Robert Friedland - ICAD-Me
... • We have more nucleotide sequences in our gut than in our own cells • We evolved with these organisms – they are not there “by accident” • Evolutionary conserved proteins are widespread and can lead to diseases via molecular mimicry through similarity of tertiary structures • Gut bacteria may be in ...
... • We have more nucleotide sequences in our gut than in our own cells • We evolved with these organisms – they are not there “by accident” • Evolutionary conserved proteins are widespread and can lead to diseases via molecular mimicry through similarity of tertiary structures • Gut bacteria may be in ...
Review Article Thyroid dysfunction: an autoimmune aspect
... dendritic cells) belonging to major histocompatibility complex (MHC) class II, especially dendritic cells, accumulate within the thyroid gland and present specific thyroid antigens to lymphocytes, which leads to activation and proliferation of auto-reactive B and T lymphocytes. Thus, activated antig ...
... dendritic cells) belonging to major histocompatibility complex (MHC) class II, especially dendritic cells, accumulate within the thyroid gland and present specific thyroid antigens to lymphocytes, which leads to activation and proliferation of auto-reactive B and T lymphocytes. Thus, activated antig ...
Inflammation in the Bovine Female Reproductive Tract
... condition is thought to be the result of a failure of the damaged endometrium to terminate the luteal phase ( i.e., a failure t o release appropriate bursts of PGF2,) ( 4 3 ) . Pyometra is most common in postpartum cows that have ovulated at least once following calving. It can also occur in natural ...
... condition is thought to be the result of a failure of the damaged endometrium to terminate the luteal phase ( i.e., a failure t o release appropriate bursts of PGF2,) ( 4 3 ) . Pyometra is most common in postpartum cows that have ovulated at least once following calving. It can also occur in natural ...
Antibiotics and Medicine - e-Bug
... Due to media attention MRSA is one of the most commonly known antibiotic resistant bacteria. What is being done in hospitals to tackle this problem? ...
... Due to media attention MRSA is one of the most commonly known antibiotic resistant bacteria. What is being done in hospitals to tackle this problem? ...
Secretion by Human Monocytes Inducers of
... intestine, where it quickly penetrates the epithelium. A clinically asymptomatic incubation period of 8 to 14 days ensues until clinical onset of typhoid fever, characterized by symptoms that include fever and malaise and by a sustained, low-level bacteremia (17, 18, 22). The mechanisms leading to t ...
... intestine, where it quickly penetrates the epithelium. A clinically asymptomatic incubation period of 8 to 14 days ensues until clinical onset of typhoid fever, characterized by symptoms that include fever and malaise and by a sustained, low-level bacteremia (17, 18, 22). The mechanisms leading to t ...
NIH Public Access - Pensiero Critico
... was the lack of understanding of cardiovascular disease that the following year the President-elect chose an ear, nose, throat specialist, Admiral Ross McIntyre, as his personal physician since it was felt that headaches and sinus problems would be the primary future health concern.7 Between 1935 to ...
... was the lack of understanding of cardiovascular disease that the following year the President-elect chose an ear, nose, throat specialist, Admiral Ross McIntyre, as his personal physician since it was felt that headaches and sinus problems would be the primary future health concern.7 Between 1935 to ...
Document
... Most of the following organisms are normal skin flora. 1. S. epidermidis, 2. other coagulase –ve Staphylococci. 3. Corynebacterium sp. 4. Brevibacterium sp. 5. Proprionibacterium acnes ...
... Most of the following organisms are normal skin flora. 1. S. epidermidis, 2. other coagulase –ve Staphylococci. 3. Corynebacterium sp. 4. Brevibacterium sp. 5. Proprionibacterium acnes ...
Neonatal Chlamydial Infection Induces Mixed T-Cell
... Measurements and Main Results: Mild Chlamydia-induced lung disease was observed 10–15 days after infection, as evidenced by increased bacterial numbers and histopathology in the lung and a reduction in weight gain. After 6 weeks, infection and histopathology had resolved and the rate of weight gain ...
... Measurements and Main Results: Mild Chlamydia-induced lung disease was observed 10–15 days after infection, as evidenced by increased bacterial numbers and histopathology in the lung and a reduction in weight gain. After 6 weeks, infection and histopathology had resolved and the rate of weight gain ...
Lung inflammatory responses
... system, and cytokines which further increase the inflammation present in the area. All of these events diminish the ability of the lungs to exchange gases, making them life threatening to the host animal. Inflammatory responses can be categorized as acute and chronic in nature. Each of the inflammat ...
... system, and cytokines which further increase the inflammation present in the area. All of these events diminish the ability of the lungs to exchange gases, making them life threatening to the host animal. Inflammatory responses can be categorized as acute and chronic in nature. Each of the inflammat ...
Prognostic Value of a Novel Classification Scheme for Heart Failure
... Heart failure is a major public health problem affecting over five million persons in the United States and over 23 million worldwide (1). The epidemiologic study of heart failure, however, has been partly impeded by the absence of a universally agreed-upon case definition (2–12). Though numerous ca ...
