Product Monograph Template - Standard
... Candida albicans infection: Evidence of localized infections of the nose with Candida albicans was seen on nasal exams in 7 of 2,745 patients treated with AVAMYS® during clinical trials and was reported as an adverse event in 3 patients. When such an infection develops, it may require treatment with ...
... Candida albicans infection: Evidence of localized infections of the nose with Candida albicans was seen on nasal exams in 7 of 2,745 patients treated with AVAMYS® during clinical trials and was reported as an adverse event in 3 patients. When such an infection develops, it may require treatment with ...
Opioids - Waterloo Region Integrated Drugs Strategy
... Why fentanyls?: Fentanyl is a potent opioid, used in anesthesia, for pain, chronic pain, pain in end of life care Typically administered as a patch placed on the skin Fentanyl is produced by pharmaceutical manufacturers Small chemical changes to fentanyl can result in drugs with very similar actions ...
... Why fentanyls?: Fentanyl is a potent opioid, used in anesthesia, for pain, chronic pain, pain in end of life care Typically administered as a patch placed on the skin Fentanyl is produced by pharmaceutical manufacturers Small chemical changes to fentanyl can result in drugs with very similar actions ...
Adverse Effects of Antiepileptic Drugs
... Studies vary widely in the use of COSTART terms and how the complaints are obtained. The use of COSTART is not universal, and a list of AED adverse effects may include terms taken from other sources, such as the World Health Organization’s Adverse Reaction Terminology (WHO-ART), International Classi ...
... Studies vary widely in the use of COSTART terms and how the complaints are obtained. The use of COSTART is not universal, and a list of AED adverse effects may include terms taken from other sources, such as the World Health Organization’s Adverse Reaction Terminology (WHO-ART), International Classi ...
HIGHLIGHTS OF PRESCRIBING INFORMATION --------------------------WARNINGS AND PRECAUTIONS---------------------------
... respectively, for patients receiving 30 mg, 50 mg, and 70 mg of Vyvanse, compared to a 2.0 pound weight gain for patients receiving placebo. Careful follow-up of weight and height in children ages 7 to 10 years who were randomized to either methylphenidate or non-medication treatment groups over 14 ...
... respectively, for patients receiving 30 mg, 50 mg, and 70 mg of Vyvanse, compared to a 2.0 pound weight gain for patients receiving placebo. Careful follow-up of weight and height in children ages 7 to 10 years who were randomized to either methylphenidate or non-medication treatment groups over 14 ...
Methadone Maintenance A Practical Guide to Pharmacotherapy
... Risk Factors for Methadone Toxicity • Use of other central nervous system (CNS) depressants • Lack of tolerance • Respiratory illness • Age • Liver disease • Use of medications which affect methadone metabolism ...
... Risk Factors for Methadone Toxicity • Use of other central nervous system (CNS) depressants • Lack of tolerance • Respiratory illness • Age • Liver disease • Use of medications which affect methadone metabolism ...
8 th International Congress on Drug Therapy in HIV
... of resistance to APL or a change in tropism readout. Resistance to 3TC may have been a component of virologic failure for subjects receiving an APL-containing regimen. (Data not presented here [Kitrinos, etal].) The mechanisms for APL-induced hepatotoxicity are unclear at this time but did not app ...
... of resistance to APL or a change in tropism readout. Resistance to 3TC may have been a component of virologic failure for subjects receiving an APL-containing regimen. (Data not presented here [Kitrinos, etal].) The mechanisms for APL-induced hepatotoxicity are unclear at this time but did not app ...
EFNS guidelines on management of narcolepsy
... Management of narcolepsy with or without cataplexy relies on several classes of drugs, namely stimulants for excessive daytime sleepiness and irresistible episodes of sleep, antidepressants for cataplexy and hypnosedative drugs for disturbed nocturnal sleep. In addition, behavioral measures can be o ...
... Management of narcolepsy with or without cataplexy relies on several classes of drugs, namely stimulants for excessive daytime sleepiness and irresistible episodes of sleep, antidepressants for cataplexy and hypnosedative drugs for disturbed nocturnal sleep. In addition, behavioral measures can be o ...
- International Journal of Advanced Biological and
... Methenamine salts are therapeutic agents and have bactericidal effect. Most gram-positive and gramnegative pathogens are susceptible (Sweetman et al. 2009; Ahrens and Martin 2013; Al-Badr and AlShaikh 2013; Hickling and Nitti 2013). In many countries such as, United States, Austria, Polish, Canada, ...
... Methenamine salts are therapeutic agents and have bactericidal effect. Most gram-positive and gramnegative pathogens are susceptible (Sweetman et al. 2009; Ahrens and Martin 2013; Al-Badr and AlShaikh 2013; Hickling and Nitti 2013). In many countries such as, United States, Austria, Polish, Canada, ...
