Materials and Methods - Frontiers in Bioscience
... 4.2. Effect of carnitine treatment on serum and tissue carnitine concentrations 4.3. Effect of carnitine treatment on blood pressure and cardiac hypertrophy 4.4. Effect of carnitine treatment on surrogate markers of renal function, anaemia and serum metabolites 4.5 Effect of carnitine treatment on m ...
... 4.2. Effect of carnitine treatment on serum and tissue carnitine concentrations 4.3. Effect of carnitine treatment on blood pressure and cardiac hypertrophy 4.4. Effect of carnitine treatment on surrogate markers of renal function, anaemia and serum metabolites 4.5 Effect of carnitine treatment on m ...
The onset of left ventricular diastolic dysfunction in SHR - AJP
... SERCA is regulated by its inhibitor phospholamban (PLB). Phosphorylation of PLB at Ser16 (p16-PLB) by protein kinase A and/or Thr17 by Ca2⫹/calmodulin-dependent kinase II reduces its inhibitory effects on SERCA, resulting in an increased affinity of SERCA for Ca2⫹, increasing SR Ca2⫹ uptake, whereas ...
... SERCA is regulated by its inhibitor phospholamban (PLB). Phosphorylation of PLB at Ser16 (p16-PLB) by protein kinase A and/or Thr17 by Ca2⫹/calmodulin-dependent kinase II reduces its inhibitory effects on SERCA, resulting in an increased affinity of SERCA for Ca2⫹, increasing SR Ca2⫹ uptake, whereas ...
The Enigma of the Fontan circulation Wolff, Djoeke
... MAL and syntaxins, in establishing and maintaining the myelin sheath Firstly, let us address the exercise tolerance in Fontan patients. The peak exercise tolerance, described as peak VO2index, is around 53- to 65% of predicted in Fontan patients compared to healthy individuals32-36. Despite the impa ...
... MAL and syntaxins, in establishing and maintaining the myelin sheath Firstly, let us address the exercise tolerance in Fontan patients. The peak exercise tolerance, described as peak VO2index, is around 53- to 65% of predicted in Fontan patients compared to healthy individuals32-36. Despite the impa ...
Myocardial Fatty Acid Metabolism in Health and Disease
... can range from almost 100% of the total energy requirement of the heart to being a minor contributor (46, 428, 449, 450, 538). An overview of the fatty acid -oxidative pathway is shown in Figure 2. Fatty acid use by the heart is dictated at many levels and is dependent on the source, concentration, ...
... can range from almost 100% of the total energy requirement of the heart to being a minor contributor (46, 428, 449, 450, 538). An overview of the fatty acid -oxidative pathway is shown in Figure 2. Fatty acid use by the heart is dictated at many levels and is dependent on the source, concentration, ...
3.3. Isolated heart perfusion
... Following 3 weeks of treatment, myocardial oxygen consumption (MVO 2) was unaffected in either group (23.5+/-1.6 versus 22.8+/-1.3 and 21.6+/-1.8 versus 24.8+/-2.9; untreated versus treated, control and uraemic groups respectively), but increased after 6 weeks treatment (17.7+/-0.8 versus 23.7+/-1.0 ...
... Following 3 weeks of treatment, myocardial oxygen consumption (MVO 2) was unaffected in either group (23.5+/-1.6 versus 22.8+/-1.3 and 21.6+/-1.8 versus 24.8+/-2.9; untreated versus treated, control and uraemic groups respectively), but increased after 6 weeks treatment (17.7+/-0.8 versus 23.7+/-1.0 ...
Mitral valve anatomy for Transcatheter techniques
... the closure while the longest distance occurred at Point 5 (7.78 ± 2.61 mm), as demonstrated in Figure basal zone that is found only in the mural leaflet is mal area that has insertions of basal cords to its v surface. Being distant from the ventricular wall, leaflet does not have attachments to bas ...
... the closure while the longest distance occurred at Point 5 (7.78 ± 2.61 mm), as demonstrated in Figure basal zone that is found only in the mural leaflet is mal area that has insertions of basal cords to its v surface. Being distant from the ventricular wall, leaflet does not have attachments to bas ...
Thermal adaptation of the crucian carp (Carassius carassius
... and winter were directly placed at acclimation temperatures of 18°C (warm-acclimation, WA) and 4°C (cold-acclimation, CA), respectively. Four weeks were allowed for thermal acclimation under a 15 h: 9 h light:dark photoperiod in the lab before experiments. WA crucian carp were fed three times a week ...
... and winter were directly placed at acclimation temperatures of 18°C (warm-acclimation, WA) and 4°C (cold-acclimation, CA), respectively. Four weeks were allowed for thermal acclimation under a 15 h: 9 h light:dark photoperiod in the lab before experiments. WA crucian carp were fed three times a week ...