... Heart failure is a major public health problem affecting over five million persons in the United States and over 23 million worldwide (1). The epidemiologic study of heart failure, however, has been partly impeded by the absence of a universally agreed-upon case definition (2–12). Though numerous ca ...
An Intrinsic Pathogenicity Index for Microorganisms
... tract of a patient to cause infection in that patient. The index derived for a particular microorganismis applicable to a specific patient population. The range of the IPI is 0-1. An IPI of 1 denotes a microorganism which, after colonising a patient, will always cause infection. Such an organism may ...
... tract of a patient to cause infection in that patient. The index derived for a particular microorganismis applicable to a specific patient population. The range of the IPI is 0-1. An IPI of 1 denotes a microorganism which, after colonising a patient, will always cause infection. Such an organism may ...
THE CARDIOVASCULAR HISTORY AND PHYSICAL EXAMINATION
... It is a superficial scratching , high pitched sound, comparable with creaking leather, best heard with the diaphragm of the stethoscope Often has systolic and diastolic components. It may be audible over any part of the precordium ,usually heard best in the 3rd interspace to the left of the sternum ...
... It is a superficial scratching , high pitched sound, comparable with creaking leather, best heard with the diaphragm of the stethoscope Often has systolic and diastolic components. It may be audible over any part of the precordium ,usually heard best in the 3rd interspace to the left of the sternum ...
Lung inflammatory responses
... system, and cytokines which further increase the inflammation present in the area. All of these events diminish the ability of the lungs to exchange gases, making them life threatening to the host animal. Inflammatory responses can be categorized as acute and chronic in nature. Each of the inflammat ...
... system, and cytokines which further increase the inflammation present in the area. All of these events diminish the ability of the lungs to exchange gases, making them life threatening to the host animal. Inflammatory responses can be categorized as acute and chronic in nature. Each of the inflammat ...
What is Atrial Fibrillation?
... This is an atrial fibrillation that has started suddenly, or has made symptoms get worse. This could be a recent-onset atrial fibrillation (AF) - it has happened for the first time - or the patient may have had AF before. Acute-onset AF can occur in patients with either persistent or paroxysmal AF, ...
... This is an atrial fibrillation that has started suddenly, or has made symptoms get worse. This could be a recent-onset atrial fibrillation (AF) - it has happened for the first time - or the patient may have had AF before. Acute-onset AF can occur in patients with either persistent or paroxysmal AF, ...
Assessment of Cardiac Allograft Vasculopathy in Cardiac
... Within the first 30 days following cardiac transplantation, primary failure of the cardiac allograft can have many causes. But, over time, once the initial mortality of the first six months is overcome, allograft failure can be most often associated with chronic injury caused by immune-mediated reje ...
... Within the first 30 days following cardiac transplantation, primary failure of the cardiac allograft can have many causes. But, over time, once the initial mortality of the first six months is overcome, allograft failure can be most often associated with chronic injury caused by immune-mediated reje ...
a pulsatile bioreactor for conditioning tissue engineered heart valves
... physiological intra-cardiac pressures and flow will stimulate stem cells to differentiate and remodel valvular scaffold constructs before implantation. The group developed a pneumatic-driven conditioning system (Aim I) consisting of a three-chambered heart valve bioreactor, a pressurized compliance ...
... physiological intra-cardiac pressures and flow will stimulate stem cells to differentiate and remodel valvular scaffold constructs before implantation. The group developed a pneumatic-driven conditioning system (Aim I) consisting of a three-chambered heart valve bioreactor, a pressurized compliance ...
personal identification and authentication by using “the way
... First, a fine powder is used to enhance the latent fingerprints left on a glass or scanner surface. Then, a photo of the print is taken which is used to transfer the print to a PCB (Printed Circuit Board). UV light exposure and acid etching leaves the profile of the print on the board, which is used ...
... First, a fine powder is used to enhance the latent fingerprints left on a glass or scanner surface. Then, a photo of the print is taken which is used to transfer the print to a PCB (Printed Circuit Board). UV light exposure and acid etching leaves the profile of the print on the board, which is used ...
Cardiac Murmurs
... Systolic ejection murmurs. These are described as crescendo- decrescendo murmurs; their intensity peaks in early or mid systole(see Figure 2). Ejection murmurs result from some type of outflow obstruction. Important causes include aortic stenosis, pulmonary stenosis, and hypertrophic obstructive car ...
... Systolic ejection murmurs. These are described as crescendo- decrescendo murmurs; their intensity peaks in early or mid systole(see Figure 2). Ejection murmurs result from some type of outflow obstruction. Important causes include aortic stenosis, pulmonary stenosis, and hypertrophic obstructive car ...
Problems - Heart Failure Society of America
... Atrial fibrillation is an irregular and often a rapid heart rhythm in the upper chambers of the heart. It occurs when many electrical impulses are generated signaling your heart to beat instead of the single impulse in the sinus node that usually starts the beat. Atrial fibrillation is the most comm ...
