Nicotine Self-Administration in Animals: A Reevaluation
... recent report of the British Royal College of Physicians (Tobacco Advisory Group of The Royal College of Physicians, 2000), ‘‘nicotine dependence is heavily entrenched in society. It is obviously desirable to reduce both nicotine dependence and the terrible harm caused by nicotine delivery through t ...
... recent report of the British Royal College of Physicians (Tobacco Advisory Group of The Royal College of Physicians, 2000), ‘‘nicotine dependence is heavily entrenched in society. It is obviously desirable to reduce both nicotine dependence and the terrible harm caused by nicotine delivery through t ...
Effects of grapefruit juice on the pharmacokinetics of selected
... About ten years ago, grapefruit juice was observed to increase the plasma concentrations and effects of felodipine. Since then, grapefruit juice has been found to interact with more than 20 different drugs. However, many factors affecting the susceptibility of drugs to interaction with grapefruit ju ...
... About ten years ago, grapefruit juice was observed to increase the plasma concentrations and effects of felodipine. Since then, grapefruit juice has been found to interact with more than 20 different drugs. However, many factors affecting the susceptibility of drugs to interaction with grapefruit ju ...
Is ecstasy MDMA? - Department of Psychology
... In a review of Italian ecstasy/MDMA research, Schifano (2000) noted: “As for the content of ecstasy tablets, sources from local forensic toxicological laboratories, which have examined at least 20,000 ecstasy tablets in the last 5 years, suggest that about 85–90% of ecstasy tablets seized in the nor ...
... In a review of Italian ecstasy/MDMA research, Schifano (2000) noted: “As for the content of ecstasy tablets, sources from local forensic toxicological laboratories, which have examined at least 20,000 ecstasy tablets in the last 5 years, suggest that about 85–90% of ecstasy tablets seized in the nor ...
What factors need to be considered when prescribing for lactose
... temporary or permanent in nature (2). The two most common types are: 1. Primary lactose intolerance, which usually develops between the ages of 2 and 20 years. Affected individuals begin to produce less lactase after age 2 years but symptoms may not present until years later (2). 2. Secondary lactos ...
... temporary or permanent in nature (2). The two most common types are: 1. Primary lactose intolerance, which usually develops between the ages of 2 and 20 years. Affected individuals begin to produce less lactase after age 2 years but symptoms may not present until years later (2). 2. Secondary lactos ...
投影片 1 - Hong Kong Society for Nursing Education Limited
... Keep the patch attached at all times except sleeping hours Remove the patch before you go to bed Apply a new patch in the morning ...
... Keep the patch attached at all times except sleeping hours Remove the patch before you go to bed Apply a new patch in the morning ...
List of Substances of the Competent Federal Government and
... (Not NFS), the Novel Food Catalogue of the European Commission9 was taken into account. However, it should be noted that this catalogue does not have any entries for a large number of substances from the List of Substances in the category “plants and plant parts”. Any other available information reg ...
... (Not NFS), the Novel Food Catalogue of the European Commission9 was taken into account. However, it should be noted that this catalogue does not have any entries for a large number of substances from the List of Substances in the category “plants and plant parts”. Any other available information reg ...
The role of benzoyl peroxide in the management of acne vulgaris
... cne vulgaris is an extremely common and distressing condition that affects over 90 per cent of adolescents between the age of 16 and 18 years.1 Of these, approximately 15 per cent require medical intervention.2 Furthermore, research has shown that acne has a negative impact on patients’ quality of l ...
... cne vulgaris is an extremely common and distressing condition that affects over 90 per cent of adolescents between the age of 16 and 18 years.1 Of these, approximately 15 per cent require medical intervention.2 Furthermore, research has shown that acne has a negative impact on patients’ quality of l ...
Blind copy - Open Journal Systems
... forms were observed as noticed to the majority drugs (15) and efavirenz showed crystals in columnar shape. According to Biopharmaceutical Classification System (BCS), class II drugs as efavirenz are those with low solubility and high permeability and the correlation between in vivo results and disso ...
... forms were observed as noticed to the majority drugs (15) and efavirenz showed crystals in columnar shape. According to Biopharmaceutical Classification System (BCS), class II drugs as efavirenz are those with low solubility and high permeability and the correlation between in vivo results and disso ...
Hydrocodone Polistirex and Chlorpheniramine Polistirex Extended
... depression which may result from overdosage or unusual sensitivity to narcotics including hydrocodone. Therefore, an appropriate dose of naloxone hydrochloride should be administered, preferably by the intravenous route, simultaneously with efforts at respiratory resuscitation. Since the duration of ...