Atrial natriuretic peptide (ANP)
... Quantitative studies on the granules were performed in various mammalian species (Jamieson and Palade, 1964; Cantin et al., 1979; Mifune et al., 1996), but authors do not agree on the number and diameter of the granules in the various regions of the atrial-auricular complex. In the rat, the larger n ...
... Quantitative studies on the granules were performed in various mammalian species (Jamieson and Palade, 1964; Cantin et al., 1979; Mifune et al., 1996), but authors do not agree on the number and diameter of the granules in the various regions of the atrial-auricular complex. In the rat, the larger n ...
Atrial Fibrillation - George Washington University School of Medicine
... doubles with each decade of adult life and ranges from 2 or 3 new cases per 1000 population per year between the ages of 55 and 64 years to 35 new cases per 1000 population per year between the ages of 85 and 94 years. The arrhythmia may be an independent risk factor for death, with a relative risk ...
... doubles with each decade of adult life and ranges from 2 or 3 new cases per 1000 population per year between the ages of 55 and 64 years to 35 new cases per 1000 population per year between the ages of 85 and 94 years. The arrhythmia may be an independent risk factor for death, with a relative risk ...
1 PULMONARY HYPERTENSION Robyn J. Barst, MD I
... capacity is lost, leading to increases in pulmonary artery pressure at rest and further elevations in pulmonary artery pressure with exercise. In response to this increased afterload, the right ventricle hypertrophies. Initially, the right ventricle is capable of sustaining normal cardiac output at ...
... capacity is lost, leading to increases in pulmonary artery pressure at rest and further elevations in pulmonary artery pressure with exercise. In response to this increased afterload, the right ventricle hypertrophies. Initially, the right ventricle is capable of sustaining normal cardiac output at ...
A STUDY OF CORONARY DOMINANCE
... A total of 50 adult hearts procured from dissection room cadavers from Department of Anatomy, preserved in 10% formalin, were included in this study irrespective of sex. The right and left coronary arteries (RCA, LCA) were traced by cleaning the epicardium and fat piecemeal. Their branches were diss ...
... A total of 50 adult hearts procured from dissection room cadavers from Department of Anatomy, preserved in 10% formalin, were included in this study irrespective of sex. The right and left coronary arteries (RCA, LCA) were traced by cleaning the epicardium and fat piecemeal. Their branches were diss ...
Stretch-mediated cardiac hypertrophy and extracellular matrix
... enlargement of the cross-sectional area of these cells, without effecting ventricular cavity dimensions7,8. This adaptive process is eventually accompanied by proliferation of non-cardiomyocytes (fibroblasts) and deposition of extracellular matrix (ECM) constituents such as collagens9,10. Further un ...
... enlargement of the cross-sectional area of these cells, without effecting ventricular cavity dimensions7,8. This adaptive process is eventually accompanied by proliferation of non-cardiomyocytes (fibroblasts) and deposition of extracellular matrix (ECM) constituents such as collagens9,10. Further un ...
Chapter 05: Junctional Rhythms Test Bank TRUE/FALSE 1. The AV
... OBJ: Describe the location, function, and (where appropriate) the intrinsic rate of the following structures: sinoatrial (SA) node, atrioventricular (AV) bundle, and Purkinje fibers. 12. If seen, the P wave of a rhythm originating in the AV junction will appear _____ in lead II. a. upright b. invert ...
... OBJ: Describe the location, function, and (where appropriate) the intrinsic rate of the following structures: sinoatrial (SA) node, atrioventricular (AV) bundle, and Purkinje fibers. 12. If seen, the P wave of a rhythm originating in the AV junction will appear _____ in lead II. a. upright b. invert ...
A ngiographic Study of Normal Coronary A rteries as First
... 2) Epicardium : some epicardial cells undergo an epithelial-mesenchymal transition induced by underlying myocardium . Mesenchymal cells contributed to the endothelial and smooth muscle cells of coronary arteries.(15,16,17) Neural crest also contributed to smooth muscle cells of proximal part of thes ...
... 2) Epicardium : some epicardial cells undergo an epithelial-mesenchymal transition induced by underlying myocardium . Mesenchymal cells contributed to the endothelial and smooth muscle cells of coronary arteries.(15,16,17) Neural crest also contributed to smooth muscle cells of proximal part of thes ...
acute rheumatic fever: current scenario in india
... criterion, ECHO evidence of carditis / valvulitis was seen in 46.9% of cases and the pediatricians had overlooked the carditis leading to under diagnosis of carditis in patients with arthralgia. This shows that in regions where ARF is endemic if arthralgia is taken as minor criteria and ECHO is not ...
... criterion, ECHO evidence of carditis / valvulitis was seen in 46.9% of cases and the pediatricians had overlooked the carditis leading to under diagnosis of carditis in patients with arthralgia. This shows that in regions where ARF is endemic if arthralgia is taken as minor criteria and ECHO is not ...
Eligibility and Disqualification Recommendations for Competitive
... variety of factors, particularly motivational attitudes. ...
