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Anesthesia and Pulmonary Hypertension
Anesthesia and Pulmonary Hypertension

... in patients with PAH. 22 WHO clinical classification of pulmonary hypertension Table 2 outlines the updated World Health Organization (WHO) clinical classification of PH from the Dana Point meeting in 2008. 23 It is important to note that WHO Group 2 PH from LHF is managed very differently than PAH a ...
PDF ansehen - Deutsches Herzzentrum München
PDF ansehen - Deutsches Herzzentrum München

... to adult care is more effective and successful when the patient can be transferred within the same facility (5, 6). The availability of both adult and pediatric subspecialty providers improves your potential flexibility in identifying the right resources for your patient. In my experience having an ...
What is hypertrophic cardiomyopathy (HCM)?
What is hypertrophic cardiomyopathy (HCM)?

... The heart (specifically the left ventricle) may also thicken in other individuals who do not have HCM, either as a result of high blood pressure, obstructive heart valve disease, or even prolonged and intense athletic training in certain sports. The type of hypertrophy associated with high blood pre ...
Full-Text PDF - SciDoc Publishers
Full-Text PDF - SciDoc Publishers

... was claimed to be the third case of MI with pancreatitis. In 2010 Sheng-Hsiung Sheu reported a similar case where coronary angiography and elective PTCA was done after the recovery from pancreatitis [6]. Pancreatic proteolytic enzymes including trypsin may directly damage the membrane of the myocyte ...
ACCF/SCAI/AATS/AHA/ASE/ASNC/HFSA/HRS/SCCM/SCCT/SCMR
ACCF/SCAI/AATS/AHA/ASE/ASNC/HFSA/HRS/SCCM/SCCT/SCMR

... routinely conflict with AUC ratings, further evaluation of the specific clinical circumstances should be considered. The AUC development process itself is also evolving. Given the iterative nature of the process and incorporation of new information about the role for diagnostic and therapeutic inter ...
High-Resolution Magnetic Resonance Myocardial Perfusion
High-Resolution Magnetic Resonance Myocardial Perfusion

... functionally significant coronary artery stenosis as determined by FFR using both visual and quantitative analysis. CMR-based measurements of myocardial blood flow correlated better with FFR than with QCA. The majority of previous studies that have validated CMR myocardial perfusion imaging used QCA ...
Does prior coronary stenting compromise future coronary surgery?
Does prior coronary stenting compromise future coronary surgery?

... computed propensity score matching based on preoperative risk factors, in-hospital mortality remained higher among patients with previous PCI (OR: 3.46, 95% CI: 1.10–10.93; p = 0.034). Nevertheless, there are several studies in which no correlation between previous PCI and subsequent CABG has been f ...
ACC/AHA 2006 Guideline Update on
ACC/AHA 2006 Guideline Update on

... angina, symptomatic arrhythmias, hypertension, or other ACC/AHA Class I guideline indications. (Level of Evidence: C) 2. Beta blockers should be given to patients undergoing vascular surgery at high cardiac risk owing to the finding of ischemia on preoperative testing. (Level of Evidence: B) Class I ...
Copyright Information of the Article Published Online TITLE 12
Copyright Information of the Article Published Online TITLE 12

... addition, at baseline ECG, ER was present mainly in the inferior-lateral leads[10]. Tikkanen also considered the importance of defining a benign form of ER from a malignant one[35,36]. He studied a group of young athletes with ECG patterns of ER. Most of these presented an aspect of “rapidly ascendi ...
Alcohol Consumption and Binge Drinking as Risk Factors for
Alcohol Consumption and Binge Drinking as Risk Factors for

... Heavy alcohol consumption is associated with elevated risk for all-cause mortality compared to moderate drinking. Furthermore, the lower mortality related to moderate drinking is attributed to lower risk for coronary heart disease. Traditionally, alcohol consumption has been assessed in terms of ave ...
NCD Watch August 2016
NCD Watch August 2016

... Box 1: Major risk factors for atrial fibrillation Advancing age — Anyone can have atrial fibrillation, but the risk is greater as people age. For each advancing decade of age, the risk of developing atrial fibrillation are about doubled. 13 For example, men aged 75 to 79 were 2 times and more than 5 ...
Cardiac Disease Evaluation and Management Among Kidney and
Cardiac Disease Evaluation and Management Among Kidney and

... Level of Evidence C, this is, based on either weak evidence or the opinions of the working group. For example, this algorithm recommends that any patient on the kidney transplant waitlist with a history of diabetes mellitus or known CAD undergo noninvasive stress testing at baseline and then subsequ ...
effects of a randomized controlled trial of diet and/or exercise on
effects of a randomized controlled trial of diet and/or exercise on

... have left ventricular dysfunction are asymptomatic and are therefore undiagnosed 3. This increasing trend is, and will continue to be, a major public health concern. ...
Comparative Definitions for Moderate
Comparative Definitions for Moderate

... specific segments (i.e., anterior, lateral) would be problematic. These conceptual differences may promote a variable relationship between a threshold for moderate-severe ischemia and a given associated CAD event rate. ...
Congenital Heart Defects Left-to-Right Shunt Lesions by Prof Dr
Congenital Heart Defects Left-to-Right Shunt Lesions by Prof Dr

... • In the majority of people, the cause of congenital heart disease is unknown. However, there are some factors that are associated with an increased chance of getting congenital heart disease. These risk factors include: • Genetic or chromosomal abnormalities in the child such as Down syndrome. • Ta ...
JEPonline Physiological Responses to Dangling and Standing in
JEPonline Physiological Responses to Dangling and Standing in

... The SBP responses are consistent with previous reports by Dossa and Owens (10) and Kennedy and Crawford (19) but contrary to the results of McDaniel (25) where SBP decreased with dangling. We found no significant effect of dangling on DBP, which agrees with the results of Dossa and Owens (10) but is ...
Left Coronary Artery System – Angiographic Anatomy.
Left Coronary Artery System – Angiographic Anatomy.

