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Clinical Medicine Insights: Cardiology Arrhythmogenic Right
Clinical Medicine Insights: Cardiology Arrhythmogenic Right

... arrhythmia is sustained or nonsustained monomorphic VT that originates in the RV and therefore has a left bundle branch block (LBBB) morphology. Alternatively, in some cases where the LV is involved, VT could present with a right bundle branch block (RBBB) morphology. These symptoms are usually exer ...
Atrial Fibrillation: New Horizons
Atrial Fibrillation: New Horizons

... Most recently the segmental approach is preferred because the myocardial fibers surrounding the PV are not continuous. Segments where musculature is present can be identified using high frequency depolarization signals recorded through multi-electrode loop catheter or even conventional catheters. (C ...
Mechanisms With Clinical Implications for Atrial Fibrillation
Mechanisms With Clinical Implications for Atrial Fibrillation

... therapeutic target for CatK in vivo and in vitro. Methods and Results-—Plasma CatK and extracellular matrix protein peptides (intact procollagen type I of N-terminal propeptide; carboxyl-terminal telopeptide of type I collagen [ICTP]) were measured in 209 consecutive patients with AF (paroxysmal AF, ...
Pulse Wave Analysis
Pulse Wave Analysis

... With informed consent, 517 sets of testing data were collected from 318 subjects. The ages of subjects range from 1 to 91 years (mean ± SD, 55 ± 20). 87 subjects were chosen from normal people (mean ±SD, 51 ±17) and the rest were recorded from patients in Department of Cardiology at Shandong Provinc ...
Atrial Autonomic Innervation
Atrial Autonomic Innervation

... might lead to increased AF susceptibility (25). Ogawa et al. (36) have shown increased sympathetic and vagal nerve discharges before the onset of atrial arrhythmias in dogs with pacing-induced congestive heart failure by direct nerve recordings from the stellate ganglia and vagal nerves. Indeed, the ...
Echocardiographic Assessment of Diastolic Function
Echocardiographic Assessment of Diastolic Function

... completion of antegrade mitral flow. There are four distinct phases of diastole (Fig. 1): (1) isovolumetric ventricular relaxation: an active, adenosine triphosphate (ATP)-requiring process that occurs from endsystole until left ventricular pressure falls below left arterial pressure leading to mitr ...
Hypertension and arrhythmia: blood pressure control
Hypertension and arrhythmia: blood pressure control

... dysfunction of the left ventricle, left atrial size and function, and left ventricular hypertrophy have been suggested as the underlying risk factors for supraventricular and ventricular arrhythmias in hypertensives. Recently, several noninvasive electrocardiographic parameters have been defined and ...
Right Ventricular Compression as a Sign of Cardiac
Right Ventricular Compression as a Sign of Cardiac

... in the conventional echocardiographic study the right ventricular outflow tract remains patent, but the body of the right ventricle abruptly narrows below the level of the aortoseptal junction. Initially the anterior or free right ventricular wall is seen to be flat or slightly concave. The postperi ...
A Matter of the Heart: The African Clawed Frog Xenopus as a Model
A Matter of the Heart: The African Clawed Frog Xenopus as a Model

... currently the main tools in Xenopus research (see next section). With respect to MO based strategies and novel genome editing approaches, it is noteworthy to mention that Xenopus laevis is tetraploid whereas the related Xenopus tropicalis is diploid. 2. Tool Kit for Studying Heart Development and Di ...
Cardiac Amyloidosis
Cardiac Amyloidosis

... standing). Low blood platelets. Tingling and numbness in limbs (peripheral neuropathy). Muscle weakness. Cough, shortness of breath. Rarely, it may worsen heart failure. ...
Diagnosis of Stable Ischemic Heart Disease: Summary of a Clinical
Diagnosis of Stable Ischemic Heart Disease: Summary of a Clinical

... Methods: Literature on this topic published before November 2011 was identified by using MEDLINE, Embase, Cochrane CENTRAL, PsychINFO, AMED, and SCOPUS. Searches were limited to human studies published in English. This guideline grades the evidence and ...
Accessory Mitral Valve without Left Ventricular Outflow Tract
Accessory Mitral Valve without Left Ventricular Outflow Tract

... from the endocardial cushion during cardiac development.4,13,14 Because other types of left ventricular masses such as tumors (myxomas and papillary fibroelastomas) or vegetations can produce similar echocardiographic appearances, AMV should be considered in the differential diagnosis of a cardiac m ...
Patent ductus arteriosus in a lamb: A case report
Patent ductus arteriosus in a lamb: A case report

... arteriosus is detected with pulsed wave, continuous wave, or color flow Doppler echocardiography.2 Cardiac angiocardiography and nuclear angiocardiography using a selective aortic angiogram provide final evidence of a PDA. Oximetric data show a step-up in oxygen content or saturation in the pulmonar ...
Treatment of Ventricular Arrhythmias in Patients Undergoing LVAD
Treatment of Ventricular Arrhythmias in Patients Undergoing LVAD

... putting a man-made heart into a human being by the end of the decade (Sahuar 2004). Unlike the moon-landing, this lofty goal was not met. Nevertheless, progress proceeded slowly and clinical use of ventricular assist devices on a more routine basis began in the mid 1980s. Since then, the research an ...
Electrical Impedance of Normal and Ischemic Myocardium. Role on and Ventricular Arrhythmias.
Electrical Impedance of Normal and Ischemic Myocardium. Role on and Ventricular Arrhythmias.

