Template to create a scientific poster
... mucosa, are taken up by maternal tolerogenic APCs and presented on MHC class II molecules through the indirect pathway to cause the differentiation of naïve T cells with cognate TCR specificity to iTregs. Although paternal class I and mHAgs are also variably present, initial indirect presentation to ...
... mucosa, are taken up by maternal tolerogenic APCs and presented on MHC class II molecules through the indirect pathway to cause the differentiation of naïve T cells with cognate TCR specificity to iTregs. Although paternal class I and mHAgs are also variably present, initial indirect presentation to ...
Immunology
... mannose-binding lectin (MBL) to mannose residues on glycoproteins or carbohydrates on the surface of microorganisms including certain Salmonella, Listeria, and Neisseria strains, as well as Cryptococcus neoformans and Candida albicans. MBL is an acute phase protein produced in inflammatory responses ...
... mannose-binding lectin (MBL) to mannose residues on glycoproteins or carbohydrates on the surface of microorganisms including certain Salmonella, Listeria, and Neisseria strains, as well as Cryptococcus neoformans and Candida albicans. MBL is an acute phase protein produced in inflammatory responses ...
The role of the cell wall in fungal pathogenesis
... 2008). Pattern recognition receptors are differentially expressed in the surface of immune cells (Fig. 3). Phagocytes are essential components of the innate system in the control of the fungal infection as they contribute to eliminate the microbe. They comprise both monocytes and neutrophils in the ...
... 2008). Pattern recognition receptors are differentially expressed in the surface of immune cells (Fig. 3). Phagocytes are essential components of the innate system in the control of the fungal infection as they contribute to eliminate the microbe. They comprise both monocytes and neutrophils in the ...
Immune escape from a graft-versus-leukemia effect may play a role
... respectively). There was no change in the target susceptibility in patients P3 and P4. In patient P2, incubation of the post-transplant but not the pre-transplant leukemia targets with IFN-g induced an increase in the lysis of the posttransplant leukemia to almost pre-BMT levels (E:T at 24:1 rose fr ...
... respectively). There was no change in the target susceptibility in patients P3 and P4. In patient P2, incubation of the post-transplant but not the pre-transplant leukemia targets with IFN-g induced an increase in the lysis of the posttransplant leukemia to almost pre-BMT levels (E:T at 24:1 rose fr ...
Cytokines
... Cytokines in Therapy of Diseases Since cytokines have potent activities at low concentrations in controlling responses of host cells to normal and pathological events, can we use Cytokines deliberately in therapy? ...
... Cytokines in Therapy of Diseases Since cytokines have potent activities at low concentrations in controlling responses of host cells to normal and pathological events, can we use Cytokines deliberately in therapy? ...
Diapositive 1 - UJF) Grenoble
... - Monocyte capacity to release TNF in response to LPS challenge - Lymphocyte proliferation in response to recall antigens or mitogens - Phagocytosis, chemotaxis…. - Time consuming (days of incubation for lymphocyte proliferation), - Home-made protocols => difficult to standardize => Not suitable for ...
... - Monocyte capacity to release TNF in response to LPS challenge - Lymphocyte proliferation in response to recall antigens or mitogens - Phagocytosis, chemotaxis…. - Time consuming (days of incubation for lymphocyte proliferation), - Home-made protocols => difficult to standardize => Not suitable for ...
on Immune Function
... and macrophages to phagocytize invading organisms is another type of defense. Cellmediated responses of the T cells and natural killer (NK) cells play a crucial role in controlling invading organisms as do the antibody-producing B cells. Other immune cell products such as cytokines and metalloprotea ...
... and macrophages to phagocytize invading organisms is another type of defense. Cellmediated responses of the T cells and natural killer (NK) cells play a crucial role in controlling invading organisms as do the antibody-producing B cells. Other immune cell products such as cytokines and metalloprotea ...
Author`s personal copy
... with 384 selected genes. The technique was validated both at the population and single cell levels at different stages of the responses, showing 2-microglobulin to be a more stably expressed reference mRNA than either -actin or 18S RNA. SalOVA was then shown selectively to induce the OVA-specific C ...
... with 384 selected genes. The technique was validated both at the population and single cell levels at different stages of the responses, showing 2-microglobulin to be a more stably expressed reference mRNA than either -actin or 18S RNA. SalOVA was then shown selectively to induce the OVA-specific C ...
Pertussis is a highly contagious infectious disease of the respiratory
... was to identify the location of (protective) epitopes to which human Abs are directed, and to investigate the role of variation in P.69 Prn and the implications for the anti-P.69 Prn Ab response. Our results clearly indicate that Prn has evolved several ways to escape antibody and possibly phage bin ...
