Immune Response – Overview
... bind that specific antigen and immobilize it, preventing it from causing infection. Antibodies are specific for only one antigen. B cells must interact with Helper T cells, other specialized white blood cells, to initiate antibody production. An important concept is that once activated, memory cells ...
... bind that specific antigen and immobilize it, preventing it from causing infection. Antibodies are specific for only one antigen. B cells must interact with Helper T cells, other specialized white blood cells, to initiate antibody production. An important concept is that once activated, memory cells ...
Molecularly defined vaccines and clinical immunotherapies
... Choice of antigens for cancer vaccines Targeting of multiple tumor-antigens, restricted by different HLA-A,-B,-C (class I) alleles, and different HLA-DR,-DQ,-DP (class II) alleles Shared antigens, and/or mutated antigens Model antigen(s): to assess the immune response (biological readout) to induce ...
... Choice of antigens for cancer vaccines Targeting of multiple tumor-antigens, restricted by different HLA-A,-B,-C (class I) alleles, and different HLA-DR,-DQ,-DP (class II) alleles Shared antigens, and/or mutated antigens Model antigen(s): to assess the immune response (biological readout) to induce ...
Immunity Textbook
... Interferons are cytokines that bind to cells causing them to produce substances that inhibit viral replication. One type of interferon can affect many types of viruses. Interferons can also activate other immune cells such as macrophages and natural killer cells. Some cytokines produce fever. Interl ...
... Interferons are cytokines that bind to cells causing them to produce substances that inhibit viral replication. One type of interferon can affect many types of viruses. Interferons can also activate other immune cells such as macrophages and natural killer cells. Some cytokines produce fever. Interl ...
LACZIK_Pharmacology - 3.practice
... More than 500 microbial species live in a healthy adult gut, adding two pounds to its weight There are 1012 bacteria/g in the gut There are 100-times more bacterial genes than eukaryotic genes They produce a significant portion of vitamin K1 ...
... More than 500 microbial species live in a healthy adult gut, adding two pounds to its weight There are 1012 bacteria/g in the gut There are 100-times more bacterial genes than eukaryotic genes They produce a significant portion of vitamin K1 ...
NK receptors
... - Specific antigen/MHC class I recognition by TCR on CTL, or engagement of the NK’s natural cytotoxic receptors (NCR) (green) by non-MHC ligands (orange) on the surface of the target cell. This results in a polarization of the cell: the actin cytoskeleton (green staining in the immunofluorescence mi ...
... - Specific antigen/MHC class I recognition by TCR on CTL, or engagement of the NK’s natural cytotoxic receptors (NCR) (green) by non-MHC ligands (orange) on the surface of the target cell. This results in a polarization of the cell: the actin cytoskeleton (green staining in the immunofluorescence mi ...
Post streptococcal glomerulonephritis (PSGN)
... Two “nephritogenic” proteins have thus far been identified in Streptococcal infections and include SpeB, a bacterial serine protease enzyme, and NAPIr, a secreted bacterial protein known as “nephritis-associated plasmin receptor”. It is thought that these proteins when present in the kidney precipita ...
... Two “nephritogenic” proteins have thus far been identified in Streptococcal infections and include SpeB, a bacterial serine protease enzyme, and NAPIr, a secreted bacterial protein known as “nephritis-associated plasmin receptor”. It is thought that these proteins when present in the kidney precipita ...
Lymphatic System
... soldiers, destroying the invaders that the intelligence system has identified (hand to hand combat) Signal other cells if needed for additional help ...
... soldiers, destroying the invaders that the intelligence system has identified (hand to hand combat) Signal other cells if needed for additional help ...
T Cells - GEOCITIES.ws
... Cytotoxic T cells=Killer T cells Activated by cytokines from helper T cells Start proliferating Recognize antigens presented by MHC class I – All cells in body have class I MHC – Recognizes cells in body that are infected with viruses ...
... Cytotoxic T cells=Killer T cells Activated by cytokines from helper T cells Start proliferating Recognize antigens presented by MHC class I – All cells in body have class I MHC – Recognizes cells in body that are infected with viruses ...
Presentation
... responses to gut commensals?) – Viral hepatitis (CTLs kill virus-infected hepatocytes); not considered an example of “hypersensitivity” ...
... responses to gut commensals?) – Viral hepatitis (CTLs kill virus-infected hepatocytes); not considered an example of “hypersensitivity” ...
Document
... functions related to immune defense 4. Immune clearance. Removes immune complexes from the circulation and deposits them in the liver where they are degraded. C3b facilitates immune complex binding to CR1 on RBCs. In the liver and spleen the complexes are stripped from the RBC and phagocytosed. Comp ...
... functions related to immune defense 4. Immune clearance. Removes immune complexes from the circulation and deposits them in the liver where they are degraded. C3b facilitates immune complex binding to CR1 on RBCs. In the liver and spleen the complexes are stripped from the RBC and phagocytosed. Comp ...
organization of the immune system
... •Up to puberty/adolescence the size of the thymus is increasing and naive T lymphocytes are produced in waves to ensure protective immune responses •A sustained loss of tissue mass, cellularity and functionality of the thymus starts after puberty and lasts to middle age followed by a slower rate of ...
... •Up to puberty/adolescence the size of the thymus is increasing and naive T lymphocytes are produced in waves to ensure protective immune responses •A sustained loss of tissue mass, cellularity and functionality of the thymus starts after puberty and lasts to middle age followed by a slower rate of ...
