PPT - Fat Tuesday Productions
... cells (LC) in the epidermis of the skin. The urushiols are displayed on the surface of the cell by an MHC I molecule. Some of the LC cells then travel to the lymph nodes (see picture) where T cells will be activated toward the urushiols in those with an allergy to them. ...
... cells (LC) in the epidermis of the skin. The urushiols are displayed on the surface of the cell by an MHC I molecule. Some of the LC cells then travel to the lymph nodes (see picture) where T cells will be activated toward the urushiols in those with an allergy to them. ...
Ch 12 - Lymphatic System
... the bone marrow; produce antibodies, oversee humoral immunity. – T lymphocytes (T cells) become immunocompetent in the thymus; – Originate from hemocytoblasts in the red bone marrow • Macrophages – Arise from monocytes – Become widely distributed in lymphoid organs – Do not respond to specific antig ...
... the bone marrow; produce antibodies, oversee humoral immunity. – T lymphocytes (T cells) become immunocompetent in the thymus; – Originate from hemocytoblasts in the red bone marrow • Macrophages – Arise from monocytes – Become widely distributed in lymphoid organs – Do not respond to specific antig ...
幻灯片 1
... TI-1 antigen: also named B cell mitogen 1. Contains B cell mitogen and repeated B epitopes 2. Can induce immature and mature B cell-mediate immune response 3. In high concentrations, can induce polyclonal B-cell activation 4. In lower concentrations, only the BCR-binding TI-1 antigens can activate ...
... TI-1 antigen: also named B cell mitogen 1. Contains B cell mitogen and repeated B epitopes 2. Can induce immature and mature B cell-mediate immune response 3. In high concentrations, can induce polyclonal B-cell activation 4. In lower concentrations, only the BCR-binding TI-1 antigens can activate ...
Slayt 1
... There are 14 KIR genes and two pseudogenes located in the leukocyte receptor complex (LRC) on chromosome 19q13.4. Human NK cells express various combinations of these 16 KIR genes with two common haplotypes: Group A, which has more inhibitory receptors and Group B, which has more activating ...
... There are 14 KIR genes and two pseudogenes located in the leukocyte receptor complex (LRC) on chromosome 19q13.4. Human NK cells express various combinations of these 16 KIR genes with two common haplotypes: Group A, which has more inhibitory receptors and Group B, which has more activating ...
Immunity Notes - shscience.net
... - the ability of the body’s blood to defend against infection - our immune system protects us from pathogens (any organism/protein-structure that cause disease) - in fact, our immune system is what helps us recognize pathogens as foreign objects so we can destroy them ...
... - the ability of the body’s blood to defend against infection - our immune system protects us from pathogens (any organism/protein-structure that cause disease) - in fact, our immune system is what helps us recognize pathogens as foreign objects so we can destroy them ...
Exporter la page en pdf
... critical for IFN and inflammatory gene expression during innate immune responses. However, the role of STING in adaptive immunity is still unknown. In this study, we show that STING activation reduces the proliferation of T lymphocytes. This activity was independent of TBK1 and IRF3 recruitment and o ...
... critical for IFN and inflammatory gene expression during innate immune responses. However, the role of STING in adaptive immunity is still unknown. In this study, we show that STING activation reduces the proliferation of T lymphocytes. This activity was independent of TBK1 and IRF3 recruitment and o ...
Anatomy chapter 14 (Lymphatic and immunity)
... •They are covered with connective tissue that extends inside the node and divides it into nodules and spaces called sinuses. •These contain both lymphocytes and macrophages which clean the lymph as it flows through the node. •Lymph nodes are centers of lymphocyte production, which function in immune ...
... •They are covered with connective tissue that extends inside the node and divides it into nodules and spaces called sinuses. •These contain both lymphocytes and macrophages which clean the lymph as it flows through the node. •Lymph nodes are centers of lymphocyte production, which function in immune ...
Immunology for Life Scientists. 2nd Edition Brochure
... 1.1.4 Cells involved in the specific immune response. Lymphocytes. T cells. B cells. Key points for review. ...
... 1.1.4 Cells involved in the specific immune response. Lymphocytes. T cells. B cells. Key points for review. ...
System has Specificity and Memory
... fragments are in a state that lymphocytes can be stimulated. Antigen presentation is in the context of the major histocompatibility complex (MHC). ...