... potential, action potential, conduction, refractoriness, automaticity, in the electrical passive properties, and finally the development of arrhythmias. Knowledge of the basic alterations taking place during acute and chronic infarction is mandatory for development of new diagnostic and therapeutic ...
Is L-Carnitine Effective in Reducing Mortality After an Acute
Is L-Carnitine Effective in Reducing Mortality After an Acute

... infarction. While the selected studies provided no definitive evidence that L-carnitine decreased long-term mortality rates post myocardial infarction but these studies did suggest that L-carnitine might be helpful with infarction size and early mortality rates. In the Singh study et al, total cardi ...
Evaluation of Left Coronary Artery Anatomy In Vitro by Cross
Evaluation of Left Coronary Artery Anatomy In Vitro by Cross

carl john wiggers - National Academy of Sciences
carl john wiggers - National Academy of Sciences

... One of the earliest of these lineages dealt with analyzing the interrelations of electrocardiographic, excitatory, contractile, and hemodynamic events during the cardiac cycle. This was not easy, because in the early 1900s it was necessary to import almost all research equipment of any intricacy fro ...
Vectorcardiographic Detection of Early Hemodynamic Abnormalities
Vectorcardiographic Detection of Early Hemodynamic Abnormalities

... particularly in those in group 2, was due to such chemical stimuli, since we observed only minimal changes in Pa02, PaC02, and pH during exercise in most of the patients. ...
cardiac muscle cells
cardiac muscle cells

... Figure 20–14b An Electrocardiogram: An ECG Printout Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings ...
Chest
Chest

... curvilinear medial margin of an emphysematous bleb in this patient with bullous emphysema. If multiple blebs coalesce they represent so-called “vanishing lung”. As they enlarge they also represent a danger of tension pneumothorax should one of them rupture. One of my instructors had that happen whil ...
Review Treatment of tachyarrhythmias during pregnancy and lactation
Review Treatment of tachyarrhythmias during pregnancy and lactation

... exercised with this class of drugs because excessive QT prolongation may cause torsade de pointes[28]; thus, QT duration should be monitored. Class IB drugs Lidocaine, used to manage ventricular tachycardia, particularly during myocardial ischaemia, is probably not teratogenic at clinically relevant ...
Congenital Heart Disease
Congenital Heart Disease

... affected, and up to 10% if two siblings are affected [1]. While prevention may need to await a better understanding of causal pathways, for affective treatment early detection and timely management are crucial. In this context, research has suggested that up to 25% of babies with severe forms of con ...
the mitral valve in endocardial cushion defects - Heart
the mitral valve in endocardial cushion defects - Heart

... These may also be heard in any condition in which the mitral cusp is displaced, such as mitral incompetence caused by ruptured chorde, and hypertrophic obstructive cardiomyopathy in which the mitral valve is distorted by the extreme muscular hypertrophy. INVESTIGATIONS Radiography. Marked cardiac en ...
Risk assessment in patients with an acute ST
Risk assessment in patients with an acute ST

... observational study on 2310 STEMI patients treated with primary PCI showed that increased heart rate on admission was an independent prognostic factor for in-hospital and long-term mortality [12,13] . The finding of a new murmur is an indicator of a structural complication of STEMI, which may lead t ...
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Electrocardiography



Electrocardiography (ECG or EKG*) is the process of recording the electrical activity of the heart over a period of time using electrodes placed on a patient's body. These electrodes detect the tiny electrical changes on the skin that arise from the heart muscle depolarizing during each heartbeat.In a conventional 12 lead ECG, ten electrodes are placed on the patient's limbs and on the surface of the chest. The overall magnitude of the heart's electrical potential is then measured from twelve different angles (""leads"") and is recorded over a period of time (usually 10 seconds). In this way, the overall magnitude and direction of the heart's electrical depolarization is captured at each moment throughout the cardiac cycle. The graph of voltage versus time produced by this noninvasive medical procedure is referred to as an electrocardiogram (abbreviated ECG or EKG).During each heartbeat, a healthy heart will have an orderly progression of depolarization that starts with pacemaker cells in the sinoatrial node, spreads out through the atrium, passes through the atrioventricular node down into the bundle of His and into the Purkinje fibers spreading down and to the left throughout the ventricles. This orderly pattern of depolarization gives rise to the characteristic ECG tracing. To the trained clinician, an ECG conveys a large amount of information about the structure of the heart and the function of its electrical conduction system. Among other things, an ECG can be used to measure the rate and rhythm of heartbeats, the size and position of the heart chambers, the presence of any damage to the heart's muscle cells or conduction system, the effects of cardiac drugs, and the function of implanted pacemakers.
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