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Coronary Sinus
Coronary Sinus

... showing any of the intimal hyperplasia of the coronary sinus system. The intima was a thin layer of endothelium (fig. 2E). The external elastic membrane was thin and the adventitia was composed of collagenous fibers. Sections taken from the interventricular septum showed structures comparable to tho ...
Practice Guideline: Focused Update
Practice Guideline: Focused Update

... which recommendations are based. In an effort to respond more quickly to new evidence, the American College of Cardiology/ American Heart Association (ACC/AHA) Task Force on Practice Guidelines has created a new “focused update” process to revise the existing guideline recommendations that are affec ...
Fellowship Handbook - Penn State Hershey
Fellowship Handbook - Penn State Hershey

... diagnosis and treat patients with a wide array of cardiac problems; these rotations are (1) a general cardiology service, (2) in an HV (heart and vascular) ICU housing patients with medical problems (acute myocardial infarction, acute coronary syndrome, arrhythmias) and surgical problems (post-op CA ...
Lipomatous Hypertrophy of the Interatrial Septum Accompanied By
Lipomatous Hypertrophy of the Interatrial Septum Accompanied By

... It is supported by studies that LHIS can induce arrhythmia and LHIS related p wave alterations, atrial arrhythmias and sudden cardiac deaths.8,10-13 The characteristic appearance of top and/or bottom part of interatrial septum which seems to be separated from foramen ovale is called as ‘dumbbell sha ...
Electrocardiographic criteria of left ventricular hypertrophy in general
Electrocardiographic criteria of left ventricular hypertrophy in general

... LVH diagnosed with the different ECG tests was always falsely low when compared to the gold standard (Fig. 2). In Table 3, the PPV and NPV of ECG tests are summarized. Before the age of 69 years, arterial hypertension predicted LVH diagnosed with the Sokolow–Lyon criterion in women (RR 4.10, CI 1.20 ...
AHA Scientific Statement
AHA Scientific Statement

... infant surgeries until the mid and late 1970s, when infant cardiopulmonary bypass (CPB) was in common use. The contemporary adult population of people with CHD is therefore made up of myriad populations with unique natural histories: those who survived without surgery; those who had repairs with mul ...
AHA Scientific Statement
AHA Scientific Statement

... infant surgeries until the mid and late 1970s, when infant cardiopulmonary bypass (CPB) was in common use. The contemporary adult population of people with CHD is therefore made up of myriad populations with unique natural histories: those who survived without surgery; those who had repairs with mul ...
PDF - Journal of Cardiovascular Magnetic Resonance
PDF - Journal of Cardiovascular Magnetic Resonance

... apex rotates anticlockwise in later systole. These opposing directions of rotation at the apex and base generate maximal torsional force at end systole [7]. It has been reported that athletes have decreased LV twist and torsion when compared to controls [5]. Both strain and torsion parameters can be ...
Effect of Endurance Exercise on Autonomic Control of Heart Rate
Effect of Endurance Exercise on Autonomic Control of Heart Rate

... is reduced by inputs from the motor cortex.[19] It is also possible that chronic endurance exercise can alter autonomic function and depress baroreflex control by decreasing baroreceptor sensitivity.[20] Smith et al.[20] found that sensitivity of the arterial baroreflex was significantly reduced in ...
Carotid arterial haemodynamics after mild degrees of lower
Carotid arterial haemodynamics after mild degrees of lower

... speed, even in the presence of a low original signalto-noise ratio. The present apparatus was substantially improved by the additional use of measurement of the Doppler shift, thus allowing a high degree of reproducibility to be achieved [7]. Indeed, during LBNP or tilt testing one can be certain th ...
Function and form in the developing cardiovascular system
Function and form in the developing cardiovascular system

... acquisition of functional parameters. It was shown that many functional aspects of the trabeculated heart are comparable with the adult heart, and the same parameters can be meaningfully determined after some modification of the equipment. Video recordings (Supplementary material online, Movie S3) o ...
Print - Circulation
Print - Circulation

... receiving or not receiving an angiotensin-converting enzyme inhibitor at baseline. Patients with serum creatinine ⱖ265 mmol/L; serum potassium ⱖ5.5 mmol/L; known bilateral renal artery stenosis; symptomatic hypotension; critical aortic or mitral stenosis; recent myocardial infarction, stroke, or ope ...
Special Report
Special Report

... such as systolic and diastolic heart failure, valvular heart disease, and myocardial infarction, and cardiovascular risk factors, such as hypertension, diabetes mellitus, obesity, and cigarette smoking.6,8,11–13 Subclinical markers indicating increased AF risk include increased arterial stiffness14 ...
guide to atrial fibrillation - Massachusetts General Hospital
guide to atrial fibrillation - Massachusetts General Hospital

... ATRIAL FIBRILLATION OVERVIEW An arrhythmia is an abnormal heart rhythm. The four chambers of the heart usually beat in a steady, rhythmic pattern. Atrial fibrillation (AF) occurs when the atria (the upper chambers of the heart) are fibrillating, or “quivering,” resulting in a rapid, irregular heart ...
Systolic and Diastolic Abnormalities Reduce the Cardiac Response
Systolic and Diastolic Abnormalities Reduce the Cardiac Response

... steatosis and increased left ventricular free fatty acid metabolism (22). It is therefore hypothesized that early interventions may prevent or delay changes in cardiac function and reduce the elevated risk of developing microvascular and macrovascular morbidity in adolescents with diabetes (21,23). ...
Prognostic value of electrocardiographic criteria for left ventricular
Prognostic value of electrocardiographic criteria for left ventricular

