Cenchao Shen - RMIT Research Repository
... I certify that except where due acknowledgement has been made, the work is that of the author alone; the work has not been submitted previously, in whole or in part, to qualify for any other academic award; the content of the thesis is the result of work which has been carried out since the official ...
... I certify that except where due acknowledgement has been made, the work is that of the author alone; the work has not been submitted previously, in whole or in part, to qualify for any other academic award; the content of the thesis is the result of work which has been carried out since the official ...
Two Distinct Mechanisms for Induction of Dendritic Cell Apoptosis in
... a relative resistance to the experimental infection (14). Macrophage intracellular killing of opsonized Streptococcus pneumoniae has been associated with the induction of a caspase-dependent but Fas-independent apoptosis (11). However, S. pneumoniae pneumolysin, which induces NO production in macrop ...
... a relative resistance to the experimental infection (14). Macrophage intracellular killing of opsonized Streptococcus pneumoniae has been associated with the induction of a caspase-dependent but Fas-independent apoptosis (11). However, S. pneumoniae pneumolysin, which induces NO production in macrop ...
Immunological and Genetic Aspects of Narcolepsy
... DQB1*06:02 effects. The genes encoding DQB1 and DQA1 (encoding DQβ and DQα, respectively) are located adjacent to each other within a 20 kb segment of the Major Histocompatibility Complex (MHC) class II region on human chromosome.6 The protein products form a αβ heterodimer known as the HLA DQ antig ...
... DQB1*06:02 effects. The genes encoding DQB1 and DQA1 (encoding DQβ and DQα, respectively) are located adjacent to each other within a 20 kb segment of the Major Histocompatibility Complex (MHC) class II region on human chromosome.6 The protein products form a αβ heterodimer known as the HLA DQ antig ...
Bio 1305--Modern Concepts of Bioscience
... 9. Distinguish between saturated and unsaturated fat and list some unique emergent properties that are a consequence of these structural differences 10. Describe the characteristics that distinguish proteins from the major classes of macromolecules, and explain the biologically important functions o ...
... 9. Distinguish between saturated and unsaturated fat and list some unique emergent properties that are a consequence of these structural differences 10. Describe the characteristics that distinguish proteins from the major classes of macromolecules, and explain the biologically important functions o ...
TUMOR NECROSIS FACTOR ALPHA (TNF-a)
... superfamily, TNFR1 and TNFR2. TNFR1 is constitutively expressed by most cell types, whereas TNFR2 has a highly regulated pattern of cellular expression. Binding of TNF to TNFR1 mediates the translocation of TNFR1 to lipid rafts, where it recruits the adaptor protein, TNF receptor-associated death do ...
... superfamily, TNFR1 and TNFR2. TNFR1 is constitutively expressed by most cell types, whereas TNFR2 has a highly regulated pattern of cellular expression. Binding of TNF to TNFR1 mediates the translocation of TNFR1 to lipid rafts, where it recruits the adaptor protein, TNF receptor-associated death do ...
Medical Virology of Hepatitis B: how it began and where we are now
... with the viral antigen. The method most often used was the quite difficult complement fixation reaction (CFR), which was originally developed for diagnosing syphilis. In addition to the human patient serum, and the viral antigen (e.g. from infected chicken embryos or tissue cultures), one needs shee ...
... with the viral antigen. The method most often used was the quite difficult complement fixation reaction (CFR), which was originally developed for diagnosing syphilis. In addition to the human patient serum, and the viral antigen (e.g. from infected chicken embryos or tissue cultures), one needs shee ...
the effects of thymus and other lymphoid organs enclosed in
... diffusion chambers containing either neonatal or adult spleen, or an adult lymph node also accepted Ak homografts for prolonged intervals. Thus, none of these lymphoid organs favourably influenced the defective homograft immunity found in mice thymectomized soon after birth. On the other hand, the p ...
... diffusion chambers containing either neonatal or adult spleen, or an adult lymph node also accepted Ak homografts for prolonged intervals. Thus, none of these lymphoid organs favourably influenced the defective homograft immunity found in mice thymectomized soon after birth. On the other hand, the p ...
Subtype-Specific Sorting of the ETA Endothelin Receptor by a Novel
... class 1 PDZ (postsynaptic density 95/disc-large/zona occludens) domain proteins (Hall et al., 1998). The PDZ ligand of the 2-AR has been reported to bind EBP50/Na⫹/H⫹ exchange regulatory factor 1 [Ezrin-radixin-moesin (ERM)binding phosphoprotein-50] and to promote recycling of the 2-AR by linking ...
... class 1 PDZ (postsynaptic density 95/disc-large/zona occludens) domain proteins (Hall et al., 1998). The PDZ ligand of the 2-AR has been reported to bind EBP50/Na⫹/H⫹ exchange regulatory factor 1 [Ezrin-radixin-moesin (ERM)binding phosphoprotein-50] and to promote recycling of the 2-AR by linking ...
