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lymphatic - Ruhr-Universität Bochum
lymphatic - Ruhr-Universität Bochum

... 2. Homing of T-cells and direct CD8 T-cell action (Janeway 439-443, 11.6-11.8); Antibody response in infection ...
ASAHL antibody - middle region (ARP44939_P050)
ASAHL antibody - middle region (ARP44939_P050)

Immune Dysfunction In Myalgic Encephalomyelitis/ Chronic Fatigue
Immune Dysfunction In Myalgic Encephalomyelitis/ Chronic Fatigue

... What is supposed to happen when a healthy person encounters an intracellular organism? The regular form of Rnase-L inhibits viral replication, the immune system revs up and wipes out the virus, then everything down-regulates, and they recover. But unfortunately that is not what happens in CFIDS. In ...
panace@ 20.indd
panace@ 20.indd

... Many of these molecules increase the adhesion of T cells to other cells, promoting optimal interaction between T helper and antigen presenting cells (APC) or between cytotoxic T cells and their respective target cells. ...
Powerpoint
Powerpoint

... products of the innate response, they change, and move from the local area through the lymphatics to the draining lymph node (next slide) as they mature into the best antigen-presenting cells. • Iccosomes are clumps of stored antigen-antibody immune complexes, which allow the dendritic cell to stimu ...
File - Intervention
File - Intervention

...  Cardiac muscle cells are found only in the heart. These cells are striated like skeletal muscle cells, but are smaller and usually only have one or two nuclei.  Smooth muscle cells are found in organs such as the stomach and intestines. These cells are not striated.  Blood Cells: 3 Main Types  ...
Exam Review Part 2: Energy Conversions, Enezymes, and Cells
Exam Review Part 2: Energy Conversions, Enezymes, and Cells

... from ADP and inorganic phosphate via substrate level phosphorylation and electrons are captured by coenzymes (NAD+ and FAD). NADH and FADH2 carry them to the electron transport chain. (5) The electron transport chain captures in a process similar to light dependent reactions to make ATP. (6) At end ...
mid-term-exam-versio..
mid-term-exam-versio..

... A protein’s amino acids are linked by peptide bonds involving the amino group of one amino acid and the carboxyl of another. ...
White Blood Cells
White Blood Cells

... •The main difference between the blood flowing in the circulatory system and the lymph flowing in the lymph system is that blood is pressurized by the heart, while the lymph system is passive. •There is no "lymph pump" like there is a "blood pump" (the heart). •Instead, fluids ooze into the lymph sy ...
Innate Immune Mechanisms: Nonself Recognition
Innate Immune Mechanisms: Nonself Recognition

... the receptor can be expressed by many other cell types, such as some endothelial cells, some smooth muscle cells, and kidney mesangial cells. It seems likely that these expression patterns relate to other functions of the receptor not necessarily involved in innate immunity. For example, the recepto ...
view full article - Nestlé Nutrition Institute
view full article - Nestlé Nutrition Institute

... The functional attributes of thymus-derived T-cells include delayed hypersensitivity reactions, production of lymphokines, killing of tumor cells, lysis of virusinfected cells, and transplantation rejection. In individuals above the âge of 65 years, delayed cutaneous hypersensitivity reactions to ub ...
Antigen sampling and presentation
Antigen sampling and presentation

... ‰ Immunogens refer to antigens that are able to stimulate a specific adaptive immune response when introduced into the body. Not all antigens are immunogens. ‰ To be immunogenic, antigens must fulfill certain criteria ‰ Hapten are small molecules that need a carrier to be immunogenic ...
Chapter 30 Microbial Interactions (미생물의 상호작용) 1
Chapter 30 Microbial Interactions (미생물의 상호작용) 1

... • Toxin (독소) – Specific substance that damages host ...
Lecture Exam 1 Study Guide
Lecture Exam 1 Study Guide

... - Describe the properties of enzymes. How do enzymes increase the rate of chemical reactions? What is a substance that binds to an enzyme called? What site on the enzyme does the substance bind to? - What are cofactors and coenzymes? - What 3 factors affect enzyme reaction rates? How is enzyme activ ...
Topic I Cells - JSH Elective Science with Ms. Barbanel
Topic I Cells - JSH Elective Science with Ms. Barbanel

