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Lesson 1
Lesson 1

... too little or no insulin, resulting in high blood glucose levels. Symptoms include fatigue, weight loss, thirst, and frequent urination. ...
Genotype Versus Phenotype in Families with Androgen Insensitivity
Genotype Versus Phenotype in Families with Androgen Insensitivity

... commonly accepted concept of dependence on fetal androgens of the development of Wolffian ducts was studied in complete androgen insensitivity syndrome (CAIS) patients. In a nationwide survey in The Netherlands, all cases (n ⴝ 49) with the presumptive diagnosis androgen insensitivity syndrome known ...
Dear Notetaker:
Dear Notetaker:

... - Stored in secretory vesicles until needed When endocrine cell is activated - Vesicle fuses with plasma membrane, active hormones are released via exocytosis - Inactive fragments also released o Most are biologically inactive, but there are instances where some of them do have biological activity ( ...
Relationship Between Circulating Cortisol and Testosterone
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... coefficient is statistically significant (p<0.05). from physical exercise. Previous research had found that pharmacologically manipulated levels of cortisol had resulted in reductions in circulating testosterone (i.e., a negative relationship) (Bambino and Hsueh, 1981; Cumming et al., 1983). We hypo ...
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Endocrine system

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Bio 100-Ch 15
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Hyperandrogenism

Hyperandrogenism, or androgen excess, is a medical condition characterized by excessive levels of androgens in the body and the associated effects of these excessive levels of androgens.Hyperandrogenism is one of the primary symptoms of polycystic ovary syndrome (PCOS). In such cases, it presents with symptoms such as acne and seborrhea, is frequent in adolescent girls and is often associated with irregular menstrual cycles. In most instances, these symptoms are transient and reflect only the immaturity of the hypothalamic-pituitary-ovarian axis during the first years following menarche. Approximately three-quarters of patients with PCOS (by the diagnostic criteria of NIH/NICHD 1990) have evidence of hyperandrogenism, with free testosterone being the single most predictive marker with ~60% of patients demonstrating supranormal levels.Hyperandrogenism can also be the result of excessive production of adrenal or gonadal androgens by adrenal adenomas, carcinomas, or hyperplasia, Leydig cell tumors in men, and arrhenoblastomas in women.In women, signs and symptoms of hyperandrogenism frequently include acne, scalp hair loss (androgenic alopecia), excessive facial and body hair (hirsutism), atypically high libido, breast atrophy, and others. Collectively, these symptoms are described as virilization.Management of hyperandrogenism symptoms like androgenic alopecia, include the use of antiandrogens such as cyproterone acetate, spironolactone, and flutamide.
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