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Unit 8 Communicable Diseases
Unit 8 Communicable Diseases

... Smallest known type of infectious agent 1/2 to 1/100 the size of the very smallest bacterium Consist of an inner core of genetic material surrounded by a protective protein shell and are entirely dependent on living cells for survival and reproduction. ...
Major Players in the Immune System
Major Players in the Immune System

Chicken Pox
Chicken Pox

... fluid from blister can spread virus ...
chapter16
chapter16

... inserted into the lumen of the ER MHC I proteins bind to the peptides and then are displayed on the cell’s surface CD8+ Tc cells recognize these microbial peptides and kill the cell Puncturing holes in the membrane with perforin Inducing a death signal that causes DNA fragmentation ...
Study Guide 11 - Innate Immunity
Study Guide 11 - Innate Immunity

... What are the first‐line defenses?  What is the function the sensor systems in innate immunity?  What are toll‐like receptors?  What is the complement system?  What is the role of phagocytes?  What are cytokines?  What triggers inflammation?  Describe the functions of lysozyme, transferrin, and gastr ...
Another person Direct contact: shaking hands 1. 2. Contaminated
Another person Direct contact: shaking hands 1. 2. Contaminated

... naturally in the soil or water. ...
1-overview
1-overview

... How do immune cells communicate? Extensive cell-cell contact Membrane protein interaction Immune synapse ...
The History of Antibodies
The History of Antibodies

... antibodies are proving themselves to be remarkably effective in the clinic, particularly for the treatment of certain types of cancer and autoimmune disease. As of 2015, the global monoclonal antibody market is estimated at US $75 billion, and this figure is projected to increase substantially over ...
open lecture in Powerpoint
open lecture in Powerpoint

... • Upon completion of this lesson, the student will be able to – differentiate the immune function across the lifespan. – determine the different effects of inflammation. – describe the four mechanisms of hypersensitivity. – contrast the concepts of autoimmunity, infection, and immunosuppression. – d ...
print version
print version

... protection. The second line of defence, the adaptive immune system, provides lifelong immunity; it “remembers” germs or cancers so that it can protect your body against similar attacks in the future. If the immune system is the cancer warrior, then T-cells are the key weapons in its arsenal. They at ...
Lesson 1: The Immune System - Lecture Notes | Vaccine Education
Lesson 1: The Immune System - Lecture Notes | Vaccine Education

... • Antibodies are programmed to recognize and bind to the antigen posing a threat to the body so that it can be recognized and destroyed. • Antibodies are proteins produced by B lymphocytes to neutralize antigens and prepare them for destruction by phagocytes. They can also be known as immunoglobul ...
biopresibstandards
biopresibstandards

...  Viruses carry out very few processes themselves. They rely instead on a host cell such as a human cell to carry out the processes for them. It is not possible to block these processes with an antibiotic without also harming the human cells. For this reason virus diseases cannot be treated with ant ...
The Immune System
The Immune System

... • Recall: if our bodies contain the antibodies for specific antigens, we have what is called “immunity”. • We develop immunity when we get sick and our body makes antibodies to fight an antigen. • We can also obtain immunity by receiving a vaccine (vaccination). ...
Immune System Notes
Immune System Notes

... B LYMPHOCYTES (B cells) make ANTIBODIES IMMUNOGLOBULINS (proteins) Antibodies weaken pathogens and mark for phagocytic cells to “eat” 2. CELL-MEDIATED IMMUNE RESPONSE- important in VIRUSES, CANCER, TRANSPLANTS • Uses T LYMPHOCYTES (T cells) • Made in bone marrow; become T cells in thymus 1. CYTOTOXI ...
Cancer vaccines: up, down, … up again?
Cancer vaccines: up, down, … up again?

