Solomons Judgement Dr M Rowlands 24th Jan 2014
... Methadone maintenance results in improved maternal & foetal health & should be offered to opioid dependent pregnant women (B) Less data are available for buprenorphine maintenance but it appears similar benefits are seen for mothers & foetus as for methadone(B) Detoxification should be avoided i ...
... Methadone maintenance results in improved maternal & foetal health & should be offered to opioid dependent pregnant women (B) Less data are available for buprenorphine maintenance but it appears similar benefits are seen for mothers & foetus as for methadone(B) Detoxification should be avoided i ...
Psychotropic drug interactions
... Competition for binding sites may result in an increase in unbound plasma levels of drugs that are highly proteinbound (>90%). Protein-binding interactions may only be significant for drugs with a small volume of distribution or where a temporary increase in plasma levels may result in unacceptable ...
... Competition for binding sites may result in an increase in unbound plasma levels of drugs that are highly proteinbound (>90%). Protein-binding interactions may only be significant for drugs with a small volume of distribution or where a temporary increase in plasma levels may result in unacceptable ...
Phil Rowe Reader in pharmaceutical computing School of
... Creatinine is a chemical produced by muscles and excreted via the kidneys. If renal function is normal, creatinine is cleared quickly and blood levels remain low in renal disease creatinine levels increase. 'Creatinine clearance' therefore used as a marker of renal function. If creatinine clearance ...
... Creatinine is a chemical produced by muscles and excreted via the kidneys. If renal function is normal, creatinine is cleared quickly and blood levels remain low in renal disease creatinine levels increase. 'Creatinine clearance' therefore used as a marker of renal function. If creatinine clearance ...
Toxicology - Madison County EMD
... Origin-Heroin is an opiate drug that is synthesized from morphine, a naturally occurring substance extracted from the seed pod of the Asian opium poppy plant Action-Works on opiate receptor in the brain specifically mu, kappa, and delta receptors in the central nervous system Onset-Intravenous ...
... Origin-Heroin is an opiate drug that is synthesized from morphine, a naturally occurring substance extracted from the seed pod of the Asian opium poppy plant Action-Works on opiate receptor in the brain specifically mu, kappa, and delta receptors in the central nervous system Onset-Intravenous ...
Bromazepam
... Once physical dependence has developed, abrupt termination of treatment will be accompanied by withdrawal symptoms. These may consist of headaches, diarrhoea, muscle pain, extreme anxiety, tension, restlessness, confusion and irritability. In severe cases the following symptoms may occur: derealisat ...
... Once physical dependence has developed, abrupt termination of treatment will be accompanied by withdrawal symptoms. These may consist of headaches, diarrhoea, muscle pain, extreme anxiety, tension, restlessness, confusion and irritability. In severe cases the following symptoms may occur: derealisat ...
WHY ARE WE STILL STUCK AROUND BENZODIAZEPINES? Introduction SMMGP Manchester, October 2013
... • Wide variety in clinical practice • BZ sometimes given as “quick fix” in general practice • Sometimes BZ given rather than opioid ...
... • Wide variety in clinical practice • BZ sometimes given as “quick fix” in general practice • Sometimes BZ given rather than opioid ...
Treatment of Hayfever Vol 3 No 2 (PDF 46Kb)
... during defined parts of the year. Grass is the commonest allergen implicated and the symptoms associated with this condition include sneezing, rhinorrhoea, watery eyes, nasal congestion, itching in the throat, eyes and ears and oedema around the eyes. Hay fever is strictly seasonal as distinct from ...
... during defined parts of the year. Grass is the commonest allergen implicated and the symptoms associated with this condition include sneezing, rhinorrhoea, watery eyes, nasal congestion, itching in the throat, eyes and ears and oedema around the eyes. Hay fever is strictly seasonal as distinct from ...
Center for Development of Human Services
... Research has demonstrated that compared with children in non-substance abusing households, children of substance abusing parents are more likely to experience neglect or physical, sexual, or emotional abuse. A parent’s inability to function in a parental role may be due to a disproportionate amount ...
... Research has demonstrated that compared with children in non-substance abusing households, children of substance abusing parents are more likely to experience neglect or physical, sexual, or emotional abuse. A parent’s inability to function in a parental role may be due to a disproportionate amount ...
Adrenergic drugs
... Dry, nonproductive cough, which reverses when therapy is stopped Angioedema: rare but potentially fatal ...
... Dry, nonproductive cough, which reverses when therapy is stopped Angioedema: rare but potentially fatal ...
and drug
... Theoretically, the amount of randomly selected drugs having bioavailability in the CNS is less than 2% of small molecules and practically 0% of large molecules. These numbers are also reflected by the drugs currently available for CNS diseases. Of over 7,000 potential drugs in the comprehensive medi ...
... Theoretically, the amount of randomly selected drugs having bioavailability in the CNS is less than 2% of small molecules and practically 0% of large molecules. These numbers are also reflected by the drugs currently available for CNS diseases. Of over 7,000 potential drugs in the comprehensive medi ...
used
... thus causes hyperpolarization of the cell. b. When BDZs bind to their receptor on the GABAA complex, they enhance the effect of GABA by increasing the number of times the chloride channel opens. However, in the absence of GABA, BDZs have no effect. Barbiturates also increase the affinity of the GAB ...
