Radioimmunotherapy Is More Effective than Antifungal Treatment
... by Dadachova and Casadevall [10]). We observed that melanization of C. neoformans before infection did not increase the resistance of C. neoformans to RIT in vivo. Possible explanations for this may include the delicate balance existing in vivo between daughter cells that are not melanized right aft ...
... by Dadachova and Casadevall [10]). We observed that melanization of C. neoformans before infection did not increase the resistance of C. neoformans to RIT in vivo. Possible explanations for this may include the delicate balance existing in vivo between daughter cells that are not melanized right aft ...
IgG and IgA Antibody Profiling with the PEPperCHIP
... corresponding antibody. Other strong IgG responses were directed against various epitopes of herpes simplex virus, a common pathogen with a very high rate of infestation. Less strong IgG responses were observed against multiple epitopes of Toxoplasma gondii, a parasitic protozoan that causes toxopla ...
... corresponding antibody. Other strong IgG responses were directed against various epitopes of herpes simplex virus, a common pathogen with a very high rate of infestation. Less strong IgG responses were observed against multiple epitopes of Toxoplasma gondii, a parasitic protozoan that causes toxopla ...
Jenny Walldén Studies of immunological risk factors in type 1 diabetes
... which, when activated, proliferate and develop into effector cells secreting cytokines and antibodies, respectively 1. T cells can be divided into two different populations based on their expression of the cell surface proteins cluster of differentiation (CD) 4 or CD8. 1. B cells differentiates into ...
... which, when activated, proliferate and develop into effector cells secreting cytokines and antibodies, respectively 1. T cells can be divided into two different populations based on their expression of the cell surface proteins cluster of differentiation (CD) 4 or CD8. 1. B cells differentiates into ...
030710 Medium- and Large
... constitute a genetic risk factor for giant-cell arteritis and polymyalgia rheumatica,24 providing indirect evidence of the crucial role of antigen stimulation of CD4+ T cells.11 Moreover, clonally expanded populations of CD4+ T cells with identical antigen receptors have been isolated from distinct ...
... constitute a genetic risk factor for giant-cell arteritis and polymyalgia rheumatica,24 providing indirect evidence of the crucial role of antigen stimulation of CD4+ T cells.11 Moreover, clonally expanded populations of CD4+ T cells with identical antigen receptors have been isolated from distinct ...
Chapter 43 Internal Defense
... antibodies, immunoglobulins (Ig), in response to the specific antigens that activated them Copyright © 2005 Brooks/Cole — Thomson Learning ...
... antibodies, immunoglobulins (Ig), in response to the specific antigens that activated them Copyright © 2005 Brooks/Cole — Thomson Learning ...
HELLP syndrome: a complication or a new autoimmune
... TNF-α, have been found in women suffering from recurrent spontaneous abortion (RSA) [7, 8]. Evidence suggests that inflammatory cytokines deriving from placenta such as TNF-α, interleukin IL-6 and IL-10 are increased during pregnancy-induced hypertension [8]. However, it is well known that immune ce ...
... TNF-α, have been found in women suffering from recurrent spontaneous abortion (RSA) [7, 8]. Evidence suggests that inflammatory cytokines deriving from placenta such as TNF-α, interleukin IL-6 and IL-10 are increased during pregnancy-induced hypertension [8]. However, it is well known that immune ce ...
Sex steroid hormones
... The prevalence of autoimmune diseases is higher in women than men, while for cardiovascular disease, there is a male predominance. The sexual dimorphism of autoimmune and cardiovascular diseases probably relates to a number of factors, e.g. difference in exposure to risk factors and response to ther ...
... The prevalence of autoimmune diseases is higher in women than men, while for cardiovascular disease, there is a male predominance. The sexual dimorphism of autoimmune and cardiovascular diseases probably relates to a number of factors, e.g. difference in exposure to risk factors and response to ther ...
Tissue after Acute Infection Ex Vivo Cytokine Gene Expression in
... gene product. For example, Nef induced IL-2 in T cells stimulated with CD3 and CD28 (22) but down-regulated IL-2 in T cells treated with PHA or PMA (21). Another study reported no differences in the levels or kinetics of cytokine secretion between uninfected and acutely HIV-infected IL-2-stimulated ...
... gene product. For example, Nef induced IL-2 in T cells stimulated with CD3 and CD28 (22) but down-regulated IL-2 in T cells treated with PHA or PMA (21). Another study reported no differences in the levels or kinetics of cytokine secretion between uninfected and acutely HIV-infected IL-2-stimulated ...
Cytokine Atlas - Thermo Fisher Scientific
... cardiovascular diseases (CVD), for which cytokines have become important biomarkers. Numerous pro- and anti-inflammatory cytokines are used to help stage and diagnose various cardiovascular diseases. The pro-inflammatory cytokines IL-1β, IL-6, IL-8, IL-15, IL-18, CCL2 (MCP-1), and TNFα are released ...
... cardiovascular diseases (CVD), for which cytokines have become important biomarkers. Numerous pro- and anti-inflammatory cytokines are used to help stage and diagnose various cardiovascular diseases. The pro-inflammatory cytokines IL-1β, IL-6, IL-8, IL-15, IL-18, CCL2 (MCP-1), and TNFα are released ...
B cell sub-types following acute malaria and associations with
... Box 0811, San Francisco, CA 94110, USA Full list of author information is available at the end of the article ...
... Box 0811, San Francisco, CA 94110, USA Full list of author information is available at the end of the article ...
Alternative Activation Is an Innate Response to Injury That Requires CD4
... via the engagement of TLRs (19) or by the IFNs (!" or #) (20) during the early phase of an acute microbial infection is increasingly well understood. Subsequent Th1 cell development promotes more effective macrophage killing that is essential in the control of many intracellular pathogens (21). We w ...
