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Teil 1: „Studies on the extracellular matrix enzyme
Teil 1: „Studies on the extracellular matrix enzyme

... LOX-like genes encoding proteins that share a highly conserved C-terminus but are rather diverse at their N-termini (Figure 1). Researchers observed from early on that chromatographic separation of purified LOX from tissue extracts yielded multiple isoforms leading to the hypothesis that several LOX ...
Review - American Physiological Society
Review - American Physiological Society

... Cellular immunity: Involves the production of lymphocytes by the thymus (T cells) in response to exposure to an antigen. Codon: A sequence of 3 nucleotides in a strand of DNA that provides the genetic code for a specific amino acid. COL1A1: Gene encoding the ␣1 chain of type I collagen. COL1A2: Gene ...
GAS6 is a key homeostatic immunological regulator of host
GAS6 is a key homeostatic immunological regulator of host

... Maintaining immune homeostasis is an active and complex process requiring vast interplays among hematopoietic and nonhematopoietic cells such as epithelial cells. Recently, the TAM receptors: TYRO3, AXL, and MERTK and their ligands: growth arrest-specific 6 (GAS6) and protein S (PROS1) were shown to ...
Elevated serum BAFF levels in patients with sarcoidosis: association
Elevated serum BAFF levels in patients with sarcoidosis: association

Pregnancy enhances the innate immune response in experimental cutaneous leishmaniasis through
Pregnancy enhances the innate immune response in experimental cutaneous leishmaniasis through

... Furthermore, female mice or hamsters were shown to be more resistant to cutaneous leishmaniasis (caused by Leishmania mexicana and Leishmania (Viannia) panamensis, respectively) than males, and this difference depended, at least in hamsters, on the levels of circulating sex hormones [30, 31]. In thi ...
Rhesus rhadinovirus vIRF R12 disrupts the PML
Rhesus rhadinovirus vIRF R12 disrupts the PML

... herpesvirus (KSHV) infection. However, the scarcity of animal models for studying de novo KSHV infection, as well as KSHV-associated diseases greatly hindered these processes, leading to the emergence of using other primate viruses to study the KSHV. Rhesus macaque rhadinovirus (RRV), a monkey γ2 he ...
the innate immunity in bovine mastitis
the innate immunity in bovine mastitis

... signaling pathways. The Intramammary Infections (IMIs) by this bacteria result in a very moderate host response with minimal observable innate immune response, which are related to well-known ability to this pathogen to establish chronic IMI. Otherwise, E. coli elicits a strong and earlier response, ...
IDENTIFICATION OF  THE SEROTYPE-SPECIFIC AND  GROUP-SPECIFIC
IDENTIFICATION OF THE SEROTYPE-SPECIFIC AND GROUP-SPECIFIC

... Immune precipitation with guinea-pig antisera Soluble 14 C-labelled polypeptides of a number of different BTV serotypes were immune-precipit~ted with guinea-pig immune sera prepared agamst homologous and heterologous serotypes. The s~ra were those routinely used for serotypmg BTV strams and show ver ...
Gut Bacteria Metabolism Impacts Immune Recovery in HIV
Gut Bacteria Metabolism Impacts Immune Recovery in HIV

... gut environment. However, our findings provide also evidences suggesting the contribution of gut bacteria to ART-mediated immune recovery. Changes in the gut ecosystem in HIV-infected patients undergoing ART may thus be both a consequence and a potential cause of the recovery of mucosal and systemic ...
HIV-1 Envelope gp41 Is a Potent Inhibitor of Chemoattractant
HIV-1 Envelope gp41 Is a Potent Inhibitor of Chemoattractant

... by gp120/CD4 complex. The interaction between gp120 and coreceptors then induces a structural change in gp41 culminating in a fusogenic state (6). Gp41 is thought to mediate fusion between viral and cellular membranes (7, 8) by the insertion of the hydrophobic amino terminus into the plasma membrane ...
and Progression of Acute Allograft Rejection Cardiac Grafts
and Progression of Acute Allograft Rejection Cardiac Grafts

... remain a significant problem in allograft function and loss (1). Furthermore, recent clinical studies have clearly indicated that acute rejection episodes are a critical risk factor for the subsequent development of chronic rejection, the leading cause of cardiac allograft loss (2, 3). The key facto ...
Assessment of allergen specific response in humans Luis Diego Archila Diaz
Assessment of allergen specific response in humans Luis Diego Archila Diaz

