Intravaginal Zinc Oxide Tetrapod Nanoparticles as Novel
... erpes simplex virus-2 is an enveloped dsDNA virus. Globally, it is one of the most common human pathogens. HSV-2 has been found to cause mucosal, ocular, and neurologic infections; however, it typically causes genital infections (genital herpes) manifesting as severe lesions in and around the genita ...
... erpes simplex virus-2 is an enveloped dsDNA virus. Globally, it is one of the most common human pathogens. HSV-2 has been found to cause mucosal, ocular, and neurologic infections; however, it typically causes genital infections (genital herpes) manifesting as severe lesions in and around the genita ...
- Journal of Allergy and Clinical Immunology
... An interesting debate about the immunologic mechanisms potentially underlying the protection against allergies mediated by living in a less hygienic environment is ongoing. One mechanism frequently associated with the hygiene hypothesis is the skewing of the TH1/TH2 balance away from allergy-promoti ...
... An interesting debate about the immunologic mechanisms potentially underlying the protection against allergies mediated by living in a less hygienic environment is ongoing. One mechanism frequently associated with the hygiene hypothesis is the skewing of the TH1/TH2 balance away from allergy-promoti ...
SAG-2 oral rabies vaccine A. J. BARRAT
... mice especially by the intracerebral route (leblois et a/. 1988). The innocuity for cats and dogs at dosages that are 10 times greater than that designated for field application was shown to be complete. The short-term innocuity for the red fox of a dose greater than that intended for use in the fie ...
... mice especially by the intracerebral route (leblois et a/. 1988). The innocuity for cats and dogs at dosages that are 10 times greater than that designated for field application was shown to be complete. The short-term innocuity for the red fox of a dose greater than that intended for use in the fie ...
IMMUNOBIOLOGY B cells in early and chronic HIV infection
... study on B-cell responses following ART, Morris and colleagues described a rapid loss of HIVspecific B cells (actively secreting plasmablasts) during therapy, followed by a more gradual decrease in antibody titers against HIV in chronically infected individuals; the loss was even more rapid in early ...
... study on B-cell responses following ART, Morris and colleagues described a rapid loss of HIVspecific B cells (actively secreting plasmablasts) during therapy, followed by a more gradual decrease in antibody titers against HIV in chronically infected individuals; the loss was even more rapid in early ...
Complement-mediated “bystander” damage initiates host NLRP3
... Complement mediated phagocytosis by macrophages induces the release of IL-1β and IL-18. To study the effect of phagocytosis on inflammasome activation by macrophages, a variety of complement activating particles were added to LPS-primed murine macrophages, and the release of IL-1β was measured in su ...
... Complement mediated phagocytosis by macrophages induces the release of IL-1β and IL-18. To study the effect of phagocytosis on inflammasome activation by macrophages, a variety of complement activating particles were added to LPS-primed murine macrophages, and the release of IL-1β was measured in su ...
Vasculitis: Attack of the Leukocytes
... The choice of treatment for your vasculitis depends on the severity of the vasculitis, your general health, and your past reactions (positive and negative) to medications. Many cases of vasculitis do not require treatment. For example, a few spots on the skin now and then (if not combined with other ...
... The choice of treatment for your vasculitis depends on the severity of the vasculitis, your general health, and your past reactions (positive and negative) to medications. Many cases of vasculitis do not require treatment. For example, a few spots on the skin now and then (if not combined with other ...
An Immune System Perspective on Ecosystem Management
... rely on the accumulation of knowledge over many generations, and knowledge is transmitted culturally by taboos, religions, rituals, and the like. These systems are able to integrate long-term knowledge into their daily practices. For example, traditional fishery systems are characterized by rules an ...
... rely on the accumulation of knowledge over many generations, and knowledge is transmitted culturally by taboos, religions, rituals, and the like. These systems are able to integrate long-term knowledge into their daily practices. For example, traditional fishery systems are characterized by rules an ...
