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Kevin Ahern's Biochemistry Course (BB 350) at Oregon State University
Kevin Ahern's Biochemistry Course (BB 350) at Oregon State University

... Highlights Immune System 1. The immune system contains the innate immunity system and the adaptive immunity system. 2. The innate system uses receptors that bind to common lipopolysaccharide structures on the surface of Gram negative bacteria. 3. The adaptive immune system system contains two major ...
The Guardian at the Gate - Quintessential Health Care
The Guardian at the Gate - Quintessential Health Care

... • The lymph flows from the interstitial fluid through lymphatic vessels up to either the thoracic duct or right lymph duct, which terminate in the subclavian veins, where lymph is mixed into the blood. (The right lymph duct drains the right sides of the thorax, neck, and head, whereas the thoracic d ...
1. dia - immunology.unideb.hu
1. dia - immunology.unideb.hu

... cells proliferate. The surrounding stromal cells (fibroblasts) also proliferate. Both cells increase their production of TGF-β. This TGF-β acts on the surrounding stromal cells, immune cells, endothelial and smooth-muscle cells. It causes immunosuppression and angiogenesis, which makes the cancer mo ...
Nature Immunology: Changes to mitochondrial metabolism allow the
Nature Immunology: Changes to mitochondrial metabolism allow the

... The immune system is equipped with the mechanisms to adapt to bacterial infection, and one of the keys to this efficient reaction is rooted in changes that take place in the metabolism of mitochondria. These changes are important for adaptation of the response of immune cells to live or dead bacteri ...
Innate lymphocytes_LÁ_optional
Innate lymphocytes_LÁ_optional

... promyeloytic leukemia zincfinger protein • Selected on double-positive cells in the thymus • Lipid antigens are presened by CD1d • CD1d is constrantly recycling between the membrane and the endosomal vesicles • Saponins allow removal of self-lypids and loading of foreign lipids ...
Slayt 1
Slayt 1

... by bacterial surfaces • Classic pathway activated later by antibody-antigen complexes • Production of chemotactic and anaphylotoxic proteins (C3a, C5a) • Opsonization of bacteria (C3b) • Promotion of killing of gram-negative bacteria • Activation of B cells (C3d) ...
RFC_CP_Decouverte_immunologie_CIML
RFC_CP_Decouverte_immunologie_CIML

... “This is the first time that redundancy between these 2 cell populations has been formally demonstrated,” says Éric Vivier. “All the evidence suggests that these two defence systems were co-selected during evolution to ensure optimal protection against infection.” Ultimately, this discovery could th ...
auto- immune hemolytic anaemia
auto- immune hemolytic anaemia

Specific Resistance = Immunity
Specific Resistance = Immunity

... Antigen = a substance with unique 3D form that causes antibody formation in B cells (lymphocytes). Antigens may possess one or more types of reactive molecular components, called antigenic determinants or epitopes. Antigen binding sites on the antibody Fab fragments specifically recognize and chemic ...
Surname 1 Name Instructor Course Date Human Immune System
Surname 1 Name Instructor Course Date Human Immune System

... acts as a mechanical barrier to entry of pathogens. The body of the human being cannot be entirely physical sealed against the disease causing organisms. Other systems are therefore present to protect the body openings including lungs genitourinary tract and intestines. Lungs get protection from fac ...
PowerPoint 簡報
PowerPoint 簡報

... Leukocyte Activation and Migration ...
BIOL212ImmuneSystemNotes
BIOL212ImmuneSystemNotes

... The helper T cell is activated, proliferates, and forms a clone of helper T cells, which then activate the appropriate B cells Cytotoxic T cells are the effector cells in the cell-mediated immune response Cytotoxic T cells recognize fragments of foreign proteins produced by infected cells and posses ...
lac-1
lac-1

... The Immune System Includes Innate and Adaptive Components Immunity—the state of protection from infectious disease has both a less specific and more specific component. The less specific component, innate immunity, provides the first line of defense against infection.Most components of innate immuni ...
Packet 14- Acquired Immunity
Packet 14- Acquired Immunity

Diapositiva 1
Diapositiva 1

... A comparison of the integration site in transduced T cells before and after infusion showed that vector integration within genes involved in cell cycle control or in other physiological T cellfunctions were counter-selected in vivo. Furthermore, no clonal selection or expansion could be observed dur ...
Course of Immunology
Course of Immunology

Feel Your Best with the BOOM!
Feel Your Best with the BOOM!