... depression which may result from overdosage or unusual sensitivity to narcotics including hydrocodone. Therefore, an appropriate dose of naloxone hydrochloride should be administered, preferably by the intravenous route, simultaneously with efforts at respiratory resuscitation. Since the duration of ...
Allergan to Acquire Naurex - McCormick School of Engineering
... Both drugs target the brain’s N-methyl-D-aspartate receptors, which are involved in learning and memory. These receptors interact with the neurotransmitter glutamate, the levels of which seem to be out of balance in depression. According to Allergan, both therapies have been well-tolerated in studi ...
... Both drugs target the brain’s N-methyl-D-aspartate receptors, which are involved in learning and memory. These receptors interact with the neurotransmitter glutamate, the levels of which seem to be out of balance in depression. According to Allergan, both therapies have been well-tolerated in studi ...
NUX VOMICA
... decided tonic qualities not present in either when exhibited alone, In other words, they fortify each other. This fact should not be lost to mind when the tonic quality of either substance is desirecl, especially when either fails separately to accomplish the desired effect. This is somewhat in acco ...
... decided tonic qualities not present in either when exhibited alone, In other words, they fortify each other. This fact should not be lost to mind when the tonic quality of either substance is desirecl, especially when either fails separately to accomplish the desired effect. This is somewhat in acco ...
Methamphetamine - Department of Electrical Engineering
... naloxone, which blocks opiate receptors and is therefore used in treating opiate dependence, for use with methamphetamine problems.[69] However, experiments with some monoamine reuptake inhibitors such as indatraline have been successful in blocking the action of methamphetamine.[70] There are studi ...
... naloxone, which blocks opiate receptors and is therefore used in treating opiate dependence, for use with methamphetamine problems.[69] However, experiments with some monoamine reuptake inhibitors such as indatraline have been successful in blocking the action of methamphetamine.[70] There are studi ...
EPAR - Assessment Report - Variation - EMA
... No ERA was initially submitted in this application. The Committee requested an ERA in the first RSI arguing that the extension of the indication might lead to an increase in use, and therefore environmental exposure of the product. In line with the guideline in environmental risk assessment EMEA/CHM ...
... No ERA was initially submitted in this application. The Committee requested an ERA in the first RSI arguing that the extension of the indication might lead to an increase in use, and therefore environmental exposure of the product. In line with the guideline in environmental risk assessment EMEA/CHM ...
Dronabinol and Marijuana in HIV
... marijuana proponents and patients with HIV include countering the nausea, anorexia, stomach upset, and anxiety associated with the disease and with antiretroviral therapy. The benefits of smoked marijuana are that its effects peak rapidly (,20 minutes), allowing for dose titration and immediate symp ...
... marijuana proponents and patients with HIV include countering the nausea, anorexia, stomach upset, and anxiety associated with the disease and with antiretroviral therapy. The benefits of smoked marijuana are that its effects peak rapidly (,20 minutes), allowing for dose titration and immediate symp ...
Salvia Divinorum
... medical studies undertaken to examine the drug's physiological effects have focused only on short-term effects. However, information provided by abusers indicates that the negative longterm effects of Salvia Divinorum may be similar to those produced by other hallucinogens such as LSD (lysergic acid ...
... medical studies undertaken to examine the drug's physiological effects have focused only on short-term effects. However, information provided by abusers indicates that the negative longterm effects of Salvia Divinorum may be similar to those produced by other hallucinogens such as LSD (lysergic acid ...
Chronic tolerance to recreational MDMA
... such as caffeine, paracetamol, ephedrine, ketamine, or placebo (Schifano et al., 1998; King, 2000; Spruit, 2001; see also Table 2 in Parrott, 2004a). The third phase was from the late, 1990s to the present, when the proportion of Ecstasy tablets containing MDMA has increased to values around 80–100% ...
... such as caffeine, paracetamol, ephedrine, ketamine, or placebo (Schifano et al., 1998; King, 2000; Spruit, 2001; see also Table 2 in Parrott, 2004a). The third phase was from the late, 1990s to the present, when the proportion of Ecstasy tablets containing MDMA has increased to values around 80–100% ...
Paediatric formulations of L-arginine for the use in urea cycle disorders
... This work focuses on L-arginine as a treatment for urea cycle disorders (UCDs). It is a genetic disorder caused by a deficiency of one of the enzymes in the urea cycle which is responsible for removing ammonia from the blood stream. The urea cycle involves a series of biochemical steps in which nit ...
... This work focuses on L-arginine as a treatment for urea cycle disorders (UCDs). It is a genetic disorder caused by a deficiency of one of the enzymes in the urea cycle which is responsible for removing ammonia from the blood stream. The urea cycle involves a series of biochemical steps in which nit ...