Corticotropin-Releasing Hormone and Its Structurally Related
... TRESS ACTIVATES THE hypothalamic-pituitaryadrenal axis through the release of CRH leading to secretion of catecholamines and glucocorticoids; these, in turn, suppress the immune response (1). CRH is a 41amino-acid peptide synthesized in the hypothalamus and mediates its effects through at least two ...
... TRESS ACTIVATES THE hypothalamic-pituitaryadrenal axis through the release of CRH leading to secretion of catecholamines and glucocorticoids; these, in turn, suppress the immune response (1). CRH is a 41amino-acid peptide synthesized in the hypothalamus and mediates its effects through at least two ...
The Trojan exosome hypothesis - Gene
... We propose that retroviruses exploit a cell-encoded pathway of intercellular vesicle traffic, exosome exchange, for both the biogenesis of retroviral particles and a low-efficiency but mechanistically important mode of infection. This Trojan exosome hypothesis reconciles current paradigms of retrovi ...
... We propose that retroviruses exploit a cell-encoded pathway of intercellular vesicle traffic, exosome exchange, for both the biogenesis of retroviral particles and a low-efficiency but mechanistically important mode of infection. This Trojan exosome hypothesis reconciles current paradigms of retrovi ...
Macrophage programming and host responses to bacterial infection Xiao Wang 王潇
... subgroups when they are stimulated in polarizing conditions. Depending on the distinct microenvironmental signals, macrophages can be polarized into classically activated macrophages (M1) or alternatively activated macro2 ...
... subgroups when they are stimulated in polarizing conditions. Depending on the distinct microenvironmental signals, macrophages can be polarized into classically activated macrophages (M1) or alternatively activated macro2 ...
What is new on the horizon? - Australia Alopecia Areata Foundation
... include topical minoxidil, anthralin, and phototherapy with psoralen plus near ultraviolet light (UVA) therapy. Additional second-line therapies include systemic treatment with oral glucocorticoids, sulfasalazine, cyclosporine, methotrexate, or combination therapy (1,4,9). Other therapies that have ...
... include topical minoxidil, anthralin, and phototherapy with psoralen plus near ultraviolet light (UVA) therapy. Additional second-line therapies include systemic treatment with oral glucocorticoids, sulfasalazine, cyclosporine, methotrexate, or combination therapy (1,4,9). Other therapies that have ...
Hemophagocytosis in adults (Hemophagocytic Syndrome) Brady Miller Hematology Oncology Fellow
... then mutually stimulate each other by receptor interaction as well as by secretion of inflammatory cytokines and chemokines. • In healthy individuals this leads to killing of infected cells, removal of antigen, and then termination of the immune response. • In HLH, there is an inherited or acquired ...
... then mutually stimulate each other by receptor interaction as well as by secretion of inflammatory cytokines and chemokines. • In healthy individuals this leads to killing of infected cells, removal of antigen, and then termination of the immune response. • In HLH, there is an inherited or acquired ...
GABAergic System in b-Cells: From Autoimmunity Target
... required to achieve insulin independence. The islet transplant field is still struggling with high numbers of transplanted islets succumbing to peritransplant apoptosis and the subsequent loss of islet mass (16). However, a successful or even partially functioning islet transplant has been shown to h ...
... required to achieve insulin independence. The islet transplant field is still struggling with high numbers of transplanted islets succumbing to peritransplant apoptosis and the subsequent loss of islet mass (16). However, a successful or even partially functioning islet transplant has been shown to h ...
Serologic Analysis of the IgG Antibody Response in
... in Germany. Initially, given as a single dose, this recommendation was modified in favor of a 2-dose regimen in Germany by 2009.1–3 In contrast to VZV wild-type infection, which typically confers lifelong immunity, breakthrough infections can occur months to years after VZV immunization and are caus ...
