepressants
Quick Reference for Antidepressants

... May lower seizure threshold over 300 mg. Avoid if seizure history, eating disorder, CNS lesions or trauma. May cause anxiety or insomnia, may be to activating ...
ocena dokumentacji chemicznej, farmaceutycznej i biologicznej
ocena dokumentacji chemicznej, farmaceutycznej i biologicznej

... A formal interaction study investigating the potential of drug interaction between nitrendipine and anticonvulsants has not been performed. However, phenytoin, phenobarbitone and carbamazepine are known as potential inducers of the cytochrome P450 3A4 system. Furthermore, concomitant administration ...
what are opioids?
what are opioids?

... opioids are used for pain relief and can bring on feelings of well being. They act as a depressant on the central nervous system which means they slow down functions in the brain and body. Opioids can also cause coma and death in high doses. ...
File - Wk 1-2
File - Wk 1-2

...  In order for a drug to be excreted in the urine, it must by hydrophilic, whereas most drugs on administration is lipophilic (which enables them to cross cell membranes)  Ionized drugs (which are filtered during glomerular filtration in the kidney) undergo little reabsorption and are excreted  Li ...
antidepressant drug overdoses
antidepressant drug overdoses

... groups depending on their effects on the central nervous system (CNS) neurotransmitters dopamine, epinephrine, norepinephrine, and serotonin. Abnormal levels of these neurotransmitters are associated with depression, migraine, bipolar disorder, and anxiety. An antidepressant’s effectiveness and pote ...
CAFFEINE JITTERS
CAFFEINE JITTERS

... of its product contains only about half the caffeine found in a 16-oz cup of premium coffee, such as Starbucks. Caffeine safety has proven hard to measure. Although scientists have established the toxic dose to be somewhere around 10 g, they say that the value can fluctuate depending on how a person ...
ppt - Department of Public Health Pharmacology & Tox.
ppt - Department of Public Health Pharmacology & Tox.

... • The fungal cell wall contains chitin and polysaccharides making it rigid, and acts as a barrier to drug penetration. • The cell membrane contains ergosterol, which influences the efficacy and the risk of drug resistance. • Most antifungal agents are fungistatic with infectionclearance largely depe ...
pharmacokinetics-4
pharmacokinetics-4

... others, depending on their lipid solubility. Small pores, 8 angstroms, permit small molecules such as alcohol and water to pass through. Walls of Capillaries: Pores between the cells are larger than most drug molecules, allowing them to pass freely, without lipid solubility being a factor. Blood/Bra ...
lab#1 pharmacology
lab#1 pharmacology

... Physiograph and thermostatically controlled organ bath. Drugs acting on the isolated tissue: • isolated rabbit intestine has normal myogenic contraction which is under the control of the Autonomic nervous system (ANS). • The effect of drugs that act on the intestine could be a stimulatory i.e. incre ...
Kim Woolf presentation – ppt - Australasian College of Road Safety
Kim Woolf presentation – ppt - Australasian College of Road Safety

... Drug Driving 2016 KW (c) ...
Thiazide and Thiazide
Thiazide and Thiazide

... thiazide-like diuretics were used in most of the early studies which established the benefit of treating hypertension albeit often at doses far in excess of those currently recommended. More recently, lowdose thiazides have often been included as add-on therapy in studies demonstrating outcome benef ...
Vol. 21, No. 4 In the News
Vol. 21, No. 4 In the News

... well known adverse effects of rhabdomyolysis and myopathy associated with statin therapy.(3). Indeed, a number of studies have investigated the effect of statins on CoQ10 (4,5,6,7,8). Most consistently, statins have reduced CoQ10 levels (4,5,6,8). However, several of the studies measured the concent ...
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Stimulant



Stimulants (also referred to as psychostimulants) are psychoactive drugs that induce temporary improvements in either mental or physical functions or both. Examples of these kinds of effects may include enhanced alertness, wakefulness, and locomotion, among others. Due to their rendering a characteristic ""up"" feeling, stimulants are also occasionally referred to as ""uppers"". Depressants or ""downers"", which decrease mental and/or physical function, are in stark contrast to stimulants and are considered to be their functional opposites. Stimulants are widely used throughout the world as prescription medicines and without prescription both as legal substances and illicit substances of recreational use or abuse.
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