PDF - Pharmacological Reviews
... A. An approach of merging the mass-action law with mathematical induction and deduction . . 1. The power of mathematical induction and deduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2. Nature’s law . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ...
... A. An approach of merging the mass-action law with mathematical induction and deduction . . 1. The power of mathematical induction and deduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2. Nature’s law . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ...
SCIENTIFIC DISCUSSION
... receiving antiepileptic drug (AED) treatment. The prevalence of active epilepsy, 5-10/1000, is one of the highest among serious neurological disorders with more than 50 million people affected worldwide. Two peaks of incidence are observed, in early childhood and among elderly people. Some patients ...
... receiving antiepileptic drug (AED) treatment. The prevalence of active epilepsy, 5-10/1000, is one of the highest among serious neurological disorders with more than 50 million people affected worldwide. Two peaks of incidence are observed, in early childhood and among elderly people. Some patients ...
Experimental extinction in Pavlovian conditioning
... paradigm for this purpose has been used recently by Blundell, Hall, and Killcross (2001). These investigators assessed the effects of basolateral amygdala lesions in rats on Pavlovianto-instrumental transfer. They observed that the normal tendency of CSs to exert selective control over instrumental ...
... paradigm for this purpose has been used recently by Blundell, Hall, and Killcross (2001). These investigators assessed the effects of basolateral amygdala lesions in rats on Pavlovianto-instrumental transfer. They observed that the normal tendency of CSs to exert selective control over instrumental ...
Chapter 1 Key Terms
... administration category. A drug that binds to a receptor and stimulates the 26. Response limited to one place or part. receptor's function. 27. The ability (of a medication form) to be dissolved. A mixture of water and oil bound together with an 28. The ability of drugs to attach to receptor sites o ...
... administration category. A drug that binds to a receptor and stimulates the 26. Response limited to one place or part. receptor's function. 27. The ability (of a medication form) to be dissolved. A mixture of water and oil bound together with an 28. The ability of drugs to attach to receptor sites o ...
Review articles Treatment of Myoclonus
... myoclonus and identify the underlying disease process. Metabolic derangements or other underlying conditions, if found, need to be treated. Offending drugs causing myoclonus should be removed. Drugs inducing myoclonus include anticonvulsants, levodopa, lithium, monoamine oxidase inhibitors and bismu ...
... myoclonus and identify the underlying disease process. Metabolic derangements or other underlying conditions, if found, need to be treated. Offending drugs causing myoclonus should be removed. Drugs inducing myoclonus include anticonvulsants, levodopa, lithium, monoamine oxidase inhibitors and bismu ...
the PDF
... Abstract. Cognitive enhancers (nootropics) are drugs to treat cognition deficits in patients suffering from Alzheimer’s disease, schizophrenia, stroke, attention deficit hyperactivity disorder, or aging. Cognition refers to a capacity for information processing, applying knowledge, and changing pref ...
... Abstract. Cognitive enhancers (nootropics) are drugs to treat cognition deficits in patients suffering from Alzheimer’s disease, schizophrenia, stroke, attention deficit hyperactivity disorder, or aging. Cognition refers to a capacity for information processing, applying knowledge, and changing pref ...
effect of cytochrome p450 2d6 and 3a enzyme inhibition on
... lesser degree, CYP2D6 are responsible for the oxidative metabolism of oxycodone (Lalovic et al. 2004). Due to its CYP-mediated metabolism, oxycodone might be prone to drug-drug interactions. Since strong opioids like oxycodone have potential to cause dangerous adverse effect, e.g. respiratory depres ...
... lesser degree, CYP2D6 are responsible for the oxidative metabolism of oxycodone (Lalovic et al. 2004). Due to its CYP-mediated metabolism, oxycodone might be prone to drug-drug interactions. Since strong opioids like oxycodone have potential to cause dangerous adverse effect, e.g. respiratory depres ...
Polysubstance dependence
A person with polysubstance dependence is psychologically addicted to being in an intoxicated state without a preference for one particular substance. Although any combination of three drugs can be used, studies have shown that alcohol is commonly used with another substance. This is supported by one study on polysubstance use that separated participants who used multiple substances into groups based on their preferred drug. The three substances were cocaine, alcohol, and heroin, which implies that those three are very popular. Other studies have found that opiates, cannabis, amphetamines, hallucinogens, inhalants and benzodiazepines are often used in combination as well. The results of a long-term or longitudinal study on substance use led the researchers to observe that excessively using or relying on one drug increased the probability of excessively using or relying on another drug.