slides#5 - DENTISTRY 2012
... Overview of the stages of lymphocyte development and function Antigen Indpendeny Development ...
... Overview of the stages of lymphocyte development and function Antigen Indpendeny Development ...
Transplantation Immunology
... keep our body tumor-free. Both innate immunity and acquired immunity participate in this process which has been extensively investigated for potential approaches to manipulate. Tumor Immunology -Outlines • Tumor surveillance: the same machinery against virally infected cells is used • Tumor antigen: ...
... keep our body tumor-free. Both innate immunity and acquired immunity participate in this process which has been extensively investigated for potential approaches to manipulate. Tumor Immunology -Outlines • Tumor surveillance: the same machinery against virally infected cells is used • Tumor antigen: ...
What is the purpose of a immune system?
... attack pathogens, but don’t “remember” for next time leukocytes phagocytic white blood cells macrophages, neutrophils, natural killer cells ...
... attack pathogens, but don’t “remember” for next time leukocytes phagocytic white blood cells macrophages, neutrophils, natural killer cells ...
What is the purpose of a immune system?
... attack pathogens, but don’t “remember” for next time leukocytes phagocytic white blood cells macrophages, neutrophils, natural killer cells ...
... attack pathogens, but don’t “remember” for next time leukocytes phagocytic white blood cells macrophages, neutrophils, natural killer cells ...
Innate Immune Response - Morgan Community College
... Antimicrobial peptides inserted into microbial membrane Found on mucous membranes and in phagocytes ...
... Antimicrobial peptides inserted into microbial membrane Found on mucous membranes and in phagocytes ...
Who Gets Lupus?
... C1q deficiency (rare, but greatest risk!!) Chromosome 1 region 1q41-43 (PARP) region 1q23 (FcRIIA, RIIIA) Polymorphisms in IL-10, IL-6 and mannose-binding protein ...
... C1q deficiency (rare, but greatest risk!!) Chromosome 1 region 1q41-43 (PARP) region 1q23 (FcRIIA, RIIIA) Polymorphisms in IL-10, IL-6 and mannose-binding protein ...
Exporter la page en pdf
... critical for IFN and inflammatory gene expression during innate immune responses. However, the role of STING in adaptive immunity is still unknown. In this study, we show that STING activation reduces the proliferation of T lymphocytes. This activity was independent of TBK1 and IRF3 recruitment and o ...
... critical for IFN and inflammatory gene expression during innate immune responses. However, the role of STING in adaptive immunity is still unknown. In this study, we show that STING activation reduces the proliferation of T lymphocytes. This activity was independent of TBK1 and IRF3 recruitment and o ...
Tracking movement of immune cells identifies key first steps in
... autoimmune diseases of the joints - including rheumatoid arthritis and lupus - and in many cases is caused by a type of inflammation called type III hypersensitivity. That reaction results when a localized accumulation of immune complexes antibodies bound to their antigens - is deposited in tissue a ...
... autoimmune diseases of the joints - including rheumatoid arthritis and lupus - and in many cases is caused by a type of inflammation called type III hypersensitivity. That reaction results when a localized accumulation of immune complexes antibodies bound to their antigens - is deposited in tissue a ...
Health, Gnotobiology and Infectious Diseases
... – Levels increase during parasitic infections and other allergic reactions – Attaches to mast cells and basophils which release chemicals like histamine that produce inflammation and cause tissue damage – Over response with IgE associated with hypersensitivity reactions such as hay fever, food and s ...
... – Levels increase during parasitic infections and other allergic reactions – Attaches to mast cells and basophils which release chemicals like histamine that produce inflammation and cause tissue damage – Over response with IgE associated with hypersensitivity reactions such as hay fever, food and s ...
Lymphatic System and Immunity
... Plasma Cells • Produce huge numbers of antibodies – 2000/second ...
... Plasma Cells • Produce huge numbers of antibodies – 2000/second ...
Antibodies
... 2. Macrophages engulf the microbes by phagocytosis • Digested microbes enter the lymph and are destroyed. • Ab can cause microbes to clump making them ...
... 2. Macrophages engulf the microbes by phagocytosis • Digested microbes enter the lymph and are destroyed. • Ab can cause microbes to clump making them ...
The Immune System
... “Hidden” antigens or “new self-antigens” caused by mutation or damage to cell Reaction of antibodies produced against foreign antigens with self-antigens (Strep antibodies can react with heart antigens and cause rheumatic fever) ...
... “Hidden” antigens or “new self-antigens” caused by mutation or damage to cell Reaction of antibodies produced against foreign antigens with self-antigens (Strep antibodies can react with heart antigens and cause rheumatic fever) ...