Cells Intestinal Lamina Propria as Regulatory T Cells in Human
... Isolation of LP mononuclear cells (LPMCs) from intestinal mucosa LPMCs were isolated from surgically resected intestinal specimens using enzymatic techniques as previously described (43). Briefly, the dissected mucosa was incubated in calcium and magnesium-free HBSS containing 2.5% FBS and 1 mM DTT ...
... Isolation of LP mononuclear cells (LPMCs) from intestinal mucosa LPMCs were isolated from surgically resected intestinal specimens using enzymatic techniques as previously described (43). Briefly, the dissected mucosa was incubated in calcium and magnesium-free HBSS containing 2.5% FBS and 1 mM DTT ...
709_2010_211_MOESM2_ESM - Springer Static Content Server
... pattern and is involved in vascular strand development in the leaf, control of leaf shape, size and symmetry, male gametophyte development and ovule specification and function. Anthers of double mutants (bam1bam2) appeared abnormal at a very early stage and lack the endothecium, middle, and tapetum ...
... pattern and is involved in vascular strand development in the leaf, control of leaf shape, size and symmetry, male gametophyte development and ovule specification and function. Anthers of double mutants (bam1bam2) appeared abnormal at a very early stage and lack the endothecium, middle, and tapetum ...
Biology: Concepts and Connections, 6e (Campbell)
... ATP يمكن للتفاعالت المستقبله للطاقه ان تعزز عن طريق ربط بينها وبين التحلل من الطاقة العالية ورابطة الفوسفات في ...
... ATP يمكن للتفاعالت المستقبله للطاقه ان تعزز عن طريق ربط بينها وبين التحلل من الطاقة العالية ورابطة الفوسفات في ...
Cellulose Biosynthesis Inhibitors - buleria
... Introduction....................................................................................................................... 85 Results.................................................................................................................................. 88 Discussion........ ...
... Introduction....................................................................................................................... 85 Results.................................................................................................................................. 88 Discussion........ ...
Clever tricks EBV employed to modulate innate immunity during
... and BclX. Thirdly, NFκB is involved in B-cell differentiation and survival, but also in T-cell activation. This observation together with the fact that NFκB is activated upon PRR triggering, implies a role for NFκB in linking innate and adaptive immunity. Another effect of NFκB activation is the exp ...
... and BclX. Thirdly, NFκB is involved in B-cell differentiation and survival, but also in T-cell activation. This observation together with the fact that NFκB is activated upon PRR triggering, implies a role for NFκB in linking innate and adaptive immunity. Another effect of NFκB activation is the exp ...
Cytokines from the pig conceptus: roles in conceptus development
... with cellular communication between the uterine epithelium and stroma in establishing a proper uterine environment for conceptus attachment and early development [10-12]. Progesterone’s role in opening the window for implantation during early pregnancy is associated with cell-specific changes in exp ...
... with cellular communication between the uterine epithelium and stroma in establishing a proper uterine environment for conceptus attachment and early development [10-12]. Progesterone’s role in opening the window for implantation during early pregnancy is associated with cell-specific changes in exp ...
Proceedings - Animal Nutrition Conference of Canada
... community, chose to focus on nutritional strategies to reduce the use of antimicrobials in animal production. Apart from the new legislative constraints that will force the industry to adapt and find new ways to maintain livestock profitability, there is also an opportunity for us to better understa ...
... community, chose to focus on nutritional strategies to reduce the use of antimicrobials in animal production. Apart from the new legislative constraints that will force the industry to adapt and find new ways to maintain livestock profitability, there is also an opportunity for us to better understa ...
prolactin and autoimmune diseases prolakt
... is an important lymphocyte growth factor. In most experimental systems, however, adding prolactin directly to cultures of lymphoid cells does not stimulate mitogenesis. The sensitivity of the cultures to specific concentrations of prolactin, the biphasic effect of prolactin on mitogenesis in culture ...
... is an important lymphocyte growth factor. In most experimental systems, however, adding prolactin directly to cultures of lymphoid cells does not stimulate mitogenesis. The sensitivity of the cultures to specific concentrations of prolactin, the biphasic effect of prolactin on mitogenesis in culture ...
Molecular Cloning of Dog Mast Cell Tryptase and a Related Protease
... by this neuropeptide which is believed to modulate neural nonadrenergic relaxation in airways (Caughey et al., 1988b; Franconi et al., 1989); the enzyme also potentiates the smooth muscle contractile effects of mediators such as histamine This work supported by Grants HL-24136 (J.A.N.), HL-01736 (G. ...
... by this neuropeptide which is believed to modulate neural nonadrenergic relaxation in airways (Caughey et al., 1988b; Franconi et al., 1989); the enzyme also potentiates the smooth muscle contractile effects of mediators such as histamine This work supported by Grants HL-24136 (J.A.N.), HL-01736 (G. ...