... thus causes hyperpolarization of the cell. b. When BDZs bind to their receptor on the GABAA complex, they enhance the effect of GABA by increasing the number of times the chloride channel opens. However, in the absence of GABA, BDZs have no effect. Barbiturates also increase the affinity of the GAB ...
![Chapter 5 Over the counter drugs[1].](http://s1.studyres.com/store/data/010743665_1-d2aa6b8894f079cb577688845957c18b-300x300.png)
Chapter 5 Over the counter drugs[1].
... 1. Liquorice or plant extract: They are irritants of the gastric mucosa and they stimulate the afferent fibers of the vagus nerve to the medulla. This results in increased parasympathetic stimulation of the efferent fiber of the vagus nerve back to the stomach. Vagal stimulation to the lungs increa ...
... 1. Liquorice or plant extract: They are irritants of the gastric mucosa and they stimulate the afferent fibers of the vagus nerve to the medulla. This results in increased parasympathetic stimulation of the efferent fiber of the vagus nerve back to the stomach. Vagal stimulation to the lungs increa ...
The role of polypharmacy in children with developmental
... Literature says polypharmacy leads to: Increase in drug interactions Decrease in adherence Adverse outcomes for patient “the use of therapeutic agents represents a trade off between benefits of symptoms relief or disease modification that increase quality of life and the risk of short and long term ...
... Literature says polypharmacy leads to: Increase in drug interactions Decrease in adherence Adverse outcomes for patient “the use of therapeutic agents represents a trade off between benefits of symptoms relief or disease modification that increase quality of life and the risk of short and long term ...
Drugs and Toxicology
... Anabolic steroids promote cell growth resulting in growth of muscle tissue and sometimes bone size and strength ...
... Anabolic steroids promote cell growth resulting in growth of muscle tissue and sometimes bone size and strength ...
drugs affecting breast milk and lactation
... • Breast feeding is very important because mother’s milk is the best nutritious , most compatible and healthiest form of milk for babies. • It also Provides the baby with immunoglobulins (IgA, IgM) that are essential for protection against gastroenteritis. ...
... • Breast feeding is very important because mother’s milk is the best nutritious , most compatible and healthiest form of milk for babies. • It also Provides the baby with immunoglobulins (IgA, IgM) that are essential for protection against gastroenteritis. ...
Routes of Administration
... Knowing half-life is important for understanding time course of drug and how often to administer it. A drug’s effects may be longer and more intense if liver and/or kidney are not functioning up to par. ...
... Knowing half-life is important for understanding time course of drug and how often to administer it. A drug’s effects may be longer and more intense if liver and/or kidney are not functioning up to par. ...
Basic Principles of Pharmacology
... man unless there is a high suspicion that the drug could be carcinogenic e.g. suspicion of mutagenicity; highly reactive groups on drug; histopathological abnormalities… Required if the use of drug in man for more than one year or +ve mutagenic test ...
... man unless there is a high suspicion that the drug could be carcinogenic e.g. suspicion of mutagenicity; highly reactive groups on drug; histopathological abnormalities… Required if the use of drug in man for more than one year or +ve mutagenic test ...
Product Knowledge
... Yohimbine is just right for the thermogenetic concoction in LIPO-6 to help induce lipolysis (fat burning) without the side effects from other fat burners (i.e. increased heart rate, increased blood pressure, anxiety)(14, 15) In particular, Yohimbine induces fat breakdown where fat stores prevail as ...
... Yohimbine is just right for the thermogenetic concoction in LIPO-6 to help induce lipolysis (fat burning) without the side effects from other fat burners (i.e. increased heart rate, increased blood pressure, anxiety)(14, 15) In particular, Yohimbine induces fat breakdown where fat stores prevail as ...
Questions and answers on NPS
... Synthetic cathinones – These are analogues/derivatives of the internationally controlled substance cathinone, one of the active components of the khat plant. They generally have stimulant effects and include frequently reported NPS such as mephedrone and MDPV. Ketamine - A human and veterinary anest ...
... Synthetic cathinones – These are analogues/derivatives of the internationally controlled substance cathinone, one of the active components of the khat plant. They generally have stimulant effects and include frequently reported NPS such as mephedrone and MDPV. Ketamine - A human and veterinary anest ...
Document
... allow the natural molecule (cocaine dopamine; Prozac etc - serotonin) to remain longer at the site of action • May have beneficial or detrimental effects • May also act as an antidote ...
... allow the natural molecule (cocaine dopamine; Prozac etc - serotonin) to remain longer at the site of action • May have beneficial or detrimental effects • May also act as an antidote ...
Stimulant
Stimulants (also referred to as psychostimulants) are psychoactive drugs that induce temporary improvements in either mental or physical functions or both. Examples of these kinds of effects may include enhanced alertness, wakefulness, and locomotion, among others. Due to their rendering a characteristic ""up"" feeling, stimulants are also occasionally referred to as ""uppers"". Depressants or ""downers"", which decrease mental and/or physical function, are in stark contrast to stimulants and are considered to be their functional opposites. Stimulants are widely used throughout the world as prescription medicines and without prescription both as legal substances and illicit substances of recreational use or abuse.