... was to identify the location of (protective) epitopes to which human Abs are directed, and to investigate the role of variation in P.69 Prn and the implications for the anti-P.69 Prn Ab response. Our results clearly indicate that Prn has evolved several ways to escape antibody and possibly phage bin ...
Different Nuclear Signals Are Activated by the B Cell
... mice where HEL is chronically encountered as a selfantigen, antigen binding no longer triggers CD86 expression, mitogenesis, or the capacity to resist Fasmediated apoptosis (Cooke et al., 1994; Cyster and Goodnow, 1995a; Rathmell et al., 1996). While the loss of these positive responses is consisten ...
... mice where HEL is chronically encountered as a selfantigen, antigen binding no longer triggers CD86 expression, mitogenesis, or the capacity to resist Fasmediated apoptosis (Cooke et al., 1994; Cyster and Goodnow, 1995a; Rathmell et al., 1996). While the loss of these positive responses is consisten ...
MECHANISMS OF IMMUNE RESPONSES IN CNIDARIANS
... functional information that can confirm their actual role in those processes. The TLR signaling pathway is well conserved in metazoans, and in the cnidarians H. magnipapillata, N. vectensis and A. millepora, genes encoding the universal adaptor protein MyD88, and kinases that participate in the sign ...
... functional information that can confirm their actual role in those processes. The TLR signaling pathway is well conserved in metazoans, and in the cnidarians H. magnipapillata, N. vectensis and A. millepora, genes encoding the universal adaptor protein MyD88, and kinases that participate in the sign ...
Immunological aspects of age-related diseases
... bound to multimers of CMV or EBV peptide and MHC class Ι[43]. These results mean that some population of CD8 T ...
... bound to multimers of CMV or EBV peptide and MHC class Ι[43]. These results mean that some population of CD8 T ...
The sympathetic nervous response in inflammation
... only α-ARs are activated. In the case of innate immune cells, like macrophages, this directly translates into anti-inflammatory (for example, increases in interleukin (IL)-10 via β-AR) or proinflammatory activity (for example, increases in tumor necrosis factor (TNF) via α-AR). Therefore, the simult ...
... only α-ARs are activated. In the case of innate immune cells, like macrophages, this directly translates into anti-inflammatory (for example, increases in interleukin (IL)-10 via β-AR) or proinflammatory activity (for example, increases in tumor necrosis factor (TNF) via α-AR). Therefore, the simult ...
Innate lymphoid cells - Utrecht University Repository
... to the tissue site1;30. Eosinophils are also recruited to the tissue site by eotaxin, whose expression is increased by IL-1331. Eosinophils at the tissue site proliferate upon stimulation with IL-51. They express Fc receptors for IgE and IgG and binding of IgE or IgG causes degranulation of eosinoph ...
... to the tissue site1;30. Eosinophils are also recruited to the tissue site by eotaxin, whose expression is increased by IL-1331. Eosinophils at the tissue site proliferate upon stimulation with IL-51. They express Fc receptors for IgE and IgG and binding of IgE or IgG causes degranulation of eosinoph ...
Innate and adaptive immune responses in the lungs
... IFN-γ (which can activate macrophages to destroy the intracellular bacteria) and other cytokines and chemokines produced by CD4+ T cells are critical in the host is response to Mtb. The infected DC are observed as the primary APC responsible for activating CD4+ T cells as part of the adaptive immune ...
... IFN-γ (which can activate macrophages to destroy the intracellular bacteria) and other cytokines and chemokines produced by CD4+ T cells are critical in the host is response to Mtb. The infected DC are observed as the primary APC responsible for activating CD4+ T cells as part of the adaptive immune ...
CD1 and lipid antigens
... Antigen presentation is the way in which cells present fragments of pathogens to T cells. The most well-known antigen-presenting proteins are the MHC molecules. T cell recognition of peptide fragments bound to MHC class I and II molecules is critical for effective adaptive immunity. During the past ...
... Antigen presentation is the way in which cells present fragments of pathogens to T cells. The most well-known antigen-presenting proteins are the MHC molecules. T cell recognition of peptide fragments bound to MHC class I and II molecules is critical for effective adaptive immunity. During the past ...
poster template - Argos Therapeutics
... AGS-003, an autologous dendritic cell (DC) immunotherapy has recently been evaluated in combination with sunitinib in AGS-003-006, an open label phase 2 trial for treatment of patients with newly diagnosed, unfavorable-risk, metastatic renal cell carcinoma (mRCC). The mechanism of action (MOA) of AG ...