Pathogenic Microbes and Community Service
... bacterium generates high levels of C5a in vitro and in vivo (Wang et al. 2010; Liang et al. 2010). This is quite curious for a pathogen which goes at great lengths to inhibit all three known initiation mechanisms of complement activation (Popadiak et al. 2007; Krauss et al. 2010). However, there is ...
... bacterium generates high levels of C5a in vitro and in vivo (Wang et al. 2010; Liang et al. 2010). This is quite curious for a pathogen which goes at great lengths to inhibit all three known initiation mechanisms of complement activation (Popadiak et al. 2007; Krauss et al. 2010). However, there is ...
The physiology of blood platelets and changes of their biological
... (junctional adhesion molecule) and PECAM‑1 (platelet endothelial cell adhesion molecule‑1). These molecules may interact with other cells. On the platelet membranes glycoprotein complex (GPIb‑V‑IX) is involved in the interaction of platelets with exposed subendothelium through binding to vWf. GPVI m ...
... (junctional adhesion molecule) and PECAM‑1 (platelet endothelial cell adhesion molecule‑1). These molecules may interact with other cells. On the platelet membranes glycoprotein complex (GPIb‑V‑IX) is involved in the interaction of platelets with exposed subendothelium through binding to vWf. GPVI m ...
Chronic inflammation
... Activated macrophages secrete bio-oxidant that initiate lipid peroxidation in the membrane of other cells in the infiltrated area. However, simply increasing chemotaxin in some tissue site has not meant to influx of new inflammatory effector cells from the blood. It is necessary that along with the ...
... Activated macrophages secrete bio-oxidant that initiate lipid peroxidation in the membrane of other cells in the infiltrated area. However, simply increasing chemotaxin in some tissue site has not meant to influx of new inflammatory effector cells from the blood. It is necessary that along with the ...
Studies on the antimicrobial defence of human hair follicle epithelium
... jedermann benutzt werden dürfen. This document is protected by copyright law. No part of this document may be reproduced in any form by any means without prior written authorization of the publisher. ...
... jedermann benutzt werden dürfen. This document is protected by copyright law. No part of this document may be reproduced in any form by any means without prior written authorization of the publisher. ...
Preeclampsia and the Systemic Inflammatory Response
... The major interface between mother and fetus, the large syncytiotrophoblast layer, expresses no known polymorphic major histocompatibility (HLA) antigens. Histocompatibility antigens are the targets for immune rejection that are executed by cytotoxic T cells. However, because the placental hemochori ...
... The major interface between mother and fetus, the large syncytiotrophoblast layer, expresses no known polymorphic major histocompatibility (HLA) antigens. Histocompatibility antigens are the targets for immune rejection that are executed by cytotoxic T cells. However, because the placental hemochori ...
Tumors and Ly6Chigh Monocytes Fatemeh Zare
... support during my studies. I am eternally grateful to my wonderful parents and sister who have always encouraged me in everything and who have been there not only for all the highs , but importantly for all the lows too. Without you I would never have gotten this far. This is for you. ...
... support during my studies. I am eternally grateful to my wonderful parents and sister who have always encouraged me in everything and who have been there not only for all the highs , but importantly for all the lows too. Without you I would never have gotten this far. This is for you. ...
Polyclonal B cell response
Polyclonal B cell response is a natural mode of immune response exhibited by the adaptive immune system of mammals. It ensures that a single antigen is recognized and attacked through its overlapping parts, called epitopes, by multiple clones of B cell.In the course of normal immune response, parts of pathogens (e.g. bacteria) are recognized by the immune system as foreign (non-self), and eliminated or effectively neutralized to reduce their potential damage. Such a recognizable substance is called an antigen. The immune system may respond in multiple ways to an antigen; a key feature of this response is the production of antibodies by B cells (or B lymphocytes) involving an arm of the immune system known as humoral immunity. The antibodies are soluble and do not require direct cell-to-cell contact between the pathogen and the B-cell to function.Antigens can be large and complex substances, and any single antibody can only bind to a small, specific area on the antigen. Consequently, an effective immune response often involves the production of many different antibodies by many different B cells against the same antigen. Hence the term ""polyclonal"", which derives from the words poly, meaning many, and clones (""Klon""=Greek for sprout or twig); a clone is a group of cells arising from a common ""mother"" cell. The antibodies thus produced in a polyclonal response are known as polyclonal antibodies. The heterogeneous polyclonal antibodies are distinct from monoclonal antibody molecules, which are identical and react against a single epitope only, i.e., are more specific.Although the polyclonal response confers advantages on the immune system, in particular, greater probability of reacting against pathogens, it also increases chances of developing certain autoimmune diseases resulting from the reaction of the immune system against native molecules produced within the host.