... Results During a mean follow-up of 7 F 4 years, in a total population of 19 434 patients (mean age 54 F 14 years), 1254 (6%) patients died of CV causes. The adjusted HR for CV mortality ranged from 1.4 (95% CI 1.2-1.6) to 3.7 (95% CI 2.7-5.0) among the various criteria. Left ventricular hypertrophy ...
Assessment of Coronary Microcirculation in a Swine Animal Model
Assessment of Coronary Microcirculation in a Swine Animal Model

... artery conditions by using both a flow probe as the gold standard and the angiographic ...
Cardiovascular Response to Breath-Holding Explained by Changes
Cardiovascular Response to Breath-Holding Explained by Changes

... systems plays a significant role [19]. Although there are some studies, which have analysed the functioning of the central and peripheral cardiovascular mechanisms, but the extent and sequence of activation of the central and peripheral regulatory mechanisms of the circulatory system, as well as the ...
AHA/ASA Guideline - Professional Heart Daily
AHA/ASA Guideline - Professional Heart Daily

... Statin therapy with intensive lipid-lowering effects is recommended to reduce risk of stroke and CV events among patients with ischemic stroke or TIA presumed to be of atherosclerotic origin and an LDL-C level ≥100 mg/dL with or without evidence for other ASCVD. (Class I, LOE B) Statin therapy with ...
Successful primary percutaneous coronary interventions
Successful primary percutaneous coronary interventions

... As per treatment protocol, before pPCI, the patient received oral administration of aspirin 300 mg, clopidogrel 600 mg and parenteral administration of unfractionated heparin 80 U per kilogram of body weight. On coronary angiography, a short LAD artery was seen, arising from the left coronary sinus ...
0474 ch 14(281-305).
0474 ch 14(281-305).

... in Figure 14-5 are colored blue because they are carrying deoxygenated blood, unlike other arteries, which carry oxygenated blood. 3. The left atrium receives blood high in oxygen content as it returns from the lungs in pulmonary veins. Note that the pulmonary veins in Figure 14-5 are colored red be ...
7: Stable Ischemic Heart Disease - Welcome to the CardioSource
7: Stable Ischemic Heart Disease - Welcome to the CardioSource

... implications in SIHD. For example, an elevated level of B­type natriuretic peptide (BNP) identifies a patient at an increased risk; however, there are no known treatment therapies that will reduce that risk. The lack of treatment implications has limited the incorporation of biomarkers into current  ...
2013 ESH/ESC Guidelines for the management of arterial
2013 ESH/ESC Guidelines for the management of arterial

... ESC Working Groups: Hypertension and the Heart, Cardiovascular Pharmacology and Drug Therapy ESC Councils: Cardiovascular Primary Care, Cardiovascular Nursing and Allied Professions, Cardiology Practice The content of these European Society of Cardiology (ESC) and European Society of Hypertension (E ...
Core Curriculum Coronary Artery Fistulas
Core Curriculum Coronary Artery Fistulas

... Transcatheter occlusion of a coronary artery fistula was first reported in 1983 [22]. Since then there have been multiple reports of series including up to 33 patients [18,23–28]. Results have generally been comparable with reported surgical results with an expected mortality rate of <1%. There have b ...
Seasonal Variation in Serum Cholesterol Levels
Seasonal Variation in Serum Cholesterol Levels

... ables) and ␹2 tests (for categorical variables). Longitudinal data were analyzed using mixed models (SAS Proc Mixed; SAS Institute Inc, Cary, NC) with restricted maximum likelihood methods.17 The primary outcome variables for the longitudinal analyses were the blood lipid measures. Two methods were ...
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Cardiovascular disease



Cardiovascular disease (CVD) is a class of diseases that involve the heart or blood vessels. Cardiovascular disease includes coronary artery diseases (CAD) such as angina and myocardial infarction (commonly known as a heart attack). Other CVDs are stroke, hypertensive heart disease, rheumatic heart disease, cardiomyopathy, atrial fibrillation, congenital heart disease, endocarditis, aortic aneurysms, peripheral artery disease and venous thrombosis.The underlying mechanisms vary depending on the disease in question. Coronary artery disease, stroke, and peripheral artery disease involve atherosclerosis. This may be caused by high blood pressure, smoking, diabetes, lack of exercise, obesity, high blood cholesterol, poor diet, and excessive alcohol consumption, among others. High blood pressure results in 13% of CVD deaths, while tobacco results in 9%, diabetes 6%, lack of exercise 6% and obesity 5%. Rheumatic heart disease may follow untreated strep throat.It is estimated that 90% of CVD is preventable. Prevention of atherosclerosis is by decreasing risk factors through: healthy eating, exercise, avoidance of tobacco smoke and limiting alcohol intake. Treating high blood pressure and diabetes is also beneficial. Treating people who have strep throat with antibiotics can decrease the risk of rheumatic heart disease. The effect of the use of aspirin in people who are otherwise healthy is of unclear benefit. The United States Preventive Services Task Force recommends against its use for prevention in women less than 55 and men less than 45 years old; however, in those who are older it is recommends in some individuals. Treatment of those who have CVD improves outcomes.Cardiovascular diseases are the leading cause of death globally. This is true in all areas of the world except Africa. Together they resulted in 17.3 million deaths (31.5%) in 2013 up from 12.3 million (25.8%) in 1990. Deaths, at a given age, from CVD are more common and have been increasing in much of the developing world, while rates have declined in most of the developed world since the 1970s. Coronary artery disease and stroke account for 80% of CVD deaths in males and 75% of CVD deaths in females. Most cardiovascular disease affects older adults. In the United States 11% of people between 20 and 40 have CVD, while 37% between 40 and 60, 71% of people between 60 and 80, and 85% of people over 80 have CVD. The average age of death from coronary artery disease in the developed world is around 80 while it is around 68 in the developing world. Disease onset is typically seven to ten years earlier in men as compared to women.
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