• Study Resource
  • Explore
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
I. Circulatory System
I. Circulatory System

BSc/Diploma in Medical Laboratory Technology 3 BLT301
BSc/Diploma in Medical Laboratory Technology 3 BLT301

... recognition receptors. Such B cell receptors are antibody molecules. • Once the B cell contacts with an antigen that matches with its receptor molecule, it begins to divide rapidly and its progeny differentiates into Memory B cells and effector B cells and the latter called plasma cells. The memory ...
Cancers of the immune system.
Cancers of the immune system.

... leave the bone marrow and migrate into the thymus; which then produces mature T- Cells. Spleen: it’s made up of B cells, T cells, macrophages, dendrite cells natural killer cells and red blood cells; it cleans the blood and macrophages and dendrite cells bring antigens to T and B cells , which trigg ...
electroporation
electroporation

... Most ES cell lines are derived from one of the many so-called 129 strains of mice. There is a great deal of genetic variation among these strains (see, for example, Simpson, et al, Nature Genetics 16:19-27, 1997), so it is important to know exactly which one gave rise to the ES cell line being targe ...
Diseases of the Immune System lec.3
Diseases of the Immune System lec.3

... responses. DCs in epithelia at sites of virus entry capture the virus and then migrate into the lymph nodes. Once in lymphoid tissues, DCs may pass HIV on to CD4+ Tcells through direct cell–cell contact. Within days after the first exposure to HIV, viral replication can be detected in the lymph node ...
Answers to Mastering Concepts Questions
Answers to Mastering Concepts Questions

... 5. Describe the structure and function of an antibody. An antibody is a Y-shaped protein that matches a specific antigen. Upon encountering an invader with a matching antigen, the antibody binds to the antigen. This may make the antigen more noticeable to macrophages, may inactivate a microbe, or m ...
Lecture 12Immune Responses to Viral Infections
Lecture 12Immune Responses to Viral Infections

Immunol-revision-lecture-3-prof-feighery
Immunol-revision-lecture-3-prof-feighery

... Effect on the immune system varies Sub-types of T helper cells Th1 cells – interferon gamma product Th2 cells – IL-4, IL-5, IL-6 Th17 cells – IL-17 T regulatory cells – IL-10 ...
BOX 7-1 Genetic Blocks in Lymphocyte Maturation
BOX 7-1 Genetic Blocks in Lymphocyte Maturation

... naive lymphocytes do not encounter the antigen for which they are specific, the naive cells die by apoptosis. After activation by antigen, many of the progeny of the activated cells also die as the antigen is eliminated. In all these situations, the lymphocytes do not receive the survival stimuli th ...
Chapter 16 Supplement
Chapter 16 Supplement

... It has been stated that “boosting your immune system is the single most important thing you can do for your health.” Students interested in learning how to improve their immune system should read The Immune Advantage: The Powerful, Natural Immune-Boosting Program to Help You Prevent Disease, Enhance ...
The Immune System and Immunisation
The Immune System and Immunisation

... response (IgM), lasts 3 weeks, memory cells made. • Secondary/subsequent immune response, IgG, faster • It takes 2 weeks to get optimum immune response after vaccination. ...
Blood - Lancaster High School
Blood - Lancaster High School

... – Thrombin + Ca++ converts fibrinogen to fibrin -> forms a mesh that adheres to tissue & traps blood cells and platelets ...
Biology
Biology

... – antibodies=substance that will cling to the antigen on the surface of a pathogen an immobilize the pathogen or cause them to cling together. – Once infection detected by helper T many plasma cells are generated B cells to produce antibodies ...
Hoerner EDAY 2
Hoerner EDAY 2

... Lesson Overview/Procedures/Length of Time to Complete: We  have  learned  quite  a  bit  about  the  human  body  over  the  last  9  or  10  weeks.  An   important  part  of  learning  is  reviewing  to  make  sure  that  you  still  remem ...
Curbing the appetites of the big eaters - MDC Repository
Curbing the appetites of the big eaters - MDC Repository