... variety of factors, particularly motivational attitudes. ...
Catheter Ablation as Treatment for Atrial Fibrillation
... common focal trigger of AF appears to be located within the cardiac muscle that extends into the pulmonary veins. AF accounts for approximately one-third of hospitalizations for cardiac rhythm disturbances. Symptoms of AF (e.g., palpitations, decreased exercise tolerance, dyspnea) are primarily rela ...
... common focal trigger of AF appears to be located within the cardiac muscle that extends into the pulmonary veins. AF accounts for approximately one-third of hospitalizations for cardiac rhythm disturbances. Symptoms of AF (e.g., palpitations, decreased exercise tolerance, dyspnea) are primarily rela ...
images/Electrocardiography and Arrhythmia for Med Students.pps
... in subjects with normal hearts. ...
... in subjects with normal hearts. ...
Contemporary Echocardiography In Non
... Background: Non-ST elevation myocardial infarction (NSTEMI) has only recently been included in the definition of acute myocardial infarction and literature is limited regarding the usefulness of echocardiography as a diagnostic tool in this setting. Since analysis of regional wall motion abnormaliti ...
... Background: Non-ST elevation myocardial infarction (NSTEMI) has only recently been included in the definition of acute myocardial infarction and literature is limited regarding the usefulness of echocardiography as a diagnostic tool in this setting. Since analysis of regional wall motion abnormaliti ...
Congential Anomalies of the Coronary Arteries
... 9. Right ventricular outflow obstruction after a tunnel repair ...
... 9. Right ventricular outflow obstruction after a tunnel repair ...
Coronary arterial anomalies and variations
... or auxiliary role in the disease process? In order to produce unfavorable clinical conditions, are additional factors such as spasm, compression, hypertrophy, dysrhythmias or clotting disorders, required? Are these anomalies and their effect, ...
... or auxiliary role in the disease process? In order to produce unfavorable clinical conditions, are additional factors such as spasm, compression, hypertrophy, dysrhythmias or clotting disorders, required? Are these anomalies and their effect, ...
Accepted Manuscript
... North America, drugs that are not currently available in North America are discussed in the text without a specific COR. For studies performed in large numbers of subjects outside North America, each writing committee reviews the potential impact of different practice patterns and patient population ...
... North America, drugs that are not currently available in North America are discussed in the text without a specific COR. For studies performed in large numbers of subjects outside North America, each writing committee reviews the potential impact of different practice patterns and patient population ...
Guidelines on the Diagnosis and Management of Pericardial Diseases
... causing no haemodynamic compromise pericardiocentesis is indicated in effusions >20 mm in echocardiography in diastole29 or for diagnostic purposes if additional procedures are available (e.g., pericardial fluid and tissue analyses, pericardioscopy, and epicardial/pericardial biopsy) which could reve ...
... causing no haemodynamic compromise pericardiocentesis is indicated in effusions >20 mm in echocardiography in diastole29 or for diagnostic purposes if additional procedures are available (e.g., pericardial fluid and tissue analyses, pericardioscopy, and epicardial/pericardial biopsy) which could reve ...
Guidelines on the Diagnosis and Management of Pericardial Diseases
... causing no haemodynamic compromise pericardiocentesis is indicated in effusions >20 mm in echocardiography in diastole29 or for diagnostic purposes if additional procedures are available (e.g., pericardial fluid and tissue analyses, pericardioscopy, and epicardial/pericardial biopsy) which could reve ...
... causing no haemodynamic compromise pericardiocentesis is indicated in effusions >20 mm in echocardiography in diastole29 or for diagnostic purposes if additional procedures are available (e.g., pericardial fluid and tissue analyses, pericardioscopy, and epicardial/pericardial biopsy) which could reve ...
Arrhythmogenic right ventricular dysplasia
Arrhythmogenic right ventricular dysplasia (ARVD), also called arrhythmogenic right ventricular cardiomyopathy (ARVC) or arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C), is an inherited heart disease.ARVD is caused by genetic defects of the parts of heart muscle (also called myocardium or cardiac muscle) known as desmosomes, areas on the surface of heart muscle cells which link the cells together. The desmosomes are composed of several proteins, and many of those proteins can have harmful mutations.The disease is a type of nonischemic cardiomyopathy that involves primarily the right ventricle. It is characterized by hypokinetic areas involving the free wall of the right ventricle, with fibrofatty replacement of the right ventricular myocardium, with associated arrhythmias originating in the right ventricle.ARVD can be found in association with diffuse palmoplantar keratoderma, and woolly hair, in a autosomal recessive condition called Naxos disease, because this genetic abnormality can affect also the integrity of the superficial layers of the skin most exposed to pressure stress.ARVC/D is an important cause of ventricular arrhythmias in children and young adults. It is seen predominantly in males, and 30-50% of cases have a familial distribution.