... Toll-like receptor ligands, or by vaccinating donors of transplant recipients who have a healthy immune system as opposed to patients who may be immunocompromised either from the cancer or from therapy.3 Alternatively, vaccines could be used in combination with agents that inhibit the immunosuppress ...
the immune system - World of Teaching
the immune system - World of Teaching

... • At the clone stage antibodies do not leave the Bcells. • The abs are embedded in the plasma membrane of the cell and are called antibody receptors. • When the receptors in the membrane recognise and antigen on the surface of the pathogen the B-cell divides rapidly. • The antigens are presented to ...
THE IMMUNE SYSTEM
THE IMMUNE SYSTEM

... • At the clone stage antibodies do not leave the Bcells. • The abs are embedded in the plasma membrane of the cell and are called antibody receptors. • When the receptors in the membrane recognise and antigen on the surface of the pathogen the B-cell divides rapidly. • The antigens are presented to ...
THE IMMUNE SYSTEM
THE IMMUNE SYSTEM

... • At the clone stage antibodies do not leave the Bcells. • The abs are embedded in the plasma membrane of the cell and are called antibody receptors. • When the receptors in the membrane recognise and antigen on the surface of the pathogen the B-cell divides rapidly. • The antigens are presented to ...
Document
Document

... IVIG is purified IgG prepared from pooled plasma of thousands of people. It is used to supplement the immune systems of people with a variety of immune deficiency disorders. ...
35_Organ-specific autoimmune diseases
35_Organ-specific autoimmune diseases

... white matter of the central nervous system ...
Causes of Autoimmune Diseases
Causes of Autoimmune Diseases

... immunosuppression like high doses of prednisolone or cytotoxic therapy. Both cause non-specific immunosuppression and the patient may suffer from opportunistic infections. 3- Now a days, antithymocytes antibodies are used. 4- Repeated blood transfusion in small doses from the same donor before trans ...
General Pathology: Acute Inflammation
General Pathology: Acute Inflammation

... • IgA, largest quantities found in secretions, some also found in blood, usually a dimer • IgE, normally small amounts in blood, bind to surface of mast cells and play a role in allergic responses • IgD, normally not found in blood, expressed on the surface of some B-cells ...
HOST DEFENSE COURSE OBJECTIVES At the completion of Host
HOST DEFENSE COURSE OBJECTIVES At the completion of Host

Poster - IRMACS Centre - Simon Fraser University
Poster - IRMACS Centre - Simon Fraser University

... III. iReceptor is the First Bioinformatic Platform Integrating Distributed Immune Repertoire “Big” Data Sets ...
Immunology of CELIAC DISEASE
Immunology of CELIAC DISEASE

... –T-Helper Cell – has antigen-receptors, releases cytokines –Natural Killer Cell – kills macrophage –Cytotoxic T-Cell – kills cells that produce foreign antigens such as cells infected by viruses –B-Cell – creates antibodies. •Antigen – invading microbe •Antibody – protein that fights bacteria and vi ...
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Immunosuppressive drug

For a list of immunosuppressive drugs, see the transplant rejection page.Immunosuppressive drugs or immunosuppressive agents or antirejection medications are drugs that inhibit or prevent activity of the immune system. They are used in immunosuppressive therapy to: Prevent the rejection of transplanted organs and tissues (e.g., bone marrow, heart, kidney, liver) Treat autoimmune diseases or diseases that are most likely of autoimmune origin (e.g., rheumatoid arthritis, multiple sclerosis, myasthenia gravis, systemic lupus erythematosus, sarcoidosis, focal segmental glomerulosclerosis, Crohn's disease, Behcet's Disease, pemphigus, and ulcerative colitis). Treat some other non-autoimmune inflammatory diseases (e.g., long term allergic asthma control).A common side-effect of many immunosuppressive drugs is immunodeficiency, because the majority of them act non-selectively, resulting in increased susceptibility to infections and decreased cancer immunosurveillance. There are also other side-effects, such as hypertension, dyslipidemia, hyperglycemia, peptic ulcers, lipodystrophy, moon face, liver and kidney injury. The immunosuppressive drugs also interact with other medicines and affect their metabolism and action. Actual or suspected immunosuppressive agents can be evaluated in terms of their effects on lymphocyte subpopulations in tissues using immunohistochemistry.Immunosuppressive drugs can be classified into five groups: glucocorticoids cytostatics antibodies drugs acting on immunophilins other drugs.
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