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The Psychological and Physical Side Effects of Pain Medications
The Psychological and Physical Side Effects of Pain Medications

... produce multiple symptoms, which may include “loss of libido, infertility, fatigue, depression, anxiety, loss of muscle strength and mass, alteration of gender role, osteoporosis, and compression fractures and, in men, impotence, and, in females, menstrual irregularities, galactorrhea and infertilit ...
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Salvia Divinorum: Establish Restrictions But Don`t Criminalize It
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... majority of those who had tried it said they would not do so again.xxi Importantly, the survey found, “Prevalence rates plummet when observing lifetime use (6.7%), to use within the last year (3.0%), and to use within the last month (0.5%)…this suggests Salvia has a low continuance rate.”xxii In fac ...
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... non-tuberculous mycobacterial diseases and TB [22–29]. Due to the lack of available antibiotics to treat such difficult cases, linezolid is already used off-label to treat MDR-TB in several countries, despite the absence of randomised controlled clinical trials to assess efficacy, safety and tolerab ...
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Polysubstance dependence



A person with polysubstance dependence is psychologically addicted to being in an intoxicated state without a preference for one particular substance. Although any combination of three drugs can be used, studies have shown that alcohol is commonly used with another substance. This is supported by one study on polysubstance use that separated participants who used multiple substances into groups based on their preferred drug. The three substances were cocaine, alcohol, and heroin, which implies that those three are very popular. Other studies have found that opiates, cannabis, amphetamines, hallucinogens, inhalants and benzodiazepines are often used in combination as well. The results of a long-term or longitudinal study on substance use led the researchers to observe that excessively using or relying on one drug increased the probability of excessively using or relying on another drug.
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