... in Germany. Initially, given as a single dose, this recommendation was modified in favor of a 2-dose regimen in Germany by 2009.1–3 In contrast to VZV wild-type infection, which typically confers lifelong immunity, breakthrough infections can occur months to years after VZV immunization and are caus ...
Infection Leishmania major Immunity Against JNK1 Is Required for T
... Polarized differentiation of CD4⫹ T cells toward one Th subset over the other can be influenced by a number of factors, including the cytokine environment, priming Ag dose, Ag/TCR interaction affinity, and costimulatory signals (reviewed in Refs. 6 and 7). The molecular mechanisms by which these fac ...
... Polarized differentiation of CD4⫹ T cells toward one Th subset over the other can be influenced by a number of factors, including the cytokine environment, priming Ag dose, Ag/TCR interaction affinity, and costimulatory signals (reviewed in Refs. 6 and 7). The molecular mechanisms by which these fac ...
Prescribing Information BayRho
... Dose is prepared by cold ethanol fractionation from human plasma. The immune globulin is isolated from solubilized Cohn fraction II. The fraction II solution is adjusted to a final concentration of 0.3% tri-n-butyl phosphate (TNBP) and 0.2% sodium cholate. After the addition of solvent (TNBP) and de ...
... Dose is prepared by cold ethanol fractionation from human plasma. The immune globulin is isolated from solubilized Cohn fraction II. The fraction II solution is adjusted to a final concentration of 0.3% tri-n-butyl phosphate (TNBP) and 0.2% sodium cholate. After the addition of solvent (TNBP) and de ...
The Immune Response to Helicobacter pylori
... The vacuolating cytotoxin A (VacA) virulence factor has long been associated with host damage by forming pores in host cell membranes, disrupting membrane trafficking and inducing apoptosis. Mechanisms associated with apoptosis include VacA-induced inhibition of Stat3 and Bcl-2 cell survival protein ...
... The vacuolating cytotoxin A (VacA) virulence factor has long been associated with host damage by forming pores in host cell membranes, disrupting membrane trafficking and inducing apoptosis. Mechanisms associated with apoptosis include VacA-induced inhibition of Stat3 and Bcl-2 cell survival protein ...
Progress in the fight against Inflammatory Diseases and Cancer
... Our major research interest is understanding how the innate immune system senses viruses and subsequently signals altered gene expression. The innate immune system responds to viruses using several classes of germline-encoded pattern recognition receptors (PRRs) to recognise pathogen-associated mole ...
... Our major research interest is understanding how the innate immune system senses viruses and subsequently signals altered gene expression. The innate immune system responds to viruses using several classes of germline-encoded pattern recognition receptors (PRRs) to recognise pathogen-associated mole ...
STUDIES OF MUCOSAL IMMUNE REGULATION ANNE LAHDENPERÄ
... Background: Celiac disease (CD) and type 1 diabetes (T1D) are two chronic autoimmune diseases with increasing incidence worldwide. A combination of genetic, environmental and immunological factors is considered to be involved in development of the diseases, even though the exact disease mechanisms s ...
... Background: Celiac disease (CD) and type 1 diabetes (T1D) are two chronic autoimmune diseases with increasing incidence worldwide. A combination of genetic, environmental and immunological factors is considered to be involved in development of the diseases, even though the exact disease mechanisms s ...
Differential expression of surface membrane Trypanosoma congolense
... · N'Dama than those of the Baran cattle. These enhancements were expressed as both increases in PBM population and mean fluorescence expressed per cell (an indicator of number of epitopes per cell). Fig. 1 shows the differential graphical expression of the C3bi receptor on stimulated PBM of one N'Da ...
... · N'Dama than those of the Baran cattle. These enhancements were expressed as both increases in PBM population and mean fluorescence expressed per cell (an indicator of number of epitopes per cell). Fig. 1 shows the differential graphical expression of the C3bi receptor on stimulated PBM of one N'Da ...