ImmuCo: a database of gene co-expression in
... protein interactions, cellular signaling activity and gene regulation are frequently analyzed in the same cells (such as tumor cell lines) for most experiments. Thus, correlation analysis within the same cell type no doubt provides more accurate and reliable results to guide experiments. The recentl ...
... protein interactions, cellular signaling activity and gene regulation are frequently analyzed in the same cells (such as tumor cell lines) for most experiments. Thus, correlation analysis within the same cell type no doubt provides more accurate and reliable results to guide experiments. The recentl ...
NAD+-Consuming Enzymes in the Regulation of Lung Immune
... ing but not in normal volunteers [27]. ART1 has been shown to possess pro-inflammatory functions as its inhibitors, metaiodobenzyl-guanidine and novobiocine, suppress the lipopolysaccharide (LPS)-induced production of IL-6 and IL-8 in human lung epithelial cells [28]. Furthermore, ART1 was upregulat ...
... ing but not in normal volunteers [27]. ART1 has been shown to possess pro-inflammatory functions as its inhibitors, metaiodobenzyl-guanidine and novobiocine, suppress the lipopolysaccharide (LPS)-induced production of IL-6 and IL-8 in human lung epithelial cells [28]. Furthermore, ART1 was upregulat ...
An introduction to immunology
... • Important to study what parts of a protein that binds to MHC molecules. • MHC I binds peptides with 8-10 aa • MHC II bind peptides with 12-25 aa • Potentials of peptide vaccines • Prediction of peptides is important!!!! ...
... • Important to study what parts of a protein that binds to MHC molecules. • MHC I binds peptides with 8-10 aa • MHC II bind peptides with 12-25 aa • Potentials of peptide vaccines • Prediction of peptides is important!!!! ...
Stem cells and aging from a quasiimmortal point of view
... complexity of the Wnt signaling network [87]. The Wnt/bCatenin pathway also plays a role in the maintenance and in cell fate decisions of stem cells, and activated Wnt signaling is tightly linked to stemness [88]. Transcription factors of the Myc family may also play a decisive role in the control o ...
... complexity of the Wnt signaling network [87]. The Wnt/bCatenin pathway also plays a role in the maintenance and in cell fate decisions of stem cells, and activated Wnt signaling is tightly linked to stemness [88]. Transcription factors of the Myc family may also play a decisive role in the control o ...
The Cell Biology of Multi-nucleated Giant Cell Formation
... compartment (Vignery, 2005). A foreign-body giant cell is a collection of fused ...
... compartment (Vignery, 2005). A foreign-body giant cell is a collection of fused ...
UNIT 6 – READING AND LEARNING GUIDE TOPICS TO KNOW
... Describe the characteristics of the immune response that can be generated by humans and indicate the components in each phase of this response. Give examples of cell types involved in innate immune defenses and explain their roles. Describe the purpose of the inflammatory response. Give examples of ...
... Describe the characteristics of the immune response that can be generated by humans and indicate the components in each phase of this response. Give examples of cell types involved in innate immune defenses and explain their roles. Describe the purpose of the inflammatory response. Give examples of ...
Use of carbohydrates and peptides in studies of adhesion of
... environment and play important roles in processes such as cell growth and differentiation. In addition, viruses, bacteria, and bacterial toxins use the protruding carbohydrate moieties as specific sites of attachment in infectious processes. Glycolipids belonging to the globoseries (2) and to the P ...
... environment and play important roles in processes such as cell growth and differentiation. In addition, viruses, bacteria, and bacterial toxins use the protruding carbohydrate moieties as specific sites of attachment in infectious processes. Glycolipids belonging to the globoseries (2) and to the P ...
GRANULOMATOUS INFLAMMATION Lecture1
... indigestible antigenic material in macrophages Antigen presentation on cell membrane to appropriate CD4+TH1 lymphocytes, causing them to become activated. The responding T cells produce cytokines, such as IL-2, and IFN-γ, IFN-γ is important in activating macrophages and transforming them into ep ...
... indigestible antigenic material in macrophages Antigen presentation on cell membrane to appropriate CD4+TH1 lymphocytes, causing them to become activated. The responding T cells produce cytokines, such as IL-2, and IFN-γ, IFN-γ is important in activating macrophages and transforming them into ep ...
HIVART_4 - I-Tech
... Derived from naïve T8 cells, which recognize viral antigens in context of MHC class I presentation Directly destroy infected cell Activity augmented by Th1 response ...
... Derived from naïve T8 cells, which recognize viral antigens in context of MHC class I presentation Directly destroy infected cell Activity augmented by Th1 response ...
Slide 1
... to enteral administration in terms of clinical outcomes,. The vast majority of trials available in the literature delivered micronutrients intravenously, with the intravenous route seen as the only reliable method by which micronutrients can be administered in the critically ill . Absorption by the ...
... to enteral administration in terms of clinical outcomes,. The vast majority of trials available in the literature delivered micronutrients intravenously, with the intravenous route seen as the only reliable method by which micronutrients can be administered in the critically ill . Absorption by the ...
Introduction: Biology Today Chapter 1
... Anatomical details of the spleen are described in Chapter 22 of the ...
... Anatomical details of the spleen are described in Chapter 22 of the ...
Raulet, D. H. and N. Guerra. 2009. Oncogenic stress sensed by the immune system: role of natural killer cell receptors. Nat Rev Immunol 9:568-580.
... human disease include cervical carcinoma, some lymphomas and Kaposi’s sarcoma. In these instances, the transformed cell may express non-self antigens encoded by the pathogen that can be targeted by B and T cells, in the same way that they might respond during an infection. Other cancers arise by spo ...