... • Because enzymes are composed of proteins, their shape is important to their function. • If you change the shape of the protein that composes the enzyme you alter or destroy the enzyme. ...
PHG 413 lecture
PHG 413 lecture

... foreign, destroys them, and 'remembers' them. When the virulent version of an agent comes along the body recognizes the protein coat on the virus, and thus is prepared to respond, by (1) neutralizing the target agent before it can enter cells, and (2) by recognizing and destroying infected cells bef ...
NAME KS3 revision booklet Biology
NAME KS3 revision booklet Biology

Figures from: Martini, Anatomy & Physiology
Figures from: Martini, Anatomy & Physiology

... *Chromatin – combination of DNA plus histone proteins used to pack DNA in the cell nucleus Gene – segment of DNA that codes for a protein or RNA - About 30,000 protein-encoding genes in humans - DNA’s instructions are ultimately responsible for the ability of the cell to make ALL its components Geno ...
Amino acids
Amino acids

...  Amino acids are the basic subunits of proteins.  Each amino acid contains the following parts: ...
PowerPoint Presentation - I. Introduction to class
PowerPoint Presentation - I. Introduction to class

... Metals Latex in gloves and condoms (3% of health care workers) ...
Hi all, and so it begins with Week 1
Hi all, and so it begins with Week 1

... segmented neutrophils (segs). These cells are most numerous in the blood because of their capacity for phagocytosis, especially pathogenic bacteria (Garrels and Oatis, 2006). Neutrophils are the predominant phagocytes in early inflammation, within 6-12 hours of injury. Their job is to ingest bacteri ...
Cytokines In Health and Disease General Properties of Cytokines
Cytokines In Health and Disease General Properties of Cytokines

... o When innate immune response is very strong against a virus  IL-12 and type I IFNs are most important for CTL response  After naïve T cell receives first two signals necessary for activation, a third signal from IL-12 (or type I IFNs) is required for further proliferation of CTLs  Effector CTLs ...
Department of Surgery Research Day
Department of Surgery Research Day

... stroma (TAS) is activated via an innate immune response to PC cells and, as a direct result, suppresses adaptive immunity. Methods: Primary patient-derived TAS innate immune responses were probed to both known ligands and PC cell conditioned media. TAS innate immune function was then evaluated using ...
Innate Immunity PowerPoint
Innate Immunity PowerPoint

... C) Lactobacillus 1) produce lactic acid in the vagina causing the pH to be too low for other bacteria to survive ...
Slide 1
Slide 1

... • Results in infiltration of lymphocytes and macrophages, and subsequent proliferation of T lymphocytes (T-cells), at site of injection • Measures cell-mediated immune function: activation of macrophages, natural killer cells, cytotoxic T-cells and cytokines (NOT antibodies) ...
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Polyclonal B cell response



Polyclonal B cell response is a natural mode of immune response exhibited by the adaptive immune system of mammals. It ensures that a single antigen is recognized and attacked through its overlapping parts, called epitopes, by multiple clones of B cell.In the course of normal immune response, parts of pathogens (e.g. bacteria) are recognized by the immune system as foreign (non-self), and eliminated or effectively neutralized to reduce their potential damage. Such a recognizable substance is called an antigen. The immune system may respond in multiple ways to an antigen; a key feature of this response is the production of antibodies by B cells (or B lymphocytes) involving an arm of the immune system known as humoral immunity. The antibodies are soluble and do not require direct cell-to-cell contact between the pathogen and the B-cell to function.Antigens can be large and complex substances, and any single antibody can only bind to a small, specific area on the antigen. Consequently, an effective immune response often involves the production of many different antibodies by many different B cells against the same antigen. Hence the term ""polyclonal"", which derives from the words poly, meaning many, and clones (""Klon""=Greek for sprout or twig); a clone is a group of cells arising from a common ""mother"" cell. The antibodies thus produced in a polyclonal response are known as polyclonal antibodies. The heterogeneous polyclonal antibodies are distinct from monoclonal antibody molecules, which are identical and react against a single epitope only, i.e., are more specific.Although the polyclonal response confers advantages on the immune system, in particular, greater probability of reacting against pathogens, it also increases chances of developing certain autoimmune diseases resulting from the reaction of the immune system against native molecules produced within the host.
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