... amazing array of powerful chemokines, cytokines, enzymes, complement proteins, and regulatory factors. At the same time, they carry receptors for lymphokines that allow them to be “activated” into single-minded pursuit of microbes and tumor cells. After digesting a pathogen, a macrophage will presen ...
Hematopathology
Hematopathology

... • IgD: monomer, small amount in plasma, triggers initial B-cell activation ...
MICR 201 Chap 4 2013 - Cal State LA
MICR 201 Chap 4 2013 - Cal State LA

... Many pathogens enter the host cell through the formation of vesicles. This method provides protection for the pathogen from the host immune response. Some pathogens bind to host cell receptors that trigger endocytosis. This is particularly true of viruses. Phagocytosis is a type of endocytosis that ...
Viruses, HIV, and Aids
Viruses, HIV, and Aids

... Dendritic cells, macrophages, and B-cells are the main antigenpresenting cells that interact with T-cells. B-cells create thousands of plasma cells which each secrete antibodies. ...
ag-ab react
ag-ab react

... Soluble antigen reacts with specific antibody in presence of electrolytes at an optimal temp and pH to form an insoluble precipitate  Flocculation – precipitate remains suspended as floccules ...
Weekly schedule of activities and outcomes
Weekly schedule of activities and outcomes

... Discuss how the structure of immunoglobulins contribute to both their specificity and their effector functions. Explain the basic structure of an antibody molecule. List the five immunoglobulin classes and their biological function Describe organization of Ig genes Describe class switching Define ho ...
Cell Lines Questionnaire For Ascites
Cell Lines Questionnaire For Ascites

Regulation NERVOUS CONTROL CHEMICAL CONTROL I. How
Regulation NERVOUS CONTROL CHEMICAL CONTROL I. How

... for this kind of growth or “movement” are called _________ ...
Pre-Germinated Brown Rice May Possibly Benefit Alzheimer`s Patients
Pre-Germinated Brown Rice May Possibly Benefit Alzheimer`s Patients

- ISpatula
- ISpatula

... from a decrease in cell size . Mechanism of atrophy include combination of decreased protein synthesis and increased protein degradation in cells. reduced metabolic activity and degradation of cellular proteins Autophagy (“self-eating”) is the process in which the starved cell eats its own component ...
Blood Whole blood has two components
Blood Whole blood has two components

... that contains dissolved substances, and (2) formed elements, which are cells and cell fragments. Blood is about 45% formed elements and 55% plasma. Normally more than 99% of the formed elements are red-colored red blood cells. Pale colorless white blood cells and platelets occupy less than 1% of tot ...
< 1 ... 426 427 428 429 430 431 432 433 434 ... 611 >

Polyclonal B cell response



Polyclonal B cell response is a natural mode of immune response exhibited by the adaptive immune system of mammals. It ensures that a single antigen is recognized and attacked through its overlapping parts, called epitopes, by multiple clones of B cell.In the course of normal immune response, parts of pathogens (e.g. bacteria) are recognized by the immune system as foreign (non-self), and eliminated or effectively neutralized to reduce their potential damage. Such a recognizable substance is called an antigen. The immune system may respond in multiple ways to an antigen; a key feature of this response is the production of antibodies by B cells (or B lymphocytes) involving an arm of the immune system known as humoral immunity. The antibodies are soluble and do not require direct cell-to-cell contact between the pathogen and the B-cell to function.Antigens can be large and complex substances, and any single antibody can only bind to a small, specific area on the antigen. Consequently, an effective immune response often involves the production of many different antibodies by many different B cells against the same antigen. Hence the term ""polyclonal"", which derives from the words poly, meaning many, and clones (""Klon""=Greek for sprout or twig); a clone is a group of cells arising from a common ""mother"" cell. The antibodies thus produced in a polyclonal response are known as polyclonal antibodies. The heterogeneous polyclonal antibodies are distinct from monoclonal antibody molecules, which are identical and react against a single epitope only, i.e., are more specific.Although the polyclonal response confers advantages on the immune system, in particular, greater probability of reacting against pathogens, it also increases chances of developing certain autoimmune diseases resulting from the reaction of the immune system against native molecules produced within the host.
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report