... human disease include cervical carcinoma, some lymphomas and Kaposi’s sarcoma. In these instances, the transformed cell may express non-self antigens encoded by the pathogen that can be targeted by B and T cells, in the same way that they might respond during an infection. Other cancers arise by spo ...
Moffitt`s Clinical Trials for Patients with Lung Cancer
... melanoma and renal cancer, but no one thought it would be efficacious for treating lung cancer. We had been looking at immunotherapy approaches that focused on the lymphoid compartment and vaccines that would expand tumor-specific T cells. Scott Antonia, MD, PhD However, response rates with anti-PD- ...
... melanoma and renal cancer, but no one thought it would be efficacious for treating lung cancer. We had been looking at immunotherapy approaches that focused on the lymphoid compartment and vaccines that would expand tumor-specific T cells. Scott Antonia, MD, PhD However, response rates with anti-PD- ...
Hooper LV, Macpherson AJ.. Immune adaptations that maintain
... harbours a diversity of saccharolytic enzymes that complement the limited saccharolytic diversity encoded in the host genome. commensal microorganisms such as Bacteroides thetaiotaomicron are uniquely adapted for harvesting luminal nutrients, as shown by the presence of an unusually large number of ...
... harbours a diversity of saccharolytic enzymes that complement the limited saccharolytic diversity encoded in the host genome. commensal microorganisms such as Bacteroides thetaiotaomicron are uniquely adapted for harvesting luminal nutrients, as shown by the presence of an unusually large number of ...
Morphology of the air‐breathing stomach of the catfish Hypostomus
... the epithelial cells, apart from its typical organelles, contains electron-dense and lamellar bodies at different stages of maturation, which form the sites of accumulation of surfactant. Small, electron-dense vesicles containing acidic mucopolysaccharides are found in the apical parts of some respi ...
... the epithelial cells, apart from its typical organelles, contains electron-dense and lamellar bodies at different stages of maturation, which form the sites of accumulation of surfactant. Small, electron-dense vesicles containing acidic mucopolysaccharides are found in the apical parts of some respi ...
Adaptive Immune Responses in the Intestinal Mucosa of
... Clinically CC and LC cannot be differentiated from each other. The main symptom of both conditions is chronic non-bloody, watery diarrhoea, and is often associated with nocturnal diarrhoea (9). Abdominal pain and weight loss is significantly common. Furthermore faecal incontinence may affect these p ...
... Clinically CC and LC cannot be differentiated from each other. The main symptom of both conditions is chronic non-bloody, watery diarrhoea, and is often associated with nocturnal diarrhoea (9). Abdominal pain and weight loss is significantly common. Furthermore faecal incontinence may affect these p ...
Garcia 1..9
... immunizations and cART interruption DC–HIV-1 patients experienced significant changes of pVL setpoint after cART interruption compared with DC-controls. The drop in pVL setpoint after the second cART interruption is shown in Table 2 and Fig. 2 (A and B). The results of the analysis did not change at ...
... immunizations and cART interruption DC–HIV-1 patients experienced significant changes of pVL setpoint after cART interruption compared with DC-controls. The drop in pVL setpoint after the second cART interruption is shown in Table 2 and Fig. 2 (A and B). The results of the analysis did not change at ...
the role of dual specificity phosphatase
... (Dong et al., 2002). Any disruption in this regulation may result in chronic inflammation potentially leading to inflammatory and autoimmune diseases. The immune cells are tightly regulated at multiple levels during the activation as well as the termination of immune responses. This regulation invol ...
... (Dong et al., 2002). Any disruption in this regulation may result in chronic inflammation potentially leading to inflammatory and autoimmune diseases. The immune cells are tightly regulated at multiple levels during the activation as well as the termination of immune responses. This regulation invol ...
MHC Class II Molecules
... Major Histocompatibility Complex Molecules The gene complex was first identified based on the ability of a donor to accept grafts from the recipient sharing the same MHC ...
... Major Histocompatibility Complex Molecules The gene complex was first identified based on the ability of a donor to accept grafts from the recipient sharing the same MHC ...
a,
... Are coded for by genes of the major histocompatibility complex (MHC) and are unique to an individual ...
... Are coded for by genes of the major histocompatibility complex (MHC) and are unique to an individual ...
Neisseria gonorrhoeae Variation of Lipooligosaccharide Directs Dendritic Cell–Induced T Helper Responses
... GalNAc and is present on urethral epithelial cells where it facilitates entry of GC that express the complementary glycan structures [24]. However, this C-type lectin is not expressed on DCs. DCs do express the GalNAc-specific C-type lectin MGL [25]. We hypothesized that this lectin might be the maj ...
... GalNAc and is present on urethral epithelial cells where it facilitates entry of GC that express the complementary glycan structures [24]. However, this C-type lectin is not expressed on DCs. DCs do express the GalNAc-specific C-type lectin MGL [25]. We hypothesized that this lectin might be the maj ...
Understanding Immunity by Tracing Thymocyte Development
... AAI Curriculum Unit: Understanding Immunity By Tracing T-cell Development Appendix I: 50 Sets of 400 Randomly Generated Tri-Peptides 1. mdn yqf ntg hyy nhm ctq nff ege svs cef smi vhn syy tsq tps ink tlq tng nlv kgl aqc nqq rqy gsa ccw fsg grg lww vgs qll fmv tyy wdg iss slk ppr tgs eds yck tpw k ...
... AAI Curriculum Unit: Understanding Immunity By Tracing T-cell Development Appendix I: 50 Sets of 400 Randomly Generated Tri-Peptides 1. mdn yqf ntg hyy nhm ctq nff ege svs cef smi vhn syy tsq tps ink tlq tng nlv kgl aqc nqq rqy gsa ccw fsg grg lww vgs qll fmv tyy wdg iss slk ppr tgs eds yck tpw k ...