... Atrial fibrillation is an irregular and often a rapid heart rhythm in the upper chambers of the heart. It occurs when many electrical impulses are generated signaling your heart to beat instead of the single impulse in the sinus node that usually starts the beat. Atrial fibrillation is the most comm ...
Effective Closure of the Mitral Valve without Atrial Systole
... was made possible by a mechanical marker in the radiologic field whose movement was triggered by the electrocardiogram. In some studies, the Cinetrace,* a device which permits recording of the electrocardiogram and other oscilloscopic data directly on the cine film,15 was used. Normal sinus rhythm w ...
... was made possible by a mechanical marker in the radiologic field whose movement was triggered by the electrocardiogram. In some studies, the Cinetrace,* a device which permits recording of the electrocardiogram and other oscilloscopic data directly on the cine film,15 was used. Normal sinus rhythm w ...
Congenital Heart Defects Left-to-Right Shunt Lesions by Prof Dr
... that are associated with an increased chance of getting congenital heart disease. These risk factors include: • Genetic or chromosomal abnormalities in the child such as Down syndrome. • Taking certain medications or alcohol or drug abuse during pregnancy. • Maternal viral infection, such as rubella ...
... that are associated with an increased chance of getting congenital heart disease. These risk factors include: • Genetic or chromosomal abnormalities in the child such as Down syndrome. • Taking certain medications or alcohol or drug abuse during pregnancy. • Maternal viral infection, such as rubella ...
Pathophysiological role and clinical relevance of cytokines
... in the last decade since the introduction of ACE-inhibitors and β-adrenergic receptor blockers in the management of heart failure, chronic heart failure is still one of the most important causes of morbidity and mortality and has a very high frequency for readmission to hospitalization because of th ...
... in the last decade since the introduction of ACE-inhibitors and β-adrenergic receptor blockers in the management of heart failure, chronic heart failure is still one of the most important causes of morbidity and mortality and has a very high frequency for readmission to hospitalization because of th ...
Systemic Lupus Erythematosus - UC Irvine`s Department of Medicine
... women doubles their risk Treatment of clinically stable SLE with oral contraceptives for one year does not increase disease flares ...
... women doubles their risk Treatment of clinically stable SLE with oral contraceptives for one year does not increase disease flares ...
5.5_antibodies
... to treat cancer Targeting medication to specific cell types by attaching a therapeutic drug to an antibody is one way to treat cancer. There are however many more. Ways Monoclonal antibodies can be used to treat cancer ...
... to treat cancer Targeting medication to specific cell types by attaching a therapeutic drug to an antibody is one way to treat cancer. There are however many more. Ways Monoclonal antibodies can be used to treat cancer ...
Rheumatic fever
Rheumatic fever, also known as acute rheumatic fever (ARF), is an inflammatory disease that can involve the heart, joints, skin, and brain. The disease typically develops two to four weeks after a throat infection. Signs and symptoms include fever, multiple painful joints, involuntary muscle movements, and a characteristic but uncommon non itchy rash known as erythema marginatum. The heart is involved in about half of cases. Permanent damage to the heart valves, known as rheumatic heart disease (RHD), usually only occurs after multiple attacks but may occasionally occur after a single case of ARF. The damaged valves may result in heart failure. The abnormal valves also increase the risk of the person developing atrial fibrillation and infection of the valves.Acute rheumatic fever may occur following an infection of the throat by the bacteria Streptococcus pyogenes. If it is untreated ARF occurs in up to three percent of people. The underlying mechanism is believed to involve the production of antibodies against a person's own tissues. Some people due to their genetics are more likely to get the disease when exposed to the bacteria than others. Other risk factors include malnutrition and poverty. Diagnosis of ARF is often based on the presence of signs and symptoms in combination with evidence of a recent streptococcal infection.Treating people who have strep throat with antibiotics, such as penicillin, decreases their risk of getting ARF. This often involves testing people with sore throats for the infection, which may not be available in the developing world. Other preventative measures include improved sanitation. In those with ARF and RHD prolonged periods of antibiotics are sometimes recommended. Gradual return to normal activities may occur following an attack. Once RHD develops, treatment is more difficult. Occasionally valve replacement surgery or repair is required. Otherwise complications are treated as per normal.Acute rheumatic fever occurs in about 325,000 children each year and about 18 million people currently have rheumatic heart disease. Those who get ARF are most often between the ages of 5 and 14, with 20% of first-time attacks occurring in adults. The disease is most common in the developing world and among indigenous peoples in the developed world. In 2013 it resulted in 275,000 deaths down from 374,000 deaths in 1990. Most deaths occur in the developing world where as many as 12.5% of people affected may die each year. Descriptions of the condition are believed to date back to at least the 5th century BCE in the writings of Hippocrates. The disease is so named because its symptoms are similar to those of some rheumatic disorders.