Chapter 8 Immune Organs
Chapter 8 Immune Organs

... The skin contains a specialized cutaneous immune system consisting of lymphocytes and APCs (such as Langerhan’s cell) ...
Taxonomy and Systematics: Seeking Order Amidst Diversity
Taxonomy and Systematics: Seeking Order Amidst Diversity

... Skin is an inhospitable barrier of dead, dry cells, & secretions containing oil & lactic acid Mucous membranes in respiratory, digestive & urogenital tracts secrete mucus & antibiotic chemicals (e.g., lysozyme, which digests bacterial cell walls) If external defenses are not effective – nonspecific, ...
Topic 6.3 Defence against infectious disease
Topic 6.3 Defence against infectious disease

... Phagocytes are found in the blood and in body tissues such as the lungs. After phagocytes engulf pathogens, they destroy them with digestive enzymes found in lysosomes. ...
Introduction to Immunology and Immunotoxicology
Introduction to Immunology and Immunotoxicology

... Recognition and elimination of pathogenic organisms ...
Immunology --- prevention and treatment of infectious diseases
Immunology --- prevention and treatment of infectious diseases

... Activation of dendritic cells ...
STUDY GUIDE - SCF Faculty Site Homepage
STUDY GUIDE - SCF Faculty Site Homepage

acquired immunity
acquired immunity

... One naïve T- cell ( in thousands ) is likely to be ( specific for a particular antigen ) and will be trapped in the the L.node . ...
ORGANIZATION OF THE IMMUNE SYSTEM
ORGANIZATION OF THE IMMUNE SYSTEM

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Immune system



The immune system is a system of many biological structures and processes within an organism that protects against disease. To function properly, an immune system must detect a wide variety of agents, known as pathogens, from viruses to parasitic worms, and distinguish them from the organism's own healthy tissue. In many species, the immune system can be classified into subsystems, such as the innate immune system versus the adaptive immune system, or humoral immunity versus cell-mediated immunity.Pathogens can rapidly evolve and adapt, and thereby avoid detection and neutralization by the immune system; however, multiple defense mechanisms have also evolved to recognize and neutralize pathogens. Even simple unicellular organisms such as bacteria possess a rudimentary immune system, in the form of enzymes that protect against bacteriophage infections. Other basic immune mechanisms evolved in ancient eukaryotes and remain in their modern descendants, such as plants and insects. These mechanisms include phagocytosis, antimicrobial peptides called defensins, and the complement system. Jawed vertebrates, including humans, have even more sophisticated defense mechanisms, including the ability to adapt over time to recognize specific pathogens more efficiently. Adaptive (or acquired) immunity creates immunological memory after an initial response to a specific pathogen, leading to an enhanced response to subsequent encounters with that same pathogen. This process of acquired immunity is the basis of vaccination.Disorders of the immune system can result in autoimmune diseases, inflammatory diseases and cancer.Immunodeficiency occurs when the immune system is less active than normal, resulting in recurring and life-threatening infections. In humans, immunodeficiency can either be the result of a genetic disease such as severe combined immunodeficiency, acquired conditions such as HIV/AIDS, or the use of immunosuppressive medication. In contrast, autoimmunity results from a hyperactive immune system attacking normal tissues as if they were foreign organisms. Common autoimmune diseases include Hashimoto's thyroiditis, rheumatoid arthritis, diabetes mellitus type 1, and systemic lupus erythematosus. Immunology covers the study of all aspects of the immune system.
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