... fragments are in a state that lymphocytes can be stimulated. Antigen presentation is in the context of the major histocompatibility complex (MHC). ...
Case study slides by Lara Alshabatat
... Mild form of combined immunodeficiency . progressive infection with the attenuated live vaccine strain BCG has not been observed in MHC class II-deficient patients after BCG ...
... Mild form of combined immunodeficiency . progressive infection with the attenuated live vaccine strain BCG has not been observed in MHC class II-deficient patients after BCG ...
Southern Methodist University
... amino acids, designed to mimic myelin basic protein, an important component of CNS myelin. Believed to work by activating anti-inflammatory regulatory T cells, which then migrate into the CNS to inhibit local immune rxns. ...
... amino acids, designed to mimic myelin basic protein, an important component of CNS myelin. Believed to work by activating anti-inflammatory regulatory T cells, which then migrate into the CNS to inhibit local immune rxns. ...
Name - Medical Mastermind Community
... MATCHING: For each numbered item, (Column 1), choose the most appropriate answer (Column 2). FOR ALL MATCHNG QUESTIONS each answer may be used once, more than once or not at all. 61. Ig that can be either bivalent or tetravalent, may or may not posses a J chain peptide covalently bound to it 62. In ...
... MATCHING: For each numbered item, (Column 1), choose the most appropriate answer (Column 2). FOR ALL MATCHNG QUESTIONS each answer may be used once, more than once or not at all. 61. Ig that can be either bivalent or tetravalent, may or may not posses a J chain peptide covalently bound to it 62. In ...
Antibodies, B cell, T cell
... with class I MHC-antigen complexes on an infected cell and by IL-2 from a helper T cell. • The activated cytotoxic T cell differentiates into an active killer, which kills its target cell - the antigenpresenting cell - primarily by releasing perforin. • This protein forms pores into the target cell, ...
... with class I MHC-antigen complexes on an infected cell and by IL-2 from a helper T cell. • The activated cytotoxic T cell differentiates into an active killer, which kills its target cell - the antigenpresenting cell - primarily by releasing perforin. • This protein forms pores into the target cell, ...
Immunity - Seattle Central College
... – caused by increased blood flow & vascular permeability – Chemicals and swelling activate pain receptors ...
... – caused by increased blood flow & vascular permeability – Chemicals and swelling activate pain receptors ...
Immunity and How it Works
... cells; identifies and neutralises pathogens Antigen: substance that can provoke an immune response Clone: group of identical decendents Epitope: the specific piece of the antigen to which an ...
... cells; identifies and neutralises pathogens Antigen: substance that can provoke an immune response Clone: group of identical decendents Epitope: the specific piece of the antigen to which an ...
Practice Exam 2 with answers
... b. IP3 directly activates protein kinase C (PKC) which activates NFB c. IP3 acts to dephosphoylate and activate NFAT d. IP3 acts as a suppressor signal by blocking phosphorylation of p56lck to regulate activation e. IP3 diffuses rapidly to the nucleus and acts as a transcription factor to turn on i ...
... b. IP3 directly activates protein kinase C (PKC) which activates NFB c. IP3 acts to dephosphoylate and activate NFAT d. IP3 acts as a suppressor signal by blocking phosphorylation of p56lck to regulate activation e. IP3 diffuses rapidly to the nucleus and acts as a transcription factor to turn on i ...
vocab 4 s08 - Biology Courses Server
... acquired immune response. (Note: the word originated from the notion of being something that could stimulate antibody generation. It is now known, however, that an antigen can stimulate other forms of acquired immune responses besides antibody production. ) antigen-presenting cell – a cell that spec ...
... acquired immune response. (Note: the word originated from the notion of being something that could stimulate antibody generation. It is now known, however, that an antigen can stimulate other forms of acquired immune responses besides antibody production. ) antigen-presenting cell – a cell that spec ...
Humoral Immune Response
... Accounts for less than 1% of Ig pool. Primarily a cell bound Ig found on the surface of B lymphocytes. Despite studies extending for more than 4 decades, a specific role for serum IgD has not been defined while for IgD bound to the membrane of many B lymphocytes, several functions have been proposed ...
... Accounts for less than 1% of Ig pool. Primarily a cell bound Ig found on the surface of B lymphocytes. Despite studies extending for more than 4 decades, a specific role for serum IgD has not been defined while for IgD bound to the membrane of many B lymphocytes, several functions have been proposed ...
