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Dlg1 is required for myofibrillar arrangement in the
Dlg1 is required for myofibrillar arrangement in the

... embryos in which heartbeat starts at the 9-somite stage (Du et al., 2008). The heart consists of specialized contractile muscle cells called cardiomyocytes. Each cardiomyocyte houses many myofibrils, which consist of linearly arrayed contractile units called sarcomeres. To achieve heart contractions ...
"Artificial Heart Valves". In: Encyclopedia of Biomedical Engineering
"Artificial Heart Valves". In: Encyclopedia of Biomedical Engineering

... valvular architecture, or they are left unmounted (stentless) (Fig. 5) (14). To understand how these devices are created, a typical procedure for creating a pericardiumderived heart valve is shown in Fig. 6. Bovine pericardium (the external fibrous sac that encloses the heart) is collected at the sl ...
Cardiac Hypertrophy-Related Pathways in Obesity
Cardiac Hypertrophy-Related Pathways in Obesity

... The obese Zucker rat, a genetic model of morbid obesity, presents many of the same cardiopulmonary deficits noted in obese humans including respiratory control dysfunction (24, 25, 27), chest wall limitations (12), upper airway narrowing (34), hypertension (2), myocardial hypertrophy (13), cardiac a ...
Diminished Basal Phosphorylation Level of Phospholamban in the
Diminished Basal Phosphorylation Level of Phospholamban in the

... at its maximum and the heart is in a compensated stage with no evidence of heart failure. Our hemodynamic measurements at this stage showed a slight but insignificant decrease of 1dP/dt but a significantly higher left ventricular end-diastolic pressure. To investigate the basis of the diastolic dysf ...
The role of endomyocardial biopsy in the management of
The role of endomyocardial biopsy in the management of

... ventricular arrhythmia, and 3 focal neurological complications.18 Olsen, in an unpublished series referenced by Fowles and Mason,18 reported an overall complication rate of 1.55% in 3097 cardiomyopathy patients biopsied in Europe. Sekiguchi and Take19 reported a 1.17% complication rate in a worldwid ...
Assessment of the course of the great cardiac vein in a
Assessment of the course of the great cardiac vein in a

... Both the veins and the coronary arteries of the examined hearts were filled with the epoxy resin Polimal 100 and Polimal 150 and with the resin Durakryl. The application of the resin allowed the veins as well as the arteries to be visualised exactly. The epoxy resin was dissolved in the solvent and ...
CardioNet, Inc. v. MedNet Healthcare
CardioNet, Inc. v. MedNet Healthcare

... receiving a human assessment of a subset of the identified atrial fibrillation events; and based on the human assessment of the subset of the identified atrial fibrillation events, pictographically presenting, using a common time scale, information regarding the heart rate data for the multiple time ...
Myosin Types and Fiber Types in Cardiac Muscle I . Ventricular
Myosin Types and Fiber Types in Cardiac Muscle I . Ventricular

... atrial myosin (anti-bAm) antibodies reacted selectively with atrial myosin heavy chains, as determined by enzyme immunoassay combined with SDS-gel electrophoresis. In direct and indirect immunofluorescence assay, anti-bAm was found to stain all atrial muscle fibers and a minor proportion of ventricu ...
Clinical recommendations of cardiac magnetic resonance, Part II
Clinical recommendations of cardiac magnetic resonance, Part II

... LGE technique) are not part of the current task force criteria, because of lack of specificity, high interobserver variability, as well as some technical limitations, due to the thin RV wall thickness.32–36 LV abnormalities (diffuse or regional LV dysfunction, mid-wall or subepicardial LV LGE) are n ...
Peptidergic innervation of the excurrent ostia of two Orthopteroid
Peptidergic innervation of the excurrent ostia of two Orthopteroid

... about the morphology of the excurrent ostia of the locust, L. migratoria, and the stick insect, B. extradentatum. Seven pairs of excurrent ostia lie on the dorsal vessel of the migratory locust. One pair of these excurrent ostia is located on the mesothoracic ampullae and another pair on the metatho ...
1 Cold acclimation increases cardiac myofilament function and
1 Cold acclimation increases cardiac myofilament function and

... protein-level changes induced by cold acclimation and the resultant changes in whole heart ...
the value of the intracardiac echogenic foci in the fetal heart
the value of the intracardiac echogenic foci in the fetal heart

... During a 2 years period 190 pregnant women had been referred for fetal echocardiography. All ultrasound examinations had been performed on Aloka 1700 or Aloka 2000 SSD machine (Tokyo, Japan) by the transvaginal probe of 5 MHz or curved transducer with 3.5 MHz. Fetuses had been examined between 12 an ...
Heart smart mobstyle - The Heart Foundation
Heart smart mobstyle - The Heart Foundation

... BLM 1: What’s inside our bodies? . . . . . . . . . . . . . . . . . . . . . . . 10 BLM 2: Organs inside our bodies . . . . . . . . . . . . . . . . . . . . . . . 11 BLM 3: The human heart . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12 BLM 4: My heart notes . . . . . . . . . . . . . . ...
Influence of Patern and Degree of Left Ventricular Hypertrophy on
Influence of Patern and Degree of Left Ventricular Hypertrophy on

