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Peptidergic innervation of the excurrent ostia of two Orthopteroid
Peptidergic innervation of the excurrent ostia of two Orthopteroid

... staining), and also be a site of release for proctolin. Very little is known about these unique structures. Nutting [3] has described their presence in Orthopteroid insects (9 orders, 5 suborders, 48 families) and shown that they are ovate openings in the dorsal vessel wall that appear as opaque whi ...
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Name That Murmur — Eponyms for the Astute
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Common Childhood Infections
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... differentiation and outcome of human infection, factors that regulate T-cell differentiation and Th1/Th2 cytokine responses in asymptomatic infection, active and historical chronic infection and recurrent cutaneous leishmaniasis were examined. By employing PBMCs, an inverse correlation was observed ...
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The use of qualitative cultures for detecting infection in open tibial

... almost 84%. Invasive procedures such as repeated debridement and multiple antibiotic therapy were performed, based mainly on the clinical status of the wound and patient’s condition (not positive culture). Postdebridement cultures yielded good specificity; if an open fracture wound did not display a ...
Transcript
Transcript

... renin angiotensin system with ACE inhibitors and ARBs. And, this is just a slide reviewing a number of trials, heart failure, hypertension, arrhythmia trials in which the risk of developing atrial fibrillation was reduced with ACE inhibitors and ARBs. So, this is a well-established target in the pro ...
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Rheumatic fever



Rheumatic fever, also known as acute rheumatic fever (ARF), is an inflammatory disease that can involve the heart, joints, skin, and brain. The disease typically develops two to four weeks after a throat infection. Signs and symptoms include fever, multiple painful joints, involuntary muscle movements, and a characteristic but uncommon non itchy rash known as erythema marginatum. The heart is involved in about half of cases. Permanent damage to the heart valves, known as rheumatic heart disease (RHD), usually only occurs after multiple attacks but may occasionally occur after a single case of ARF. The damaged valves may result in heart failure. The abnormal valves also increase the risk of the person developing atrial fibrillation and infection of the valves.Acute rheumatic fever may occur following an infection of the throat by the bacteria Streptococcus pyogenes. If it is untreated ARF occurs in up to three percent of people. The underlying mechanism is believed to involve the production of antibodies against a person's own tissues. Some people due to their genetics are more likely to get the disease when exposed to the bacteria than others. Other risk factors include malnutrition and poverty. Diagnosis of ARF is often based on the presence of signs and symptoms in combination with evidence of a recent streptococcal infection.Treating people who have strep throat with antibiotics, such as penicillin, decreases their risk of getting ARF. This often involves testing people with sore throats for the infection, which may not be available in the developing world. Other preventative measures include improved sanitation. In those with ARF and RHD prolonged periods of antibiotics are sometimes recommended. Gradual return to normal activities may occur following an attack. Once RHD develops, treatment is more difficult. Occasionally valve replacement surgery or repair is required. Otherwise complications are treated as per normal.Acute rheumatic fever occurs in about 325,000 children each year and about 18 million people currently have rheumatic heart disease. Those who get ARF are most often between the ages of 5 and 14, with 20% of first-time attacks occurring in adults. The disease is most common in the developing world and among indigenous peoples in the developed world. In 2013 it resulted in 275,000 deaths down from 374,000 deaths in 1990. Most deaths occur in the developing world where as many as 12.5% of people affected may die each year. Descriptions of the condition are believed to date back to at least the 5th century BCE in the writings of Hippocrates. The disease is so named because its symptoms are similar to those of some rheumatic disorders.
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