Peripheral tolerance in T cells
... • What is their mechanisms of actions? • Are they beneficial (for the prevention of autoimmunity, allergy and graft rejection)? • Are they harmful (in terms of their effects on tumor immunity, immune response to chronic infections and weak vaccines)? ...
... • What is their mechanisms of actions? • Are they beneficial (for the prevention of autoimmunity, allergy and graft rejection)? • Are they harmful (in terms of their effects on tumor immunity, immune response to chronic infections and weak vaccines)? ...
Specific Defenses of the Host - Suffolk County Community College
... -chemical messengers used within immune system (proteins or glycoproteins) -many kinds, each has specific message Cells = T cells -originate from stem cells in bone marrow but mature in thymus, travel to blood & lymph -each only recognizes one antigen -when it binds to antigen, will undergo clonal s ...
... -chemical messengers used within immune system (proteins or glycoproteins) -many kinds, each has specific message Cells = T cells -originate from stem cells in bone marrow but mature in thymus, travel to blood & lymph -each only recognizes one antigen -when it binds to antigen, will undergo clonal s ...
Cells of the Immune System and Antigen Recognition Jennifer Nyland, PhD
... Four principles of clonal selection Hθ 1. Each lymphocyte has a SINGLE type of AgR 2. Interaction between foreign molecule and AgR with high affinity leads to activation 3. Differentiated effector cell derived from activated lymphocyte with have the same AgR as parental lymphocyte (clones) 4. Lymph ...
... Four principles of clonal selection Hθ 1. Each lymphocyte has a SINGLE type of AgR 2. Interaction between foreign molecule and AgR with high affinity leads to activation 3. Differentiated effector cell derived from activated lymphocyte with have the same AgR as parental lymphocyte (clones) 4. Lymph ...
Adaptive immune system
The adaptive immune system, also known as the acquired immune or, more rarely, as the specific immune system, is a subsystem of the overall immune system that is composed of highly specialized, systemic cells and processes that eliminate or prevent pathogen growth. The adaptive immune system is one of the two main immunity strategies found in vertebrates (the other being the innate immune system). Adaptive immunity creates immunological memory after an initial response to a specific pathogen, leads to an enhanced response to subsequent encounters with that pathogen. This process of acquired immunity is the basis of vaccination. Like the innate system, the adaptive system includes both humoral immunity components and cell-mediated immunity components.Unlike the innate immune system, the adaptive immune system is highly specific to a specific pathogen. Adaptive immunity can also provide long-lasting protection: for example; someone who recovers from measles is now protected against measles for their lifetime but in other cases it does not provide lifetime protection: for example; chickenpox. The adaptive system response destroys invading pathogens and any toxic molecules they produce. Sometimes the adaptive system is unable to distinguish foreign molecules, the effects of this may be hayfever, asthma or any other allergies. Antigens are any substances that elicit the adaptive immune response. The cells that carry out the adaptive immune response are white blood cells known as lymphocytes. Two main broad classes—antibody responses and cell mediated immune response—are also carried by two different lymphocytes (B cells and T cells). In antibody responses, B cells are activated to secrete antibodies, which are proteins also known as immunoglobulins. Antibodies travel through the bloodstream and bind to the foreign antigen causing it to inactivate, which does not allow the antigen to bind to the host.In acquired immunity, pathogen-specific receptors are ""acquired"" during the lifetime of the organism (whereas in innate immunity pathogen-specific receptors are already encoded in the germline). The acquired response is called ""adaptive"" because it prepares the body's immune system for future challenges (though it can actually also be maladaptive when it results in autoimmunity).The system is highly adaptable because of somatic hypermutation (a process of accelerated somatic mutations), and V(D)J recombination (an irreversible genetic recombination of antigen receptor gene segments). This mechanism allows a small number of genes to generate a vast number of different antigen receptors, which are then uniquely expressed on each individual lymphocyte. Because the gene rearrangement leads to an irreversible change in the DNA of each cell, all progeny (offspring) of that cell inherit genes that encode the same receptor specificity, including the memory B cells and memory T cells that are the keys to long-lived specific immunity.A theoretical framework explaining the workings of the acquired immune system is provided by immune network theory. This theory, which builds on established concepts of clonal selection, is being applied in the search for an HIV vaccine.