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Powerpoint 5
Powerpoint 5

... complexity, and physical form are intrinsic properties of immunogens. When foreign immunogens are introduced into a host in an appropriate dose and route, they initiate an immune response. • Antigens are molecules recognized by antibodies or T-Cell-Receptors or TCRs. Antibodies recognize conformatio ...
Micro 532 Exam 1995
Micro 532 Exam 1995

... the tuberculin test is only presumptive, indicating that he has been exposed to a tuberculosis antigen. a chest x-ray will indicate whether there has been granuloma formation due to his inability to clear the bacillus. you are looking for fluid in his lungs due to inflammation caused by the bacillus ...
Exam Key 2 2008
Exam Key 2 2008

... IV. Short Answers/diagram/definitions (total of 50 points. (Be concise and answer in space provided) 1. Define the following terms (3 points each, 15 points total) a. MHC self restricted Thymus development of T helper and cytotoxic T cells that are selected on the basis that they recognize self (at ...
IMMUNOLOGICAL TOLERANCE
IMMUNOLOGICAL TOLERANCE

... Repeated stimulation of T cells results in the coexpression of death receptors and their ligands, and engagement of the death receptors triggers apoptotic death. In CD4+ T cells, the most important death receptor is Fas (CD95), and its ...
Specific Immunity. Antibodies
Specific Immunity. Antibodies

... IgM is the main immunoglobulin produced early in the primary response. It is present as a monomer on the surface of virtually all B cells, where it functions as an antigenbinding receptor. In serum, it is a pentamer composed of 5 H2L2 units plus one molecule of J (joining) chain. Because the pentame ...
Hypersensitivity
Hypersensitivity

... memory B-cells (anti-Rh antibodies) The IgM antibody clears the Rh+ cells from the mother In subsequent pregnancies with an Rh+ fetus, the Rh+ RBC cross the placenta activating the memory B-cells These in turn cross the placenta and damage the fetal RBC because they are seen as “foreign” ...
Lecture 5 T Cell-Mediated Immunity
Lecture 5 T Cell-Mediated Immunity

... Effector cells and antibodies play critical roles in almost all adaptive immune responses  Antigen-presenting cells play critical role in processing and presenting antigen to T cells  Cytokines are released by a variety of cell types and regulate a variety of biological effects  T-cell mediated c ...
Study of the Immune System
Study of the Immune System

... and third lines of defense Functions of a healthy ...
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1Mono Clonal Antibodies (reviewed)

... hypervariable amino acid domains into human antibodies.  This results in a molecule of approximately ...
Non-Specific Defense
Non-Specific Defense

... B cells start to make chemicals called antibodies. Antibodies lock onto foreign antigens making it easier for other immune cells to destroy them. ...
Lymphocytes - MBBS Students Club
Lymphocytes - MBBS Students Club

... Is caused by immune system that form antibodies and/ or activated lymphocytes that attack and destroy the specific invading organism or toxin • Passive immunity--- produced by already made antibodies or activated T cells from horse or ...
2.2 The Importance of Cell Division
2.2 The Importance of Cell Division

... • As a cell gets larger the amount of material in the cell increases faster than the cell membrane can grow • After a while nutrients and waste can’t pass through the membrane in the amounts required and the cell dies ...
Human Bio 11 – Dalesandro
Human Bio 11 – Dalesandro

... 1) Some people think bacteria and viruses give you a fever. No, fever is one of your body’s defense systems. What kind of cell controls whether or not you have a fever? Describe this cell’s appearance. 2) What blood cell contains histamine and controls allergic reactions? Describe this cell’s appear ...
Immunology targets: Explain the role of pathogens in illness
Immunology targets: Explain the role of pathogens in illness

... Virus – non-living, nucleic acids wrapped in protein Parasite – organisms that live on or inside other organisms Infection – invasion by a pathogen Immune System – body system that protects the body from pathogens Mucous membranes – Internal body surfaces that come into contact with the environment ...
Immunology 3 – Innate Immunity
Immunology 3 – Innate Immunity

... monocytes/macrophages. Innate immunity is that which is “inbuilt”, present from birth. It is not antigen-specific, but is able to recognise pathogen-specific molecular patterns. It is the same at every time the body is exposed to an antigen (has no memory). ...
Ch 12 Adaptive Defense Overview
Ch 12 Adaptive Defense Overview

... Humoral immunity  antibody-mediated immunity ...
Forside eksamen bokmål NTNU
Forside eksamen bokmål NTNU

... Cells in a multicellular organism may be associated / bound to each other through direct cell-cell junctions or via the extracellular matrix that surrounds them. a. Describe shortly the various junctions that bind cells together in an animal organism and what functions they have. b. Cadherins have a ...
Document
Document

... A. Hemocytoblasts (stem cells) in the red marrow create new blood cells B. Blood Components 1. 45% hematocrit a. 99% erythrocytes (rbc) i. transport gasses; hemoglobin is the O2 carrying molecule ii. millions of antigens on cell surface (A, B, O, and Rh) which may stimulate the production of antibod ...
A “Y”
A “Y”

Foundations in Microbiology
Foundations in Microbiology

... and its hormones. • 7 classes of T-cell receptors termed CD cluster of differentiation • Mature T cells migrate to lymphoid organs and occupy specific sites. ...
PowerPoint # 3
PowerPoint # 3

... that acts as a microbe, a devouring phagocyte, an antigen presenting cell, and an important source of immune system secretions. • B-cells- Small white blood cells crucial to the immune system defenses. They are also known as B-lymphocytes and they are derived from bone marrow and they develop into p ...
中六生物科教材
中六生物科教材

Antigens
Antigens

... A certain amount of chemical complexity is required, for example, amino acid homopolymers are less immunogenic than heteropolymers containing two or three different amino acids. ...
Dr. Kennett`s Powerpoint set #1
Dr. Kennett`s Powerpoint set #1

... • Bread • Candidiasis – sometimes called thrush or yeast infections, can be very serious in immunodeficient patients ...
Document
Document

... Fetal development – red bone marrow releases lymphocytes Most become t cells, remainder become b cells  B and t cells stay in lymphatic organs. ...
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Polyclonal B cell response



Polyclonal B cell response is a natural mode of immune response exhibited by the adaptive immune system of mammals. It ensures that a single antigen is recognized and attacked through its overlapping parts, called epitopes, by multiple clones of B cell.In the course of normal immune response, parts of pathogens (e.g. bacteria) are recognized by the immune system as foreign (non-self), and eliminated or effectively neutralized to reduce their potential damage. Such a recognizable substance is called an antigen. The immune system may respond in multiple ways to an antigen; a key feature of this response is the production of antibodies by B cells (or B lymphocytes) involving an arm of the immune system known as humoral immunity. The antibodies are soluble and do not require direct cell-to-cell contact between the pathogen and the B-cell to function.Antigens can be large and complex substances, and any single antibody can only bind to a small, specific area on the antigen. Consequently, an effective immune response often involves the production of many different antibodies by many different B cells against the same antigen. Hence the term ""polyclonal"", which derives from the words poly, meaning many, and clones (""Klon""=Greek for sprout or twig); a clone is a group of cells arising from a common ""mother"" cell. The antibodies thus produced in a polyclonal response are known as polyclonal antibodies. The heterogeneous polyclonal antibodies are distinct from monoclonal antibody molecules, which are identical and react against a single epitope only, i.e., are more specific.Although the polyclonal response confers advantages on the immune system, in particular, greater probability of reacting against pathogens, it also increases chances of developing certain autoimmune diseases resulting from the reaction of the immune system against native molecules produced within the host.
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