Clinical Pharmacology of Opioids for Pain - Weill
... brain stem, where GABA acts to inhibit a pain-inhibitory neuron). This disinhibitory action of the opioid has the net effect of exciting a descending inhibitory circuit. The opioid receptors are part of an endogenous opioid system that includes a large number of endogenous opioid peptide ligands. Ba ...
... brain stem, where GABA acts to inhibit a pain-inhibitory neuron). This disinhibitory action of the opioid has the net effect of exciting a descending inhibitory circuit. The opioid receptors are part of an endogenous opioid system that includes a large number of endogenous opioid peptide ligands. Ba ...
Treatment Emergent Violence to Self and Others
... and mania have been reported in adult and pediatric patients being treated with antidepressants for major depressive disorder as well as for other indications, both psychiatric and non-psychiatric." Although FDA has not concluded that these symptoms are a precursor to either worsening of depression ...
... and mania have been reported in adult and pediatric patients being treated with antidepressants for major depressive disorder as well as for other indications, both psychiatric and non-psychiatric." Although FDA has not concluded that these symptoms are a precursor to either worsening of depression ...
KLONOPIN® TABLETS (clonazepam)
... 30 to 40 hours. Clonazepam pharmacokinetics are dose-independent throughout the dosing range. There is no evidence that clonazepam induces its own metabolism or that of other drugs in humans. Pharmacokinetics in Demographic Subpopulations and in Disease States: Controlled studies examining the influ ...
... 30 to 40 hours. Clonazepam pharmacokinetics are dose-independent throughout the dosing range. There is no evidence that clonazepam induces its own metabolism or that of other drugs in humans. Pharmacokinetics in Demographic Subpopulations and in Disease States: Controlled studies examining the influ ...
• Increase in Blood Pressure: Monitor blood pressure and... at appropriate intervals. Use with caution in patients for
... heart rate (about 3-6 bpm), and individuals may have larger increases. While the mean changes alone would not be expected to have short-term consequences, all patients should be monitored for larger changes in heart rate and blood pressure. Caution is indicated in treating patients whose underlying ...
... heart rate (about 3-6 bpm), and individuals may have larger increases. While the mean changes alone would not be expected to have short-term consequences, all patients should be monitored for larger changes in heart rate and blood pressure. Caution is indicated in treating patients whose underlying ...
OSAFLEX 1178 mg powder for oral solution, sachet ENG
... symptoms (especially pain relief) may not be experienced until after several weeks of treatment and in some cases even longer. If no relief of symptoms is experienced after 2-3 months, continued treatment with glucosamine should be re-evaluated. Osaflex should be taken at meals. Additional informati ...
... symptoms (especially pain relief) may not be experienced until after several weeks of treatment and in some cases even longer. If no relief of symptoms is experienced after 2-3 months, continued treatment with glucosamine should be re-evaluated. Osaflex should be taken at meals. Additional informati ...
L. Araliaceae folium hederae helicis
... Standard extract with 0,2-1 mg totalhypericin daily, up to 5 mg, in 2 doses or more. Effect after 2-3 weeks in depressive states. Initially 0,2 mg totalhypericin and increased dose up to max and then decreased dose down to 0,2 mg again as support. dose. In infections 5 mg totalhypericin. Not more th ...
... Standard extract with 0,2-1 mg totalhypericin daily, up to 5 mg, in 2 doses or more. Effect after 2-3 weeks in depressive states. Initially 0,2 mg totalhypericin and increased dose up to max and then decreased dose down to 0,2 mg again as support. dose. In infections 5 mg totalhypericin. Not more th ...
Synergistic Interaction between Fentanyl and
... the advantage of reducing the dose that would be necessary if either drug were used alone, thus potentially decreasing the incidence and severity of associated side effects such as hypotension and motor block.1 However, the nature of the pharmacologic interaction between opioids and local anesthetic ...
... the advantage of reducing the dose that would be necessary if either drug were used alone, thus potentially decreasing the incidence and severity of associated side effects such as hypotension and motor block.1 However, the nature of the pharmacologic interaction between opioids and local anesthetic ...
ACMD Advisory Council on the Misuse of Drugs ACMD consideration of tramadol
... 4. Dependence liability and misuse 4.1. One view is that „tramadol has pharmacodynamic and pharmacokinetic properties that are highly unlikely to lead to dependence‟ (Dayer, et al., 1997) and in another paper it is stated that „while abuse of tramadol may occur, several large studies have demonstrat ...
... 4. Dependence liability and misuse 4.1. One view is that „tramadol has pharmacodynamic and pharmacokinetic properties that are highly unlikely to lead to dependence‟ (Dayer, et al., 1997) and in another paper it is stated that „while abuse of tramadol may occur, several large studies have demonstrat ...
A Mechanistic Approach to Understanding the Factors Affecting
... Solubility is calculated on the basis of the largest strength manufactured. It is defined as the minimum solubility of drug across a pH range of 1 to 8 and at a temperature of 37 ± 0.5°C. High-solubility drugs are those with a ratio of dose to solubility volume that is less than or equal to 250 ml. ...