... via the engagement of TLRs (19) or by the IFNs (!" or #) (20) during the early phase of an acute microbial infection is increasingly well understood. Subsequent Th1 cell development promotes more effective macrophage killing that is essential in the control of many intracellular pathogens (21). We w ...
Preliminary evidence that the novel host-derived immunostimulant EP67 can act as a mucosal adjuvant
... clinical trials. Thus, numerous experimental adjuvants are being developed for clinical use with all routes of mucosal immunization. Majority of experimental mucosal adjuvants to date are based on pathogen-associated molecular pattern (PAMP) agonists that stimulate innate immune responses through pa ...
... clinical trials. Thus, numerous experimental adjuvants are being developed for clinical use with all routes of mucosal immunization. Majority of experimental mucosal adjuvants to date are based on pathogen-associated molecular pattern (PAMP) agonists that stimulate innate immune responses through pa ...
Role of the Endocannabinoid System in the Neuroendocrine
... The CB2 receptors were previously thought to be predominantly expressed in immune cells in the periphery and act to modulate immune function [16]. CB2 receptors are also expressed in tonsils, bone marrow, thymus, pancreas, adult rat retina, and peripheral nerve terminals in the mouse vas deferens [1 ...
... The CB2 receptors were previously thought to be predominantly expressed in immune cells in the periphery and act to modulate immune function [16]. CB2 receptors are also expressed in tonsils, bone marrow, thymus, pancreas, adult rat retina, and peripheral nerve terminals in the mouse vas deferens [1 ...
Analysis of immune deviation elicited by antigens injected
... space elicits immune deviation, resembling ACAID. However, the transplanted tissues in those experiments were eye derived and therefore probably represent immune-privileged tissues, which may considerably alter the observed immune responses. Anatomically, the subretinal space is a potential space lo ...
... space elicits immune deviation, resembling ACAID. However, the transplanted tissues in those experiments were eye derived and therefore probably represent immune-privileged tissues, which may considerably alter the observed immune responses. Anatomically, the subretinal space is a potential space lo ...
case report measles-mumps-rubella vaccination induced
... in a faster increase in platelet counts. Intravenous immunoglobulin, which blocks Fc-receptors on the macrophages of the reticuloendothelial system, is also the first line treatment for ITP in an emergency setting and proves effective when used at a high dose of 1-2 g/kg (Labarque and Van Geet, 2014 ...
... in a faster increase in platelet counts. Intravenous immunoglobulin, which blocks Fc-receptors on the macrophages of the reticuloendothelial system, is also the first line treatment for ITP in an emergency setting and proves effective when used at a high dose of 1-2 g/kg (Labarque and Van Geet, 2014 ...
Hemodialysis Catheters
... Duration of antimicrobial therapy for CRB • Uncertain. It depends on clinical, microbiologic features and whether the catheter is removed • Treat uncomplicated CRB for two or three weeks. • Treat uncomplicated CRB due to S. Aureus for four weeks. • If there is evidence of metastatic infection, use ...
... Duration of antimicrobial therapy for CRB • Uncertain. It depends on clinical, microbiologic features and whether the catheter is removed • Treat uncomplicated CRB for two or three weeks. • Treat uncomplicated CRB due to S. Aureus for four weeks. • If there is evidence of metastatic infection, use ...
Reactive And Enteropathic Arthritis
... With respect to ReA, the most common triggering urogenital agents are urogenital (Chlamydia spp) and enteric (Shigella, Salmonella, Yersinia, and Campylobacterspp) pathogens. Substantial regional differences are evident, however, particularly with regard to he enteric pathogens. Chlamydia spp are re ...
... With respect to ReA, the most common triggering urogenital agents are urogenital (Chlamydia spp) and enteric (Shigella, Salmonella, Yersinia, and Campylobacterspp) pathogens. Substantial regional differences are evident, however, particularly with regard to he enteric pathogens. Chlamydia spp are re ...
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... (Walker & Fraser, 1957). Relatively normal elevation and fusion can be achieved in treated foetuses by excising the tongue (Walker & Quarles, 1976). In any event, although there is known to be a strong embryonic effect vis-a-vis the relationship of H-2K k (or closely linked genes) and high susceptib ...
... (Walker & Fraser, 1957). Relatively normal elevation and fusion can be achieved in treated foetuses by excising the tongue (Walker & Quarles, 1976). In any event, although there is known to be a strong embryonic effect vis-a-vis the relationship of H-2K k (or closely linked genes) and high susceptib ...
Maternal immune characteristics and innate immune responses in the
... The mechanistic factors responsible for the increase in allergic diseases are still not fully understood, but a reduced microbial stimulation seems to be one of the key issues. Research is now aiming at investigating the relationship between the innate immune system, involving the toll-like receptor ...
... The mechanistic factors responsible for the increase in allergic diseases are still not fully understood, but a reduced microbial stimulation seems to be one of the key issues. Research is now aiming at investigating the relationship between the innate immune system, involving the toll-like receptor ...
The role of lysosomal cysteine proteases in crustacean immune
... the loss of homeostasis in enzyme activity leads to pathologies. As with other LCPs, cathepsins are also synthesized as inactive precursors that become activated after a limited proteolysis that removes the N-terminal propeptide. This propeptide is located on the active site (Turk et al., 2001), and ...
... the loss of homeostasis in enzyme activity leads to pathologies. As with other LCPs, cathepsins are also synthesized as inactive precursors that become activated after a limited proteolysis that removes the N-terminal propeptide. This propeptide is located on the active site (Turk et al., 2001), and ...