... Main left Coronary artery is best viewed in the standard 300 right anterior oblique view. It is one of the shortest amongst the most important vessels of the body. In this view it is directed frontally and to the left. While still in space between the aorta and pulmonary artery, it divides into two ...
Delayed-enhancement cardiac MRI in the evaluation of
Delayed-enhancement cardiac MRI in the evaluation of

... layer, and in more severe ischemic damage can have a more complete gradient of transmurality, becoming a full-thickness scar (Table 1) . This pattern is secondary to the wavefront phenomenon of ischemic cell death [18] and characteristically occurs in the distribution corresponding to coronary arter ...
Clinical recommendations of cardiac magnetic resonance, Part II
Clinical recommendations of cardiac magnetic resonance, Part II

... The sensitivity of CMR for the diagnosis of myocarditis is high for infarct-like presentation, low for myocarditis with heart failure and with arrhythmic clinical presentation. CMR findings should be used cautiously in these two latter conditions.9 The persistence of inflammation in chronic myocardi ...
Factors Associated With Increased Risk for Dementia in Individuals
Factors Associated With Increased Risk for Dementia in Individuals

... vascular dementia, and Alzheimer´s disease to analyse factors from models related to an increased risk of dementia among persons with CHF using SAS Proc Mixed multilevel modelling. The GEE model is conceptually equivalent to logistic regression, but controls for the clustering of twins within a pair ...
Diminished physical capacity in obese individuals with normal left
Diminished physical capacity in obese individuals with normal left

... Two years ago, the deaths from heart disease were the first cause of death in Cuba, hence the increased mortality from 12.704 in 1970 to 22.234, in 2012, when it was second only to malignant tumors with 298 deaths more1. Risk factors for atherosclerosis, such as hypertension (HT), diabetes mellitus ...
When is ABP monitoring useful? - AURA Home
When is ABP monitoring useful? - AURA Home

... the management of hypertension emphasise that the necessity, choice and intensity of blood pressure (BP) lowering treatment should be determined by the individual’s probability of an event within a given period [absolute cardiovascular (CVD risk)][1]. The CVD risk is based on a thorough assessment o ...
Integrative Physiology
Integrative Physiology

... Abstract—Murine models of atherosclerosis, such as the apolipoprotein E (apoE) or the LDL receptor knockout mice, usually do not exhibit many of the cardinal features of human coronary heart disease (CHD), eg, spontaneous myocardial infarction, severe cardiac dysfunction, and premature death. Here w ...
Syncope in patients with structural heart disease
Syncope in patients with structural heart disease

... Review Click here for more articles from the SYNCOPE symposium ...
Hypertrophic Cardiomyopathy - Pathophysiology
Hypertrophic Cardiomyopathy - Pathophysiology

... myocardial contractility is normal in patients with HCM and so is not the cause of the decreased end-systolic volume. Instead the reduction in end-systolic volume is due to a decrease in afterload (systolic wall stress) brought on by the increase in wall thickness (explained by Laplace’s law). Left ...
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Cardiovascular disease



Cardiovascular disease (CVD) is a class of diseases that involve the heart or blood vessels. Cardiovascular disease includes coronary artery diseases (CAD) such as angina and myocardial infarction (commonly known as a heart attack). Other CVDs are stroke, hypertensive heart disease, rheumatic heart disease, cardiomyopathy, atrial fibrillation, congenital heart disease, endocarditis, aortic aneurysms, peripheral artery disease and venous thrombosis.The underlying mechanisms vary depending on the disease in question. Coronary artery disease, stroke, and peripheral artery disease involve atherosclerosis. This may be caused by high blood pressure, smoking, diabetes, lack of exercise, obesity, high blood cholesterol, poor diet, and excessive alcohol consumption, among others. High blood pressure results in 13% of CVD deaths, while tobacco results in 9%, diabetes 6%, lack of exercise 6% and obesity 5%. Rheumatic heart disease may follow untreated strep throat.It is estimated that 90% of CVD is preventable. Prevention of atherosclerosis is by decreasing risk factors through: healthy eating, exercise, avoidance of tobacco smoke and limiting alcohol intake. Treating high blood pressure and diabetes is also beneficial. Treating people who have strep throat with antibiotics can decrease the risk of rheumatic heart disease. The effect of the use of aspirin in people who are otherwise healthy is of unclear benefit. The United States Preventive Services Task Force recommends against its use for prevention in women less than 55 and men less than 45 years old; however, in those who are older it is recommends in some individuals. Treatment of those who have CVD improves outcomes.Cardiovascular diseases are the leading cause of death globally. This is true in all areas of the world except Africa. Together they resulted in 17.3 million deaths (31.5%) in 2013 up from 12.3 million (25.8%) in 1990. Deaths, at a given age, from CVD are more common and have been increasing in much of the developing world, while rates have declined in most of the developed world since the 1970s. Coronary artery disease and stroke account for 80% of CVD deaths in males and 75% of CVD deaths in females. Most cardiovascular disease affects older adults. In the United States 11% of people between 20 and 40 have CVD, while 37% between 40 and 60, 71% of people between 60 and 80, and 85% of people over 80 have CVD. The average age of death from coronary artery disease in the developed world is around 80 while it is around 68 in the developing world. Disease onset is typically seven to ten years earlier in men as compared to women.
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