... V. CD4+ T cells contribute to allergic disease ................................................................................... 68 V.1. The role of TH2 cells in allergic inflammation ........................................................................... 68 V.2. The role of TH1 cells in aller ...
HIV-specific antibody- dependent cellular cytotoxicity
HIV-specific antibody- dependent cellular cytotoxicity

Intestinal Dendritic Cells Specialize to Activate Transforming Growth
Intestinal Dendritic Cells Specialize to Activate Transforming Growth

... enter the digestive tract. A breakdown in this tight regulation can lead to debilitating autoimmunity and inflammatory bowel disease. Strong evidence exists that CD4⫹ regulatory T cells (Tregs) play a crucial role in regulating inflammatory responses at environmental interfaces such as the gut.2 The ...
- studijní a informační středisko vfu brno
- studijní a informační středisko vfu brno

... the first meiotic division and become primary oocytes which are diploid (period of growth). They become arrested at the diplotene phase. A primary oocyte surrounded by a single layer of squamous follicular cells is known as a primordial follicle. The primordial follicles present the pool of quiescen ...
lymphatic system
lymphatic system

... Before birth, the body makes an inventory of "self" proteins and other large molecules. b. After inventory, lymphocytes develop receptors that allow them to differentiate between nonself (foreign) and self antigens. c. Nonself antigens combine with T-cell and B-cell surface receptors and stimulate t ...
lymphatic system
lymphatic system

... a.Before birth, the body makes an inventory of "self" proteins and other large molecules. b. After inventory, lymphocytes develop receptors that allow them to differentiate between nonself (foreign) and self antigens. c. Nonself antigens combine with T-cell and B-cell surface receptors and stimulate ...
CellularandMolecularMechanisms ofBoneRemodeling*
CellularandMolecularMechanisms ofBoneRemodeling*

Aloe Vera and the Human Immune System
Aloe Vera and the Human Immune System

... effectshavebeenclearlyshownto be of functionalbenefit. Next, it is clear,ffid well known, that the body's fight agairst tumoursis alsomediated throughthe immunesptenl which hasan ability to kill andremovetumotr cells. The outcomeis presumedto be determinedrnainlyby the vigour of the immruresystem re ...
A Diagnostic Target Against Clostridium bolteae
A Diagnostic Target Against Clostridium bolteae

... capsular polysaccharide comprised of rhamnose and mannose units: [3)-α-D-Manp(14)-β-D-Rhap-(1], which is immunogenic in rabbits. This is the first described immunogen of C. bolteae and indicates the prospect of using this polysaccharide as a vaccine to reduce or prevent colonization of the intest ...
- Wiley Online Library
- Wiley Online Library

... Akira 2001). Some TLRs also bind to nucleic acids, DNA or RNA, shared by all microorganisms (TLR9 and TLR7 recognize DNA and RNA, respectively). NLRs are cytosolic proteins that respond to various PAMPs from bacteria (lipoproteins, pore-forming toxins, RNA), viruses (RNA), fungi, and parasites (Kawa ...
Allergic disease: the diagnosis of peanut allergy and the role of heat
Allergic disease: the diagnosis of peanut allergy and the role of heat

RAJIV GANDHI UNIVERSITY OF HEALTH SCIENCES
RAJIV GANDHI UNIVERSITY OF HEALTH SCIENCES

... lysozymes and other secreted substances; cell-mediated responses involve a wide number of cell types, including phagocytes (neutrophils, monocytes/macrophages, and dendritic cells), natural killer cells (NK cells), basophils, mast cells and eosinophils. In the adaptive or specific immune system, hum ...
Tissue-Expressed B7x Affects the Immune Response to and and
Tissue-Expressed B7x Affects the Immune Response to and and

... B7x protein is expressed in the lung, but not in lymphoid tissues Previously, B7x mRNA expression was detected in both lymphoid and peripheral nonlymphoid tissues (3–5). However, levels in nonlymphoid tissues, such as the lung, were much higher than in lymphoid tissues (3, 6). In this study, we used ...
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Adoptive cell transfer

Adoptive cell transfer (ACT) is the transfer of cells into a patient; as a form of cancer immunotherapy. The cells may have originated from the patient him- or herself and then been altered before being transferred back, or, they may have come from another individual. The cells are most commonly derived from the immune system, with the goal of transferring improved immune functionality and characteristics along with the cells back to the patient. Transferring autologous cells, or cells from the patient, minimizes graft-versus-host disease (GVHD) or what is more casually described as tissue or organ rejection.
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