... factors (repeted expression of fetal genome isoforms, heme oxygenase-1[35]). These factors may differ in individual LVH forms. Measurement of left atrial size from the parasternal long axis view using the 2-dimensional “M-mode” method is limited in accuracy for LA size quantification because of the ...
AN ANALYSIS OF THE TOXIC ACTIONS OF PURIFIED STREP
AN ANALYSIS OF THE TOXIC ACTIONS OF PURIFIED STREP

... guinea pigs, rabbits, and rats were carried out in Chenoweth's solution (14); the bioassays on the guinea pig ileum, in Tyrode's solution. Both media were prepared daily from reagents of analytical grade in water redistUled over alkaline permanganate. Chenoweth's solution was continuously equilibrat ...
PDF - Circulation Research
PDF - Circulation Research

Left ventricular diastolic filling response to
Left ventricular diastolic filling response to

... in spite of the physiologic increase in the left ventricle radius-to-wall thickness ratio. Transmitral ventricular diastolic function has recently been recognized as an important component to the overall cardiac performance in normal adults and in patients with congestive heart failure. Determinatio ...
ardiovascular-system - bloodhounds Incorporated
ardiovascular-system - bloodhounds Incorporated

... and systemic circuits  Pulmonary circuit short, low-pressure circulation  Systemic circuit long, high-friction circulation  Anatomy of ventricles reflects differences  Left ventricle walls 3X thicker than right  Pumps with greater pressure ...
Targeting atrioventricular differences in ion channel properties for
Targeting atrioventricular differences in ion channel properties for

... (in control in the presence of carbachol or carbachol + 4-AP) were constructed as in previous studies,14 and the maximum DF (DFmax) was quantified as a function of time. The DF analysis allows for the quantification of how fast the functional re-entrant activity is at each point on the heart surface ...
Pathophysiology of right ventricular failure
Pathophysiology of right ventricular failure

... same mechanism causing LV dysfunction and also as a consequence of pulmonary hypertension secondary to elevated left-sided filling pressures in ischemic LV cardiomyopathy (5). RV failure may be an independent risk factor for morbidity and mortality in patients with left heart failure (6). RV failure ...
Echocardiographic assessment of diastolic function Steve R. Ommen, MD
Echocardiographic assessment of diastolic function Steve R. Ommen, MD

... Mitral valve inflow The pattern of MVI is well established as reflecting the pressure gradient between left atrium and left ventricle during diastolic filling. The change in the MVI pattern with advancing diastolic dysfunction has been described, particularly in those with concomitant systolic dysfu ...
Estudi de la regeneració miocàrdica en la
Estudi de la regeneració miocàrdica en la

... apoptosis and myocyte cell death by ethanol (Jänkalä et al, 2002; Molina et al, 2002; Fernández-Solà et al, 2006). However, not all excessive alcohol consumers develop significant myocardial damage, with some discordance between the high prevalence of alcohol consumption and the relative low inciden ...
Treatment of arrhythmogenic right ventricular
Treatment of arrhythmogenic right ventricular

... in patients undergoing ICD implantation.11,28 However, conflicting data exist concerning the role of inducibility of sustained VT or VF for prediction of long-term arrhythmic outcome in ARVC/D patients.22,23,25,26,33 Discrepancies between the study results may be explained by differences in arrhythm ...
Thrombolytics in Cardiac Arrest
Thrombolytics in Cardiac Arrest

... What is your current professional opinion on the use of thrombolytics during cardiopulmonary resuscitation (cardiac arrest)? 1. Would not recommend nor consider 2. Would consider in selected patients 3. Would consider in all patients when “all else fails” 4. I don't have enough information to make t ...
Strain Rate Imaging in Normal and Reduced Diastolic
Strain Rate Imaging in Normal and Reduced Diastolic

... Longitudinal M-mode image from the septum of a healthy subject (orientation as in Figure 2). Center, The same M-mode image in color Doppler tissue imaging (DTI). Bottom, The DTI and M-mode curves from the septal part of the mitral ring. Isovolumic contraction (IVC) is seen as a brief, nearly simulta ...
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Electrocardiography



Electrocardiography (ECG or EKG*) is the process of recording the electrical activity of the heart over a period of time using electrodes placed on a patient's body. These electrodes detect the tiny electrical changes on the skin that arise from the heart muscle depolarizing during each heartbeat.In a conventional 12 lead ECG, ten electrodes are placed on the patient's limbs and on the surface of the chest. The overall magnitude of the heart's electrical potential is then measured from twelve different angles (""leads"") and is recorded over a period of time (usually 10 seconds). In this way, the overall magnitude and direction of the heart's electrical depolarization is captured at each moment throughout the cardiac cycle. The graph of voltage versus time produced by this noninvasive medical procedure is referred to as an electrocardiogram (abbreviated ECG or EKG).During each heartbeat, a healthy heart will have an orderly progression of depolarization that starts with pacemaker cells in the sinoatrial node, spreads out through the atrium, passes through the atrioventricular node down into the bundle of His and into the Purkinje fibers spreading down and to the left throughout the ventricles. This orderly pattern of depolarization gives rise to the characteristic ECG tracing. To the trained clinician, an ECG conveys a large amount of information about the structure of the heart and the function of its electrical conduction system. Among other things, an ECG can be used to measure the rate and rhythm of heartbeats, the size and position of the heart chambers, the presence of any damage to the heart's muscle cells or conduction system, the effects of cardiac drugs, and the function of implanted pacemakers.
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