... trial was conducted to enroll patients with Stage IIIB/IV NSCLC. Sixteen patients received 2 vaccinations at a dose of Ad-CCL21-DC (A, B, C, or D; 1 × 106, 5 × 106, 1 × 107, or 3 × 107 cells/injection) by IT injection (days 0 and 7). Peripheral blood was collected for antigen-specific ELISPOT assays ...
Specific Immunity - Truro School Moodle
... Memory Cells • Live longer than plasma cells – often for decades. • They do not directly produce antibodies but circulate in the plama and tissue fluid. • When they encounter the same antigen later they can divide rapidly and clone to produce more plasma and memory cells. • Plasma cells then produc ...
... Memory Cells • Live longer than plasma cells – often for decades. • They do not directly produce antibodies but circulate in the plama and tissue fluid. • When they encounter the same antigen later they can divide rapidly and clone to produce more plasma and memory cells. • Plasma cells then produc ...
Ch 6 Med Term and Ch 15 BS Lymphatic_ImmuneSystems
... body regards as foreign – Stimulates immune response ...
... body regards as foreign – Stimulates immune response ...
Chapter 9 Immunity and the Lymphatic System Our body`s innate
... o The individual’s body makes antibodies against a particular antigen o This can happen through natural infection or through immunization using vaccines o The primary response is slower and shorter-lived while the secondary exposure is a rapid, strong response o This type of immunity is usually long ...
... o The individual’s body makes antibodies against a particular antigen o This can happen through natural infection or through immunization using vaccines o The primary response is slower and shorter-lived while the secondary exposure is a rapid, strong response o This type of immunity is usually long ...
Tissue effector memory T cells Lymphoid central memory T cells
... The number of memory T-cells also stays constant over decades ...
... The number of memory T-cells also stays constant over decades ...
4c * Adaptive Immunity
... perforin (protein) makes a pore in membrane ions and water enters pores infected cell lyses Remember, involved with “self” ...
... perforin (protein) makes a pore in membrane ions and water enters pores infected cell lyses Remember, involved with “self” ...
Antibody production
... tissues and are activated to perform their effector functions They secrete cytokines that activate macrophages and help B cells The activation of T cells requires: Recognition of peptide –MHC complex ...
... tissues and are activated to perform their effector functions They secrete cytokines that activate macrophages and help B cells The activation of T cells requires: Recognition of peptide –MHC complex ...
Immune
... – Bind to common antigens on many bacteria and plant proteins – Abundant in intestines and respiratory tract to keep out particles ...
... – Bind to common antigens on many bacteria and plant proteins – Abundant in intestines and respiratory tract to keep out particles ...
Immune system
The immune system is a system of many biological structures and processes within an organism that protects against disease. To function properly, an immune system must detect a wide variety of agents, known as pathogens, from viruses to parasitic worms, and distinguish them from the organism's own healthy tissue. In many species, the immune system can be classified into subsystems, such as the innate immune system versus the adaptive immune system, or humoral immunity versus cell-mediated immunity.Pathogens can rapidly evolve and adapt, and thereby avoid detection and neutralization by the immune system; however, multiple defense mechanisms have also evolved to recognize and neutralize pathogens. Even simple unicellular organisms such as bacteria possess a rudimentary immune system, in the form of enzymes that protect against bacteriophage infections. Other basic immune mechanisms evolved in ancient eukaryotes and remain in their modern descendants, such as plants and insects. These mechanisms include phagocytosis, antimicrobial peptides called defensins, and the complement system. Jawed vertebrates, including humans, have even more sophisticated defense mechanisms, including the ability to adapt over time to recognize specific pathogens more efficiently. Adaptive (or acquired) immunity creates immunological memory after an initial response to a specific pathogen, leading to an enhanced response to subsequent encounters with that same pathogen. This process of acquired immunity is the basis of vaccination.Disorders of the immune system can result in autoimmune diseases, inflammatory diseases and cancer.Immunodeficiency occurs when the immune system is less active than normal, resulting in recurring and life-threatening infections. In humans, immunodeficiency can either be the result of a genetic disease such as severe combined immunodeficiency, acquired conditions such as HIV/AIDS, or the use of immunosuppressive medication. In contrast, autoimmunity results from a hyperactive immune system attacking normal tissues as if they were foreign organisms. Common autoimmune diseases include Hashimoto's thyroiditis, rheumatoid arthritis, diabetes mellitus type 1, and systemic lupus erythematosus. Immunology covers the study of all aspects of the immune system.