... AGS-003, an autologous dendritic cell (DC) immunotherapy has recently been evaluated in combination with sunitinib in AGS-003-006, an open label phase 2 trial for treatment of patients with newly diagnosed, unfavorable-risk, metastatic renal cell carcinoma (mRCC). The mechanism of action (MOA) of AG ...
Genetically Engineered Probiotics
... infected children. They also can have long-term effects on educational achievement and productivity [4]. The only drugs available to treat hookworms in humans were originally developed to combat parasites that infect farm animals. They were only partially effective against the range of intestinal pa ...
... infected children. They also can have long-term effects on educational achievement and productivity [4]. The only drugs available to treat hookworms in humans were originally developed to combat parasites that infect farm animals. They were only partially effective against the range of intestinal pa ...
The properties and functions of effector T cells
... Killing of target cells by CD8+ cytotoxic T cells Cytotoxic T cells kill their target cells by inducing them to undergo apoptosis. Cells dying by apoptosis are not lysed or disintegrated, unlike cells undergoing necrosis. This prevents the release of intact pathogens from dead cells and thus infecti ...
... Killing of target cells by CD8+ cytotoxic T cells Cytotoxic T cells kill their target cells by inducing them to undergo apoptosis. Cells dying by apoptosis are not lysed or disintegrated, unlike cells undergoing necrosis. This prevents the release of intact pathogens from dead cells and thus infecti ...
Cells - Home
... signal, which is antigen-specific, is provided through the T cell receptor which interacts with peptide-MHC molecules on the membrane of antigen presenting cells (APC). A second signal, the co-stimulatory signal, is antigen nonspecific and is provided by the interaction between co-stimulatory molecu ...
... signal, which is antigen-specific, is provided through the T cell receptor which interacts with peptide-MHC molecules on the membrane of antigen presenting cells (APC). A second signal, the co-stimulatory signal, is antigen nonspecific and is provided by the interaction between co-stimulatory molecu ...
HIV and Malnutrition: Effects on Immune System
... Clinical and Developmental Immunology some of these monkeys, when the CD8+ T cells regenerated, the control of viral replication was regained [10]. Humoral immunity to HIV is expressed by neutralising antibodies. Anti-HIV antibodies are able to bind cell-free virus and potentially prevent establishe ...
... Clinical and Developmental Immunology some of these monkeys, when the CD8+ T cells regenerated, the control of viral replication was regained [10]. Humoral immunity to HIV is expressed by neutralising antibodies. Anti-HIV antibodies are able to bind cell-free virus and potentially prevent establishe ...
Immune system
The immune system is a system of many biological structures and processes within an organism that protects against disease. To function properly, an immune system must detect a wide variety of agents, known as pathogens, from viruses to parasitic worms, and distinguish them from the organism's own healthy tissue. In many species, the immune system can be classified into subsystems, such as the innate immune system versus the adaptive immune system, or humoral immunity versus cell-mediated immunity.Pathogens can rapidly evolve and adapt, and thereby avoid detection and neutralization by the immune system; however, multiple defense mechanisms have also evolved to recognize and neutralize pathogens. Even simple unicellular organisms such as bacteria possess a rudimentary immune system, in the form of enzymes that protect against bacteriophage infections. Other basic immune mechanisms evolved in ancient eukaryotes and remain in their modern descendants, such as plants and insects. These mechanisms include phagocytosis, antimicrobial peptides called defensins, and the complement system. Jawed vertebrates, including humans, have even more sophisticated defense mechanisms, including the ability to adapt over time to recognize specific pathogens more efficiently. Adaptive (or acquired) immunity creates immunological memory after an initial response to a specific pathogen, leading to an enhanced response to subsequent encounters with that same pathogen. This process of acquired immunity is the basis of vaccination.Disorders of the immune system can result in autoimmune diseases, inflammatory diseases and cancer.Immunodeficiency occurs when the immune system is less active than normal, resulting in recurring and life-threatening infections. In humans, immunodeficiency can either be the result of a genetic disease such as severe combined immunodeficiency, acquired conditions such as HIV/AIDS, or the use of immunosuppressive medication. In contrast, autoimmunity results from a hyperactive immune system attacking normal tissues as if they were foreign organisms. Common autoimmune diseases include Hashimoto's thyroiditis, rheumatoid arthritis, diabetes mellitus type 1, and systemic lupus erythematosus. Immunology covers the study of all aspects of the immune system.