... Solubility is calculated on the basis of the largest strength manufactured. It is defined as the minimum solubility of drug across a pH range of 1 to 8 and at a temperature of 37 ± 0.5°C. High-solubility drugs are those with a ratio of dose to solubility volume that is less than or equal to 250 ml. ...
CANNABIS-INDUCED IMPAIRMENT OF LEARNING AND MEMORY
... 2008). The precise nature of memory deficits in cannabis users and their neural substrates still require further research (Solowij and Battisti, 2008). In the treatment of memory disorders whether occurring as a part of normal aging or due to a pathological process e.g., Alzheimer's disease, drugs s ...
... 2008). The precise nature of memory deficits in cannabis users and their neural substrates still require further research (Solowij and Battisti, 2008). In the treatment of memory disorders whether occurring as a part of normal aging or due to a pathological process e.g., Alzheimer's disease, drugs s ...
A study with cumulative doses of formoterol and salbutamol in
... drug. The difference in effect between the dose levels (0-1, 1- 2, 2-3, 3 to final administration of 1 mg salbutamol) of each drug was tested by Wilcoxon's signed rank test. For comparison between the two treatments at each dose level, absolute values were applied to pulse rate, blood pressure and t ...
... drug. The difference in effect between the dose levels (0-1, 1- 2, 2-3, 3 to final administration of 1 mg salbutamol) of each drug was tested by Wilcoxon's signed rank test. For comparison between the two treatments at each dose level, absolute values were applied to pulse rate, blood pressure and t ...
Erasmus Partner Universities of Ankara University Faculty of
... To dial abroad from Turkey, dial the international code 00 followed by the country code, and then the number including the local area code, but removing the first 0. For example, a London number with an area code of 0207 would be dialed from Turkey as 00 44 207 followed by the number. To dial Turkey ...
... To dial abroad from Turkey, dial the international code 00 followed by the country code, and then the number including the local area code, but removing the first 0. For example, a London number with an area code of 0207 would be dialed from Turkey as 00 44 207 followed by the number. To dial Turkey ...
Update on treatment of hereditary angioedema Review article
... Type-3 HAE has similar clinical manifestations to the first two types, but differs in that there are no abnormalities in C1-INH level or function.5 A mutation in coagulation factor XII protease (Hageman factor) is suspected to occur in some cases of Type-3 HAE, but causation has not been documented. ...
... Type-3 HAE has similar clinical manifestations to the first two types, but differs in that there are no abnormalities in C1-INH level or function.5 A mutation in coagulation factor XII protease (Hageman factor) is suspected to occur in some cases of Type-3 HAE, but causation has not been documented. ...
safety and pharmacokinetics of a preservative-free
... in 1% to 3% of patients.28 When these two excipients were removed in a newer oral formulation of etoposide, hypersensitivities were not observed, even in patients with previous reaction to the intravenous formulation.30 The neurology and anesthesia communities were wary of preservatives and excipien ...
... in 1% to 3% of patients.28 When these two excipients were removed in a newer oral formulation of etoposide, hypersensitivities were not observed, even in patients with previous reaction to the intravenous formulation.30 The neurology and anesthesia communities were wary of preservatives and excipien ...
Tetracyclines: History and Current Formulation Review
... Minocycline increased in use for the treatment of acne after studies showed that its longer half life (15-25 hours), lower risk for resistance, fewer GI side effects, and less influence of dairy intake on its effect make it a more optimal choice for the battle against P. acnes.3,14 However, the use ...
... Minocycline increased in use for the treatment of acne after studies showed that its longer half life (15-25 hours), lower risk for resistance, fewer GI side effects, and less influence of dairy intake on its effect make it a more optimal choice for the battle against P. acnes.3,14 However, the use ...
Quantification of Pharmacodynamic Interactions between
... and an analgesic (opiate) drug are titrated to achieve adequate CNS depression. A muscle relaxant can be used to facilitate surgical procedures. This anesthetic combination is termed “balanced anesthesia” (Hug, 1990; Lemmens, 1995). Drug combinations may lead to a reduction of the dose requirements ...
... and an analgesic (opiate) drug are titrated to achieve adequate CNS depression. A muscle relaxant can be used to facilitate surgical procedures. This anesthetic combination is termed “balanced anesthesia” (Hug, 1990; Lemmens, 1995). Drug combinations may lead to a reduction of the dose requirements ...
Polysubstance dependence
A person with polysubstance dependence is psychologically addicted to being in an intoxicated state without a preference for one particular substance. Although any combination of three drugs can be used, studies have shown that alcohol is commonly used with another substance. This is supported by one study on polysubstance use that separated participants who used multiple substances into groups based on their preferred drug. The three substances were cocaine, alcohol, and heroin, which implies that those three are very popular. Other studies have found that opiates, cannabis, amphetamines, hallucinogens, inhalants and benzodiazepines are often used in combination as well. The results of a long-term or longitudinal study on substance use led the researchers to observe that excessively using or relying on one drug increased the probability of excessively using or relying on another drug.