No Slide Title - University of Colorado
... facilitate effective repair and regeneration of defective tissues. ...
... facilitate effective repair and regeneration of defective tissues. ...
The First and Second Lines of Defense Against Disease
... Chronic Inflammation: this is long term and can last for months or even years ...
... Chronic Inflammation: this is long term and can last for months or even years ...
Living systems are open system organized in a hierarchical manner
... Among the diversity of immune cell types, dendritic cells (DCs) are central to the immune response and have the unique capacity to link innate and adaptive immunity. Their function is tightly linked to their ability to integrate multiple signals from a complex inflammatory environment and to translat ...
... Among the diversity of immune cell types, dendritic cells (DCs) are central to the immune response and have the unique capacity to link innate and adaptive immunity. Their function is tightly linked to their ability to integrate multiple signals from a complex inflammatory environment and to translat ...
emotions - Psychology
... Elements of the Immune System Leukocytes (White blood cells) Most important elements Patrol the blood & fluids Antigens: Intruders have different surface proteins (nonself) than our own (self) WBCs attack antigens Macrophages and B Cells are specific defenses Antibodies search for specific antigens ...
... Elements of the Immune System Leukocytes (White blood cells) Most important elements Patrol the blood & fluids Antigens: Intruders have different surface proteins (nonself) than our own (self) WBCs attack antigens Macrophages and B Cells are specific defenses Antibodies search for specific antigens ...
chapter 14-disease - Woodland Christian School
... infectious disease a disease that is contagious and is caused by a pathogen lymphatic system part of the immune system and helps fight pathogens Three ways that infectious and noninfectious diseases are alike are both are abnormal conditions causing illness, both produce symptoms , and both can be e ...
... infectious disease a disease that is contagious and is caused by a pathogen lymphatic system part of the immune system and helps fight pathogens Three ways that infectious and noninfectious diseases are alike are both are abnormal conditions causing illness, both produce symptoms , and both can be e ...
Exporter la page en pdf
... Innate immune responses are considered the first defensive line against harmful conditions, including cancer. Human dendritic cells play a key role in the control of these responses and are a promising constituent of rational immune therapies. Indeed, dendritic cells possess a unique machinery to det ...
... Innate immune responses are considered the first defensive line against harmful conditions, including cancer. Human dendritic cells play a key role in the control of these responses and are a promising constituent of rational immune therapies. Indeed, dendritic cells possess a unique machinery to det ...
White Blood Cells (leukocytes)
... Blood contains three types of lymphocytes: A- B cells: B- cells produce antibodies that are associated with pathogens for destruction. In addition to linking function after an attack to cause disease, some B cells become capable of producing antibodies specific for the pathogen to serve as a memory ...
... Blood contains three types of lymphocytes: A- B cells: B- cells produce antibodies that are associated with pathogens for destruction. In addition to linking function after an attack to cause disease, some B cells become capable of producing antibodies specific for the pathogen to serve as a memory ...
Genetic engineering to protect against virus infection
... communication during an antiviral defense. • Their presence is one of the first indicators that the host has been infected. • They act locally, near the cells that make them. • They control inflammation, induce and antiviral state in cells and regulate the adaptive immune response. • They exert thei ...
... communication during an antiviral defense. • Their presence is one of the first indicators that the host has been infected. • They act locally, near the cells that make them. • They control inflammation, induce and antiviral state in cells and regulate the adaptive immune response. • They exert thei ...
Immune system
The immune system is a system of many biological structures and processes within an organism that protects against disease. To function properly, an immune system must detect a wide variety of agents, known as pathogens, from viruses to parasitic worms, and distinguish them from the organism's own healthy tissue. In many species, the immune system can be classified into subsystems, such as the innate immune system versus the adaptive immune system, or humoral immunity versus cell-mediated immunity.Pathogens can rapidly evolve and adapt, and thereby avoid detection and neutralization by the immune system; however, multiple defense mechanisms have also evolved to recognize and neutralize pathogens. Even simple unicellular organisms such as bacteria possess a rudimentary immune system, in the form of enzymes that protect against bacteriophage infections. Other basic immune mechanisms evolved in ancient eukaryotes and remain in their modern descendants, such as plants and insects. These mechanisms include phagocytosis, antimicrobial peptides called defensins, and the complement system. Jawed vertebrates, including humans, have even more sophisticated defense mechanisms, including the ability to adapt over time to recognize specific pathogens more efficiently. Adaptive (or acquired) immunity creates immunological memory after an initial response to a specific pathogen, leading to an enhanced response to subsequent encounters with that same pathogen. This process of acquired immunity is the basis of vaccination.Disorders of the immune system can result in autoimmune diseases, inflammatory diseases and cancer.Immunodeficiency occurs when the immune system is less active than normal, resulting in recurring and life-threatening infections. In humans, immunodeficiency can either be the result of a genetic disease such as severe combined immunodeficiency, acquired conditions such as HIV/AIDS, or the use of immunosuppressive medication. In contrast, autoimmunity results from a hyperactive immune system attacking normal tissues as if they were foreign organisms. Common autoimmune diseases include Hashimoto's thyroiditis, rheumatoid arthritis, diabetes mellitus type 1, and systemic lupus erythematosus. Immunology covers the study of all aspects of the immune system.